| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patricia Pais-Roldán, Kengo Takahashi, Filip Sobczak, Yi Chen, Xiaoning Zhao, Hang Zeng, Yuanyuan Jiang, Xin Y. Indexing brain state-dependent pupil dynamics with simultaneous fMRI and optical fiber calcium recording. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 12. 2020-07-07. PMID:32139609. |
besides, a specific correlation pattern was detected in the brainstem, at a location consistent with noradrenergic cell group 5 (a5), which appeared to be dependent on the coupling between different frequencies of cortical activity, possibly further indicating particular brain-state dynamics. |
2020-07-07 |
2023-08-13 |
human |
| Yu Mu, Davis V Bennett, Mikail Rubinov, Sujatha Narayan, Chao-Tsung Yang, Masashi Tanimoto, Brett D Mensh, Loren L Looger, Misha B Ahren. Glia Accumulate Evidence that Actions Are Futile and Suppress Unsuccessful Behavior. Cell. vol 178. issue 1. 2020-04-06. PMID:31230713. |
using cell ablation and optogenetic or chemogenetic activation, we found that noradrenergic neurons progressively activated brainstem radial astrocytes, which then suppressed swimming. |
2020-04-06 |
2023-08-13 |
zebrafish |
| Samira Aminihajibashi, Thomas Hagen, Maja Dyhre Foldal, Bruno Laeng, Thomas Espeset. Individual differences in resting-state pupil size: Evidence for association between working memory capacity and pupil size variability. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 140. 2020-04-02. PMID:30894328. |
dynamic non-luminance-mediated changes in pupil diameter have frequently been shown to be a reliable index for the level of arousal, mental effort, and activity in the locus coeruleus, the brainstem's noradrenergic arousal center. |
2020-04-02 |
2023-08-13 |
human |
| Péter Zahola, János Hanics, Anna Pintér, Zoltán Máté, Anna Gáspárdy, Zsófia Hevesi, Diego Echevarria, Csaba Adori, Swapnali Barde, Beáta Törőcsik, Ferenc Erdélyi, Gábor Szabó, Ludwig Wagner, Gabor G Kovacs, Tomas Hökfelt, Tibor Harkany, Alán Alpá. Secretagogin expression in the vertebrate brainstem with focus on the noradrenergic system and implications for Alzheimer's disease. Brain structure & function. vol 224. issue 6. 2020-01-02. PMID:31144035. |
secretagogin expression in the vertebrate brainstem with focus on the noradrenergic system and implications for alzheimer's disease. |
2020-01-02 |
2023-08-13 |
mouse |
| Péter Zahola, János Hanics, Anna Pintér, Zoltán Máté, Anna Gáspárdy, Zsófia Hevesi, Diego Echevarria, Csaba Adori, Swapnali Barde, Beáta Törőcsik, Ferenc Erdélyi, Gábor Szabó, Ludwig Wagner, Gabor G Kovacs, Tomas Hökfelt, Tibor Harkany, Alán Alpá. Secretagogin expression in the vertebrate brainstem with focus on the noradrenergic system and implications for Alzheimer's disease. Brain structure & function. vol 224. issue 6. 2020-01-02. PMID:31144035. |
notably, secretagogin expression overlapped with the brainstem column of noradrenergic cell bodies, including the locus coeruleus (a6) and the a1, a5 and a7 fields. |
2020-01-02 |
2023-08-13 |
mouse |
| Duygu Gok-Yurtseven, Ilker M Kafa, Zehra Minbay, Ozhan Eyigo. Glutamatergic activation of A1 and A2 noradrenergic neurons in the rat brain stem. Croatian medical journal. vol 60. issue 4. 2019-12-19. PMID:31483121. |
glutamatergic activation of a1 and a2 noradrenergic neurons in the rat brain stem. |
2019-12-19 |
2023-08-13 |
rat |
| Robert Kaczmarczyk, Dario Tejera, Bruce J Simon, Michael T Henek. Microglia modulation through external vagus nerve stimulation in a murine model of Alzheimer's disease. Journal of neurochemistry. 2019-11-20. PMID:29266221. |
the vagus nerve projects to the brainstem's locus coeruleus from which noradrenergic fibers reach to the nucleus basalis of meynert (nbm) and widely throughout the brain. |
2019-11-20 |
2023-08-13 |
mouse |
| N M Holmes, J W Crane, M Tang, J Fam, R F Westbrook, A J Delane. α Scientific reports. vol 7. issue 1. 2019-07-15. PMID:28916748. |
this region receives a dense innervation from brainstem noradrenergic cell groups and has a high level of α |
2019-07-15 |
2023-08-13 |
Not clear |
| Mauricio Vallejo, Joseph M Santin, Lynn K Hartzle. Noradrenergic modulation determines respiratory network activity during temperature changes in the in vitro brainstem of bullfrogs. Respiratory physiology & neurobiology. vol 258. 2019-03-29. PMID:30292742. |
noradrenergic modulation determines respiratory network activity during temperature changes in the in vitro brainstem of bullfrogs. |
2019-03-29 |
2023-08-13 |
Not clear |
| Cynthia A Kelm-Nelson, Michael A Trevino, Michelle R Ciucc. Quantitative Analysis of Catecholamines in the Pink1 -/- Rat Model of Early-onset Parkinson's Disease. Neuroscience. vol 379. 2019-03-18. PMID:29496635. |
moreover, an observed decrease in norepinephrine concentrations in the lc is consistent with the hypothesis that early-stage pd includes noradrenergic loss in the brainstem, and is congruent with a significant increase in catechol-o-methyltransferase expression in the lc of pink1 -/- animals. |
2019-03-18 |
2023-08-13 |
rat |
| Cynthia A Kelm-Nelson, Michael A Trevino, Michelle R Ciucc. Quantitative Analysis of Catecholamines in the Pink1 -/- Rat Model of Early-onset Parkinson's Disease. Neuroscience. vol 379. 2019-03-18. PMID:29496635. |
these data support the evolving hypothesis that differences in neural substrates and early-onset noradrenergic mechanisms in the brainstem may contribute to pathogenesis in the pink1 -/- rat. |
2019-03-18 |
2023-08-13 |
rat |
| Pia-Maria Wippert, Christine Wiebkin. Stress and Alterations in the Pain Matrix: A Biopsychosocial Perspective on Back Pain and Its Prevention and Treatment. International journal of environmental research and public health. vol 15. issue 4. 2019-02-13. PMID:29670003. |
specifically, long-term demands on the stress response system may moderate central pain processing and influence descending serotonergic and noradrenergic signals from the brainstem, regulating nociceptive processing at the spinal level. |
2019-02-13 |
2023-08-13 |
Not clear |
| Yukako Hino, Ayumi Koyanagi, Motohiro Maebuchi, Takashi Ichinose, Shigeki Furuy. Comparison of the Effect of Soy and Casein-Derived Peptide Administration on Tyrosine and Catecholamine Metabolism in the Mouse Brain. Journal of nutritional science and vitaminology. vol 64. issue 5. 2019-01-16. PMID:30381622. |
in addition to tyrosine, soy peptide administration also led to an effective augmentation of 3-methoxy-4-hydroxyphenylethyleneglycol (mhpg), a principal metabolite of noradrenaline, and significant facilitation of noradrenergic turnover in the cerebral cortex, brainstem, and hippocampus compared to the vehicle control. |
2019-01-16 |
2023-08-13 |
mouse |
| Yukako Hino, Ayumi Koyanagi, Motohiro Maebuchi, Takashi Ichinose, Shigeki Furuy. Comparison of the Effect of Soy and Casein-Derived Peptide Administration on Tyrosine and Catecholamine Metabolism in the Mouse Brain. Journal of nutritional science and vitaminology. vol 64. issue 5. 2019-01-16. PMID:30381622. |
casein peptide administration also led to an increase in mhpg only in the cerebral cortex, and caused facilitation of noradrenergic turnover in the cerebral cortex and brainstem. |
2019-01-16 |
2023-08-13 |
mouse |
| Vincent D Campese, Jose M Soroeta, Elena M Vazey, Gary Aston-Jones, Joseph E LeDoux, Robert M Sear. Noradrenergic Regulation of Central Amygdala in Aversive Pavlovian-to-Instrumental Transfer. eNeuro. vol 4. issue 5. 2018-06-11. PMID:29071299. |
in the current studies, using pharmacology and designer receptors in rodents, we demonstrate that noradrenergic (ne) activity negatively regulates pit via brainstem locus coeruleus (lc) activity and lc projections to cea. |
2018-06-11 |
2023-08-13 |
Not clear |
| Chris Mezias, Eve LoCastro, Chuying Xia, Ashish Ra. Connectivity, not region-intrinsic properties, predicts regional vulnerability to progressive tau pathology in mouse models of disease. Acta neuropathologica communications. vol 5. issue 1. 2018-05-07. PMID:28807028. |
for instance, ad has a progression of tau pathology consistently beginning in the entorhinal cortex, the locus coeruleus, and other nearby noradrenergic brainstem nuclei, before spreading to the rest of the limbic system as well as the cingulate and retrosplenial cortices. |
2018-05-07 |
2023-08-13 |
mouse |
| Ronald G Garcia, Richard L Lin, Jeungchan Lee, Jieun Kim, Riccardo Barbieri, Roberta Sclocco, Ajay D Wasan, Robert R Edwards, Bruce R Rosen, Nouchine Hadjikhani, Vitaly Napado. Modulation of brainstem activity and connectivity by respiratory-gated auricular vagal afferent nerve stimulation in migraine patients. Pain. vol 158. issue 8. 2018-05-01. PMID:28541256. |
regulation of activity and connectivity of brainstem and cortical regions involved in serotonergic and noradrenergic regulation and pain modulation may constitute an underlying mechanism supporting beneficial clinical outcomes for eravans applied for episodic migraine. |
2018-05-01 |
2023-08-13 |
Not clear |
| James W Maniscalco, Linda Rinama. Interoceptive modulation of neuroendocrine, emotional, and hypophagic responses to stress. Physiology & behavior. vol 176. 2018-03-08. PMID:28095318. |
the caudal brainstem contains two distinct populations of stress-recruited neurons [i.e., noradrenergic neurons of the a2 cell group that co-express prolactin-releasing peptide (prrp+ a2 neurons), and glucagon-like peptide 1 (glp-1) neurons] that also are responsive to interoceptive feedback about feeding and metabolic status. |
2018-03-08 |
2023-08-13 |
Not clear |
| Max Schneider, Pamela Hathway, Laura Leuchs, Philipp G Sämann, Michael Czisch, Victor I Spoormake. Spontaneous pupil dilations during the resting state are associated with activation of the salience network. NeuroImage. vol 139. 2018-02-05. PMID:27291493. |
in a combined rs-fmri/eye tracking study, the pupil size of 32 healthy subjects after 2h of sleep restriction was recorded as an indirect index for activity of the locus coeruleus, the brainstem's noradrenergic arousal center. |
2018-02-05 |
2023-08-13 |
human |
| Stefanie Köhler, Karl-Jürgen Bär, Gerd Wagne. Differential involvement of brainstem noradrenergic and midbrain dopaminergic nuclei in cognitive control. Human brain mapping. vol 37. issue 6. 2018-01-16. PMID:26970351. |
differential involvement of brainstem noradrenergic and midbrain dopaminergic nuclei in cognitive control. |
2018-01-16 |
2023-08-13 |
human |