| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kazuki Nagayasu, Shuji Kanek. Pharmacological approach for elucidating the role of dorsal raphe serotonin neurons in mood/emotion regulation. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 149. issue 1. 2017-04-07. PMID:28049879. |
pharmacological approach for elucidating the role of dorsal raphe serotonin neurons in mood/emotion regulation. |
2017-04-07 |
2023-08-13 |
Not clear |
| Danilo De Gregorio, Stefano Comai, Luca Posa, Gabriella Gobb. d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology. International journal of molecular sciences. vol 17. issue 11. 2017-03-30. PMID:27886063. |
lsd's mechanism of action is pleiotropic, primarily mediated by the serotonergic system in the dorsal raphe, binding the 5-ht |
2017-03-30 |
2023-08-13 |
Not clear |
| Catherine A Marcinkiewcz, Christopher M Mazzone, Giuseppe D'Agostino, Lindsay R Halladay, J Andrew Hardaway, Jeffrey F DiBerto, Montserrat Navarro, Nathan Burnham, Claudia Cristiano, Cayce E Dorrier, Gregory J Tipton, Charu Ramakrishnan, Tamas Kozicz, Karl Deisseroth, Todd E Thiele, Zoe A McElligott, Andrew Holmes, Lora K Heisler, Thomas L Kas. Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala. Nature. vol 537. issue 7618. 2017-03-14. PMID:27556938. |
here we show that 5-ht from the dorsal raphe nucleus (5-ht |
2017-03-14 |
2023-08-13 |
Not clear |
| Sam V Kaplan, Ryan A Limbocker, Rachel C Gehringer, Jenny L Divis, Gregory L Osterhaus, Maxwell D Newby, Michael J Sofis, David P Jarmolowicz, Brooke D Newman, Tiffany A Mathews, Michael A Johnso. Impaired Brain Dopamine and Serotonin Release and Uptake in Wistar Rats Following Treatment with Carboplatin. ACS chemical neuroscience. vol 7. issue 6. 2017-03-08. PMID:27145395. |
to investigate how chemotherapy treatment affects these systems, fast-scan cyclic voltammetry (fscv) at carbon-fiber microelectrodes was used to measure dopamine and serotonin release and uptake in coronal brain slices containing the striatum and dorsal raphe nucleus, respectively. |
2017-03-08 |
2023-08-13 |
rat |
| Peter Petschner, Gabriella Juhasz, Viola Tamasi, Csaba Adori, Laszlo Tothfalusi, Tomas Hökfelt, Gyorgy Bagd. Chronic venlafaxine treatment fails to alter the levels of galanin system transcripts in normal rats. Neuropeptides. vol 57. 2017-02-07. PMID:26891823. |
to answer this question we administered the selective serotonin and noradrenaline reuptake inhibitor (snri) venlafaxine (40mg/kg/day via osmotic minipumps) to normal rats and examined the levels of the transcripts for galanin and galr1-3 after a 3-week venlafaxine treatment in the dorsal raphe, hippocampus and frontal cortex. |
2017-02-07 |
2023-08-13 |
rat |
| Wenjuan Wang, Guangxia Cui, Biao Jin, Ke Wang, Xing Chen, Yu Sun, Lihua Qin, Wenpei Ba. Estradiol Valerate and Remifemin ameliorate ovariectomy-induced decrease in a serotonin dorsal raphe-preoptic hypothalamus pathway in rats. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 208. 2017-02-07. PMID:27562857. |
we determined the changes in serotonin expression in the dorsal raphe (dr) and preoptic anterior hypothalamus (poah) in ovariectomized rats. |
2017-02-07 |
2023-08-13 |
rat |
| Kaitlyn M Harding, Joseph S Lonstei. Extensive juvenile "babysitting" facilitates later adult maternal responsiveness, decreases anxiety, and increases dorsal raphe tryptophan hydroxylase-2 expression in female laboratory rats. Developmental psychobiology. vol 58. issue 4. 2017-01-17. PMID:26806471. |
we examined the effect of chronic exposure to pups during post-weaning juvenile life (days 22-36) on adult maternal responsiveness, anxiety-related behaviors, and dorsal raphe tryptophan hydroxylase-2 (tph2) and serotonin transporter (sert) levels in nulliparous rats. |
2017-01-17 |
2023-08-13 |
rat |
| Abdellatif Abbaoui, Omar E L Hiba, Halima Gamran. The neuronal basis of copper induced modulation of anxiety state in rat. Acta histochemica. vol 119. issue 1. 2017-01-11. PMID:27863709. |
our data report that cu enhanced 5ht innervation in the dorsal raphe nucleus (drn) together with a loss of th expression within the ventral tegmental area (vta), substantia nigra compacta (snc) and their subsequent outputs including the medial forebrain bundle (mfb) and striatum. |
2017-01-11 |
2023-08-13 |
rat |
| Inbar Zohar, Shai Shoham, Marta Weinstoc. Perinatal citalopram does not prevent the effect of prenatal stress on anxiety, depressive-like behaviour and serotonergic transmission in adult rat offspring. The European journal of neuroscience. vol 43. issue 4. 2016-12-13. PMID:26669896. |
the current study investigated whether administration of citalopram to pregnant rats could prevent anxiety and depressive-like behaviour induced by gestational stress in their offspring, and restore the expression of serotonin 1a autoreceptors in gabaergic interneurons in the medial prefrontal cortex and dorsal raphe nuclei in males, and of corticotropin-releasing factor type 2 receptors in gabaergic interneurons in the dorsal raphe nuclei in females. |
2016-12-13 |
2023-08-13 |
rat |
| Inbar Zohar, Shai Shoham, Marta Weinstoc. Perinatal citalopram does not prevent the effect of prenatal stress on anxiety, depressive-like behaviour and serotonergic transmission in adult rat offspring. The European journal of neuroscience. vol 43. issue 4. 2016-12-13. PMID:26669896. |
citalopram failed to restore the reduction in the expression of serotonin 1a autoreceptors in the prefrontal cortex of males and in corticotropin-releasing factor type 2 receptors in the dorsal raphe nuclei of females induced by prenatal stress. |
2016-12-13 |
2023-08-13 |
rat |
| Audrey Franceschi Biagioni, Rithiele Cristina de Oliveira, Ricardo de Oliveira, Juliana Almeida da Silva, Tayllon dos Anjos-Garcia, Camila Marroni Roncon, Alexandre Pinto Corrado, Hélio Zangrossi, Norberto Cysne Coimbr. 5-Hydroxytryptamine 1A receptors in the dorsomedial hypothalamus connected to dorsal raphe nucleus inputs modulate defensive behaviours and mediate innate fear-induced antinociception. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 3. 2016-12-13. PMID:26749090. |
5-hydroxytryptamine 1a receptors in the dorsomedial hypothalamus connected to dorsal raphe nucleus inputs modulate defensive behaviours and mediate innate fear-induced antinociception. |
2016-12-13 |
2023-08-13 |
Not clear |
| Audrey Franceschi Biagioni, Rithiele Cristina de Oliveira, Ricardo de Oliveira, Juliana Almeida da Silva, Tayllon dos Anjos-Garcia, Camila Marroni Roncon, Alexandre Pinto Corrado, Hélio Zangrossi, Norberto Cysne Coimbr. 5-Hydroxytryptamine 1A receptors in the dorsomedial hypothalamus connected to dorsal raphe nucleus inputs modulate defensive behaviours and mediate innate fear-induced antinociception. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 3. 2016-12-13. PMID:26749090. |
the dorsal raphe nucleus (drn) is an important brainstem source of 5-hydroxytryptamine (5-ht), and 5-ht plays a key role in the regulation of panic attacks. |
2016-12-13 |
2023-08-13 |
Not clear |
| A Inaba, Y Komori, Y Muroi, K Kinoshita, T Ishi. Neuropeptide Y signaling in the dorsal raphe nucleus inhibits male sexual behavior in mice. Neuroscience. vol 320. 2016-12-13. PMID:26868970. |
we next examined whether the dorsal raphe nucleus (drn), in which serotonergic (5-ht) neurons are distributed, is involved in npy-mediated inhibition of male sexual behavior. |
2016-12-13 |
2023-08-13 |
mouse |
| Kenichi Fukumoto, Michihiko Iijima, Shigeyuki Chak. The Antidepressant Effects of an mGlu2/3 Receptor Antagonist and Ketamine Require AMPA Receptor Stimulation in the mPFC and Subsequent Activation of the 5-HT Neurons in the DRN. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 4. 2016-11-08. PMID:26245499. |
given that the projections from the medial prefrontal cortex (mpfc) to the dorsal raphe nucleus (drn), where the majority of serotonin (5-ht) neurons exist, are reportedly involved in the antidepressant effects, in this study, we investigated using the forced swimming test (fst) of c57bl/6j male mice, the role of 5-ht neurons in the drn regulated by the mpfc-drn projections in the antidepressant effects of an mglu2/3 receptor antagonist, ly341495, and ketamine. |
2016-11-08 |
2023-08-13 |
mouse |
| Gregory S Parks, Deepti R Warrier, Lars Dittrich, Michael D Schwartz, Jeremiah B Palmerston, Thomas C Neylan, Stephen R Morairty, Thomas S Kilduf. The Dual Hypocretin Receptor Antagonist Almorexant is Permissive for Activation of Wake-Promoting Systems. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 4. 2016-11-08. PMID:26289145. |
we measured fos co-expression with markers for wake-promoting cell groups in the lateral hypothalamus (hcrt), tuberomammillary nuclei (histamine; ha), basal forebrain (acetylcholine; ach), dorsal raphe (serotonin; 5ht), and singly labeled fos(+) cells in the locus coeruleus (lc). |
2016-11-08 |
2023-08-13 |
rat |
| Nicholas A Courtney, Christopher P For. Mechanisms of 5-HT1A receptor-mediated transmission in dorsal raphe serotonin neurons. The Journal of physiology. vol 594. issue 4. 2016-11-04. PMID:26634643. |
mechanisms of 5-ht1a receptor-mediated transmission in dorsal raphe serotonin neurons. |
2016-11-04 |
2023-08-13 |
mouse |
| Nicholas A Courtney, Christopher P For. Mechanisms of 5-HT1A receptor-mediated transmission in dorsal raphe serotonin neurons. The Journal of physiology. vol 594. issue 4. 2016-11-04. PMID:26634643. |
in the dorsal raphe nucleus, it is known that serotonin release activates metabotropic 5-ht1a autoreceptors located on serotonin neurons that leads to an inhibition of firing through the activation of g-protein-coupled inwardly rectifying potassium channels. |
2016-11-04 |
2023-08-13 |
mouse |
| Nicholas A Courtney, Christopher P For. Mechanisms of 5-HT1A receptor-mediated transmission in dorsal raphe serotonin neurons. The Journal of physiology. vol 594. issue 4. 2016-11-04. PMID:26634643. |
these results indicate that evoked serotonin transmission in the dorsal raphe nucleus mediated by metabotropic 5-ht1a autoreceptors may occur via point-to-point synapses rather than by paracrine mechanisms. |
2016-11-04 |
2023-08-13 |
mouse |
| Chen Li, Lynn G Kirb. Effects of cocaine history on postsynaptic GABA receptors on dorsal raphe serotonin neurons in a stress-induced relapse model in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 1. 2016-10-27. PMID:26640169. |
effects of cocaine history on postsynaptic gaba receptors on dorsal raphe serotonin neurons in a stress-induced relapse model in rats. |
2016-10-27 |
2023-08-13 |
rat |
| Chen Li, Lynn G Kirb. Effects of cocaine history on postsynaptic GABA receptors on dorsal raphe serotonin neurons in a stress-induced relapse model in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 1. 2016-10-27. PMID:26640169. |
stressors and stress hormones can inhibit the dorsal raphe nucleus (drn)-5-ht system, which composes the majority of forebrain-projecting 5-ht. |
2016-10-27 |
2023-08-13 |
rat |