| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Isabel Rocha, Marta González-García, Laura Carrillo-Franco, Marc Stefan Dawid-Milner, Manuel Victor López-Gonzále. Influence of Brainstem's Area A5 on Sympathetic Outflow and Cardiorespiratory Dynamics. Biology. vol 13. issue 3. 2024-03-27. PMID:38534431. |
area a5 is a noradrenergic cell group in the brain stem characterised by its important role in triggering sympathetic activity, exerting a profound influence on the sympathetic outflow, which is instrumental in the modulation of cardiovascular functions, stress responses and various other physiological processes that are crucial for adaptation and survival mechanisms. |
2024-03-27 |
2024-03-29 |
Not clear |
| Charles Rodenkirch, Qi Wan. Optimization of Temporal Coding of Tactile Information in Rat Thalamus by Locus Coeruleus Activation. Biology. vol 13. issue 2. 2024-02-23. PMID:38392298. |
the brainstem noradrenergic nucleus, the locus coeruleus (lc), exerts heavy influences on sensory processing, perception, and cognition through its diffuse projections throughout the brain. |
2024-02-23 |
2024-02-25 |
rat |
| Beniamina Mercante, Paolo Enrico, Franca Deri. Cognitive Functions following Trigeminal Neuromodulation. Biomedicines. vol 11. issue 9. 2023-09-28. PMID:37760833. |
on these bases, a bottom-up mechanism has been proposed, positing that tns-induced modulation of the brainstem noradrenergic system may affect the function of the brain networks involved in cognition. |
2023-09-28 |
2023-10-07 |
Not clear |
| Rachel A Matt, Frederick G Westhorpe, Rosemary F Romuar, Payal Rana, Joel R Gever, Anthony P For. Fingerprinting heterocellular β-adrenoceptor functional expression in the brain using agonist activity profiles. Frontiers in molecular biosciences. vol 10. 2023-09-04. PMID:37664183. |
noradrenergic projections from the brainstem locus coeruleus drive arousal, attentiveness, mood, and memory, but specific adrenoceptor (ar) function across the varied brain cell types has not been extensively characterized, especially with agonists. |
2023-09-04 |
2023-09-07 |
Not clear |
| Yu Arihara, Yudai Fukuyama, Satoshi Kid. Consolidation, reconsolidation, and extinction of contextual fear memory depend on de novo protein synthesis in the locus coeruleus. Brain research bulletin. 2023-08-21. PMID:37604301. |
the locus coeruleus (lc) is a small nucleus in the brain stem that is composed predominantly of noradrenergic neurons that project to many brain regions. |
2023-08-21 |
2023-09-07 |
Not clear |
| Simon Levinson, Michelle Miller, Ahmed Iftekhar, Monica Justo, Daniel Arriola, Wenxin Wei, Saman Hazany, Josue M Avecillas-Chasin, Taylor P Kuhn, Andreas Horn, Ausaf A Bar. A structural connectivity atlas of limbic brainstem nuclei. Frontiers in neuroimaging. vol 1. 2023-08-09. PMID:37555163. |
several brainstem nuclei have been identified as the primary central nervous system (cns) source of important monoaminergic ascending fibers including the noradrenergic locus coeruleus, serotonergic dorsal raphe nucleus, and dopaminergic ventral tegmental area. |
2023-08-09 |
2023-08-16 |
Not clear |
| Prokopis C Prokopiou, Nina Engels-Domínguez, Aaron P Schultz, Jorge Sepulcre, Elouise A Koops, Kathryn V Papp, Gad A Marshall, Marc D Normandin, Georges El Fakhri, Dorene Rentz, Reisa A Sperling, Keith A Johnson, Heidi I L Jacob. Association of Novelty-Related Locus Coeruleus Function With Entorhinal Tau Deposition and Memory Decline in Preclinical Alzheimer Disease. Neurology. 2023-07-25. PMID:37491329. |
whether similar mechanisms explain tau progression from the locus coeruleus (lc), a tiny noradrenergic brainstem nucleus involved in novelty, learning, and memory and among the earliest regions to accumulate tau, has not yet been established. |
2023-07-25 |
2023-08-14 |
human |
| Adele Romano, Marzia Friuli, Barbara Eramo, Cristina Anna Gallelli, Justyna Barbara Koczwara, Elnaz Karimian Azari, Adrien Paquot, Myrtha Arnold, Wolfgang Langhans, Giulio G Muccioli, Thomas Alexander Lutz, Silvana Gaetan. "To brain or not to brain": evaluating the possible direct effects of the satiety factor oleoylethanolamide in the central nervous system. Frontiers in endocrinology. vol 14. 2023-05-26. PMID:37234803. |
numerous observations suggested that the oea effects might be peripherally mediated, although they involve central pathways including noradrenergic, histaminergic and oxytocinergic systems of the brainstem and the hypothalamus. |
2023-05-26 |
2023-08-14 |
Not clear |
| Hai-Tao Ma, Hao-Chen Zhang, Zhong-Fu Zuo, Ying-Xue Li. Heterogeneous organization of Locus coeruleus: An intrinsic mechanism for functional complexity. Physiology & behavior. 2023-05-12. PMID:37172640. |
locus coeruleus (lc) is a small nucleus located deep in the brainstem that contains the majority of central noradrenergic neurons, which provide the primary source of noradrenaline (na) throughout the entire central nervous system (cns).the release of neurotransmitter na is considered to modulate arousal, sensory processing, attention, aversive and adaptive stress responses as well as high-order cognitive function and memory, with the highly ramified axonal arborizations of lc-na neurons sending wide projections to the targeted brain areas. |
2023-05-12 |
2023-08-14 |
Not clear |
| Kanza M Khan, Nagalakshmi Balasubramanian, Gabriel Gaudencio, Ruixiang Wang, Govindhasamy Pushpavathi Selvakumar, Louis Kolling, Samantha Pierson, Satya M Tadinada, Ted Abel, Marco Hefti, Catherine A Marcinkiewc. Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer's disease. Acta neuropathologica communications. vol 11. issue 1. 2023-04-03. PMID:37009893. |
in total, these results suggest that tau pathology in brainstem monoaminergic nuclei and the resulting loss of serotonergic and/or noradrenergic drive may underpin depressive- and anxiety-like behaviors in the early stages of ad. |
2023-04-03 |
2023-08-14 |
mouse |
| Jonnathan Singh Alvarado, Jordan Hatfield, Richard Moone. Divergent projections from locus coeruleus to the corticobasal ganglia system and ventral tegmental area of the adult male zebra finch. The Journal of comparative neurology. 2023-03-28. PMID:36976533. |
the locus coeruleus (lc) is a small noradrenergic brainstem nucleus that plays a central role in regulating arousal, attention, and performance. |
2023-03-28 |
2023-08-14 |
Not clear |
| Lindsay J Agostinelli, Scott C Seaman, Clifford B Saper, Dustin Fykstra, Marco M Hefti, Timothy R Koscik, Brian J Dlouhy, Alexander G Bassu. Human Brainstem and Cerebellum Atlas- Chemoarchitecture and Cytoarchitecture Paired to MRI. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-11-28. PMID:36442999. |
here, we report a high resolution (200 μm) 7t mri of a cadaveric male human brainstem and cerebellum paired with detailed, coregistered histology (at 2 μm single cell resolution) of the immunohistochemically stained cholinergic, serotonergic, and catecholaminergic (dopaminergic noradrenergic and adrenergic) neurons, in relationship to each other and to the cerebellum. |
2022-11-28 |
2023-08-14 |
human |
| Lazaros C Triarhou, Mario Mant. The Discovery of the Monoaminergic Innervation of the Cerebellum: Convergence of Divergent and Point-to-Point Systems. Cerebellum (London, England). 2022-09-23. PMID:36149526. |
the discovery of noradrenergic and serotoninergic innervation of the cerebellum has been a crucial step in understanding the neurochemical relationships between brainstem nuclei and the cerebellum, and the attempts to treat cerebellar ataxias pharmacologically. |
2022-09-23 |
2023-08-14 |
Not clear |
| Osvaldo Delbono, Zhong-Min Wang, María Laura Mess. Brainstem Noradrenergic Neurons: Identifying a Hub at the Intersection of Cognition, Motility, and Skeletal Muscle Regulation. Acta physiologica (Oxford, England). 2022-09-08. PMID:36073023. |
brainstem noradrenergic neurons: identifying a hub at the intersection of cognition, motility, and skeletal muscle regulation. |
2022-09-08 |
2023-08-14 |
Not clear |
| Osvaldo Delbono, Zhong-Min Wang, María Laura Mess. Brainstem Noradrenergic Neurons: Identifying a Hub at the Intersection of Cognition, Motility, and Skeletal Muscle Regulation. Acta physiologica (Oxford, England). 2022-09-08. PMID:36073023. |
brainstem noradrenergic neuron clusters form a node integrating efferents projecting to distinct areas such as those regulating cognition and skeletal muscle structure and function, and receives dissimilar afferents through established circuits to coordinate organismal responses to internal and environmental challenges. |
2022-09-08 |
2023-08-14 |
Not clear |
| Osvaldo Delbono, Zhong-Min Wang, María Laura Mess. Brainstem Noradrenergic Neurons: Identifying a Hub at the Intersection of Cognition, Motility, and Skeletal Muscle Regulation. Acta physiologica (Oxford, England). 2022-09-08. PMID:36073023. |
genetic lineage tracing shows the remarkable heterogeneity of brainstem noradrenergic neurons, which may explain their varied functions. |
2022-09-08 |
2023-08-14 |
Not clear |
| Osvaldo Delbono, Zhong-Min Wang, María Laura Mess. Brainstem Noradrenergic Neurons: Identifying a Hub at the Intersection of Cognition, Motility, and Skeletal Muscle Regulation. Acta physiologica (Oxford, England). 2022-09-08. PMID:36073023. |
synapse between descending brainstem noradrenergic neurons and preganglionic spinal neurons, and these in turn with postganglionic noradrenergic neurons located at the paravertebral sympathetic ganglia, support an anatomical hierarchy that regulates skeletal muscle innervation, neuromuscular transmission, and muscle trophism. |
2022-09-08 |
2023-08-14 |
Not clear |
| Xiaoqing Alice Zhou, Yuanyuan Jiang, Vitaly Napadow, Xin Y. Challenges and Perspectives of Mapping Locus Coeruleus Activity in the Rodent with High-Resolution fMRI. Brain sciences. vol 12. issue 8. 2022-08-26. PMID:36009148. |
specifically, noradrenergic (na) lc neurons not only connect globally to higher-order subcortical nuclei and cortex to mediate arousal and attention but also directly project to other brainstem nuclei and to the spinal cord to control autonomic function. |
2022-08-26 |
2023-08-14 |
mouse |
| R Pinelli, D Bucci, E Scaffidi, C Berti, V Bumah, G Lazzeri, R Ruffoli, S Puglisi-Allegra, C L Busceti, F Forna. Noradrenergic substrates sensing light within brainstem reticular formation as targets for light-induced behavioral and cardiovascular plasticity. Archives italiennes de biologie. vol 160. issue 1-2. 2022-08-01. PMID:35913389. |
noradrenergic substrates sensing light within brainstem reticular formation as targets for light-induced behavioral and cardiovascular plasticity. |
2022-08-01 |
2023-08-14 |
human |
| R Pinelli, D Bucci, E Scaffidi, C Berti, V Bumah, G Lazzeri, R Ruffoli, S Puglisi-Allegra, C L Busceti, F Forna. Noradrenergic substrates sensing light within brainstem reticular formation as targets for light-induced behavioral and cardiovascular plasticity. Archives italiennes de biologie. vol 160. issue 1-2. 2022-08-01. PMID:35913389. |
according to this evidence, a retino-reticular monosynaptic system occurs, which powerfully modulate the noradrenergic hub of reticular nuclei in the lateral column of the brainstem reticular formation. |
2022-08-01 |
2023-08-14 |
human |