| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Kopańska, Anna Łagowska, Barbara Kuduk, Agnieszka Banaś-Ząbczy. Acrylamide Neurotoxicity as a Possible Factor Responsible for Inflammation in the Cholinergic Nervous System. International journal of molecular sciences. vol 23. issue 4. 2022-02-26. PMID:35216144. |
within the cholinergic system, there are cholinergic neurons, anatomical cholinergic structures, the neurotransmitter acetylcholine (ach) and cholinergic receptors. |
2022-02-26 |
2023-08-13 |
Not clear |
| Marta Kopańska, Anna Łagowska, Barbara Kuduk, Agnieszka Banaś-Ząbczy. Acrylamide Neurotoxicity as a Possible Factor Responsible for Inflammation in the Cholinergic Nervous System. International journal of molecular sciences. vol 23. issue 4. 2022-02-26. PMID:35216144. |
the cellular molecular mechanism for inhibiting cytokine synthesis is attributed to acetylcholine (ach), the major vagal neurotransmitter, and the α7 nicotinic receptor (α7nachr) subunit is a key receptor for the cholinergic anti-inflammatory pathway. |
2022-02-26 |
2023-08-13 |
Not clear |
| David L Sultzer, Aaron C Lim, Hailey L Gordon, Brandon C Yarns, Rebecca J Melros. Cholinergic receptor binding in unimpaired older adults, mild cognitive impairment, and Alzheimer's disease dementia. Alzheimer's research & therapy. vol 14. issue 1. 2022-02-08. PMID:35130968. |
cholinergic neurotransmitter system dysfunction contributes to cognitive impairment in alzheimer's disease and other syndromes. |
2022-02-08 |
2023-08-13 |
Not clear |
| Christian Fillafer, Yana S Koll, Matthias F Schneide. Lipid Membrane State Change by Catalytic Protonation and the Implications for Synaptic Transmission. Membranes. vol 12. issue 1. 2022-01-21. PMID:35054529. |
in cholinergic synapses, the neurotransmitter acetylcholine (ach) is rapidly hydrolyzed by esterases to choline and acetic acid (ah). |
2022-01-21 |
2023-08-13 |
Not clear |
| Ana Sofía Vallés, Francisco J Barrante. Dendritic spine membrane proteome and its alterations in autistic spectrum disorder. Advances in protein chemistry and structural biology. vol 128. 2022-01-17. PMID:35034726. |
since cholinergic neurotransmission participates in the regulation of cognitive function (attention, memory, learning processes, cognitive flexibility, social interactions) brain acetylcholine receptors are likely to play an important role in the dysfunctional synapses in asd, either directly or indirectly via the modulatory functions exerted on other neurotransmitter receptor proteins and spine-resident proteins. |
2022-01-17 |
2023-08-13 |
Not clear |
| Ayland C Letsinger, Zhenglin Gu, Jerrel L Yake. α7 nicotinic acetylcholine receptors in the hippocampal circuit: taming complexity. Trends in neurosciences. 2021-12-17. PMID:34916082. |
cholinergic innervation of the hippocampus uses the neurotransmitter acetylcholine (ach) to coordinate neuronal circuit activity while simultaneously influencing the function of non-neuronal cell types. |
2021-12-17 |
2023-08-13 |
Not clear |
| Hong-Bo Zhao, Li-Man Liu, Ning Yu, Yan Zhu, Ling Mei, Jin Chen, Chun Lian. Efferent neurons control hearing sensitivity and protect hearing from noise through the regulation of gap junctions between cochlear supporting cells. Journal of neurophysiology. 2021-12-15. PMID:34907797. |
moc nerve fibers are cholinergic and acetylcholine (ach) is a primary neurotransmitter. |
2021-12-15 |
2023-08-13 |
Not clear |
| Stefano Loizzo, Roberto Rimondini, Gabriele Campana, Andrea Fortuna, Zaira Maroccia, Alessandro Martorana, Giacomo Koc. C57BL/6J and DBA/2J strains present opposite sex differences in flash visual evoked potential latency: A possible confusing factor in gender studies on neurological diseases' transgenic models. Brain research bulletin. vol 176. 2021-12-10. PMID:34391824. |
the cholinergic neurotransmitter system in the brain is crucial in processing information related to cognitive, behavioral, and motor functions. |
2021-12-10 |
2023-08-13 |
mouse |
| b' K Szmicsekov\\xc3\\xa1, L Bies Piv\\xc3\\xa1\\xc4\\x8dkov\\xc3\\xa1, Z Kili\\xc3\\xa1nov\\xc3\\xa1, \\xc4\\xbd Slobodov\\xc3\\xa1, P K\\xc5\\x99enek, A Hrabovsk\\xc3\\xa. Aortic butyrylcholinesterase is reduced in spontaneously hypertensive rats. Physiological research. vol 70. issue 5. 2021-12-09. PMID:34505519.' |
despite the fact that vessels have sparse cholinergic innervation, acetylcholine (ach), the primary neurotransmitter of parasympathetic nervous system, has been commonly used in physiological experiments to assess vascular function. |
2021-12-09 |
2023-08-13 |
rat |
| Aren van Waarde, Sofia Marcolini, Peter Paul de Deyn, Rudi A J O Dierck. PET Agents in Dementia: An Overview. Seminars in nuclear medicine. vol 51. issue 3. 2021-12-02. PMID:33500121. |
classified by the target which the agents visualize, seven groups of tracers can be distinguished, namely radiopharmaceuticals for: (1) misfolded proteins (ß-amyloid, tau, α-synuclein), (2) neuroinflammation (overexpression of translocator protein), (3) elements of the cholinergic system, (4) elements of monoamine neurotransmitter systems, (5) synaptic density, (6) cerebral energy metabolism (glucose transport/ hexokinase), and (7) various other proteins. |
2021-12-02 |
2023-08-13 |
Not clear |
| Xuan Gu, Xiaoying Wan. An overview of recent analysis and detection of acetylcholine. Analytical biochemistry. vol 632. 2021-12-01. PMID:34534543. |
acetylcholine (ach), the major neurotransmitter secreted by cholinergic neurons, is widely found in the peripheral and central nervous systems, and its main function is to complete the transmission of neural signals. |
2021-12-01 |
2023-08-13 |
Not clear |
| Ruiqing N. Positron Emission Tomography in Animal Models of Alzheimer's Disease Amyloidosis: Translational Implications. Pharmaceuticals (Basel, Switzerland). vol 14. issue 11. 2021-11-30. PMID:34832961. |
in this review, we focus on recent positron emission tomography studies of cerebral amyloid-beta accumulation, hypoglucose metabolism, synaptic and neurotransmitter receptor deficits (cholinergic and glutamatergic system), blood-brain barrier impairment, and neuroinflammation (microgliosis and astrocytosis) in animal models of alzheimer's disease amyloidosis. |
2021-11-30 |
2023-08-13 |
Not clear |
| Jiaqi Lv, Xiaoxiao Ji, Zhen Li, Huiqin Ha. The role of the cholinergic anti-inflammatory pathway in autoimmune rheumatic diseases. Scandinavian journal of immunology. vol 94. issue 4. 2021-11-25. PMID:34780075. |
the cholinergic anti-inflammatory pathway (cap) is a classic neuroimmune pathway, consisting of the vagus nerve, acetylcholine (ach)-the pivotal neurotransmitter of the vagus nerve-and its receptors. |
2021-11-25 |
2023-08-13 |
Not clear |
| Tun-Wei Hsu, Jong-Ling Fuh, Da-Wei Wang, Li-Fen Chen, Chia-Jung Chang, Wen-Sheng Huang, Hsiu-Mei Wu, Wan-Yuo Gu. Disrupted metabolic connectivity in dopaminergic and cholinergic networks at different stages of dementia from Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33686089. |
disrupted metabolic connectivity in dopaminergic and cholinergic networks at different stages of dementia from dementia is related to the cellular accumulation of β-amyloid plaques, tau aggregates, or α-synuclein aggregates, or to neurotransmitter deficiencies in the dopaminergic and cholinergic pathways. |
2021-11-22 |
2023-08-13 |
human |
| Sina Marzoughi, Ankur Banerjee, Catherine R Jutzeler, Marco A M Prado, Jan Rosner, Jacquelyn J Cragg, Neil Cashma. Tardive neurotoxicity of anticholinergic drugs: A review. Journal of neurochemistry. vol 158. issue 6. 2021-11-17. PMID:33222198. |
the cholinergic system is a complex neurotransmitter system with functional involvement at multiple levels of the nervous system including the cerebral cortex, spinal cord, autonomic nervous system, and neuromuscular junction. |
2021-11-17 |
2023-08-13 |
human |
| Rosana Banzato, Nathalia M Pinheiro, Clarice R Olivo, Fernanda R Santana, Fernanda D T Q S Lopes, Luciana C Caperuto, Niels O Câmara, Milton A Martins, Iolanda F L C Tibério, Marco Antônio M Prado, Vânia F Prado, Carla M Prad. Long-term endogenous acetylcholine deficiency potentiates pulmonary inflammation in a murine model of elastase-induced emphysema. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:34354132. |
acetylcholine (ach), the neurotransmitter of the cholinergic system, regulates inflammation in several diseases including pulmonary diseases. |
2021-11-15 |
2023-08-13 |
mouse |
| Jiyeon Han, Zhi Du, Mi Hee Li. Mechanistic Insight into the Design of Chemical Tools to Control Multiple Pathogenic Features in Alzheimer's Disease. Accounts of chemical research. vol 54. issue 20. 2021-11-10. PMID:34606227. |
finally, the loss of cholinergic transmission mediated by the neurotransmitter acetylcholine (ach) contributes to cognitive deficits observed in ad.in this account, we illustrate the design principles for small-molecule-based chemical tools with reactivities against metal-free aβ, metal-bound aβ, ros, and ache. |
2021-11-10 |
2023-08-13 |
Not clear |
| Cecilia Flores-Clemente, María Inés Nicolás-Vázquez, Elvia Mera Jiménez, Maricarmen Hernández-Rodrígue. Inhibition of Astrocytic Histamine Biomolecules. vol 11. issue 10. 2021-11-08. PMID:34680041. |
changes in neurotransmitter systems in patients with ad, including cholinergic, gabaergic, serotoninergic, noradrenergic, and histaminergic changes have been reported. |
2021-11-08 |
2023-08-13 |
Not clear |
| Yoshihiko Kakinum. Significance of vagus nerve function in terms of pathogenesis of psychosocial disorders. Neurochemistry international. vol 143. 2021-11-04. PMID:33307153. |
the neurotransmitter acetylcholine, released from the cholinergic system including vn, has been known to play an anti-inflammatory role through the efferent pathways in regulating peripheral inflammatory responses profoundly involved in the pathogenesis of diseases. |
2021-11-04 |
2023-08-13 |
Not clear |
| Trevor Archer, Marlene Oscar-Berman, Kenneth Blum, Mark Gol. Neurogenetics and Epigenetics in Impulsive Behaviour: Impact on Reward Circuitry. Journal of genetic syndromes & gene therapy. vol 3. issue 3. 2021-10-21. PMID:23264884. |
brain-derived neurotrophic factor (bdnf) affects the development and integrity of the noradrenergic, dopaminergic, serotonergic, glutamatergic, and cholinergic neurotransmitter systems, and plasma levels of the neurotrophin are associated with both cognitive and aggressive impulsiveness. |
2021-10-21 |
2023-08-12 |
Not clear |