| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesca Liberatore, Nico Antenucci, Daniel Tortolani, Giada Mascio, Federico Fanti, Manuel Sergi, Giuseppe Battaglia, Valeria Bruno, Ferdinando Nicoletti, Mauro Maccarrone, Serena Notartomas. Targeting mGlu1 Receptors in the Treatment of Motor and Cognitive Dysfunctions in Mice Modeling Type 1 Spinocerebellar Ataxia. Cells. vol 11. issue 23. 2022-12-11. PMID:36497172. |
here, we report that otherwise healthy, 8-week-old sca1 mice showed a defect in spatial learning and memory associated with reduced protein levels of mglu1α receptors, the glun2b subunit of nmda receptors, and cannabinoid cb1 receptors in the hippocampus. |
2022-12-11 |
2023-08-14 |
mouse |
| Francesca Liberatore, Nico Antenucci, Daniel Tortolani, Giada Mascio, Federico Fanti, Manuel Sergi, Giuseppe Battaglia, Valeria Bruno, Ferdinando Nicoletti, Mauro Maccarrone, Serena Notartomas. Targeting mGlu1 Receptors in the Treatment of Motor and Cognitive Dysfunctions in Mice Modeling Type 1 Spinocerebellar Ataxia. Cells. vol 11. issue 23. 2022-12-11. PMID:36497172. |
this treatment also enhanced hippocampal levels of the endocannabinoid, anandamide, without changing the levels of 2-arachidonylglycerol. |
2022-12-11 |
2023-08-14 |
mouse |
| Jaqueline M Franzen, Isabel Werle, Felipe Vanz, Bruno Biscaia de Oliveira, Laura Maria Martins Nascimento, Francisco S Guimarães, Leandro J Bertogli. Cannabidiol attenuates fear memory expression in female rats via hippocampal 5-HT Neuropharmacology. 2022-11-05. PMID:36334768. |
in subsequent experiments, we investigated the estrous cycle effects and the contribution of dorsal hippocampus (dh) serotonin 1a (5-ht1a) and cannabinoid types 1 (cb1) and 2 (cb2) receptors to cbd-induced effects on memory retrieval/expression. |
2022-11-05 |
2023-08-14 |
human |
| Fouad Lemtiri-Chlieh, Eric S Levin. 2-AG and anandamide enhance hippocampal long-term potentiation Frontiers in cellular neuroscience. vol 16. 2022-10-10. PMID:36212685. |
2-ag and anandamide enhance hippocampal long-term potentiation it is widely accepted that exogenous cannabinoids can impair short-term memory and cognition in humans and other animals. |
2022-10-10 |
2023-08-14 |
mouse |
| Braulio Munoz, Brandon M Fritz, Fuqin Yin, Brady K Atwoo. HCN1 channels mediate mu opioid receptor long-term depression at insular cortex inputs to the dorsal striatum. The Journal of physiology. 2022-10-01. PMID:36181477. |
dorsal striatal cannabinoid long-term depression requires mtor signaling, similar to hippocampal cannabinoid long-term depression, but dorsal striatal mu opioid long-term depression does not require mtor signaling. |
2022-10-01 |
2023-08-14 |
Not clear |
| Prakash Nidadavolu, Andras Bilkei-Gorzo, Felix Effah, Este Leidmaa, Britta Schürmann, Moritz Berger, Laura Bindila, Matthias Schmid, Beat Lutz, Andreas Zimmer, Alexis Baile. Dynamic Changes in the Endocannabinoid System during the Aging Process: Focus on the Middle-Age Crisis. International journal of molecular sciences. vol 23. issue 18. 2022-09-23. PMID:36142165. |
endocannabinoid (ecb) signaling is markedly decreased in the hippocampus (hip) of aged mice, and the genetic deletion of the cannabinoid receptor type 1 (cb1) leads to an early onset of cognitive decline and age-related histological changes in the brain. |
2022-09-23 |
2023-08-14 |
mouse |
| Elisa Guma, Lani Cupo, Weiya Ma, Daniel Gallino, Luc Moquin, Alain Gratton, Gabriel A Devenyi, M Mallar Chakravart. Investigating the "two-hit hypothesis": Effects of prenatal maternal immune activation and adolescent cannabis use on neurodevelopment in mice. Progress in neuro-psychopharmacology & biological psychiatry. 2022-09-23. PMID:36150422. |
post-mortem assessment of cannabinoid (cb)1 and 2 receptor expressing cells was performed in altered regions identified by mri (anterior cingulate and somatosensory cortices, striatum, and hippocampus). |
2022-09-23 |
2023-08-14 |
mouse |
| Jaqueline M Franzen, Felipe Vanz, Isabel Werle, Francisco S Guimarães, Leandro J Bertogli. Cannabidiol impairs fear memory reconsolidation in female rats through dorsal hippocampus CB1 but not CB2 receptor interaction. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 64. 2022-09-01. PMID:36049316. |
moreover, the impairing effects of cbd on memory reconsolidation relied on the activation of cannabinoid type-1 but not type-2 receptors located in the ca1 subregion of the dorsal hippocampus. |
2022-09-01 |
2023-08-14 |
rat |
| Haley A Vecchiarelli, Maria Morena, Tiffany T Y Lee, Andrei S Nastase, Robert J Aukema, Kira D Leitl, J Megan Gray, Gavin N Petrie, Kristin J Tellez-Monnery, Matthew N Hil. Sex and stressor modality influence acute stress-induced dynamic changes in corticolimbic endocannabinoid levels in adult Sprague Dawley rats. Neurobiology of stress. vol 20. 2022-08-30. PMID:36039150. |
thirty minutes following stress onset, we excised the amygdala, hippocampus and medial prefrontal cortex, corticolimbic brain regions involved in the stress response, to measure endocannabinoid levels. |
2022-08-30 |
2023-08-14 |
rat |
| Jeremy J Watts, Elisa Guma, Sofia Chavez, Rachel F Tyndale, Ruth A Ross, Sylvain Houle, Alan A Wilson, Mallar Chakravarty, Pablo M Rusjan, Romina Mizrah. In vivo brain endocannabinoid metabolism is related to hippocampus glutamate and structure - a multimodal imaging study with PET, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-07-29. PMID:35906490. |
in vivo brain endocannabinoid metabolism is related to hippocampus glutamate and structure - a multimodal imaging study with pet, dysregulation of hippocampus glutamatergic neurotransmission and reductions in hippocampal volume have been associated with psychiatric disorders. |
2022-07-29 |
2023-08-14 |
Not clear |
| Jeremy J Watts, Elisa Guma, Sofia Chavez, Rachel F Tyndale, Ruth A Ross, Sylvain Houle, Alan A Wilson, Mallar Chakravarty, Pablo M Rusjan, Romina Mizrah. In vivo brain endocannabinoid metabolism is related to hippocampus glutamate and structure - a multimodal imaging study with PET, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-07-29. PMID:35906490. |
the endocannabinoid system modulates glutamate neurotransmission and brain development, including hippocampal remodeling. |
2022-07-29 |
2023-08-14 |
Not clear |
| Xue-Fei Hu, Hong Zhang, Ling-Ling Yu, Wen-Qiang Ge, Ou-Yang Zhan-Mu, Yan-Zhen Li, Chao Chen, Teng-Fei Hou, Hong-Chun Xiang, Yuan-Heng Li, Yang-Shuai Su, Xiang-Hong Jing, Jie Cao, Hui-Lin Pan, Wei He, Man L. Electroacupuncture Reduces Anxiety Associated With Inflammatory Bowel Disease By Acting on Cannabinoid CB1 Receptors in the Ventral Hippocampus in Mice. Frontiers in pharmacology. vol 13. 2022-07-25. PMID:35873560. |
electroacupuncture reduces anxiety associated with inflammatory bowel disease by acting on cannabinoid cb1 receptors in the ventral hippocampus in mice. |
2022-07-25 |
2023-08-14 |
mouse |
| Xue-Fei Hu, Hong Zhang, Ling-Ling Yu, Wen-Qiang Ge, Ou-Yang Zhan-Mu, Yan-Zhen Li, Chao Chen, Teng-Fei Hou, Hong-Chun Xiang, Yuan-Heng Li, Yang-Shuai Su, Xiang-Hong Jing, Jie Cao, Hui-Lin Pan, Wei He, Man L. Electroacupuncture Reduces Anxiety Associated With Inflammatory Bowel Disease By Acting on Cannabinoid CB1 Receptors in the Ventral Hippocampus in Mice. Frontiers in pharmacology. vol 13. 2022-07-25. PMID:35873560. |
it has been known that the ventral hippocampus (vhpc) and the cannabinoid type 1 receptors (cb1r) are involved in regulating anxiety and pain. |
2022-07-25 |
2023-08-14 |
mouse |
| Elena Hernández-Hernández, M Julia García-Fuste. Dose-Dependent Antidepressant-Like Effects of Cannabidiol in Aged Rats. Frontiers in pharmacology. vol 13. 2022-07-18. PMID:35847003. |
hippocampal cannabinoid receptors and cell proliferation were evaluated as potential molecular markers underlying cannabidiol's actions. |
2022-07-18 |
2023-08-14 |
rat |
| Tessa J Helman, John P Headrick, Jason N Peart, Nicolas J C Stapelber. Central and cardiac stress resiliences consistently linked to integrated immuno-neuroendocrine responses across stress models in male mice. The European journal of neuroscience. 2022-06-28. PMID:35763309. |
highly integrated expression of hpa axis, neuro-inflammatory, bdnf, monoamine, gaba, cannabinoid and opioid signalling genes was confirmed across conditions, and consistent/potentially causal correlations identified for: i) locomotor activity (noradrenaline, ghrelin; fc crhr1, tnfrsf1b, il33, nfkb1, maoa, gabra1; hippocampal il33); ii) thigmotaxis (adrenaline, leptin); iii) anxiety-like behaviour (adrenaline, leptin; fc tnfrsf1a; hippocampal il33); iv) depressive-like behaviour (ghrelin; fc/hippocampal s100a8); and v) cardiac stress-resistance (noradrenaline, leptin; fc il33, tnfrsf1b, htr1a, gabra1, gabrg2; hippocampal il33, tnfrsf1a, maoa, drd2). |
2022-06-28 |
2023-08-14 |
mouse |
| Majid Jafari-Sabet, Shiva Amiri, Helia Aghamiri, Navid Fatah. Cross state-dependent memory retrieval between cannabinoid CB1 and serotonergic 5-HT1A receptor agonists in the mouse dorsal hippocampus. Neurobiology of learning and memory. 2022-05-20. PMID:35595026. |
cross state-dependent memory retrieval between cannabinoid cb1 and serotonergic 5-ht1a receptor agonists in the mouse dorsal hippocampus. |
2022-05-20 |
2023-08-13 |
mouse |
| Marc Ten-Blanco, África Flores, Inmaculada Pereda-Pérez, Fabiana Piscitelli, Cristina Izquierdo-Luengo, Luigia Cristino, Julián Romero, Cecilia J Hillard, Rafael Maldonado, Vincenzo Di Marzo, Fernando Berrender. Amygdalar CB2 cannabinoid receptor mediates fear extinction deficits promoted by orexin-A/hypocretin-1. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 149. 2022-04-28. PMID:35477218. |
accordingly, increased 2-ag levels were observed in the amygdala and hippocampus of mice treated with oxa that do not extinguish fear, suggesting that high levels of this endocannabinoid are related to poor extinction. |
2022-04-28 |
2023-08-13 |
mouse |
| Krislei Scienza-Martin, Fernanda Nogueira Lotz, Querusche Klippel Zanona, Fabiana Santana-Kragelund, Ana Paula Crestani, Flávia Zacouteguy Boos, Maria Elisa Calcagnotto, Jorge Alberto Quillfeld. Memory consolidation depends on endogenous hippocampal levels of anandamide: CB1 and M4, but possibly not TRPV1 receptors mediate AM404 effects. Neuroscience. 2022-04-18. PMID:35436517. |
the endocannabinoid system is involved in the fine-tuning of local synaptic plasticity in the hippocampus during the initial steps of memory formation/transformation. |
2022-04-18 |
2023-08-13 |
rat |
| Mirmohammadali Mirramezani Alizamini, Yonghui Li, Jian-Jun Zhang, Jing Liang, Abbas Haghparas. Endocannabinoids and addiction memory: Relevance to Methamphetamine/Morphine Abuse. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 2022-02-09. PMID:35137652. |
also, the amygdala, hippocampus, and prefrontal cortex are three important brain regions that participate in both drug addiction and memory task processes, and endocannabinoid neurotransmission have been investigated. |
2022-02-09 |
2023-08-13 |
Not clear |
| David De Sa Nogueira, Romain Bourdy, Rafael Alcala-Vida, Dominique Filliol, Virginie Andry, Yannick Goumon, Jean Zwiller, Pascal Romieu, Karine Merienne, Mary C Olmstead, Katia Befor. Hippocampal Cannabinoid 1 Receptors Are Modulated Following Cocaine Self-administration in Male Rats. Molecular neurobiology. 2022-01-15. PMID:35032317. |
hippocampal cannabinoid 1 receptors are modulated following cocaine self-administration in male rats. |
2022-01-15 |
2023-08-13 |
rat |