| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C B Little, A Barai, D Burkhardt, S M Smith, A J Fosang, Z Werb, M Shah, E W Thompso. Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. Arthritis and rheumatism. vol 60. issue 12. 2010-02-18. PMID:19950295. |
matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. |
2010-02-18 |
2023-08-12 |
mouse |
| Massoud Seifi, Arezoo Maghzi, Norbert Gutknecht, Maziar Mir, Mohammad Asna-Ashar. The effect of 904 nm low level laser on condylar growth in rats. Lasers in medical science. vol 25. issue 1. 2010-02-05. PMID:19238504. |
proliferation of prechondroblasts, followed by synthesis of the extracellular matrix and hypertrophy of the cartilage cells, governs the major part of condylar growth. |
2010-02-05 |
2023-08-12 |
rat |
| Ezequiel J Molina, Jon Palma, Dipin Gupta, John P Gaughan, Steven Houser, Mahender Mach. Right ventricular effects of intracoronary delivery of mesenchymal stem cells (MSC) in an animal model of pressure overload heart failure. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 63. issue 10. 2010-02-03. PMID:18993028. |
in a rat model of left ventricular pressure overload hypertrophy with biventricular failure, we studied the effects of intracoronary delivery of mesenchymal stem cells (mcs) upon right ventricular hemodynamic performance, profiles of local inflammation and apoptosis, and determinants of extracellular matrix remodeling. |
2010-02-03 |
2023-08-12 |
rat |
| Ezequiel J Molina, Jon Palma, Dipin Gupta, John P Gaughan, Steven Houser, Mahender Mach. Right ventricular effects of intracoronary delivery of mesenchymal stem cells (MSC) in an animal model of pressure overload heart failure. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 63. issue 10. 2010-02-03. PMID:18993028. |
in this model of left ventricular pressure overload hypertrophy and biventricular failure, intracoronary delivery of msc was associated with an improvement in the right ventricular hemodynamic performance, profiles of local inflammation and apoptosis, and determinants of extracellular matrix remodeling. |
2010-02-03 |
2023-08-12 |
rat |
| Guang-Qing Wang, Zhao-Fan Xi. Transplantation of epidermis of scar tissue on acellular dermal matrix. Burns : journal of the International Society for Burn Injuries. vol 35. issue 3. 2010-02-02. PMID:18951705. |
this study enrolled 22 participants with hypertrophic scarring after burn who received treatment with co-transplantation of acellular dermal matrix and epidermis of either normal skin or scar tissue. |
2010-02-02 |
2023-08-12 |
human |
| Guang-Qing Wang, Zhao-Fan Xi. Transplantation of epidermis of scar tissue on acellular dermal matrix. Burns : journal of the International Society for Burn Injuries. vol 35. issue 3. 2010-02-02. PMID:18951705. |
however, if co-transplanted on acellular dermal matrix, this effectively inhibited scar formation and pruritus, providing an alternative method to treat hypertrophic scarring. |
2010-02-02 |
2023-08-12 |
human |
| Youli Wang, Kathleen O Heilig, Andrew W Minto, Shenglin Chen, Minghui Xiang, David A Dean, Richard C Geiger, Anthony Chang, Dimitrina D Pravtcheva, Martin Schlimme, Dilip K Deb, Ying Wang, Charles W Heili. Nephron-deficient Fvb mice develop rapidly progressive renal failure and heavy albuminuria involving excess glomerular GLUT1 and VEGF. Laboratory investigation; a journal of technical methods and pathology. vol 90. issue 1. 2010-02-02. PMID:19918242. |
the fvbrop os/+ mice (fvb background) exhibited increased glomerular glut1, glucose uptake, vegf, glomerular hypertrophy, hyperfiltration, extensive podocyte foot process effacement, marked albuminuria, severe extracellular matrix (ecm) protein deposition, and rapidly progressive renal failure leading to their early demise. |
2010-02-02 |
2023-08-12 |
mouse |
| b' Erja Mustonen, Virva Pohjolainen, Jani Aro, Sampsa Pikkarainen, Hanna Leskinen, Heikki Ruskoaho, Jaana Rys\\xc3\\xa. Upregulation of cardiac matrix Gla protein expression in response to hypertrophic stimuli. Blood pressure. vol 18. issue 5. 2010-01-26. PMID:19919401.' |
upregulation of cardiac matrix gla protein expression in response to hypertrophic stimuli. |
2010-01-26 |
2023-08-12 |
rat |
| b' Erja Mustonen, Virva Pohjolainen, Jani Aro, Sampsa Pikkarainen, Hanna Leskinen, Heikki Ruskoaho, Jaana Rys\\xc3\\xa. Upregulation of cardiac matrix Gla protein expression in response to hypertrophic stimuli. Blood pressure. vol 18. issue 5. 2010-01-26. PMID:19919401.' |
matrix gla protein (mgp) expression is increased in cardiac hypertrophy, but the precise mechanisms regulating its expression are unknown. |
2010-01-26 |
2023-08-12 |
rat |
| Ashwin Akki, Min Zhang, Colin Murdoch, Alison Brewer, Ajay M Sha. NADPH oxidase signaling and cardiac myocyte function. Journal of molecular and cellular cardiology. vol 47. issue 1. 2010-01-06. PMID:19374908. |
of the five known nadph oxidase isoforms, several are expressed in cardiovascular cells where they are involved in physiological and pathological processes such as the regulation of vascular tone, cell growth, migration, proliferation, hypertrophy, apoptosis and matrix deposition. |
2010-01-06 |
2023-08-12 |
Not clear |
| Luigi Rossiello, Francesco D'Andrea, Roberto Grella, Giuseppe Signoriello, Ciro Abbondanza, Caterina De Rosa, Mariaevelina Prudente, Marianna Morlando, Raffaele Rossiell. Differential expression of cyclooxygenases in hypertrophic scar and keloid tissues. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 17. issue 5. 2009-12-23. PMID:19769727. |
hypertrophic scar (hs) and keloid (kl) are two forms of an abnormal cutaneous scarring process, mainly characterized by excessive extracellular matrix deposition and fibroblast proliferation. |
2009-12-23 |
2023-08-12 |
human |
| Martina Vokurkova, Shaoping Xu, Rhian M Touy. Reactive oxygen species, cell growth, cell cycle progression and vascular remodeling in hypertension. Future cardiology. vol 3. issue 1. 2009-12-14. PMID:19804207. |
oxidative stress causes vascular injury by reducing nitric oxide bioavailability, altering endothelial function and vascular contraction/dilation, promoting vascular smooth muscle cell proliferation and hypertrophy, and increasing extracellular matrix deposition and inflammation. |
2009-12-14 |
2023-08-12 |
Not clear |
| Guo-You Zhang, Tao Cheng, Ming-Hua Zheng, Cheng-Gang Yi, Hua Pan, Zhi-Jie Li, Xing-Long Chen, Qing Yu, Liang-Fu Jiang, Fei-Ya Zhou, Xiao-Yang Li, Jing-Quan Yang, Ting-Gang Chu, Wei-Yang Ga. Activation of peroxisome proliferator-activated receptor-gamma inhibits transforming growth factor-beta1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro. Archives of dermatological research. vol 301. issue 7. 2009-12-11. PMID:19466435. |
activation of peroxisome proliferator-activated receptor-gamma inhibits transforming growth factor-beta1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro. |
2009-12-11 |
2023-08-12 |
Not clear |
| Guo-You Zhang, Tao Cheng, Ming-Hua Zheng, Cheng-Gang Yi, Hua Pan, Zhi-Jie Li, Xing-Long Chen, Qing Yu, Liang-Fu Jiang, Fei-Ya Zhou, Xiao-Yang Li, Jing-Quan Yang, Ting-Gang Chu, Wei-Yang Ga. Activation of peroxisome proliferator-activated receptor-gamma inhibits transforming growth factor-beta1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro. Archives of dermatological research. vol 301. issue 7. 2009-12-11. PMID:19466435. |
however, their effects on extracellular matrix (ecm) turnover in hypertrophic scar fibroblasts (hsfs), and the related molecular mechanisms are unknown. |
2009-12-11 |
2023-08-12 |
Not clear |
| Allam Appa Rao, Hanuman Thota, Ramamurthy Adapala, Suresh Babu Changalasetty, Ramachandra Sridhar Gumpeny, Annapurna Akula, Lalitha Saroja Thota, Siva Reddy Challa, M R Narasinga Rao, Undurti N Da. Proteomic analysis in diabetic cardiomyopathy using bioinformatics approach. Bioinformatics and biology insights. vol 2. 2009-12-11. PMID:19812762. |
abnormalities in diabetic cardiomyopathy include: myocardial hypertrophy, impairment of contractile proteins, accumulation of extracellular matrix proteins, formation of advanced glycation end products, and decreased left ventricular compliance. |
2009-12-11 |
2023-08-12 |
Not clear |
| R A Kagan, M Kinsel, K Gloor, N D Mylniczenko, J N Langan, L L Farina, K A Teri. Morphologic evidence suggestive of hypertension in western gray kangaroos (Macropus fuliginosus). Veterinary pathology. vol 46. issue 5. 2009-12-02. PMID:19429991. |
relevant lesions included increased thickness of the renal arteriolar tunica media with smooth muscle hypertrophy and/or hyperplasia, accumulation of extracellular matrix within arterioles, increased vascular tortuosity, and varying degrees of juxtaglomerular hyperplasia. |
2009-12-02 |
2023-08-12 |
Not clear |
| Atsushi Saito, Shin-ichiro Hino, Tomohiko Murakami, Soshi Kanemoto, Shinichi Kondo, Masahiro Saitoh, Riko Nishimura, Toshiyuki Yoneda, Tatsuya Furuichi, Shiro Ikegawa, Masahito Ikawa, Masaru Okabe, Kazunori Imaizum. Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nature cell biology. vol 11. issue 10. 2009-11-17. PMID:19767744. |
the cartilage showed a lack of typical columnar structure in the proliferating zone and a decrease in the size of the hypertrophic zone, resulting in a significant reduction of extracellular matrix proteins. |
2009-11-17 |
2023-08-12 |
mouse |
| Nelson Elias, Flávio Tarasoutchi, Guilherme Sobreira Spina, Roney O Sampaio, Pablo M A Pomerantzeff, Francisco Rafael Laurindo, Max Grinber. Myocardial fibrosis and ventricular remodeling in severe chronic aortic regurgitation. Arquivos brasileiros de cardiologia. vol 92. issue 1. 2009-11-12. PMID:19219266. |
significant symptomatic chronic aortic regurgitation (ar) leads to considerable left ventricular remodeling at the expense of myocyte hypertrophy and extracellular matrix remodeling. |
2009-11-12 |
2023-08-12 |
Not clear |
| Takashi Yamada, Kohzo Nagata, Xian Wu Cheng, Koji Obata, Masako Saka, Masaaki Miyachi, Keiko Naruse, Takao Nishizawa, Akiko Noda, Hideo Izawa, Masafumi Kuzuya, Kenji Okumura, Toyoaki Murohara, Mitsuhiro Yokot. Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats. European journal of pharmacology. vol 615. issue 1-3. 2009-11-10. PMID:19501083. |
marked left ventricular hypertrophy and fibrosis were apparent and the ratio of collagen type i to type iii mrna levels and the activity of matrix metalloproteinase (mmp)-2 and its mrna expression in the myocardium were increased in vehicle at 19 weeks in comparison with control. |
2009-11-10 |
2023-08-12 |
rat |
| Erin E Yund, Joseph A Hill, Rebecca S Kelle. Hic-5 is required for fetal gene expression and cytoskeletal organization of neonatal cardiac myocytes. Journal of molecular and cellular cardiology. vol 47. issue 4. 2009-11-04. PMID:19540241. |
cardiac costameres link the extracellular matrix to the sarcomere at the z-disc and contain proteins such as integrins and other signaling molecules implicated in the regulation of pathological hypertrophy. |
2009-11-04 |
2023-08-12 |
Not clear |