| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Gurevich, P H Wu, P L Carle. Serotonin agonist and antagonist actions in hippocampal CA1 neurons. Canadian journal of physiology and pharmacology. vol 68. issue 5. 1990-06-28. PMID:2340447. |
the actions of serotonin (5-ht) and its putative agonists and antagonists were examined in vitro on hippocampal ca1 neurons using intracellular recordings, demonstrating that the cellular pharmacological effects can not necessarily be predicted from binding characteristics alone. |
1990-06-28 |
2023-08-11 |
Not clear |
| N Gurevich, P H Wu, P L Carle. Serotonin agonist and antagonist actions in hippocampal CA1 neurons. Canadian journal of physiology and pharmacology. vol 68. issue 5. 1990-06-28. PMID:2340447. |
spiperone, a nonspecific 5-ht antagonist, and ritanserin, a putative specific 5-ht2 receptor antagonist, depolarized ca1 neurons with little or no change in input resistance. |
1990-06-28 |
2023-08-11 |
Not clear |
| A Hirose, M Sasa, A Akaike, S Takaor. Inhibition of hippocampal CA1 neurons by 5-hydroxytryptamine, derived from the dorsal raphe nucleus and the 5-hydroxytryptamine1A agonist SM-3997. Neuropharmacology. vol 29. issue 2. 1990-05-30. PMID:1970426. |
inhibition of hippocampal ca1 neurons by 5-hydroxytryptamine, derived from the dorsal raphe nucleus and the 5-hydroxytryptamine1a agonist sm-3997. |
1990-05-30 |
2023-08-11 |
rat |
| S G Beck, P M Hallora. Imipramine alters beta-adrenergic, but not serotonergic, mediated responses in rat hippocampal pyramidal cells. Brain research. vol 504. issue 1. 1990-02-06. PMID:2557127. |
this study investigated acute and chronic effects of imipramine on intracellularly-recorded responses mediated by 5-ht and beta-adrenergic receptors on pyramidal cells from area ca1 of rat hippocampal slices maintained in vitro. |
1990-02-06 |
2023-08-11 |
rat |
| b' F Radja, G Daval, M B Emerit, M C Gallissot, M Hamon, D Verg\\xc3\\xa. Selective irreversible blockade of 5-hydroxytryptamine1A and 5-hydroxytryptamine1C receptor binding sites in the rat brain by 8-MeO-2\'-chloro-PAT: a quantitative autoradiographic study. Neuroscience. vol 31. issue 3. 1990-01-25. PMID:2531850.' |
a marked reduction (-50% to -75%) of [3h]8-oh-dpat and [125i]bh-8-meo-n-pat specific binding to 5-hydroxytryptamine1a sites in the hippocampus (ca1 area) and the dorsal raphe nucleus, and of [3h]5-hydroxytryptamine specific binding to 5-hydroxytryptamine1c sites in the choroid plexus was found in sections exposed to 1 microm 8-meo-2'-chloro-pat and then washed extensively. |
1990-01-25 |
2023-08-11 |
rat |
| M Segal, E C Azmitia, P M Whitaker-Azmiti. Physiological effects of selective 5-HT1a and 5-HT1b ligands in rat hippocampus: comparison to 5-HT. Brain research. vol 502. issue 1. 1990-01-04. PMID:2531014. |
the responses of ca1 neurons to topical application of serotonin (5-ht) and selective 5-ht1a and 5-ht1b agonists were examined with intracellular recording in the hippocampal slice. |
1990-01-04 |
2023-08-11 |
rat |
| S G Bec. 5-Carboxyamidotryptamine mimics only the 5-HT elicited hyperpolarization of hippocampal pyramidal cells via 5-HT1A receptor. Neuroscience letters. vol 99. issue 1-2. 1989-08-18. PMID:2748003. |
perfusion of the rat hippocampal slice in vitro by 5-hydroxytryptamine (5-ht) elicits 3 distinct actions recorded intracellularly from pyramidal cells in area ca1: a hyperpolarization, reduction in spike train elicited afterhyperpolarization (ahp) and depolarization. |
1989-08-18 |
2023-08-11 |
rat |
| J V Halliwell, E A Grov. 9-Amino-1,2,3,4-tetrahydroacridine (THA) blocks agonist-induced potassium conductance in rat hippocampal neurones. European journal of pharmacology. vol 163. issue 2-3. 1989-07-12. PMID:2721578. |
more sensitive to the action of tha was the outward k+ current activated in ca1 neurones by 5-ht, adenosine and baclofen. |
1989-07-12 |
2023-08-11 |
rat |
| b' Y Hong, K Krnjevi\\xc4\\x8. Serotonin blocks the facilitatory action of muscarinic and nicotinic agents in the hippocampus in vivo. Canadian journal of physiology and pharmacology. vol 67. issue 1. 1989-06-16. PMID:2653594.' |
the inhibitory effect of serotonin, released iontophoretically, on acetylcholine-induced facilitation of population spikes evoked by fimbria-commissural stimulation was studied in the ca1 region of rat hippocampus in vivo. |
1989-06-16 |
2023-08-11 |
rat |
| N Ihara, S Ueda, M Kawata, Y San. Immunohistochemical demonstration of serotonin-containing nerve fibers in the mammalian hippocampal formation. Acta anatomica. vol 132. issue 4. 1989-01-03. PMID:3057797. |
two peculiar observations should be stressed: (1) in the rat, the strata oriens and radiatum of ca2 and ca3 as well as the stratum lacunosum-moleculare displayed abundant serotonin fibers; (2) in the dog, abundant serotonin fibers were diffusely distributed in the ca1 field except for the stratum pyramidale and the most dense concentration of serotonin fibers was seen in the stratum oriens of ca3. |
1989-01-03 |
2023-08-11 |
rat |
| A Dresse, J Scuvée-Morea. Electrophysiological effects of tianeptine on rat locus coeruleus, raphe dorsalis, and hippocampus activity. Clinical neuropharmacology. vol 11 Suppl 2. 1988-12-20. PMID:3180117. |
the interaction of tianeptine and clomipramine with the response of ca1 cells to iontophoretically applied 5-ht or gaba was also investigated. |
1988-12-20 |
2023-08-11 |
rat |
| A Dresse, J Scuvée-Morea. Electrophysiological effects of tianeptine on rat locus coeruleus, raphe dorsalis, and hippocampus activity. Clinical neuropharmacology. vol 11 Suppl 2. 1988-12-20. PMID:3180117. |
the iontophoretic application of tianeptine did not modify the response of ca1 cells to 5-ht or gaba but decreased the recovery time after 5-ht and gaba. |
1988-12-20 |
2023-08-11 |
rat |
| A Dresse, J Scuvée-Morea. Electrophysiological effects of tianeptine on rat locus coeruleus, raphe dorsalis, and hippocampus activity. Clinical neuropharmacology. vol 11 Suppl 2. 1988-12-20. PMID:3180117. |
the iontophoretic application of clomipramine potentiated the response of ca1 cells to 5-ht but not to gaba and increased the recovery time after 5-ht and gaba. |
1988-12-20 |
2023-08-11 |
rat |
| N Roper. Inhibitory action of serotonin in CA1 hippocampal neurons in vitro. Neuroscience. vol 26. issue 1. 1988-10-20. PMID:2843792. |
inhibitory action of serotonin in ca1 hippocampal neurons in vitro. |
1988-10-20 |
2023-08-11 |
rat |
| N Roper. Inhibitory action of serotonin in CA1 hippocampal neurons in vitro. Neuroscience. vol 26. issue 1. 1988-10-20. PMID:2843792. |
the ionic mechanism of the inhibitory effect of serotonin was investigated in vitro in the ca1 region of the rat hippocampus by extra- and intracellular recordings. |
1988-10-20 |
2023-08-11 |
rat |
| G A Foster, M Schultzberg, F H Gage, A Björklund, T Hökfelt, A C Cuello, A A Verhofstad, T J Visser, P C Emso. Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system. II. Grafts to the hippocampus. Experimental brain research. vol 70. issue 2. 1988-07-29. PMID:2454837. |
outgrowth of 5ht-immunoreactive fibres was extensive, and displayed the typical pattern of 5ht innervation in the normal hippocampus-the densest plexuses were found in the dentate gyrus, with sparser networks in the ca1 and ca2 regions. |
1988-07-29 |
2023-08-11 |
rat |
| P H Wu, N Gurevich, P L Carle. Serotonin-1A receptor activation in hippocampal CA1 neurons by 8-hydroxy-2-(di-n-propylamino)tetralin, 5-methoxytryptamine and 5-hydroxytryptamine. Neuroscience letters. vol 86. issue 1. 1988-06-02. PMID:2966313. |
serotonin-1a receptor activation in hippocampal ca1 neurons by 8-hydroxy-2-(di-n-propylamino)tetralin, 5-methoxytryptamine and 5-hydroxytryptamine. |
1988-06-02 |
2023-08-11 |
Not clear |
| P H Wu, N Gurevich, P L Carle. Serotonin-1A receptor activation in hippocampal CA1 neurons by 8-hydroxy-2-(di-n-propylamino)tetralin, 5-methoxytryptamine and 5-hydroxytryptamine. Neuroscience letters. vol 86. issue 1. 1988-06-02. PMID:2966313. |
serotonin (5-ht) usually induced a slow hyperpolarization lasting several minutes on first drop-application onto ca1 neurons. |
1988-06-02 |
2023-08-11 |
Not clear |
| R Andrade, R A Nicol. Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro. The Journal of physiology. vol 394. 1988-05-12. PMID:3443977. |
the actions of serotonin (5-ht) on pyramidal cells of the ca1 region of the rat hippocampus were characterized using intracellular recording in in vitro brain slices. |
1988-05-12 |
2023-08-11 |
rat |
| R Andrade, R A Nicol. Novel anxiolytics discriminate between postsynaptic serotonin receptors mediating different physiological responses on single neurons of the rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 336. issue 1. 1987-10-22. PMID:2888027. |
since the buspirone induced hyperpolarization was also accompanied by a surmountable antagonism of 5-ht responses, these results indicate that buspirone behaves as a partial agonist at a subpopulation of 5-ht receptors in the ca1 region of the hippocampus. |
1987-10-22 |
2023-08-11 |
rat |