| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ahmet Yardimci, Nazife Ulker Ertugrul, Aslisah Ozgen, Gulendam Ozbeg, Mehmet Ridvan Ozdede, Eda Coban Ercan, Sinan Canpola. Effects of chronic irisin treatment on brain monoamine levels in the hypothalamic and subcortical nuclei of adult male and female rats: An HPLC-ECD study. Neuroscience letters. 2023-04-15. PMID:37061025. |
on the other hand, it significantly decreased serotonin (5-ht) (p<0.01) and its metabolite 5-hiaa levels in the medial amygdala (mea) (p<0.05), indicating that it may play a role in social behaviors. |
2023-04-15 |
2023-08-14 |
rat |
| Hirohito Esaki, Yuki Sasaki, Naoya Nishitani, Hikari Kamada, Satoko Mukai, Yoshitaka Ohshima, Sao Nakada, Xiyan Ni, Satoshi Deyama, Katsuyuki Kaned. Role of 5-HT European journal of pharmacology. 2023-03-12. PMID:36907260. |
in the present study, we investigated whether 5-ht neurotransmission in the medial prefrontal cortex (mpfc) and the basolateral nucleus of amygdala (bla) is involved in mdma-induced prosocial effects using the social approach test in male icr mice. |
2023-03-12 |
2023-08-14 |
mouse |
| Elisa Giunti, Roberto Collu, Simona Dedoni, M Paola Castelli, Maria Scherma, Paola Fadd. Food restriction and hyperactivity induce changes in corticolimbic brain dopamine and serotonin levels in female rats. Behavioural brain research. 2023-03-02. PMID:36863461. |
we exposed female rats to the aba paradigm and measured the levels of da, 5-ht, and the metabolites 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 5-hydroxyindoleacetic acid (5-hiaa), and dopaminergic type 2 (d2) receptors density in feeding- and reward-implicated brain regions (i.e., cerebral cortex, cx; prefrontal cortex, pfc; caudate putamen, cpu; nucleus accumbens, nacc; amygdala, amy; hypothalamus, hyp; hippocampus, hipp). |
2023-03-02 |
2023-08-14 |
rat |
| Ching-Wen Chen, Yuan-Hwa Chou, Ying-Jay Liou, Kai-Chun Yang, Li-Yu Hu, Wen-Chi Hsieh, Mu-N Li. Amygdala substructure volumes and serotonin transporter in first-episode, drug- naïve major depressive disorder: A pilot study. Journal of psychiatric research. vol 160. 2023-03-01. PMID:36857985. |
amygdala substructure volumes and serotonin transporter in first-episode, drug- naïve major depressive disorder: a pilot study. |
2023-03-01 |
2023-08-14 |
Not clear |
| Takahiro Ito, Mikio Yoshida, Tomomi Aida, Itaru Kushima, Yuka Hiramatsu, Maiko Ono, Akira Yoshimi, Kohichi Tanaka, Norio Ozaki, Yukihiro Nod. Astrotactin2 (ASTN2) regulates emotional and cognitive functions by affecting neuronal morphogenesis and monoaminergic systems. Journal of neurochemistry. 2023-02-22. PMID:36807153. |
dopamine contents were decreased in the striatum, and serotonin or dopamine turnover were increased in the striatum, nucleus accumbens, and amygdala of astn2 ko mice. |
2023-02-22 |
2023-08-14 |
mouse |
| Laura C Fox, Jamie L Scholl, Michael J Watt, Gina L Forste. GABA Neuroscience. 2023-02-03. PMID:36736883. |
the hippocampus and amygdala are implicated in stress responses and anxiety, and within these regions, gamma-aminobutyric acid (gaba) and serotonin modulate output and behavioral expression. |
2023-02-03 |
2023-08-14 |
Not clear |
| R Janet, N Costes, I Mérida, E Derrington, J C Drehe. Relationships between serotonin availability and frontolimbic response to fearful and threatening faces. Scientific reports. vol 13. issue 1. 2023-01-27. PMID:36707612. |
although emotion processing is known to engage a corticolimbic circuit, including the amygdala and prefrontal cortex, exactly how this brain system is modulated by serotonin remains unclear. |
2023-01-27 |
2023-08-14 |
human |
| R Janet, N Costes, I Mérida, E Derrington, J C Drehe. Relationships between serotonin availability and frontolimbic response to fearful and threatening faces. Scientific reports. vol 13. issue 1. 2023-01-27. PMID:36707612. |
these results demonstrate the association between the serotonin transporter level and emotion processing through changes in functional interactions between the amygdala and the prefrontal areas in healthy humans. |
2023-01-27 |
2023-08-14 |
human |
| Stefania Dimonte, Vladyslav Sikora, Maria Bove, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592494. |
social isolation also caused a reduction of noradrenaline, serotonin and gaba levels, together with an increase of serotonin turnover and glutamate levels in the amygdala of isolated animals. |
2023-01-02 |
2023-08-14 |
human |
| Xiao-Dan Yu, Yi Zhu, Qi-Xin Sun, Fei Deng, Jinxia Wan, Di Zheng, Wankun Gong, Shi-Ze Xie, Chen-Jie Shen, Jia-Yu Fu, Huiqian Huang, Hsin-Yi Lai, Jin Jin, Yulong Li, Xiao-Ming L. Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety. Nature neuroscience. vol 25. issue 12. 2022-11-29. PMID:36446933. |
we demonstrate that in mice, social and anxiogenic stimuli, respectively, increase and decrease serotonin (5-ht) levels in basal amygdala (ba). |
2022-11-29 |
2023-08-14 |
mouse |
| Niklas Reich, Christian Hölsche. Beyond Appetite: Acylated Ghrelin As A Learning, Memory and Fear Behavior-modulating Hormone. Neuroscience and biobehavioral reviews. 2022-11-11. PMID:36368526. |
as such, in this review, we i) evaluate what specific stages and forms of memory, as well as which respective brain areas are affected by acylated ghrelin, ii) illustrate the plasticity-associated signaling pathways of ag in the hippocampus, also involving memory resolution-enhancing neurogenesis, iii) elucidate how the peptide modulates neurotransmitter systems (glutamate, γ-aminobutyric acid, dopamine, serotonin), iv) clarify the role of ag in conditioned taste aversion, novelty learning and the formation of spatial, recognition, auditory fear, contextual fear and passive avoidance memories in the hippocampus and amygdala as well as v) solve the mystery behind ag, its impact on the 5-ht system, the recently established link to post-traumatic stress disorder and the either fear-suppressing or fear-potentiating effects under neutral and acutely stressed conditions or chronic stress, respectively. |
2022-11-11 |
2023-08-14 |
Not clear |
| Barbara Dos Anjos Rosário, Maria de Fátima SantanaNazaré, Daniel Vitor de Souza, Luciana Le Sueur-Maluf, Débora Estadella, Daniel Araki Ribeiro, Milena de Barros Vian. The influence of sex and reproductive cycle on cocaine-induced behavioral and neurobiological alterations: a review. Experimental brain research. 2022-10-20. PMID:36264315. |
these observations are related to the direct effects played by ovarian hormones (in particularly estradiol), in dopamine, but also in serotonin neurons, and in brain regions such as the tegmental area, the nucleus accumbens, the hypothalamus, the amygdala and the prefrontal cortex. |
2022-10-20 |
2023-08-14 |
Not clear |
| Olivia J Hon, Jeffrey F DiBerto, Christopher M Mazzone, Jonathan Sugam, Daniel W Bloodgood, J Andrew Hardaway, Mariya Husain, Alexis Kendra, Nora M McCall, Alberto J Lopez, Thomas L Kash, Emily G Lowery-Giont. Serotonin modulates an inhibitory input to the central amygdala from the ventral periaqueductal gray. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-08-23. PMID:35999277. |
serotonin modulates an inhibitory input to the central amygdala from the ventral periaqueductal gray. |
2022-08-23 |
2023-08-14 |
Not clear |
| Laura Durieux, Karine Herbeaux, Christopher Borcuk, Cécile Hildenbrand, Virginie Andry, Yannick Goumon, Alexandra Barbelivien, Chantal Mathis, Demian Bataglia, Monique Majchrzak, Lucas Lecourtie. Functional brain-wide network mapping during acute stress exposure in rats: Interaction between the lateral habenula and cortical, amygdalar, hypothalamic and monoaminergic regions. The European journal of neuroscience. 2022-08-22. PMID:35993349. |
it has been known for decades that the main structures engaged during the stress response are the medial prefrontal cortex, the amygdala, the hippocampus, the hypothalamus, the monoaminergic systems (noradrenaline, dopamine, serotonin), and the periaqueductal gray. |
2022-08-22 |
2023-08-14 |
rat |
| Ryo Yamamoto, Tetsufumi Ito, Takafumi Furuyama, Munenori Ono, Nobuo Kat. 5-HT and α-m-5-HT attenuate excitatory synaptic transmissions onto the lateral amygdala principal neurons via presynaptic 5-HT Biochemical and biophysical research communications. vol 624. 2022-08-06. PMID:35932576. |
5-ht and α-m-5-ht attenuate excitatory synaptic transmissions onto the lateral amygdala principal neurons via presynaptic 5-ht accumulating evidence suggests that the serotonergic (5-ht) system in the amygdala has significant effects on affective states. |
2022-08-06 |
2023-08-14 |
rat |
| Kanza M Khan, Gabrielle Bierlein-De La Rosa, Natalie Biggerstaff, Govindhasamy Pushpavathi Selvakumar, Ruixiang Wang, Suzanne Mason, Michael E Dailey, Catherine A Marcinkiewc. Adolescent ethanol drinking promotes hyperalgesia, neuroinflammation and serotonergic deficits in mice that persist into adulthood. Brain, behavior, and immunity. 2022-07-30. PMID:35907582. |
5-ht expression was also reduced in the thalamus, anterior cingulate cortex (acc) and amygdala as well as the lumbar dorsal horn of the spinal cord. |
2022-07-30 |
2023-08-14 |
mouse |
| Catharina S Hamann, Julian Bankmann, Hanna Mora Maza, Johannes Kornhuber, Iulia Zoicas, Angelika Schmitt-Böhre. Social Fear Affects Limbic System Neuronal Activity and Gene Expression. International journal of molecular sciences. vol 23. issue 15. 2022-07-28. PMID:35897794. |
sfc+ mice also showed alterations in the expression of npy and serotonin system-related genes in the paraventricular nucleus of the hypothalamus, basolateral amygdala, septum and dorsal raphe nucleus, but not in the dorsal hippocampus. |
2022-07-28 |
2023-08-14 |
mouse |
| Kei-Ichi Katayama, Naoko Morimura, Katsunori Kobayashi, Danielle Corbett, Takehito Okamoto, Veravej G Ornthanalai, Hayato Matsunaga, Wakako Fujita, Yoshifumi Matsumoto, Takumi Akagi, Tsutomu Hashikawa, Kazuyuki Yamada, Niall P Murphy, Soichi Nagao, Jun Arug. Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation. iScience. vol 25. issue 7. 2022-07-05. PMID:35789858. |
a serotonin metabolite was increased in the hippocampus and amygdala, and serotonergic neurons in the raphe nuclei were decreased in slitrk2 ko mice. |
2022-07-05 |
2023-08-14 |
mouse |
| Chunmei Lan, Congcong Liu, Keshuang Li, Zhiying Zhao, Jiaxin Yang, Yina Ma, Dirk Scheele, Yao Shuxia, Keith M Kendrick, Benjamin Becke. Oxytocinergic modulation of stress-associated amygdala-hippocampus pathways in humans is mediated by serotonergic mechanisms. The international journal of neuropsychopharmacology. 2022-06-20. PMID:35723242. |
against this background, the present pharmacological resting state fmri study aimed at determining whether effects of oxt on stress-associated amygdala intrinsic networks are mediated by 5-ht. |
2022-06-20 |
2023-08-14 |
Not clear |
| Natália Maria Simionato, Janaína da Silva Rocha-Lopes, Ricardo Borges Machado, Deborah Sucheck. Chronic rapid eye movement sleep restriction during juvenility has long-term effects on anxiety-like behaviour and neurotransmission of male Wistar rats. Pharmacology, biochemistry, and behavior. 2022-06-06. PMID:35662652. |
in a previous study, we showed that chronic sleep deprivation in juvenile-adolescent male rats led to increased anxiety-like behaviour and changes in noradrenaline and serotonin in the amygdala and hippocampus. |
2022-06-06 |
2023-08-14 |
rat |