| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yiyun Ding, Hongxia Zhang, Zhaojun Liu, Qiuping Li, Yujiao Guo, Ye Chen, Yue Chang, Hongyan Cu. Carnitine palmitoyltransferase 1 (CPT1) alleviates oxidative stress and apoptosis of hippocampal neuron in response to beta-Amyloid peptide fragment Aβ Bioengineered. vol 12. issue 1. 2021-09-27. PMID:34424821. |
carnitine palmitoyltransferase 1 (cpt1) alleviates oxidative stress and apoptosis of hippocampal neuron in response to beta-amyloid peptide fragment aβ cpt1c, which is expressed in hippocampus, influences ceramide level, endogenous cannabinoid and oxidation process, as well as plays an important role in various brain functions such as learning. |
2021-09-27 |
2023-08-13 |
Not clear |
| Thomas Heinbockel, Naina Bhatia-Dey, Vonnie D C Shield. Endocannabinoid-mediated neuromodulation in the main olfactory bulb at the interface of environmental stimuli and central neural processing. The European journal of neuroscience. 2021-09-17. PMID:33724578. |
our current understanding of the response dynamics of the endocannabinoid system is based in large part on research advances in limbic system areas, such as the hippocampus and the amygdala. |
2021-09-17 |
2023-08-13 |
human |
| Xiaoru Dong, Dingang Zhang, Rongzhe Zhu, Xiaochen Liu, Yonghong Ye, Yan Jian. Spatio-temporal effects of acute alcohol intoxication on endocannabinoid system in rat brain and blood. Alcohol (Fayetteville, N.Y.). vol 88. 2021-09-15. PMID:32738384. |
our results indicate that acute alcohol consumption inhibits endocannabinoid (ecb) production in the blood and in the prefrontal cortex of the brain, whereas the reverse was observed in the brain regions of the hippocampus and striatum. |
2021-09-15 |
2023-08-13 |
human |
| Shaghayegh Navabpour, Ameneh Rezayof, Zahra Ghasemzade. Activation of VTA/CeA/mPFC cannabinoid CB1 receptors induced conditioned drug effects via interacting with hippocampal CAMKII-CREB-BDNF signaling pathway in rats. European journal of pharmacology. vol 909. 2021-09-10. PMID:34389313. |
activation of vta/cea/mpfc cannabinoid cb1 receptors induced conditioned drug effects via interacting with hippocampal camkii-creb-bdnf signaling pathway in rats. |
2021-09-10 |
2023-08-13 |
rat |
| Qi He, Lin Jiang, Yi Zhang, Hao Yang, Chun-Ni Zhou, Yu-Han Xie, Yan-Min Luo, Shan-Shan Zhang, Lin Zhu, Yi-Jing Guo, Yu-Hui Deng, Xin Liang, Qian Xiao, Lei Zhang, Jing Tang, Du-Juan Huang, Yu-Ning Zhou, Xiao-Yun Dou, Feng-Lei Chao, Yong Tan. Anti-LINGO-1 antibody ameliorates cognitive impairment, promotes adult hippocampal neurogenesis, and increases the abundance of CB1R-rich CCK-GABAergic interneurons in AD mice. Neurobiology of disease. vol 156. 2021-09-03. PMID:34044148. |
behavioral, stereology, immunohistochemistry and immunofluorescence analyses revealed that the anti-lingo-1 antibody significantly improved the cognitive abilities, promoted adult hippocampal neurogenesis (ahn), decreased the amyloid beta (aβ) deposition, enlarged the hippocampal volume, and increased the numbers of total neurons and gabaergic interneurons, including gabaergic and cck-gabaergic interneurons rich in cannabinoid type 1 receptor (cb1r), in the hippocampus of ad mice. |
2021-09-03 |
2023-08-13 |
mouse |
| Kosuke Kataoka, Andras Bilkei-Gorzo, Chihiro Nozaki, Akinobu Togo, Keiichiro Nakamura, Keisuke Ohta, Andreas Zimmer, Toru Asah. Age-dependent Alteration in Mitochondrial Dynamics and Autophagy in Hippocampal Neuron of Cannabinoid CB1 Receptor-deficient Mice. Brain research bulletin. vol 160. 2021-08-31. PMID:32294520. |
age-dependent alteration in mitochondrial dynamics and autophagy in hippocampal neuron of cannabinoid cb1 receptor-deficient mice. |
2021-08-31 |
2023-08-13 |
mouse |
| Sari Goldstein Ferber, Viviana Trezza, Aron Welle. Early life stress and development of the endocannabinoid system: A bidirectional process in programming future coping. Developmental psychobiology. vol 63. issue 2. 2021-08-25. PMID:31849055. |
specifically, exposure to early stress results in bidirectional changes in anandamide and 2-ag tissue levels within the amygdala and hippocampus and reduces hippocampal endocannabinoid function at puberty. |
2021-08-25 |
2023-08-13 |
Not clear |
| Dingang Zhang, Xiaochen Liu, Xiaoru Dong, Rongzhe Zhu, Jieqing Jiang, Yonghong Ye, Yan Jian. Cannabinoid 1 Receptor Antagonists Play a Neuroprotective Role in Chronic Alcoholic Hippocampal Injury Related to Pyroptosis Pathway. Alcoholism, clinical and experimental research. vol 44. issue 8. 2021-08-16. PMID:32524615. |
cannabinoid 1 receptor antagonists play a neuroprotective role in chronic alcoholic hippocampal injury related to pyroptosis pathway. |
2021-08-16 |
2023-08-13 |
mouse |
| Jordan S Farrell, Roberto Colangeli, Ao Dong, Antis G George, Kwaku Addo-Osafo, Philip J Kingsley, Maria Morena, Marshal D Wolff, Barna Dudok, Kaikai He, Toni A Patrick, Keith A Sharkey, Sachin Patel, Lawrence J Marnett, Matthew N Hill, Yulong Li, G Campbell Teskey, Ivan Soltes. In vivo endocannabinoid dynamics at the timescale of physiological and pathological neural activity. Neuron. vol 109. issue 15. 2021-08-13. PMID:34352214. |
using novel imaging approaches in awake behaving mice, we now demonstrate that the endocannabinoid 2-arachidonoylglycerol, not anandamide, is dynamically coupled to hippocampal neural activity with high spatiotemporal specificity. |
2021-08-13 |
2023-08-13 |
mouse |
| R Ya Gordon, I B Mikheeva, L V Shubina, S S Khutsian, V F Kitchigin. Kainate-Induced Degeneration of Hippocampal Neurons. Protective Effect of Activation of the Endocannabinoid System. Bulletin of experimental biology and medicine. vol 171. issue 3. 2021-08-04. PMID:34297297. |
activation of the endocannabinoid system induced by intracerebral injection of urb597, an inhibitor of degradation of endocannabinoid anandamide, protected the normal structure of the hippocampus and prevented neuronal damage and death induced by ka. |
2021-08-04 |
2023-08-13 |
Not clear |
| Thomas Heinbockel, Alex Straike. Cannabinoids Regulate Sensory Processing in Early Olfactory and Visual Neural Circuits. Frontiers in neural circuits. vol 15. 2021-08-04. PMID:34305536. |
while the function of the endocannabinoid system is understood fairly well in limbic structures such as the hippocampus and the amygdala, this signaling system is less well understood in the olfactory pathway and the visual system. |
2021-08-04 |
2023-08-13 |
Not clear |
| Giulia Abate, Daniela Uberti, Simone Tambar. Potential and Limits of Cannabinoids in Alzheimer's Disease Therapy. Biology. vol 10. issue 6. 2021-07-05. PMID:34204237. |
since the endocannabinoid system (ecs) is highly expressed in the hippocampus and cortex, cannabis use/abuse has often been associated with memory and learning dysfunction in vulnerable individuals. |
2021-07-05 |
2023-08-13 |
Not clear |
| Giulia Abate, Daniela Uberti, Simone Tambar. Potential and Limits of Cannabinoids in Alzheimer's Disease Therapy. Biology. vol 10. issue 6. 2021-07-05. PMID:34204237. |
however, the latest findings in ad rodent models have shown promising effects of cannabinoids in reducing amyloid plaque deposition and stimulating hippocampal neurogenesis. |
2021-07-05 |
2023-08-13 |
Not clear |
| Willian Lazarini-Lopes, Raquel A Do Val-da Silva, Rui M P da Silva-Júnior, Gleice K Silva-Cardoso, Christie R A Leite-Panissi, João P Leite, Norberto Garcia-Cairasc. Chronic cannabidiol (CBD) administration induces anticonvulsant and antiepileptogenic effects in a genetic model of epilepsy. Epilepsy & behavior : E&B. vol 119. 2021-06-29. PMID:33887676. |
chronic seizures increased cannabinoid receptors type 1 (cb1r) immunostaining in the hippocampus and the bla, while cbd administration prevented changes in cb1r expression induced by the auk. |
2021-06-29 |
2023-08-13 |
rat |
| David de Sa Nogueira, Romain Bourdy, Dominique Filliol, Gaëlle Awad, Virginie Andry, Yannick Goumon, Mary C Olmstead, Katia Befor. Binge sucrose-induced neuroadaptations: A focus on the endocannabinoid system. Appetite. vol 164. 2021-06-28. PMID:33864862. |
importantly, this group also exhibited alterations in ecs transcripts and endocannabinoid levels in brain reward regions, including an increase in cannabinoid receptor 1 (cb1r) mrna in the nucleus accumbens as well as changes in endocannabinoid levels in the prefrontal cortex and hippocampus. |
2021-06-28 |
2023-08-13 |
rat |
| Wan-Ting Liao, Chao-Lin Chang, Yi-Tse Hsia. Activation of cannabinoid type 1 receptors decreases the synchronization of local field potential oscillations in the hippocampus and entorhinal cortex and prolongs the interresponse time during a differential-reinforcement-of-low-rate task. The European journal of neuroscience. vol 52. issue 10. 2021-06-21. PMID:32510690. |
activation of cannabinoid type 1 receptors decreases the synchronization of local field potential oscillations in the hippocampus and entorhinal cortex and prolongs the interresponse time during a differential-reinforcement-of-low-rate task. |
2021-06-21 |
2023-08-13 |
human |
| Musa Sami, Amanda Worker, Marco Colizzi, Luciano Annibale, Debasis Das, Marlene Kelbrick, Savitha Eranti, Tracy Collier, Chidimma Onyejiaka, Aisling O'Neill, David Lythgoe, Philip McGuire, Steve C R Williams, Matthew J Kempton, Sagnik Bhattacharyy. Association of cannabis with glutamatergic levels in patients with early psychosis: Evidence for altered volume striatal glutamate relationships in patients with a history of cannabis use in early psychosis. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32317625. |
we examined relationships in regions with known high cannabinoid 1 receptor (cb1r) expression (grey matter, cortex, hippocampus, amygdala) and low expression (white matter, ventricles, brainstem) to caudate glutamine+glutamate (glx). |
2021-06-18 |
2023-08-13 |
human |
| Yanpei Wang, Chenyi Zuo, Wenchao Wang, Qinfang Xu, Lei Ha. Reduction in hippocampal volumes subsequent to heavy cannabis use: a 3-year longitudinal study. Psychiatry research. vol 295. 2021-06-15. PMID:33261923. |
cannabis exposure is related to neuroanatomical changes in brain regions rich in cannabinoid receptors, such as the hippocampus. |
2021-06-15 |
2023-08-13 |
Not clear |
| Kyle R Jensen, Coralie Berthoux, Kaoutsar Nasrallah, Pablo E Castill. Multiple cannabinoid signaling cascades powerfully suppress recurrent excitation in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 4. 2021-06-09. PMID:33468648. |
multiple cannabinoid signaling cascades powerfully suppress recurrent excitation in the hippocampus. |
2021-06-09 |
2023-08-13 |
Not clear |
| Francisco Navarrete, María Salud García-Gutiérrez, Ani Gasparyan, Amaya Austrich-Olivares, Jorge Manzanare. Role of Cannabidiol in the Therapeutic Intervention for Substance Use Disorders. Frontiers in pharmacology. vol 12. 2021-06-08. PMID:34093179. |
furthermore, a special section of the review is focused on the neurobiological mechanisms that might be underlying the 'anti-addictive' action of cbd through the regulation of dopaminergic, opioidergic, serotonergic, and endocannabinoid systems as well as hippocampal neurogenesis. |
2021-06-08 |
2023-08-13 |
Not clear |