| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J P Rivot, D Pointis, J M Besso. A comparison of the effects of morphine on 5-HT metabolism in the periaqueductal gray, ventromedial medulla and medullary dorsal horn: in vivo electrochemical studies in freely moving rats. Brain research. vol 495. issue 1. 1989-10-19. PMID:2776031. |
these results are compared with our previous studies using the same methodological approaches and show that morphine caused a significant and specific increase in 5-ht metabolism at the levels of nucleus raphe magnus (nrm) and medullary dorsal horn. |
1989-10-19 |
2023-08-11 |
rat |
| S G Khasabov, Z A Tamarov. [Effect of serotonin on the background activity of neurons in the isolated spinal cord semisegment of the rat]. Neirofiziologiia = Neurophysiology. vol 21. issue 3. 1989-09-25. PMID:2770915. |
50% investigated neurons in dorsal horn and 70.6% interneurons in the ventral horn reacted on 5-ht. |
1989-09-25 |
2023-08-11 |
rat |
| S G Khasabov, Z A Tamarov. [Effect of serotonin on the background activity of neurons in the isolated spinal cord semisegment of the rat]. Neirofiziologiia = Neurophysiology. vol 21. issue 3. 1989-09-25. PMID:2770915. |
in the dorsal horn 5-ht evoked activation in 62.4% of responding interneurons, depression--in 8.4% and mixed reaction--in 29.2%. |
1989-09-25 |
2023-08-11 |
rat |
| T Tashiro, M A Ruda, T Satoda, R Matsushima, N Mizun. Convergence of serotonin-, enkephalin- and substance P-like immunoreactive afferent fibers onto cat medullary dorsal horn projection neurons: a triple immunocytochemical staining technique combined with the retrograde HRP-tracing method. Brain research. vol 491. issue 2. 1989-09-22. PMID:2475211. |
convergence of serotonin (5-ht)-, enkephalin (enk)-, and substance p (sp)-like immunoreactive (li) afferent fibers onto cat medullary dorsal horn projection neurons was examined by retrogradely labeling trigeminothalamic neurons and immunocytochemically labeling 5-ht, enk and sp fibers in the same tissue section using distinct chromogens. |
1989-09-22 |
2023-08-11 |
cat |
| I Kitayama, A Cintra, A M Janson, K Fuxe, L F Agnati, P Eneroth, M Aronsson, A Härfstrand, H W Steinbush, T J Visse. Chronic immobilization stress: evidence for decreases of 5-hydroxy-tryptamine immunoreactivity and for increases of glucocorticoid receptor immunoreactivity in various brain regions of the male rat. Journal of neural transmission. vol 77. issue 2-3. 1989-09-11. PMID:2760606. |
5-ht ir in nerve terminals was only affected in the dorsal horn, where 5-ht ir was increased in the substantia gelatinosa. |
1989-09-11 |
2023-08-11 |
rat |
| H Bras, P Cavallari, E Jankowska, D McCre. Comparison of effects of monoamines on transmission in spinal pathways from group I and II muscle afferents in the cat. Experimental brain research. vol 76. issue 1. 1989-08-31. PMID:2753107. |
of field potentials recorded at various locations, both na and 5-ht depressed those evoked from group ii fibres in the intermediate and ventral horn regions of the spinal cord but not, or only occasionally, in the dorsal horn. |
1989-08-31 |
2023-08-11 |
cat |
| F D Rodríguez, R E Rodrígue. Intrathecal administration of 5,6-DHT or 5,7-DHT reduces morphine and substance P-antinociceptive activity in the rat. Neuropeptides. vol 13. issue 2. 1989-08-10. PMID:2472573. |
our results confirm the existence of a relationship between the 5ht and sp descending systems, which control the nociceptive information at the level of the dorsal horn of the spinal cord. |
1989-08-10 |
2023-08-11 |
rat |
| B W Newton, R W Hamil. Target regulation of the serotonin and substance P innervation of the sexually dimorphic cremaster nucleus. Brain research. vol 485. issue 1. 1989-06-23. PMID:2470469. |
day-of-birth castration reduces the adult cn sp innervation pattern to a greater degree than the 5-ht pattern and this may be attributed to a substantial loss of primary afferent information to the dorsal horn of the spinal cord. |
1989-06-23 |
2023-08-11 |
rat |
| J P Rivot, D Pointis, J M Besso. In vivo electrochemical detection of 5-hydroxyindole within the trigeminal nucleus caudalis of freely moving rats: the effect of morphine. Brain research. vol 463. issue 2. 1989-01-26. PMID:3196919. |
it is concluded that in non-anesthetized freely moving animals morphine clearly increases the metabolism of serotonin (5-ht) in the medullary dorsal horn. |
1989-01-26 |
2023-08-11 |
rat |
| R Magoul, A Oblin, A Calas, S Araned. Serotonergic projections to the spinal cord but not those to the olfactory bulb also contain substance P. A combined immunocytochemical and autoradiographic study following retrograde axonal transport of [3H]serotonin labeled products. Neuroscience. vol 26. issue 3. 1989-01-17. PMID:2462186. |
they represent about 48% of the serotonin radiolabeled neurons projecting to the thoracic spinal cord, where a great number of varicosities were observed immunolabeled, radiolabeled and doubly immuno-radiolabeled in the dorsal horn. |
1989-01-17 |
2023-08-11 |
rat |
| K C Fone, P Dix, D R Tomlinson, G W Bennett, C A Marsde. Spinal effects of chronic intrathecal administration of the thyrotrophin-releasing hormone analogue (CG 3509) in rats. Brain research. vol 455. issue 1. 1988-10-14. PMID:2458166. |
repeated cg 3509 administration selectively elevated chat activity and the level of 5-hydroxytryptamine (5-ht) in the ventral but not in the dorsal horn of the spinal cord, while 5-hydroxyindoleacetic acid (5-hiaa) and trh levels were unaltered in either region. |
1988-10-14 |
2023-08-11 |
rat |
| N el-Yassir, S M Fleetwood-Walker, R Mitchel. Heterogeneous effects of serotonin in the dorsal horn of rat: the involvement of 5-HT1 receptor subtypes. Brain research. vol 456. issue 1. 1988-10-13. PMID:2970278. |
heterogeneous effects of serotonin in the dorsal horn of rat: the involvement of 5-ht1 receptor subtypes. |
1988-10-13 |
2023-08-11 |
rat |
| N el-Yassir, S M Fleetwood-Walker, R Mitchel. Heterogeneous effects of serotonin in the dorsal horn of rat: the involvement of 5-HT1 receptor subtypes. Brain research. vol 456. issue 1. 1988-10-13. PMID:2970278. |
the effect of ionophoretically applied serotonin (5-ht) was tested on cutaneous sensory responses of multireceptive dorsal horn neurones in the anaesthetized rat. |
1988-10-13 |
2023-08-11 |
rat |
| J C Pearson, L Jenne. Localization of serotonin- and substance P-like immunofluorescence in the caudal spinal trigeminal nucleus of the rat. Neuroscience letters. vol 88. issue 2. 1988-07-22. PMID:2454433. |
the results of the present study suggest that fibers containing coexistent 5-ht and sp may be involved in the processing of nociceptive somatic sensation in the medullary dorsal horn of rat. |
1988-07-22 |
2023-08-11 |
rat |
| L S Sorkin, J L Steinman, M G Hughes, W D Willis, D J McAdo. Microdialysis recovery of serotonin released in spinal cord dorsal horn. Journal of neuroscience methods. vol 23. issue 2. 1988-05-13. PMID:2451773. |
microdialysis recovery of serotonin released in spinal cord dorsal horn. |
1988-05-13 |
2023-08-11 |
Not clear |
| S Khanna, J G Sinclai. Fluoxetine and pargyline on the nucleus raphe magnus inhibition of cat multireceptive dorsal horn neurones. General pharmacology. vol 19. issue 2. 1988-05-12. PMID:3258264. |
to determine whether serotonin (5-ht) is involved in the nucleus raphe magnus (nrm) inhibition of cat multireceptive dorsal horn neurones, the nrm inhibition was tested with drugs (fluoxetine and pargyline) that should enhance 5-ht synaptic activity. |
1988-05-12 |
2023-08-11 |
cat |
| L X Zhu, C Y Li, C F J. Dual action of substance P in nociception and pain modulation at spinal level. Scientia Sinica. Series B, Chemical, biological, agricultural, medical & earth sciences. vol 30. issue 7. 1988-04-28. PMID:2451286. |
in view of the fact that the inhibitory effect of stimulation of nucleus raphe magnus (nrm) on the nociceptive response of dorsal horn neurons in rats depleted of 5-ht with parachlorophenylalanine (pcpa) can be significantly blocked by iontophoretic sp-antagonist, it is supposed that sp may be involved in descending modulation on spinal pain transmission. |
1988-04-28 |
2023-08-11 |
rat |
| G Daval, D Vergé, A I Basbaum, S Bourgoin, M Hamo. Autoradiographic evidence of serotonin1 binding sites on primary afferent fibres in the dorsal horn of the rat spinal cord. Neuroscience letters. vol 83. issue 1-2. 1988-04-12. PMID:3441302. |
both treatments produced a significant loss of 5-ht (-20 to -30%) and opiate (-30 to -45%) binding sites within the superficial layers of the dorsal horn, suggesting they are partly located presynaptically on primary afferent fibres. |
1988-04-12 |
2023-08-11 |
rat |
| S M Carlton, J L Steinman, G R Hillman, W D Willi. Differential effects of p-chlorophenylalanine on indoleamines in brainstem nuclei and spinal cord of rats. II. Identification of immunohistochemically stained structures using computer-assisted image enhancement techniques. Brain research. vol 426. issue 2. 1988-02-20. PMID:2961412. |
furthermore, a computer program designed to isolate terminal structures in the spinal cord identified a differential depletion of 5-ht terminals in the dorsal horn versus the ventral horn. |
1988-02-20 |
2023-08-11 |
rat |
| J P Rivot, B Calvino, J M Besso. Is there a serotonergic tonic descending inhibition on the responses of dorsal horn convergent neurons to C-fibre inputs? Brain research. vol 403. issue 1. 1987-05-20. PMID:3828806. |
in the anaesthetized rat the intravenous injection of 5-ht antagonists, cinanserin and methysergide, induces in two-thirds of neurones studied, an increase in the responsiveness of dorsal horn convergent neurones to c-fibre stimulation. |
1987-05-20 |
2023-08-11 |
rat |