| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David S Ruff, Ilaria Balbo, Ruo-Yah Lai, Diarra Dieng, Charlotte Hennessey, Krish Vennam, Andrew J Dwork, Morgan McCreary, Elan D Louis, Phyllis L Faust, Sheng-Han Ku. Reduced Bergmann glial process terminations and lateral appendages in essential tremor. Annals of clinical and translational neurology. 2023-12-15. PMID:38098226. |
among their many roles, bergmann glia in the cerebellar cortex ensheath purkinje cell synapses and provide neuroprotection. |
2023-12-15 |
2023-12-17 |
Not clear |
| Anton N Shuvaev, Olga S Belozor, Oleg Mozhei, Dariya A Yakovleva, Ilya V Potapenko, Andrey N Shuvaev, Marina V Smolnikova, Vladimir V Salmin, Alla B Salmina, Hirokazu Hirai, Anja G Teschemacher, Sergey Kasparo. Chronic optogenetic stimulation of Bergman glia leads to dysfunction of EAAT1 and Purkinje cell death, mimicking the events caused by expression of pathogenic ataxin-1. Neurobiology of disease. vol 154. 2021-09-02. PMID:33753288. |
chronic optogenetic stimulation of bergman glia leads to dysfunction of eaat1 and purkinje cell death, mimicking the events caused by expression of pathogenic ataxin-1. |
2021-09-02 |
2023-08-13 |
mouse |
| Anton N Shuvaev, Olga S Belozor, Oleg I Mozhei, Elena D Khilazheva, Andrey N Shuvaev, Yana V Fritsler, S Kasparo. Protective Effect of Memantine on Bergmann Glia and Purkinje Cells Morphology in Optogenetic Model of Neurodegeneration in Mice. International journal of molecular sciences. vol 22. issue 15. 2021-08-16. PMID:34360588. |
here we induced reactive transformation of cerebellar bergmann glia (bg) using this novel optogenetic approach and tested whether memantine could counteract changes in bg and purkinje cell (pc) morphology and expression of the main glial glutamate transporter-excitatory amino acid transporter 1 (eaat1). |
2021-08-16 |
2023-08-13 |
mouse |
| David E Buchholz, Thomas S Carroll, Arif Kocabas, Xiaodong Zhu, Hourinaz Behesti, Phyllis L Faust, Lauren Stalbow, Yin Fang, Mary E Hatte. Novel genetic features of human and mouse Purkinje cell differentiation defined by comparative transcriptomics. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 26. 2020-09-30. PMID:32546527. |
to analyze human purkinje cell (pc) differentiation, we optimized a protocol to generate human pluripotent stem cell-derived purkinje cells (hpsc-pcs) that formed synapses when cultured with mouse cerebellar glia and granule cells and fired large calcium currents, measured with the genetically encoded calcium indicator jrgeco1a. |
2020-09-30 |
2023-08-13 |
mouse |
| Yumi Sato, Akira Sato, Shota Mizuno, Jun-Na Hirota, Shuhei Fujima, Chiaki Ishii, Yoshitake Sano, Teiichi Furuich. Comparative gene expression analysis of the engulfment and cell motility (ELMO) protein family in the mouse brain. Gene expression patterns : GEP. vol 34. 2020-04-23. PMID:31521773. |
in the purkinje cell layer, elmo1 and elmo2 were expressed in purkinje cells and bergmann glia, respectively. |
2020-04-23 |
2023-08-13 |
mouse |
| Saori Kikuchihara, Shouta Sugio, Kenji F Tanaka, Takaki Watanabe, Masanobu Kano, Yoshihiko Yamazaki, Masahiko Watanabe, Kazuhiro Ikenak. Ectopic positioning of Bergmann glia and impaired cerebellar wiring in Mlc1-over-expressing mice. Journal of neurochemistry. vol 147. issue 3. 2019-09-27. PMID:29920672. |
here, we examined the cerebellum of mlc1-over-expressing mouse and found that the distribution of bergmann glia (bg) was normally compacted along the purkinje cell (pc) layer until postnatal day 10 (p10), while most bg were dispersed throughout the molecular layer by p28. |
2019-09-27 |
2023-08-13 |
mouse |
| Géraldine Sicot, Laurent Servais, Diana M Dinca, Axelle Leroy, Cynthia Prigogine, Fadia Medja, Sandra O Braz, Aline Huguet-Lachon, Cerina Chhuon, Annie Nicole, Noëmy Gueriba, Ruan Oliveira, Bernard Dan, Denis Furling, Maurice S Swanson, Ida Chiara Guerrera, Guy Cheron, Geneviève Gourdon, Mário Gomes-Pereir. Downregulation of the Glial GLT1 Glutamate Transporter and Purkinje Cell Dysfunction in a Mouse Model of Myotonic Dystrophy. Cell reports. vol 19. issue 13. 2018-04-20. PMID:28658620. |
we found pronounced rna toxicity in the bergmann glia of the cerebellum, in association with abnormal purkinje cell firing and fine motor incoordination in dm1 mice. |
2018-04-20 |
2023-08-13 |
mouse |
| O J Castejó. Ultrastructural pathology of human peritumoural oedematous cerebellar cortex. Folia neuropathologica. vol 54. issue 2. 2017-04-13. PMID:27543770. |
swollen and clear bergmann glial cell cytoplasm was observed closely applied to the oedematous clear and dark purkinje cell body, dendritic trunk, secondary and tertiary dendritic branches. |
2017-04-13 |
2023-08-13 |
human |
| Chiara Di Pietro, Daniela Marazziti, Gina La Sala, Zeinab Abbaszadeh, Elisabetta Golini, Rafaele Matteoni, Glauco P Tocchini-Valentin. Primary Cilia in the Murine Cerebellum and in Mutant Models of Medulloblastoma. Cellular and molecular neurobiology. vol 37. issue 1. 2017-02-13. PMID:26935062. |
the mammalian g-protein-coupled receptor 37-like 1 is specifically expressed in cerebellar bergmann glia astrocytes and participates in regulating postnatal cerebellar granule neuron proliferation/differentiation and bergmann glia and purkinje neuron maturation. |
2017-02-13 |
2023-08-13 |
mouse |
| Jerry Vriend, Saeid Ghavami, Hassan Marzba. The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma. Molecular brain. vol 8. issue 1. 2016-07-06. PMID:26475605. |
postnatally, granule cells migrate from the external germinal zone radially through the purkinje cell layer, guided by bergmann glia fibers, to the internal granular cell layer.medulloblastomas (mbs) are the most common malignant childhood brain tumor. |
2016-07-06 |
2023-08-13 |
Not clear |
| Florian Meier, Florian Giesert, Sabit Delic, Theresa Faus-Kessler, Friederike Matheus, Antonio Simeone, Sabine M Hölter, Ralf Kühn, Daniela M Vogt Weisenhorn, Wolfgang Wurst, Nilima Prakas. FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PloS one. vol 9. issue 7. 2015-12-03. PMID:24983448. |
in this context, fgfr2-mediated signaling is required for the proper generation of bergmann glia cells and the correct positioning of these cells within the purkinje cell layer, and for cell survival in the developing cerebellar primordium. |
2015-12-03 |
2023-08-13 |
mouse |
| Elena Parmigiani, Ketty Leto, Chiara Rolando, María Figueres-Oñate, Laura López-Mascaraque, Annalisa Buffo, Ferdinando Ross. Heterogeneity and Bipotency of Astroglial-Like Cerebellar Progenitors along the Interneuron and Glial Lineages. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 19. 2015-07-27. PMID:25972168. |
indeed, the postnatal cerebellum hosts another germinal site along the purkinje cell layer (pcl), in which bergmann glia are generated up to first the postnatal weeks, which was proposed to be neurogenic. |
2015-07-27 |
2023-08-13 |
mouse |
| Yang Yang, Yongping Tang, Yan Xing, Meina Zhao, Xiaohang Bao, Dayu Sun, Xiaotong Tang, Yuzhang Wu, Haiwei Xu, Xiaotang Fa. Activation of liver X receptor is protective against ethanol-induced developmental impairment of Bergmann glia and Purkinje neurons in the mouse cerebellum. Molecular neurobiology. vol 49. issue 1. 2014-10-27. PMID:23900741. |
cerebellar purkinje cell and granule cell development are coordinated by bergmann glia, and are particularly sensitive to ethanol (etoh) exposure. |
2014-10-27 |
2023-08-12 |
mouse |
| Yang Yang, Yongping Tang, Yan Xing, Meina Zhao, Xiaohang Bao, Dayu Sun, Xiaotong Tang, Yuzhang Wu, Haiwei Xu, Xiaotang Fa. Activation of liver X receptor is protective against ethanol-induced developmental impairment of Bergmann glia and Purkinje neurons in the mouse cerebellum. Molecular neurobiology. vol 49. issue 1. 2014-10-27. PMID:23900741. |
therefore, using immunohistochemistry, quantitative real-time pcr and western blot, we tested the possible protection of lxr agonist t0901317 (t0) on bergmann glia and purkinje cell dendritogenesis in mice exposed to ethanol. |
2014-10-27 |
2023-08-12 |
mouse |
| Hiroki Shiwaku, Saburo Yagishita, Yoshinobu Eishi, Hitoshi Okazaw. Bergmann glia are reduced in spinocerebellar ataxia type 1. Neuroreport. vol 24. issue 11. 2014-03-05. PMID:23778076. |
we reported previously that mutant ataxin-1, a causative gene product of spinocerebellar ataxia type 1 (sca1), prevents bergmann glia proliferation in mutant ataxin-1 knockin mice and that suppressed bergmann glia function leads to purkinje cell degeneration. |
2014-03-05 |
2023-08-12 |
mouse |
| Hiroki Shiwaku, Saburo Yagishita, Yoshinobu Eishi, Hitoshi Okazaw. Bergmann glia are reduced in spinocerebellar ataxia type 1. Neuroreport. vol 24. issue 11. 2014-03-05. PMID:23778076. |
however, because reactive astrocytes are produced in response to brain injuries and diseases, bergmann glia are also suspected to proliferate and increase in response to purkinje cell degeneration, including during sca1 pathogenesis. |
2014-03-05 |
2023-08-12 |
mouse |
| Samia Habbas, Fabrice Ango, Hervé Daniel, Micaela Galant. Purinergic signaling in the cerebellum: Bergmann glial cells express functional ionotropic P2X7 receptors. Glia. vol 59. issue 12. 2013-07-08. PMID:21830236. |
potentially acting through both purinergic metabotropic p2y receptors (p2yrs) and ionotropic p2x receptors (p2xrs), up until now atp has only been shown to activate p2yrs in bergmann cells, the radial glia of the cerebellar cortex that envelopes purkinje cell afferent synapses. |
2013-07-08 |
2023-08-12 |
mouse |
| Xiaohong Wang, Tetsuya Imura, Michael V Sofroniew, Shinji Fushik. Loss of adenomatous polyposis coli in Bergmann glia disrupts their unique architecture and leads to cell nonautonomous neurodegeneration of cerebellar Purkinje neurons. Glia. vol 59. issue 6. 2012-03-26. PMID:21381115. |
using conditional knockout (cko) mice in which the apc gene is inactivated in glial fibrillary acidic protein (gfap)-expressing cells, we show a selective and critical role for apc in maintaining the morphology and function of cerebellar bergmann glia, which are specialized astroglia that extend polarized radial processes from the purkinje cell layer to the pial surface. |
2012-03-26 |
2023-08-12 |
mouse |
| Zhengshan Zhao, Jing Wang, Chunying Zhao, Weina Bi, Zhenyu Yue, Zhongmin Alex M. Genetic ablation of PLA2G6 in mice leads to cerebellar atrophy characterized by Purkinje cell loss and glial cell activation. PloS one. vol 6. issue 10. 2012-03-26. PMID:22046428. |
genetic ablation of pla2g6 in mice leads to cerebellar atrophy characterized by purkinje cell loss and glial cell activation. |
2012-03-26 |
2023-08-12 |
mouse |
| Parthiv Haldipur, Upasna Bharti, Corinne Alberti, Chitra Sarkar, Geetika Gulati, Soumya Iyengar, Pierre Gressens, Shyamala Man. Preterm delivery disrupts the developmental program of the cerebellum. PloS one. vol 6. issue 8. 2012-02-15. PMID:21858122. |
the two groups were assessed on quantitative measures that included molecular markers of granule neuron, purkinje neuron and bergmann glia differentiation, as well as the expression of the sonic hedgehog signaling pathway, that is important for cerebellar growth. |
2012-02-15 |
2023-08-12 |
human |