| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kevin Yen, Amanda Yaworski, Miguel Bussiere, Fang B. Pearls & Oy-sters: A Case Report of Holmes Tremor Due to Nigrostriatal Dopamine Disruption that Responded to Dopamine Replacement Therapy. Neurology. 2022-07-08. PMID:35803716. |
holmes tremor (ht), also known as midbrain, rubral, or cerebellar pathway outflow tremor, occurs due to disturbances of the cerebellothalamic pathway. |
2022-07-08 |
2023-08-14 |
Not clear |
| Kevin Yen, Amanda Yaworski, Miguel Bussiere, Fang B. Pearls & Oy-sters: A Case Report of Holmes Tremor Due to Nigrostriatal Dopamine Disruption that Responded to Dopamine Replacement Therapy. Neurology. 2022-07-08. PMID:35803716. |
this tremor is usually related to lesions in the midbrain peduncular region involving the superior cerebellar peduncle, red nucleus, and possibly the nigrostriatal circuitry. |
2022-07-08 |
2023-08-14 |
Not clear |
| Samuel S McAfee, Silu Zhang, Ping Zou, Heather M Conklin, Darcy Raches, Giles Robinson, Amar Gajjar, Raja Khan, Paul Klimo, Zoltan Patay, Matthew A Scoggin. Fastigial nuclei surgical damage and focal midbrain disruption implicate PAG survival circuits in cerebellar mutism syndrome. Neuro-oncology. 2022-07-05. PMID:35789275. |
fastigial nuclei surgical damage and focal midbrain disruption implicate pag survival circuits in cerebellar mutism syndrome. |
2022-07-05 |
2023-08-14 |
Not clear |
| Janna Krahe, Imis Dogan, Claire Didszun, Shahram Mirzazade, Alexa Haeger, Nadim Joni Shah, Ilaria A Giordano, Thomas Klockgether, Guillaume Madelin, Jörg B Schulz, Sandro Romanzetti, Kathrin Reet. Increased brain tissue sodium concentration in Friedreich ataxia: A multimodal MR imaging study. NeuroImage. Clinical. vol 34. 2022-05-02. PMID:35500368. |
compared to controls, patients showed reduced brain volume in the right cerebellar lobules i-v (difference in means: -0.039% of total intracranial volume [ticv]; cohen's d = 0.83), cerebellar white matter (wm) (-0.105%ticv; d = 1.16), and brainstem (-0.167%ticv; d = 1.22), including pons (-0.102%ticv; d = 1.00), medulla (-0.036%ticv; d = 1.72), and midbrain (-0.028%ticv; d = 1.05). |
2022-05-02 |
2023-08-13 |
Not clear |
| A Lee, S Klinkradt, P A McCombe, D V Po. Cloning of a new form of EAAT2/GLT-1 from human and rodent brains. Neuroscience letters. 2022-04-19. PMID:35439550. |
rt-pcr amplification using glt-1d specific primers confirmed expression of message in all brain regions examined (forebrain, midbrain, hindbrain and cerebellum) as well as spinal cord, astrocyte cultures, retina and peripheral tissues (liver, testis, small intestine and lung). |
2022-04-19 |
2023-08-13 |
human |
| Silvia Arber, Rui M Cost. Networking brainstem and basal ganglia circuits for movement. Nature reviews. Neuroscience. 2022-04-15. PMID:35422525. |
important networking components include broadcasting neurons in the cortex, cerebellar output neurons and midbrain dopaminergic neurons. |
2022-04-15 |
2023-08-13 |
Not clear |
| Débora Salles, Samara F Santino, Daniel Araki Ribeiro, Andréa C M Malinverni, João N Stával. The involvement of the MAPK pathway in pilocytic astrocytomas. Pathology, research and practice. vol 232. 2022-03-01. PMID:35231859. |
the molecular origin of pilocytic astrocytomas is related to alterations in the mapk pathway, which acts with several functions in the brain such as memory formation, pain perception, induction of cortical neurogenesis, and midbrain and cerebellum development. |
2022-03-01 |
2023-08-13 |
Not clear |
| Braeden A Terpou, Chantelle S Lloyd, Maria Densmore, Margaret C McKinnon, Jean Théberge, Richard W J Neufeld, Rakesh Jetly, Ruth A Laniu. Moral wounds run deep: exaggerated midbrain functional network connectivity across the default mode network in posttraumatic stress disorder. Journal of psychiatry & neuroscience : JPN. vol 47. issue 1. 2022-02-18. PMID:35177485. |
however, brainstem, midbrain and cerebellar systems are rarely integrated into the intrinsic connectivity networks; this is a critical oversight, because these systems display marked differences in people with ptsd and are thought to underlie strong moral emotions such as shame, guilt and betrayal. |
2022-02-18 |
2023-08-13 |
Not clear |
| Yoel Gofin, Tianyun Wang, Madelyn A Gillentine, Tiana M Scott, Aliska M Berry, Mahshid S Azamian, Casie Genetti, Pankaj B Agrawal, Jonathan Picker, Monica H Wojcik, Mauricio R Delgado, Sally A Lynch, Stephen W Scherer, Jennifer L Howe, Carlos A Bacino, Stephanie DiTroia, Grace E VanNoy, Anne O'Donnell-Luria, Seema R Lalani, William D Graf, Jill A Rosenfeld, Evan E Eichler, Rachel K Earl, Daryl A Scot. Delineation of a novel neurodevelopmental syndrome associated with PAX5 haploinsufficiency. Human mutation. 2022-01-30. PMID:35094443. |
pax5 is a transcription factor associated with abnormal posterior midbrain and cerebellum development in mice. |
2022-01-30 |
2023-08-13 |
mouse |
| Sebastian R Schreglmann, Derek Burke, Amit Batla, Nikola Kresojevic, Nicholas Wood, Simon Heales, Kailash P Bhati. Cerebellar and Midbrain Lysosomal Enzyme Deficiency in Isolated Dystonia. Movement disorders : official journal of the Movement Disorder Society. 2022-01-26. PMID:35080042. |
cerebellar and midbrain lysosomal enzyme deficiency in isolated dystonia. |
2022-01-26 |
2023-08-13 |
Not clear |
| Abdelaati El Khiat, Omar El Hiba, Lahcen Tamegart, Hanane Rais, Naima Fdil, Souad Sellami, Mohamed Ait El Mokhtar, Halima Gamran. Time dependent alteration of locomotor behavior in rat with acute liver failure induced cerebellar neuroinflammation and neuro-astroglial damage. Journal of chemical neuroanatomy. vol 119. 2021-12-11. PMID:34863855. |
hepatic and renal functions were assessed via various biochemical and histopathological examinations, while the cerebellum and the midbrain were examined using histology and immunohistochemistry for tyrosine hydroxylase (th), cyclooxygenase-2 (cox-2) and glial fibrillary acidic protein (gfap). |
2021-12-11 |
2023-08-13 |
rat |
| Sydney Fearnley, Reesha Raja, Jean-François Cloutie. Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Scientific reports. vol 11. issue 1. 2021-12-08. PMID:34599206. |
at one prenatal (e16) and two postnatal (p0 and p15) ages, we show that each iglon displays distinct expression patterns in the olfactory system, cerebral cortex, midbrain, cerebellum, spinal cord, and eye, indicating that they likely contribute to the wiring of specific neuronal circuitry. |
2021-12-08 |
2023-08-13 |
mouse |
| Yue Hui Lau, Ahmad Shahir Mawardi, Norzaini Rose Zain, Shanthi Viswanatha. Toluene-induced leukodystrophy from glue sniffing. Practical neurology. vol 21. issue 5. 2021-11-25. PMID:34039751. |
mr scan of the brain showed global cerebral and cerebellar atrophy with symmetrical t2-weighted hypointensities in the basal ganglia, thalami and midbrain. |
2021-11-25 |
2023-08-13 |
Not clear |
| Evangelos Anagnostou, Penelopi Koutsoudaki, Argyro Tountopoulou, Konstantinos Spengos, Sophia Vassilopoulo. Bedside Assessment of Vergence in Stroke Patients. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. vol 41. issue 4. 2021-11-18. PMID:32868577. |
given the widely distributed network of midbrain, pontine, cerebellar, and cortical areas involved in the neural control of vergence, one might expect various vergence deficits in stroke patients. |
2021-11-18 |
2023-08-13 |
Not clear |
| Tmader Alballa, Edward L Boone, Liangsuo Ma, Andrew Snyder, F Gerard Moelle. Exploring the relationship between white matter integrity, cocaine use and GAD polymorphisms using Bayesian Model Averaging. PloS one. vol 16. issue 7. 2021-11-03. PMID:34310624. |
gad1a was associated with more frontal white matter changes on its own but gad1b was associated with more midbrain and cerebellar changes as well as a greater increase in white matter changes in the context of chronic cocaine use. |
2021-11-03 |
2023-08-13 |
Not clear |
| Peng-Fei Zhang, Fan Ga. Neuroinflammation in Parkinson's disease: a meta-analysis of PET imaging studies. Journal of neurology. 2021-11-01. PMID:34724571. |
compared to hc, pd patients had elevated tspo levels in midbrain, putamen, anterior cingulate, posterior cingulate, thalamus, striatum, frontal, temporal, parietal, occipital, cortex, hippocampus, substantia nigra, pons, cerebellum, and caudate when using 1st-generation ligands. |
2021-11-01 |
2023-08-13 |
human |
| Ali Akay, Mete Ruksen, Burhanettin Uludag, Sertac Isleke. Treatment of intractable midbrain tremor with a pedinculopontine nucleus radiofrequency lesion. Turkish neurosurgery. 2021-10-19. PMID:34664699. |
midbrain tremor is usually seen in the pathologies of the thalamus, upper brainstem and cerebellum. |
2021-10-19 |
2023-08-13 |
Not clear |
| Isaac Deng, Michael D Wiese, Xin-Fu Zhou, Larisa Bobrovskay. The efficacy of systemic administration of lipopolysaccharide in modelling pre-motor Parkinson's disease in C57BL/6 mice. Neurotoxicology. vol 85. 2021-09-22. PMID:34097939. |
systemically administered lps induced increased glial markers gfap and iba-1 and oxidative stress marker 3-nitrotyrosine (3-nt) in the olfactory bulb, hippocampus, midbrain and cerebellum, and there were region specific changes in the expression of nfκb, il-1β, α-synuclein, th and bdnf proteins. |
2021-09-22 |
2023-08-13 |
mouse |
| Andrey Y Vinokurov, Olga A Stelmashuk, Polina A Ukolova, Evgeny A Zherebtsov, Andrey Y Abramo. Brain region specificity in reactive oxygen species production and maintenance of redox balance. Free radical biology & medicine. vol 174. 2021-09-09. PMID:34400296. |
using fluorescent indicators in live cell imaging and confocal microscopy, we have measured the rate of cytosolic and mitochondrial reactive oxygen species production, lipid peroxidation, and glutathione levels in cortex, hippocampus, midbrain, brain stem and cerebellum in acute slices of rat brain. |
2021-09-09 |
2023-08-13 |
rat |
| Alice Giotta Lucifero, Matias Baldoncini, Nunzio Bruno, Nicola Tartaglia, Antonio Ambrosi, Gian Luigi Marseglia, Renato Galzio, Alvaro Campero, Juha Hernesniemi, Sabino Luzz. Microsurgical Neurovascular Anatomy of the Brain: The Posterior Circulation (Part II). Acta bio-medica : Atenei Parmensis. vol 92. issue S4. 2021-09-06. PMID:34437362. |
the perforating arteries of the vertebrobasilar system derive from the pica, ba, aica, sca, and pca, and provide for a key contribution to the vascularization of the midbrain, pons, medulla oblongata, fourth ventricle, cerebellar and cerebral peduncles, thalamus, hypothalamus, subthalamus, posterior part of the internal capsule, and optic tract. |
2021-09-06 |
2023-08-13 |
Not clear |