| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F J Sei. Interactions between cerebellar Purkinje cells and their associated astrocytes. Histology and histopathology. vol 16. issue 3. 2002-02-08. PMID:11510987. |
when granule cell neurons and functional glia were eliminated from newborn mouse cerebellar cultures by initial exposure to a dna synthesis inhibitor, purkinje cells lacked glial sheaths and there was a tremendous sprouting of purkinje cell recurrent axon collaterals, terminals of which hyperinnervated purkinje cell somata, including persistent somatic spines, and formed heterotypical synapses with purkinje cell dendritic spines, sites usually occupied by parallel fiber (granule cell axon) terminals. |
2002-02-08 |
2023-08-12 |
mouse |
| F J Sei. Interactions between cerebellar Purkinje cells and their associated astrocytes. Histology and histopathology. vol 16. issue 3. 2002-02-08. PMID:11510987. |
when cerebellar cultures without granule cells and glia were transplanted with granule cells and/or glia from another source, a series of changes occurred that included stripping of excess purkinje cell axosomatic synapses by astrocytic processes, reduction of heterotypical axospinous synapses in the presence of astrocytes, disappearance of purkinje cell somatic spines with astrocytic ensheathment, and proliferation of purkinje cell dendritic spines after the introduction of astrocytes. |
2002-02-08 |
2023-08-12 |
mouse |
| B J Gibb, J Garthwait. Subunits of the nitric oxide receptor, soluble guanylyl cyclase, expressed in rat brain. The European journal of neuroscience. vol 13. issue 3. 2001-04-26. PMID:11168561. |
in the cerebellum, alpha 1 and beta 1 message was strong in the purkinje cell layer but was not confined to purkinje cells: smaller cells, presumed to be the bergmann glia, were also labelled. |
2001-04-26 |
2023-08-12 |
rat |
| S Morara, A Rosina, L Provini, G Forloni, A Caretti, S J Wimalawans. Calcitonin gene-related peptide receptor expression in the neurons and glia of developing rat cerebellum: an autoradiographic and immunohistochemical analysis. Neuroscience. vol 100. issue 2. 2000-11-28. PMID:11008176. |
from the end of the second postnatal week to adulthood, when calcitonin gene-related peptide is no longer present in climbing fibers, the number of calcitonin gene-related peptide binding sites increased in the molecular layer, where not only bergmann glia but also purkinje cell distal dendritic branchlets were immunolabeled in a presumptive cell surface location. |
2000-11-28 |
2023-08-12 |
human |
| T Sharshar, I Auriant, A Dorandeu, M Saghatchian, L Bélec, B Benyahia, M Mabro, J C Raphaël, P Gajdos, J Y Delattre, F Gra. Association of herpes simplex virus encephalitis and paraneoplastic encephalitis - a clinico-pathological study. Annales de pathologie. vol 20. issue 3. 2000-09-12. PMID:10891724. |
postmortem examination showed necrotic and hemorrhagic lesions in the temporal lobes characteristic of herpes simplex virus encephalitis, which was confirmed by immunocytochemistry, and purkinje cell loss with proliferation of bergman glia and myelin loss in the external aspect of the dentate nuclei characteristic of paraneoplastic encephalitis. |
2000-09-12 |
2023-08-12 |
Not clear |
| N Dahmane, A Ruiz i Altab. Sonic hedgehog regulates the growth and patterning of the cerebellum. Development (Cambridge, England). vol 126. issue 14. 1999-08-19. PMID:10375501. |
blocking shh function in vivo results in deficient granule neuron and bergmann glia differentiation as well as in abnormal purkinje neuron development. |
1999-08-19 |
2023-08-12 |
Not clear |
| F J Sei. The extracellular matrix molecule, laminin, induces purkinje cell dendritic spine proliferation in granule cell depleted cerebellar cultures. Brain research. vol 795. issue 1-2. 1998-08-19. PMID:9622607. |
transplantation of such granuloprival cultures with glia or exposure to astrocyte conditioned medium in the absence of parallel fibers (granule cell axons) resulted in proliferation of purkinje cell dendritic spines. |
1998-08-19 |
2023-08-12 |
Not clear |
| F J Sei. Cerebellar culture models of dendritic spine proliferation after transplantation of glia. Journal of neural transplantation & plasticity. vol 6. issue 1. 1997-03-19. PMID:8959546. |
studies of purkinje cell dendritic spine proliferation after transplantation of cytosine arabinoside (ara c) treated organotypic cerebellar cultures with glia and granule cells, either separately and in combination, were reviewed. |
1997-03-19 |
2023-08-12 |
Not clear |
| F J Sei. Cerebellar culture models of dendritic spine proliferation after transplantation of glia. Journal of neural transplantation & plasticity. vol 6. issue 1. 1997-03-19. PMID:8959546. |
transplantation of ara c-treated cultures with glia alone resulted in a proliferation of clusters of purkinje cell dendritic spines, but in the absence of granule cells the spines remained unattached, and the clusters persisted throughout the period of observation. |
1997-03-19 |
2023-08-12 |
Not clear |
| F J Sei. Cerebellar culture models of dendritic spine proliferation after transplantation of glia. Journal of neural transplantation & plasticity. vol 6. issue 1. 1997-03-19. PMID:8959546. |
when ara c-treated cerebellar cultures were transplanted with granule cells in the absence of functional glia, parallel fiber- purkinje cell dendritic spine synapses formed, but no clusters of purkinje cell dendritic spines were observed. |
1997-03-19 |
2023-08-12 |
Not clear |
| S A Bayer, K V Wills, J Wei, Y Feng, S R Dlouhy, M E Hodes, T Verina, B Ghett. Phenotypic effects of the weaver gene are evident in the embryonic cerebellum but not in the ventral midbrain. Brain research. Developmental brain research. vol 96. issue 1-2. 1997-03-11. PMID:8922675. |
quantitative measures of the following features showed stepwise differences between genotypes so that the wv/wv are most affected and wv/+ are somewhat affected compared with +/+: surface length of the midline vermis, area of the entire midline vermis and the external germinal layer (egl), total number of cells in the egl, [3h]thymidine-labeled and -unlabeled egl cells, cells in the purkinje cell layer, cells in the region of the deep nuclei, [3h]thymidine-labeled cells in the purkinje cell layer (presumptive proliferating bergmann glia), and [3h]thymidine-labeled cells in the region of the deep nuclei. |
1997-03-11 |
2023-08-12 |
mouse |
| V T Garyfallou, S G Kohama, H F Urbansk. Distribution of NMDA and AMPA receptors in the cerebellar cortex of rhesus macaques. Brain research. vol 716. issue 1-2. 1996-10-25. PMID:8738216. |
although glur2/3 immunolabeling also occurred in these bergmann glia processes as well as in the bergmann fibers, it was more pronounced in the purkinje cell perikarya and dendrites; additionally, significant glur2/3 labeling was evident in the stellate and basket cells of the molecular layer and medium-size soma of the granular layer (most likely golgi cells). |
1996-10-25 |
2023-08-12 |
monkey |
| Y Bailly, S W Schoen, N Delhaye-Bouchaud, G W Kreutzberg, J Marian. 5'-nucleotidase activity as a synaptic marker of parasagittal compartmentation in the mouse cerebellum. Journal of neurocytology. vol 24. issue 11. 1996-03-14. PMID:8576716. |
thus, 5'-nucleotidase appears as a marker of glia and of purkinje cell synapses across cerebellar compartments. |
1996-03-14 |
2023-08-12 |
mouse |
| F J Seil, R Drake-Bauman. Circuit reorganization in granuloprival cerebellar cultures in the absence of neuronal activity. The Journal of comparative neurology. vol 356. issue 4. 1995-10-31. PMID:7560266. |
neonatal mouse cerebellar cultures exposed to cytosine arabinoside for the first 5 days in vitro to destroy granule cells and compromise glia undergo a circuit reorganization featured by profuse sprouting of purkinje cell recurrent axon collaterals, which hyperinnervate the somata of other purkinje cells and project to purkinje cell dendritic spines. |
1995-10-31 |
2023-08-12 |
mouse |
| F J Sei. Plastic changes in Ara C-treated and "transplanted" coeruleocerebellar cultures. Brain research bulletin. vol 35. issue 5-6. 1995-03-21. PMID:7859101. |
when coeruleocerebellar cultures are exposed to cytosine arabinoside to destroy cerebellar granule cells and functionally compromise glia, there is a resultant increase of purkinje cell survival and a sprouting of purkinje cell recurrent axon collaterals, plus an increase of catecholaminergic axons accompanied by a doubling of tissue dopamine content. |
1995-03-21 |
2023-08-12 |
Not clear |
| F J Sei. Plastic changes in Ara C-treated and "transplanted" coeruleocerebellar cultures. Brain research bulletin. vol 35. issue 5-6. 1995-03-21. PMID:7859101. |
if such reorganized cultures are transplanted with granule cells and glia, a second round of plastic changes ensues in which the purkinje cell population and the recurrent axon collaterals are reduced to control levels, but catecholaminergic axons and dopamine content remain increased. |
1995-03-21 |
2023-08-12 |
Not clear |
| B J Anderson, X Li, A A Alcantara, K R Isaacs, J E Black, W T Greenoug. Glial hypertrophy is associated with synaptogenesis following motor-skill learning, but not with angiogenesis following exercise. Glia. vol 11. issue 1. 1994-09-29. PMID:7520887. |
the skill learning group had a greater volume of molecular layer per purkinje cell, and also a greater volume of glia per purkinje cell, than rats in either an inactive group or rats in two exercise groups. |
1994-09-29 |
2023-08-12 |
rat |
| J Sievers, F W Pehlemann, S Gude, M Berr. A time course study of the alterations in the development of the hamster cerebellar cortex after destruction of the overlying meningeal cells with 6-hydroxydopamine on the day of birth. Journal of neurocytology. vol 23. issue 2. 1994-06-28. PMID:8195811. |
this treatment destroys the overlying meningeal cells, the sequelae of which include (i) a thinning of the external granular layer over the folial apices and a thickening in the region of the prospective fissures, reflecting a retardation of the growth of the cerebellar cortex, accompanied by displacement of the normally superficialmost gfap-positive external granular layer cells into deeper parts of the external granular layer; (ii) a retardation of multiplication of golgi epithelial cells which colonize the rostral third of the purkinje cell layer so that their numbers decrease in the rostralmost folia; (iii) disturbed morphological and biochemical differentiation of the golgi epithelial cells and their processes, the growing radial bergmann glial fibres which detach from the pial surface and branch within the external granular layer, causing a failure in endfeet formation at the superficial glia limitans, loss of characteristic radial morphology, with the adoption of a multipolar form, and normal or increased gfap expression and decreased s-100 expression; (iv) fragmentation of the external granular layer beyond p5 to p7 with loss of the regular lamination and foliation of the cerebellar cortex, characterized by a completely random distribution of fragments of purkinje cell layer, molecular zone and internal granular layer. |
1994-06-28 |
2023-08-12 |
Not clear |
| S Yuasa, J Kitoh, S Oda, K Kawamur. Obstructed migration of Purkinje cells in the developing cerebellum of the reeler mutant mouse. Anatomy and embryology. vol 188. issue 4. 1994-02-07. PMID:7506500. |
we examined the process of purkinje cell migration in the cerebellar primordium of the reeler mutant immunohistochemically and electron-microscopically, employing a specific marker for purkinje cells and markers for radial glia. |
1994-02-07 |
2023-08-12 |
mouse |
| S Yuasa, J Kitoh, S Oda, K Kawamur. Obstructed migration of Purkinje cells in the developing cerebellum of the reeler mutant mouse. Anatomy and embryology. vol 188. issue 4. 1994-02-07. PMID:7506500. |
these findings suggest that the obstructed migration and disordered cortical alignment of purkinje cells in the reeler cerebellum is due to dysgenesis and abnormal development of radial glia, resulting in disturbance of contact guidance in the process of purkinje cell migration. |
1994-02-07 |
2023-08-12 |
mouse |