| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yassine Ait Bali, Nour-Eddine Kaikai, Saadia Ba-M'hamed, Marco Sassoè-Pognetto, Maurizio Giustetto, Mohamed Benni. Anxiety and Gene Expression Enhancement in Mice Exposed to Glyphosate-Based Herbicide. Toxics. vol 10. issue 5. 2022-05-27. PMID:35622640. |
growing evidence demonstrates that serotonin (5-ht) depletion increases activity in the amygdala and medial prefrontal cortex (mpfc), ultimately leading to anxiety behavior. |
2022-05-27 |
2023-08-13 |
mouse |
| Tetsuo Ono, Kodai Hino, Tomoko Kimura, Yasuhiro Uchimura, Takashi Ashihara, Takako Higa, Hideto Kojima, Takashi Murakami, Jun Udagaw. Excessive folic acid intake combined with undernutrition during gestation alters offspring behavior and brain monoamine profiles. Congenital anomalies. 2022-05-09. PMID:35531602. |
these behavioral changes were accompanied by reduced dopamine in the prefrontal cortex (pfc), norepinephrine in the amygdala, and 5-hydroxytryptamine (5-ht) in the dorsal midbrain (dm), pfc, and amygdala where 5-ht neurons project from the dm. |
2022-05-09 |
2023-08-13 |
Not clear |
| Tetsuo Ono, Kodai Hino, Tomoko Kimura, Yasuhiro Uchimura, Takashi Ashihara, Takako Higa, Hideto Kojima, Takashi Murakami, Jun Udagaw. Excessive folic acid intake combined with undernutrition during gestation alters offspring behavior and brain monoamine profiles. Congenital anomalies. 2022-05-09. PMID:35531602. |
canonical discriminant analysis, including dopamine and dopac concentrations in the pfc, norepinephrine concentrations in the pfc, amygdala, and pons, and 5-ht and 5-hiaa concentrations in the amygdala and dm, correctly classified 73.5% of the offspring in con, ff, un, and un-ff groups. |
2022-05-09 |
2023-08-13 |
Not clear |
| Smriti Patodia, Alyma Somani, Joan Liu, Alice Cattaneo, Beatrice Paradiso, Maria Garcia, Muhammad Othman, Beate Diehl, Orrin Devinsky, James D Mills, Jackie Foong, Maria Tho. Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP. Brain pathology (Zurich, Switzerland). 2022-04-28. PMID:35478467. |
serotonin transporter in the temporal lobe, hippocampus and amygdala in sudep. |
2022-04-28 |
2023-08-13 |
Not clear |
| Naomichi Okamoto, Keita Watanabe, Hirofumi Tesen, Atsuko Ikenouchi, Ryohei Igata, Yuki Konishi, Tomoya Natsuyama, Rintaro Fujii, Shingo Kakeda, Taro Kishi, Nakao Iwata, Reiji Yoshimur. Volume of Amygdala Subregions and Plasma Levels of Brain-Derived Neurotrophic Factor and Cortisol in Patients with s/s Genotype of Serotonin Transporter Gene Polymorphism of First-Episode and Drug-Naive Major Depressive Disorder: An Exploratory Study. Neurology international. vol 14. issue 2. 2022-04-25. PMID:35466212. |
volume of amygdala subregions and plasma levels of brain-derived neurotrophic factor and cortisol in patients with s/s genotype of serotonin transporter gene polymorphism of first-episode and drug-naive major depressive disorder: an exploratory study. |
2022-04-25 |
2023-08-13 |
Not clear |
| Giancarlo Carli, Francesca Farabollin. Neuromediators and defensive responses including tonic immobility (TI): Brain areas and circuits involved. Progress in brain research. vol 271. issue 1. 2022-04-10. PMID:35397888. |
ti duration, in fact, decreases in rabbits following systemic serotonin administration and in guinea pigs following serotonin microinjection administration into the amygdala owing to the activation of fear-related gabaergic inhibitory mechanisms. |
2022-04-10 |
2023-08-13 |
human |
| Bingqian Zhou, Ge Jin, Xiaoqi Pang, Qi Mo, Jie Bao, Tiaotiao Liu, Jingyi Wu, Runxiang Xie, Xiang Liu, Jinghua Liu, Hongwei Yang, Xin Xu, Bangmao Wang, Hailong Ca. Lactobacillus rhamnosus GG colonization in early life regulates gut-brain axis and relieves anxiety-like behavior in adulthood. Pharmacological research. 2022-01-22. PMID:35065201. |
mechanically, lgg colonization activated epithelial growth factor receptor (egfr) and enhanced serotonin transporter (sert) expression and modulated serotonergic system in the intestine, and increased brain-derived neurotrophic factor and γ-aminobutyric acid receptor levels in the hippocampus and amygdala. |
2022-01-22 |
2023-08-13 |
mouse |
| Kirsten Szklany, Phillip A Engen, Ankur Naqib, Stefan J Green, Ali Keshavarzian, Alejandro Lopez Rincon, Cynthia J Siebrand, Mara A P Diks, Melanie van de Kaa, Johan Garssen, Leon M J Knippels, Aletta D Kranevel. Dietary Supplementation throughout Life with Non-Digestible Oligosaccharides and/or n-3 Poly-Unsaturated Fatty Acids in Healthy Mice Modulates the Gut-Immune System-Brain Axis. Nutrients. vol 14. issue 1. 2022-01-11. PMID:35011046. |
although the dietary effect on behaviour was limited, serotonin and serotonin metabolite levels in the amygdala were increased in the combination diet group. |
2022-01-11 |
2023-08-13 |
mouse |
| Claire Alexander, Maryam Vasef. Cannabidiol and the corticoraphe circuit in post-traumatic stress disorder. IBRO neuroscience reports. vol 11. 2021-12-11. PMID:34485973. |
acute cbd inhibits excess 5-ht release from drn to amygdala and releases anandamide (aea) onto amygdala inputs. |
2021-12-11 |
2023-08-13 |
Not clear |
| Mathilde Baudat, Anne R de Kort, Daniel L A van den Hove, Elbert A J Jooste. Early-life exposure to selective serotonin reuptake inhibitors: long-term effects on pain and affective comorbidities. The European journal of neuroscience. 2021-11-29. PMID:34841582. |
thus, the aim of this review is to understand how early-life selective serotonin reuptake inhibitor exposure alters the developing prefrontal cortex and amygdala, and thereby underlies the long-term changes in pain and its affective comorbidities in later life. |
2021-11-29 |
2023-08-13 |
Not clear |
| Mathilde Baudat, Anne R de Kort, Daniel L A van den Hove, Elbert A J Jooste. Early-life exposure to selective serotonin reuptake inhibitors: long-term effects on pain and affective comorbidities. The European journal of neuroscience. 2021-11-29. PMID:34841582. |
third, early-life selective serotonin reuptake inhibitor exposure alters serotonergic levels, transcription factors expression and brain derived neurotrophic factor levels, resulting in hyperconnectivity within the amygdala and the prefrontal cortex. |
2021-11-29 |
2023-08-13 |
Not clear |
| Mathilde Baudat, Anne R de Kort, Daniel L A van den Hove, Elbert A J Jooste. Early-life exposure to selective serotonin reuptake inhibitors: long-term effects on pain and affective comorbidities. The European journal of neuroscience. 2021-11-29. PMID:34841582. |
we conclude that early-life selective serotonin reuptake inhibitor exposure affects the maturation of prefrontal cortex and amygdala circuits and thereby enhances their anti-nociceptive inputs in the spinal cord. |
2021-11-29 |
2023-08-13 |
Not clear |
| Zoela Leon, Krishna Shah, Lauren S Bailey, Anushree N Karkhanis, Sunil Siroh. Patterned Feeding of a Hyper-Palatable Food (Oreo Cookies) Reduces Alcohol Drinking in Rats. Frontiers in behavioral neuroscience. vol 15. 2021-11-10. PMID:34744651. |
therefore, the present study evaluated the effects of patterned feeding of a hyper-palatable food (oreo cookies) on alcohol drinking as well as dopamine (da) and serotonin (5-ht) content in rat's mesocorticolimbic (medial-prefrontal cortex, orbitofrontal cortex, amygdala, and nucleus accumbens) circuitry. |
2021-11-10 |
2023-08-13 |
rat |
| Xiao Liu, Ya-Xin Sun, Chen-Chen Zhang, Xian-Qiang Zhang, Yue Zhang, Ting Wang, Yu-Nu Ma, Han Wang, Yun-Ai Su, Ji-Tao Li, Tian-Mei S. Vortioxetine attenuates the effects of early-life stress on depression-like behaviors and monoamine transporters in female mice. Neuropharmacology. vol 186. 2021-11-05. PMID:33485943. |
moreover, systemic 21-day treatment with vortioxetine, a novel multimodal antidepressant, successfully reversed depression-like behaviors and normalized some molecular changes, including that of the norepinephrine transporter in the medial prefrontal cortex, vesicular monoamine transporter 2 in nucleus accumbens core, and serotonin transporter in amygdala. |
2021-11-05 |
2023-08-13 |
mouse |
| Wenqian Wang, Ce Zhang, Yiqian Fan, Shumin Yue, Yunqi Yang, Rongxia Liu, Leiming Zhang, Tian Wang, Fenghua F. Dopamine receptor agonist rotigotine-loaded microspheres ameliorates sexual function deteriorated by fluoxetine in depression rats. ASN neuro. vol 13. 2021-11-02. PMID:34724850. |
the concentrations of 5-ht, dopamine, and norepinephrine were measured in the raphe nucleus and amygdala. |
2021-11-02 |
2023-08-13 |
rat |
| Amar Sarkar, Siobhán Harty, Katerina V-A Johnson, Andrew H Moeller, Rachel N Carmody, Soili M Lehto, Susan E Erdman, Robin I M Dunbar, Philip W J Burne. The role of the microbiome in the neurobiology of social behaviour. Biological reviews of the Cambridge Philosophical Society. vol 95. issue 5. 2021-10-25. PMID:32383208. |
these include the structure and function of regions of the 'social' brain (the amygdala, the prefrontal cortex, and the hippocampus) and the regulation of 'social' signalling molecules (glucocorticoids including corticosterone and cortisol, sex hormones including testosterone, oestrogens, and progestogens, neuropeptide hormones such as oxytocin and arginine vasopressin, and monoamine neurotransmitters such as serotonin and dopamine). |
2021-10-25 |
2023-08-13 |
human |
| Tempei Ikegame, Miki Bundo, Naohiro Okada, Yui Murata, Shinsuke Koike, Hiroko Sugawara, Takeo Saito, Masashi Ikeda, Keiho Owada, Masaki Fukunaga, Fumio Yamashita, Daisuke Koshiyama, Tatsunobu Natsubori, Norichika Iwashiro, Tatsuro Asai, Akane Yoshikawa, Fumichika Nishimura, Yoshiya Kawamura, Jun Ishigooka, Chihiro Kakiuchi, Tsukasa Sasaki, Osamu Abe, Ryota Hashimoto, Nakao Iwata, Hidenori Yamasue, Tadafumi Kato, Kiyoto Kasai, Kazuya Iwamot. Promoter Activity-Based Case-Control Association Study on SLC6A4 Highlighting Hypermethylation and Altered Amygdala Volume in Male Patients With Schizophrenia. Schizophrenia bulletin. vol 46. issue 6. 2021-10-25. PMID:32556264. |
associations between altered dna methylation of the serotonin transporter (5-htt)-encoding gene slc6a4 and early life adversity, mood and anxiety disorders, and amygdala reactivity have been reported. |
2021-10-25 |
2023-08-13 |
Not clear |
| Shirley Y Hill, Shuhui Wang, Howard Carter, Michael D McDermott, Nicholas Zezza, Scott Stiffle. Amygdala Volume in Offspring from Multiplex for Alcohol Dependence Families: The Moderating Influence of Childhood Environment and 5-HTTLPR Variation. Journal of alcoholism and drug dependence. vol Suppl 1. 2021-10-21. PMID:25285331. |
early childhood environment, genetic variation in the serotonin transporter-linked polymorphic region (5-httlpr) of the slca4 gene and allelic variation in the brain derived neurotrophic factor (bdnf) gene have each been reported to be related to volumetric differences in the temporal lobe especially the amygdala. |
2021-10-21 |
2023-08-13 |
Not clear |
| Emiliano Tesoro-Cruz, Leticia Manuel-Apolinar, Norma Oviedo, Sandra Orozco-Suárez, Minerva Crespo Ramírez, Vilma Carolina Bekker-Méndez, M Magdalena Aguirre-García, Sandra Angélica Rojas-Osornio, Vladimir Paredes-Cervantes, Miguel Pérez de la Mor. Increase of 5-HT levels is induced both in mouse brain and HEK-293 cells following their exposure to a non-viral tryptophan hydroxylase construct. Translational psychiatry. vol 11. issue 1. 2021-10-21. PMID:34625528. |
three days after the ocular administration of pires-hrgfp-1a-tph2-flag to mice, putative 5-ht production was significantly higher than in the control in both hypothalamus and amygdala, but not in the brainstem. |
2021-10-21 |
2023-08-13 |
mouse |
| Luanne H Hale, Maria C Tickerhoof, Adam S Smit. Chronic intranasal oxytocin reverses stress-induced social avoidance in female prairie voles. Neuropharmacology. vol 198. 2021-10-14. PMID:34461067. |
in males, serotonin 1a receptor binding was decreased in the basolateral amygdala and dorsal raphe nucleus starting at one week and four weeks post-defeat, respectively. |
2021-10-14 |
2023-08-13 |
Not clear |