| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Oomagar. [Effects of morphine and diazepam pretreatment on immobilization stress-induced increase of serotonin metabolism in discrete brain areas of the rat]. Fukuoka igaku zasshi = Hukuoka acta medica. vol 80. issue 2. 1989-08-25. PMID:2753446. |
acute immobilization induced increases in 5hiaa content in prefrontal cortex polar field (fcp), prefrontal cortex medial field (fcm), n. preopticus medialis (pm), area hypothalamicus lateralis (l) and n. dorsomedialis (dm) and also increases in 5ht content in the pm, l, dm, and n. arcuatus median eminence (arc-me). |
1989-08-25 |
2023-08-11 |
rat |
| S R Sesack, B S Bunne. Pharmacological characterization of the receptor mediating electrophysiological responses to dopamine in the rat medial prefrontal cortex: a microiontophoretic study. The Journal of pharmacology and experimental therapeutics. vol 248. issue 3. 1989-05-12. PMID:2564893. |
the d2 selective antagonist, sulpiride, specifically attenuated da-induced inhibition of deep layer pfc neurons, without blocking the inhibitory effects of gamma-aminobutyric acid (gaba) or serotonin (5-ht). |
1989-05-12 |
2023-08-11 |
rat |
| A Kalsbeek, J P de Bruin, M A Matthijssen, H B Uyling. Ontogeny of open field activity in rats after neonatal lesioning of the mesocortical dopaminergic projection. Behavioural brain research. vol 32. issue 2. 1989-05-04. PMID:2923656. |
medial vta lesions caused a moderate dopamine depletion in the prefrontal cortex and an almost complete cortical serotonin depletion, and resulted in transient hyperactivity in the open field at postnatal day 25. |
1989-05-04 |
2023-08-11 |
rat |
| A Kalsbeek, J P De Bruin, M G Feenstra, M A Matthijssen, H B Uyling. Neonatal thermal lesions of the mesolimbocortical dopaminergic projection decrease food-hoarding behavior. Brain research. vol 475. issue 1. 1989-02-28. PMID:3214729. |
biochemical analysis demonstrated an approximately 50% depletion of both dopamine and serotonin in the prefrontal cortex of males, whereas noradrenaline levels were unchanged. |
1989-02-28 |
2023-08-11 |
rat |
| K Herrick-Davis, M Titeler, S Leonhardt, R Struble, D Pric. Serotonin 5-HT1D receptors in human prefrontal cortex and caudate: interaction with a GTP binding protein. Journal of neurochemistry. vol 51. issue 6. 1988-12-20. PMID:3141589. |
serotonin 5-ht1d receptors in human prefrontal cortex and caudate: interaction with a gtp binding protein. |
1988-12-20 |
2023-08-11 |
human |
| K Herrick-Davis, M Titeler, S Leonhardt, R Struble, D Pric. Serotonin 5-HT1D receptors in human prefrontal cortex and caudate: interaction with a GTP binding protein. Journal of neurochemistry. vol 51. issue 6. 1988-12-20. PMID:3141589. |
radioligand binding studies were performed to characterize serotonin 5-ht1d receptors in postmortem human prefrontal cortex and caudate homogenates. |
1988-12-20 |
2023-08-11 |
human |
| K Herrick-Davis, M Titeler, S Leonhardt, R Struble, D Pric. Serotonin 5-HT1D receptors in human prefrontal cortex and caudate: interaction with a GTP binding protein. Journal of neurochemistry. vol 51. issue 6. 1988-12-20. PMID:3141589. |
these findings are supportive of the presence of serotonin 5-ht1d receptors in human prefrontal cortex and caudate which appear to be coupled to a gtp binding protein. |
1988-12-20 |
2023-08-11 |
human |
| A J Dunn, N R Hal. Thymic extracts and lymphokine-containing supernatant fluids stimulate the pituitary-adrenal axis, but not cerebral catecholamine or indoleamine metabolism. Brain, behavior, and immunity. vol 1. issue 2. 1988-08-08. PMID:3452441. |
injection of thymosin fraction 5 (tf5) or the supernatant fluid from concanavalin a-stimulated rat spleen cells into mice significantly increased plasma concentrations of corticosterone at 1 or 3 h. however, measurement of the concentrations of the catecholamines, norepinephrine and dopamine, the indoleamine, serotonin, and their major metabolites, in prefrontal cortex, parietal cortex, nucleus accumbens, septum, caudate-putamen, hypothalamus, and brain stem did not indicate any statistically significant changes. |
1988-08-08 |
2023-08-11 |
mouse |
| A J Dun. Changes in plasma and brain tryptophan and brain serotonin and 5-hydroxyindoleacetic acid after footshock stress. Life sciences. vol 42. issue 19. 1988-06-20. PMID:2452945. |
footshock treatment significantly decreased the content of 5-ht in prefrontal cortex and hypothalamus, but not brainstem at 15 min, but the decreases were reversed by 30 min. |
1988-06-20 |
2023-08-11 |
Not clear |
| A J Dun. Changes in plasma and brain tryptophan and brain serotonin and 5-hydroxyindoleacetic acid after footshock stress. Life sciences. vol 42. issue 19. 1988-06-20. PMID:2452945. |
5-hiaa, the major catabolite of 5-ht, increased in prefrontal cortex after 15 min, and in prefrontal cortex and hypothalamus after 30 min footshock. |
1988-06-20 |
2023-08-11 |
Not clear |
| A Cudennec, D Duverger, T Nishikawa, A McRae-Degueurce, E T MacKenzie, B Scatto. Influence of ascending serotonergic pathways on glucose use in the conscious rat brain. I. Effects of electrolytic or neurotoxic lesions of the dorsal and/or median raphé nucleus. Brain research. vol 444. issue 2. 1988-06-02. PMID:3359293. |
the efficacy of both electrolytic and neurotoxic lesions was verified, in each animal, by neurochemical microassay of 5-hydroxytryptamine and its metabolite in samples of striatum, hippocampus and prefrontal cortex. |
1988-06-02 |
2023-08-11 |
rat |
| D J Mokler, K W Stoudt, L C Sherman, R H Rec. The effects of intracranial administration of hallucinogens on operant behavior in the rat. II. 2,5-Dimethoxy-4-methylamphetamine (DOM). Pharmacology, biochemistry, and behavior. vol 28. issue 3. 1988-01-11. PMID:3685066. |
sites were chosen as major areas of the brain 5-hydroxytryptamine (5-ht) system: the dorsal and median raphe nuclei, dorsal hippocampus, lateral habenular nuclei and the prefrontal cortex. |
1988-01-11 |
2023-08-11 |
rat |
| M Boranić, D Pericić, M Poljak-Blazi, V Sverko, T Marott. Suppression of immune response in rats by stress and drugs interfering with metabolism of serotonin. Annals of the New York Academy of Sciences. vol 496. 1987-07-29. PMID:2440371. |
treatment with pcpa also suppressed the pfc response, but this suppression was accompanied by decreased levels of brain serotonin and of 5-hiaa. |
1987-07-29 |
2023-08-11 |
rat |
| E Fride, M Weinstoc. Increased interhemispheric coupling of the dopamine systems induced by prenatal stress. Brain research bulletin. vol 18. issue 3. 1987-07-16. PMID:2438016. |
dopamine and serotonin turnover rates were measured in the left and right prefrontal cortex, nucleus accumbens and caudate nucleus of adult rats which were stressed prenatally. |
1987-07-16 |
2023-08-11 |
rat |
| K Yamaguchi, T Nabeshima, T Kameyam. Role of dopaminergic and serotonergic neuronal systems in the prefrontal cortex of rats in phencyclidine-induced behaviors. Journal of pharmacobio-dynamics. vol 9. issue 12. 1987-06-01. PMID:3572718. |
pretreatment with p-chlorophenylalanine (300 mg/kg), a serotonin (5-ht) synthesis inhibitor, attenuated head-weaving induced by injection of pcp into the prefrontal cortex. |
1987-06-01 |
2023-08-11 |
rat |
| T Kuroki, T Matsumoto, M Hirano, H Kagoshima, H Yao, H Uchimura, K Nakamura, T Nakahar. Long-lasting effect of systemically administrated caerulein on monoaminergic neuronal pathways in rat brain. Neuropeptides. vol 9. issue 2. 1987-05-27. PMID:2437491. |
significantly elevated 5-hydroxyindoleacetic acid (5hiaa) levels in the prefrontal cortex lateral field, nucleus accumbens, tuberculum olfactorium and striatum after 2 hours, together with a significant increase in striatal serotonin (5ht). |
1987-05-27 |
2023-08-11 |
rat |
| M R Palmer, O Tottmar, R A Deitric. Electrophysiological effects of monoamine-derived aldehydes on single neurons in neocortex and cerebellum in rats. Alcoholism, clinical and experimental research. vol 10. issue 6. 1987-03-18. PMID:2433956. |
serotonin and 5-hydroxy-3-acetaldehyde caused pronounced depression of firing rates both of cerebellar purkinje neurons and neurons in prefrontal cortex. |
1987-03-18 |
2023-08-11 |
rat |
| T Mita, S Hanada, N Nishino, T Kuno, H Nakai, T Yamadori, Y Mizoi, C Tanak. Decreased serotonin S2 and increased dopamine D2 receptors in chronic schizophrenics. Biological psychiatry. vol 21. issue 14. 1987-02-13. PMID:2947636. |
serotonin s2 and dopamine d2 receptors in the prefrontal cortex and caudate nucleus of postmortem brains of chronic schizophrenics were studied using 3h-ketanserin and 3h-spiperone, respectively. |
1987-02-13 |
2023-08-11 |
Not clear |
| D J Mokler, K W Stoudt, L C Sherman, R H Rec. The effects of intracranial administration of hallucinogens on operant behavior in the rat. I. Lysergic acid diethylamide. Pharmacology, biochemistry, and behavior. vol 25. issue 4. 1987-01-13. PMID:3538062. |
the sites were chosen as major areas of the brain 5-hydroxytryptamine (5ht) system: the dorsal and median raphe nuclei, dorsal hippocampus, lateral habenular nuclei, and the prefrontal cortex. |
1987-01-13 |
2023-08-11 |
rat |
| O Wolkowitz, M Sutton, M Koulu, R Labarca, L Wilkinson, A Doran, R Hauger, D Pickar, J Crawle. Chronic corticosterone administration in rats: behavioral and biochemical evidence of increased central dopaminergic activity. European journal of pharmacology. vol 122. issue 3. 1986-07-03. PMID:3709658. |
a subgroup of steroid-treated rats which was more behaviorally responsive to corticosterone also showed increased caudate 5-hydroxyindole acetic acid and decreased prefrontal cortex dopamine and serotonin. |
1986-07-03 |
2023-08-11 |
rat |