| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aparecida Vines, Ana Marcia Delattre, Marcelo M S Lima, Laís Soares Rodrigues, Deborah Suchecki, Ricardo B Machado, Sergio Tufik, Sofia I R Pereira, Sílvio M Zanata, Anete Curte Ferra. The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740919. |
in experiment 2, cortical and hippocampal contents of bdnf, 5-ht, dopamine (da) and its metabolites, 5-hydroxyindoleacetic acid (5-hiaa), and 3,4-dihydroxyphenylacetic acid (dopac), were determined in animals subjected to the same protocol. |
2012-08-13 |
2023-08-12 |
rat |
| Aparecida Vines, Ana Marcia Delattre, Marcelo M S Lima, Laís Soares Rodrigues, Deborah Suchecki, Ricardo B Machado, Sergio Tufik, Sofia I R Pereira, Sílvio M Zanata, Anete Curte Ferra. The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740919. |
in 90 day-old rats, 5-ht content in the hippocampus was increased, whereas 5-hiaa formation was diminished in the fish oil group. |
2012-08-13 |
2023-08-12 |
rat |
| Aparecida Vines, Ana Marcia Delattre, Marcelo M S Lima, Laís Soares Rodrigues, Deborah Suchecki, Ricardo B Machado, Sergio Tufik, Sofia I R Pereira, Sílvio M Zanata, Anete Curte Ferra. The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740919. |
we suggest the occurrence of a reciprocal involvement of 5-ht(1a) receptors activation and the hippocampal bdnf-increased expression mediated by fish oil supplementation. |
2012-08-13 |
2023-08-12 |
rat |
| Galina T Shishkina, Tatyana S Kalinina, Inna V Berezova, Nikolay N Dygal. Stress-induced activation of the brainstem Bcl-xL gene expression in rats treated with fluoxetine: correlations with serotonin metabolism and depressive-like behavior. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740920. |
mechanisms underlying stress-induced depression and antidepressant drug action were shown to involve alterations in serotonergic (5-ht) neurotransmission and expression of genes coding for proteins associated with neurotrophic signaling pathways and cell-survival in the hippocampus and cortex. |
2012-08-13 |
2023-08-12 |
rat |
| David Petrik, Diane C Lagace, Amelia J Eisc. The neurogenesis hypothesis of affective and anxiety disorders: are we mistaking the scaffolding for the building? Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21945290. |
the hypothesis was established in the 1990s but was built on a broad foundation of earlier research on the hippocampus, serotonin and mdd. |
2012-08-13 |
2023-08-12 |
mouse |
| Julie Espallergues, Takayoshi Mamiya, Monique Vallée, Takenao Koseki, Toshitaka Nabeshima, Jamal Temsamani, Claude Laruelle, Tangui Mauric. The antidepressant-like effects of the 3β-hydroxysteroid dehydrogenase inhibitor trilostane in mice is related to changes in neuroactive steroid and monoamine levels. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21945799. |
trilostane (25 mg/kg) treatment significantly increased 5-ht and (-)-norepinephrine (ne) turnovers in the hippocampus, an effect likely related to its antidepressant action. |
2012-08-13 |
2023-08-12 |
mouse |
| Malgorzata Elzbieta Zajda, Pawel Krzascik, Martin Hill, Maria Dorota Majewsk. Psychomotor and rewarding properties of the neurosteroids dehydroepiandrosterone sulphate and androsterone: effects on monoamine and steroid metabolism. Acta neurobiologiae experimentalis. vol 72. issue 1. 2012-08-09. PMID:22508085. |
dheas reduced the hippocampal dopamine level, increased striatal homovanilic acid (hva) and decreased the striatal serotonin concentrations. |
2012-08-09 |
2023-08-12 |
rat |
| Malgorzata Elzbieta Zajda, Pawel Krzascik, Martin Hill, Maria Dorota Majewsk. Psychomotor and rewarding properties of the neurosteroids dehydroepiandrosterone sulphate and androsterone: effects on monoamine and steroid metabolism. Acta neurobiologiae experimentalis. vol 72. issue 1. 2012-08-09. PMID:22508085. |
androsterone did not affect dopamine levels or turnover, but increased noradrenaline concentration and serotonin turnover in the hippocampus. |
2012-08-09 |
2023-08-12 |
rat |
| Erica Y Shen, Syed F Ali, Jerrold S Meye. Chronic administration of THC prevents the behavioral effects of intermittent adolescent MDMA administration and attenuates MDMA-induced hyperthermia and neurotoxicity in rats. Neuropharmacology. vol 61. issue 8. 2012-08-01. PMID:21763331. |
thc additionally attenuated mdma -induced decreases in 5-ht levels and in sert binding in the frontal cortex, parietal cortex, and striatum, but not in the hippocampus. |
2012-08-01 |
2023-08-12 |
rat |
| Carmela M Reichel, Lauren A Ramsey, Marek Schwendt, Jacqueline F McGinty, Ronald E Se. Methamphetamine-induced changes in the object recognition memory circuit. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22115899. |
subsequently, transporters for serotonin (sert) and norepinephrine (net) were quantified using western blot in tissue obtained from the hippocampus, perirhinal cortex, and prefrontal cortex. |
2012-07-27 |
2023-08-12 |
human |
| L Costa, C Trovato, S A Musumeci, M V Catania, L Cirann. 5-HT(1A) and 5-HT(7) receptors differently modulate AMPA receptor-mediated hippocampal synaptic transmission. Hippocampus. vol 22. issue 4. 2012-07-24. PMID:21538661. |
5-ht(1a) and 5-ht(7) receptors differently modulate ampa receptor-mediated hippocampal synaptic transmission. |
2012-07-24 |
2023-08-12 |
mouse |
| L Costa, C Trovato, S A Musumeci, M V Catania, L Cirann. 5-HT(1A) and 5-HT(7) receptors differently modulate AMPA receptor-mediated hippocampal synaptic transmission. Hippocampus. vol 22. issue 4. 2012-07-24. PMID:21538661. |
we have studied the effects of 5-ht(1a) and 5-ht(7) serotonin receptor activation in hippocampal ca3-ca1 synaptic transmission using patch clamp on mouse brain slices. |
2012-07-24 |
2023-08-12 |
mouse |
| Katsuyoshi Mizukami, Masanori Ishikawa, Hiroyasu Akatsu, Eric E Abrahamson, Milos D Ikonomovic, Takashi Asad. An immunohistochemical study of the serotonin 1A receptor in the hippocampus of subjects with Alzheimer's disease. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 31. issue 5. 2012-07-23. PMID:21269332. |
an immunohistochemical study of the serotonin 1a receptor in the hippocampus of subjects with alzheimer's disease. |
2012-07-23 |
2023-08-12 |
human |
| R D Creech, Q Li, G A Carrasco, L D Van de Kar, N A Mum. Estradiol induces partial desensitization of serotonin 1A receptor signaling in the paraventricular nucleus of the hypothalamus and alters expression and interaction of RGSZ1 and Gαz. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22251927. |
a 55 kd membrane-associate rgsz1 protein was greatly increased in the pvn and rest of the hypothalamus and moderately increased in the dorsal hippocampus and amygdala after eb treatment as well as after an acute dose of a 5-ht(1a) receptor agonist. |
2012-07-23 |
2023-08-12 |
Not clear |
| P Panther, S Nullmeier, H Dobrowolny, H Schwegler, R Wol. CPB-K mice a mouse model of schizophrenia? Differences in dopaminergic, serotonergic and behavioral markers compared to BALB/cJ mice. Behavioural brain research. vol 230. issue 1. 2012-07-23. PMID:22454846. |
our results can be summarized as follows: compared to balb/cj, cpb-k mice showed:(1) significantly reduced traveling distance and number of contacts in social interaction test, (2) differences in the number of serotonin transporter-immunoreactive neurons and volume of raphe nuclei and a lower serotonergic fiber density in the ventral and dorsal hippocampal subfields ca1 and ca3, (3) no alterations of dopaminergic markers like neuron number, neuron density and volume in subregions of substantia nigra and ventral tegmental area, but a significantly higher dopaminergic fiber density in the dorsal hippocampus, the ventral hippocampus of ca1 and gyrus dentatus, (4) no significant differences in serotonergic and dopaminergic fiber densities in the amygdala.based on our results and previous studies, cpb-k mice compared to balb/cj may serve as an important model to understand the interaction of the serotonergic and dopaminergic system and their impact on sensorimotor gating and cognitive function as related to neuropsychiatric disorders like schizophrenia. |
2012-07-23 |
2023-08-12 |
mouse |
| Simon Trent, Tommaso Cassano, Gaurav Bedse, Obah A Ojarikre, Trevor Humby, William Davie. Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 5. 2012-07-20. PMID:22189290. |
high performance liquid chromatography analysis of monoamine levels in wild type and 39,x(y)*o brain tissue regions (the frontal cortex, striatum, thalamus, hippocampus, and cerebellum) revealed significantly higher levels of 5-hydroxytryptamine (5-ht) in the striatum and hippocampus of 39,x(y)*o mice. |
2012-07-20 |
2023-08-12 |
mouse |
| Simon Trent, Tommaso Cassano, Gaurav Bedse, Obah A Ojarikre, Trevor Humby, William Davie. Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 5. 2012-07-20. PMID:22189290. |
significant correlations between hippocampal 5-ht levels and pr performance, and between striatal 5-ht levels and locomotor activity strongly implicate regionally-specific perturbations of the 5-ht system as a neurobiological candidate for behavioral differences between 40,xy and 39,x(y)*o mice. |
2012-07-20 |
2023-08-12 |
mouse |
| Isabella Peruga, Silvia Hartwig, Doron Merkler, Jan Thöne, Bernhard Hovemann, Georg Juckel, Ralf Gold, Ralf A Linke. Endogenous ciliary neurotrophic factor modulates anxiety and depressive-like behavior. Behavioural brain research. vol 229. issue 2. 2012-07-17. PMID:22266927. |
in the hippocampus of 20 weeks old, but not 10 weeks old, cntf -/- mice, these changes correlated with a loss of parvalbumin immunoreactive gabaergic interneurons and a reduction of serotonin levels as well as 5-ht receptor 1a expression. |
2012-07-17 |
2023-08-12 |
mouse |
| Blanca Erika Gutiérrez-Guzmán, J Jesús Hernández-Pérez, Miguel Ángel López-Vázquez, Cesar Soria Fregozo, Miguel Ángel Guevara, María Esther Olvera-Corté. Serotonin depletion of supramammillary/posterior hypothalamus nuclei produces place learning deficiencies and alters the concomitant hippocampal theta activity in rats. European journal of pharmacology. vol 682. issue 1-3. 2012-07-17. PMID:22387092. |
serotonin depletion of supramammillary/posterior hypothalamus nuclei produces place learning deficiencies and alters the concomitant hippocampal theta activity in rats. |
2012-07-17 |
2023-08-12 |
rat |
| Blanca Erika Gutiérrez-Guzmán, J Jesús Hernández-Pérez, Miguel Ángel López-Vázquez, Cesar Soria Fregozo, Miguel Ángel Guevara, María Esther Olvera-Corté. Serotonin depletion of supramammillary/posterior hypothalamus nuclei produces place learning deficiencies and alters the concomitant hippocampal theta activity in rats. European journal of pharmacology. vol 682. issue 1-3. 2012-07-17. PMID:22387092. |
the participation of the sumn in place learning and modulation of hippocampal theta activity were recently shown; thus, we questioned whether serotonin acting on sumn/phn could modulate place learning ability and concurrent hippocampal theta activity. |
2012-07-17 |
2023-08-12 |
rat |