| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kholoud I Eissa, Mona M Kamel, Lamia W Mohamed, Asmaa E Kassa. Development of new Alzheimer's disease drug candidates using donepezil as a key model. Archiv der Pharmazie. 2022-09-23. PMID:36149034. |
it is a pathologically complicated, multifactorial disease characterized by β-amyloid precipitation, β-amyloid oligomer production, decrease in cholinergic function, and dysregulation of other neurotransmitter systems. |
2022-09-23 |
2023-08-14 |
Not clear |
| Ombretta Paladino, Arianna Moranda, Carla Falug. Spatiotemporal role of muscarinic signaling in early chick development: exposure to cholinomimetic agents by a mathematical model. Cell biology and toxicology. 2022-09-13. PMID:36098822. |
awareness is growing that, besides several neurotoxic effects, cholinomimetic drugs able to interfere the cholinergic neurotransmitter system may exert a teratogen effect in developing embryos of vertebrate and invertebrate organisms. |
2022-09-13 |
2023-08-14 |
chicken |
| Omkar N Athavale, Leo K Cheng, Alys R Clark, Recep Avci, Peng D. Mathematical Modeling of Gastric Slow Waves During Electrical Field Stimulation. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-10. PMID:36086185. |
a 21 % reduction in slow wave amplitude occurred when the cholinergic pathway was blocked, compared to a 46% reduction when no neurotransmitter pathways were blocked. |
2022-09-10 |
2023-08-14 |
Not clear |
| Saiko Okamoto, Mihoko Ishizawa, Satoki Inoue, Hideaki Sakuramot. Use of Automated Infrared Pupillometry to Predict Delirium in the Intensive Care Unit: A Prospective Observational Study. SAGE open nursing. vol 8. 2022-09-09. PMID:36081493. |
disturbances in the sympathetic neurons, including cholinergic neurons, have been reported to cause delirium by upsetting the balance of neurotransmitter synthesis, release, and inactivation. |
2022-09-09 |
2023-08-14 |
Not clear |
| Angeliki Zarkali, Andrea I Luppi, Emmanuel A Stamatakis, Suzanne Reeves, Peter McColgan, Louise-Ann Leyland, Andrew J Lees, Rimona S Wei. Changes in dynamic transitions between integrated and segregated states underlie visual hallucinations in Parkinson's disease. Communications biology. vol 5. issue 1. 2022-09-08. PMID:36075964. |
the regional energy needed for this transition was correlated with regional neurotransmitter density and gene expression for serotoninergic, gabaergic, noradrenergic and cholinergic, but not dopaminergic, receptors. |
2022-09-08 |
2023-08-14 |
Not clear |
| Elena E Vaiman, Natalia A Shnayder, Aiperi K Khasanova, Anna I Strelnik, Arseny J Gayduk, Mustafa Al-Zamil, Margarita R Sapronova, Natalia G Zhukova, Daria A Smirnova, Regina F Nasyrov. Pathophysiological Mechanisms of Antipsychotic-Induced Parkinsonism. Biomedicines. vol 10. issue 8. 2022-08-26. PMID:36009557. |
one of the causes of dip is the disruption of neurotransmitter interactions that regulate the signaling pathways of the dopaminergic, cholinergic, gabaergic, adenosinergic, endocannabinoid, and other neurotransmitter systems. |
2022-08-26 |
2023-08-14 |
Not clear |
| Yasir Hasan Siddique, Falaq Naz, Rahul, Himanshi Varshne. Comparative study of rivastigmine and galantamine on the transgenic Current research in pharmacology and drug discovery. vol 3. 2022-08-22. PMID:35992376. |
the accumulation of amyloid plaques and neurofibrillary tangles leads to the loss of neurons including the cholinergic neurons thus decreasing the levels of acetylcholine (a neurotransmitter). |
2022-08-22 |
2023-08-14 |
Not clear |
| Cyril Lhopitallier, Charlotte Perrault, Frédéric Chauveau, Françoise Saurini, Sylvie Berrard, Sylvie Granon, Alexis Faur. Characterization of social behavior in young and middle-aged ChAT-IRES-Cre mouse. PloS one. vol 17. issue 8. 2022-08-04. PMID:35925937. |
however, these data were obtained in mutant mice that also present alterations of several neurotransmitter systems, in addition to the cholinergic system. |
2022-08-04 |
2023-08-14 |
mouse |
| Correction to: Cholinergic neurotransmitter system: a potential marker for post-stroke cognitive recovery. Brain : a journal of neurology. 2022-08-02. PMID:35918789. |
correction to: cholinergic neurotransmitter system: a potential marker for post-stroke cognitive recovery. |
2022-08-02 |
2023-08-14 |
Not clear |
| Wenchao Li, Chun Zhang, Yang Yang Wang, Lifei Xiao, Yan Feng, Xianhao Huo, Chaofan Wang, Yu Sun, Feng Wang, Tao Su. Alterations of RNAs in the insula related to cocaine-induced condition place preference in adolescent mice. Biochemical and biophysical research communications. vol 621. 2022-07-12. PMID:35820280. |
a total of 198 differentially expressed genes (deg) that functioned in synaptic transmission, cholinergic, developmental process, neurotransmitter metabolic process, drug catabolism, cellular response to drug, map kinase activity, ceramidase activity, and drug resistance were significantly enriched. |
2022-07-12 |
2023-08-14 |
mouse |
| Tomasz Tuzimski, Anna Petruczyni. Determination of Anti-Alzheimer's Disease Activity of Selected Plant Ingredients. Molecules (Basel, Switzerland). vol 27. issue 10. 2022-05-28. PMID:35630702. |
one of the most important therapeutic strategies is controlling the level of acetylcholine-a neurotransmitter in cholinergic synapses-by blocking the degradation of acetylcholine using acetylcholinesterase inhibitors such as tacrine, galantamine, donepezil and rivastigmine. |
2022-05-28 |
2023-08-13 |
Not clear |
| Isaac Oluwatobi Akefe, Victoria Aderonke Adegoke, Ibrahim Yusuf Lamidi, Matthew Phillip Ameh, Enokela Shaibu Idoga, Simon Azubuike Ubah, Itopa Etudaye Ajay. Myrtenal mitigates streptozotocin-induced spatial memory deficit via improving oxido inflammatory, cholinergic and neurotransmitter functions in mice. Current research in pharmacology and drug discovery. vol 3. 2022-05-16. PMID:35570857. |
myrtenal mitigates streptozotocin-induced spatial memory deficit via improving oxido inflammatory, cholinergic and neurotransmitter functions in mice. |
2022-05-16 |
2023-08-13 |
mouse |
| Isaac Oluwatobi Akefe, Victoria Aderonke Adegoke, Ibrahim Yusuf Lamidi, Matthew Phillip Ameh, Enokela Shaibu Idoga, Simon Azubuike Ubah, Itopa Etudaye Ajay. Myrtenal mitigates streptozotocin-induced spatial memory deficit via improving oxido inflammatory, cholinergic and neurotransmitter functions in mice. Current research in pharmacology and drug discovery. vol 3. 2022-05-16. PMID:35570857. |
data from this study demonstrated that the administration of streptozotocin (stz) impaired spatial memory and induced alterations in markers of oxido-inflammatory response, cholinergic function, cytoarchitecture, and neurotransmitter levels in mice hippocampus. |
2022-05-16 |
2023-08-13 |
mouse |
| Sarah Könemann, Melissa von Wyl, Colette Vom Ber. Zebrafish Larvae Rapidly Recover from Locomotor Effects and Neuromuscular Alterations Induced by Cholinergic Insecticides. Environmental science & technology. 2022-05-16. PMID:35575681. |
owing to the importance of acetylcholine as a neurotransmitter, many insecticides target the cholinergic system. |
2022-05-16 |
2023-08-13 |
zebrafish |
| Karoline Martins Dos Santos Larangeira, Davi José de Almeida Moraes, Melina Pires da Silva, Vagner Roberto Antune. Exercise Training and Chemogenetic Activation of the Dorsal Motor Nucleus of the Vagus Rescue the Changes in the Hepatic Vein Glucose Concentration by Central Action of Insulin in SHR. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554371. |
here we aimed to investigate whether the deficiency of central action of insulin to control the hvgc of shr is due to a dysfunction in the cholinergic neurotransmission in the dmnv and which putative neurotransmitter could play a role in this circuitry. |
2022-05-13 |
2023-08-13 |
rat |
| Fatemeh Geranmaye. Cholinergic neurotransmitter system: a potential marker for post-stroke cognitive recovery. Brain : a journal of neurology. 2022-04-19. PMID:35438715. |
cholinergic neurotransmitter system: a potential marker for post-stroke cognitive recovery. |
2022-04-19 |
2023-08-13 |
Not clear |
| Shefali Chaudhary, Simon Zhornitsky, Herta H Chao, Christopher H van Dyck, Chiang-Shan R L. Emotion Processing Dysfunction in Alzheimer's Disease: An Overview of Behavioral Findings, Systems Neural Correlates, and Underlying Neural Biology. American journal of Alzheimer's disease and other dementias. vol 37. 2022-03-31. PMID:35357236. |
finally, the reviewed studies implicating major neurotransmitter systems in anxiety and depression in ad supported altered cholinergic and noradrenergic signaling in ad emotional disorders. |
2022-03-31 |
2023-08-13 |
Not clear |
| Maia A Burjanadze, Manana G Dashniani, Revaz O Solomonia, Gela V Beselia, Lia Tsverava, Vincenzo Lagani, Nino C Chkhikvishvili, Temur L Naneishvili, Lali B Kruashvili, Mariam R Chighladz. Age-related changes in medial septal cholinergic and GABAergic projection neurons and hippocampal neurotransmitter receptors: relationship with memory impairment. Experimental brain research. 2022-03-31. PMID:35357523. |
age-related changes in medial septal cholinergic and gabaergic projection neurons and hippocampal neurotransmitter receptors: relationship with memory impairment. |
2022-03-31 |
2023-08-13 |
rat |
| Ying Xia, Eamonn Eeles, Jurgen Fripp, Donna Pinsker, Paul Thomas, Melissa Latter, Vincent Doré, Amir Fazlollahi, Pierrick Bourgeat, Victor L Villemagne, Elizabeth J Coulson, Stephen Ros. Reduced cortical cholinergic innervation measured using [ NeuroImage. Clinical. vol 34. 2022-03-28. PMID:35344804. |
reduced cortical cholinergic innervation measured using [ dysfunction of the cholinergic basal forebrain (bf) neurotransmitter system, including cholinergic axon denervation of the cortex, plays an important role in cognitive decline and dementia. |
2022-03-28 |
2023-08-13 |
Not clear |
| Zhi-Ru Chen, Jia-Bao Huang, Shu-Long Yang, Fen-Fang Hon. Role of Cholinergic Signaling in Alzheimer's Disease. Molecules (Basel, Switzerland). vol 27. issue 6. 2022-03-26. PMID:35335180. |
acetylcholine, a neurotransmitter secreted by cholinergic neurons, is involved in signal transduction related to memory and learning ability. |
2022-03-26 |
2023-08-13 |
Not clear |