| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingjing Wu, Cheng Zhou, Tao Guo, Xiaojun Guan, Ting Gao, Xueqin Bai, Haoting Wu, Jingwen Chen, Jiaqi Wen, Xiaocao Liu, Luyan Gu, Zhe Song, Min Xuan, Quanquan Gu, Peiyu Huang, Jiali Pu, Baorong Zhang, Xiaojun Xu, Minming Zhan. Cholinergic relevant functional reactivity is associated with dopamine responsiveness of tremor in Parkinson's disease. Brain imaging and behavior. 2022-01-01. PMID:34973120. |
through investigating the alterations of cholinergic and dopaminergic network during levodopa administration, we aimed at exploring the mechanisms of differed dopamine responsiveness of parkinsonian tremor. |
2022-01-01 |
2023-08-13 |
Not clear |
| Masahiko Nishioka, Taisuke Kamada, Atsushi Nakata, Naoko Shiokawa, Aoi Kinoshita, Toshimichi Hat. Intra-dorsal striatal acetylcholine M1 but not dopaminergic D1 or glutamatergic NMDA receptor antagonists inhibit consolidation of duration memory in interval timing. Behavioural brain research. vol 419. 2021-12-10. PMID:34800548. |
muscarinic 1 (m1) cholinergic receptors as well as dopamine and glutamate receptors are important for neural plasticity in the dorsal striatum. |
2021-12-10 |
2023-08-13 |
rat |
| Kate Thomson, Tamsin Kelly, Cindy Karouta, Ian Morgan, Regan Ashb. Insights into the mechanism by which atropine inhibits myopia: evidence against cholinergic hyperactivity and modulation of dopamine release. British journal of pharmacology. vol 178. issue 22. 2021-12-08. PMID:34302355. |
insights into the mechanism by which atropine inhibits myopia: evidence against cholinergic hyperactivity and modulation of dopamine release. |
2021-12-08 |
2023-08-13 |
Not clear |
| Liping Yang, Honghui Guo, Yu Kuang, Hui Yang, Xi Zhang, Rong Tang, Dapeng Li, Li L. Neurotoxicity induced by combined exposure of microcystin-LR and nitrite in male zebrafish (Danio rerio): Effects of oxidant-antioxidant system and neurotransmitter system. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 253. 2021-12-06. PMID:34826614. |
the decreases in dopamine content, acetylcholinesterase activity and related gene mrna levels indicated that mc-lr and nitrite adversely affected the normal function of the dopaminergic and cholinergic systems in zebrafish brain. |
2021-12-06 |
2023-08-13 |
zebrafish |
| Anton Jm Loonen, Svetlana A Ivanov. Neurobiological mechanisms associated with antipsychotic drug-induced dystonia. Journal of psychopharmacology (Oxford, England). vol 35. issue 1. 2021-11-22. PMID:32900259. |
furthermore, striatal cholinergic interneurons have an important role to play in integrating cerebellar input with the output of cerebral cortex, and are also targeted by dopaminergic nigrostriatal fibres affecting dopamine d2 receptors. |
2021-11-22 |
2023-08-13 |
Not clear |
| Avery F McGuirt, Michael R Post, Irena Pigulevskiy, David Sulzer, Ori J Lieberma. Coordinated Postnatal Maturation of Striatal Cholinergic Interneurons and Dopamine Release Dynamics in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 16. 2021-11-19. PMID:33664134. |
coordinated postnatal maturation of striatal cholinergic interneurons and dopamine release dynamics in mice. |
2021-11-19 |
2023-08-13 |
mouse |
| Avery F McGuirt, Michael R Post, Irena Pigulevskiy, David Sulzer, Ori J Lieberma. Coordinated Postnatal Maturation of Striatal Cholinergic Interneurons and Dopamine Release Dynamics in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 16. 2021-11-19. PMID:33664134. |
its tonically active cholinergic interneuron (chi) is an integral regulator of the synaptic activity of other striatal neurons, as well as afferent axonal projections of midbrain dopamine (da) neurons; however, little is known about its development. |
2021-11-19 |
2023-08-13 |
mouse |
| Eduardo F Gallo, Julia Greenwald, Jenna Yeisley, Eric Teboul, Kelly M Martyniuk, Joseph M Villarin, Yulong Li, Jonathan A Javitch, Peter D Balsam, Christoph Kellendon. Dopamine D2 receptors modulate the cholinergic pause and inhibitory learning. Molecular psychiatry. 2021-11-18. PMID:34789847. |
dopamine d2 receptors modulate the cholinergic pause and inhibitory learning. |
2021-11-18 |
2023-08-13 |
Not clear |
| Anna Loftén, Louise Adermark, Mia Ericson, Bo Söderpal. An acetylcholine-dopamine interaction in the nucleus accumbens and its involvement in ethanol's dopamine-releasing effect. Addiction biology. vol 26. issue 3. 2021-11-01. PMID:32789970. |
cholinergic interneurons (cin) within the nucleus accumbens (nac) have been suggested to exert a regulatory impact on dopamine (da) neurotransmission locally, and defects in cin have been implied in several psychiatric disorders. |
2021-11-01 |
2023-08-13 |
rat |
| Angel Carvajal-Oliveros, Carmen Domínguez-Baleón, Rafaella V Zárate, Jorge M Campusano, Verónica Narváez-Padilla, Enrique Reynau. Nicotine suppresses Parkinson's disease like phenotypes induced by Synphilin-1 overexpression in Drosophila melanogaster by increasing tyrosine hydroxylase and dopamine levels. Scientific reports. vol 11. issue 1. 2021-10-22. PMID:33953275. |
nicotine is beneficial on fly survival and motility increasing tyrosine hydroxylase and dopamine levels, suggesting that cholinergic agonists may promote survival and metabolic function of the dopaminergic neurons that express sph-1. |
2021-10-22 |
2023-08-13 |
drosophila_melanogaster |
| N I Bohnen, C W Bogan, M L T M Mülle. Frontal and periventricular brain white matter lesions and cortical deafferentation of cholinergic and other neuromodulatory axonal projections. European neurological journal. vol 1. issue 1. 2021-10-21. PMID:22763426. |
a unique anatomic feature common to all cortical projections from subcortical neuromodulator systems (that not only include the cholinergic but also the monoaminergic systems, such as dopamine, serotonin, and norepinephrine) is that the proximal axons largely pass through the deep forebrain before fanning out to the cortex. |
2021-10-21 |
2023-08-12 |
Not clear |
| Myria Petrou, Vikas Kotagal, Nicolaas I Bohne. An update on brain imaging in parkinsonian dementia. Imaging in medicine. vol 4. issue 2. 2021-10-21. PMID:22768021. |
unlike severe loss of dopamine early in pd, extensive cholinergic losses have been consistently reported in pd with dementia. |
2021-10-21 |
2023-08-12 |
Not clear |
| Lauren Malave, Dustin R Zuelke, Santiago Uribe-Cano, Lev Starikov, Heike Rebholz, Eitan Friedman, Chuan Qin, Qin Li, Erwan Bezard, Andreas H Kottman. Dopaminergic co-transmission with sonic hedgehog inhibits abnormal involuntary movements in models of Parkinson's disease and L-Dopa induced dyskinesia. Communications biology. vol 4. issue 1. 2021-10-09. PMID:34552196. |
employing conditional genetic loss-of-function approaches, we show that reducing shh secretion from dopamine neurons or smoothened activity in cholinergic interneurons promotes lid. |
2021-10-09 |
2023-08-13 |
mouse |
| Anthony M Downs, Xueliang Fan, Radhika F Kadakia, Yuping Donsante, H A Jinnah, Ellen J Hes. Cell-intrinsic effects of TorsinA(ΔE) disrupt dopamine release in a mouse model of TOR1A dystonia. Neurobiology of disease. vol 155. 2021-10-02. PMID:33894367. |
although the mechanisms underlying the dystonic movements are largely unknown, abnormalities in striatal dopamine and acetylcholine neurotransmission are consistently implicated whereby dopamine release is reduced while cholinergic tone is increased. |
2021-10-02 |
2023-08-13 |
mouse |
| Anthony M Downs, Xueliang Fan, Radhika F Kadakia, Yuping Donsante, H A Jinnah, Ellen J Hes. Cell-intrinsic effects of TorsinA(ΔE) disrupt dopamine release in a mouse model of TOR1A dystonia. Neurobiology of disease. vol 155. 2021-10-02. PMID:33894367. |
because striatal cholinergic neurotransmission mediates dopamine release, it is not known if the dopamine release deficit is mediated indirectly by abnormal acetylcholine neurotransmission or if tor1a(Δe) acts directly within dopaminergic neurons to attenuate release. |
2021-10-02 |
2023-08-13 |
mouse |
| Anthony M Downs, Xueliang Fan, Radhika F Kadakia, Yuping Donsante, H A Jinnah, Ellen J Hes. Cell-intrinsic effects of TorsinA(ΔE) disrupt dopamine release in a mouse model of TOR1A dystonia. Neurobiology of disease. vol 155. 2021-10-02. PMID:33894367. |
to dissect the microcircuit that governs the deficit in dopamine release, we conditionally expressed tor1a(Δe) in either dopamine neurons or cholinergic interneurons in mice and assessed striatal dopamine release using ex vivo fast scan cyclic voltammetry or dopamine efflux using in vivo microdialysis. |
2021-10-02 |
2023-08-13 |
mouse |
| Anthony M Downs, Xueliang Fan, Radhika F Kadakia, Yuping Donsante, H A Jinnah, Ellen J Hes. Cell-intrinsic effects of TorsinA(ΔE) disrupt dopamine release in a mouse model of TOR1A dystonia. Neurobiology of disease. vol 155. 2021-10-02. PMID:33894367. |
conditional expression of tor1a(Δe) in cholinergic neurons did not affect striatal dopamine release. |
2021-10-02 |
2023-08-13 |
mouse |
| Alexander Hawlitschka, Charlotte Berg, Oliver Schmitt, Carsten Holzmann, Andreas Wree, Veronica Antipov. Repeated intrastriatal application of botulinum neurotoxin-A did not influence choline acetyltransferase-immunoreactive interneurons in hemiparkinsonian rat brain - A histological, stereological and correlational analysis. Brain research. vol 1742. 2021-09-14. PMID:32387181. |
in parkinson's disease, dopamine depletion leads to hyperactivity of cholinergic interneurons in the caudate-putamen (cpu). |
2021-09-14 |
2023-08-13 |
rat |
| Ersin Yavas, Andrew M J Youn. Repeated phencyclidine disrupts nicotinic acetylcholine regulation of dopamine release in nucleus accumbens: Implications for models of schizophrenia. Neurochemistry international. vol 140. 2021-09-02. PMID:32853750. |
accumbal cholinergic interneurons exert powerful modulatory control of local dopamine function, through nicotinic receptors located on dopamine terminals. |
2021-09-02 |
2023-08-13 |
rat |
| Ersin Yavas, Andrew M J Youn. Repeated phencyclidine disrupts nicotinic acetylcholine regulation of dopamine release in nucleus accumbens: Implications for models of schizophrenia. Neurochemistry international. vol 140. 2021-09-02. PMID:32853750. |
we investigated whether cholinergic regulation of stimulated dopamine release was disrupted by pretreatment with phencyclidine, a non-competitive nmda receptor antagonist, which provides a well validated animal model of schizophrenia. |
2021-09-02 |
2023-08-13 |
rat |