| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D H Harkness, M S Brownfiel. A thyrotropin-releasing hormone-containing system in the rat dorsal horn separate from serotonin. Brain research. vol 384. issue 2. 1987-01-05. PMID:3096489. |
a thyrotropin-releasing hormone-containing system in the rat dorsal horn separate from serotonin. |
1987-01-05 |
2023-08-11 |
rat |
| D H Harkness, M S Brownfiel. A thyrotropin-releasing hormone-containing system in the rat dorsal horn separate from serotonin. Brain research. vol 384. issue 2. 1987-01-05. PMID:3096489. |
trh immunoreactivity in the dorsal horn and iml was resistant to the effects of the selective serotonin neurotoxin, 5,7-dht, while the ventral horn was depleted of trh staining. |
1987-01-05 |
2023-08-11 |
rat |
| D H Harkness, M S Brownfiel. A thyrotropin-releasing hormone-containing system in the rat dorsal horn separate from serotonin. Brain research. vol 384. issue 2. 1987-01-05. PMID:3096489. |
these findings provide evidence that a trh-containing system exists in the dorsal horn of the rat and that it is distinct from the descending medullary raphe system that contains 5-ht; suggest that a population of trh-containing fibers that project to the iml may not contain 5-ht; and confirm previously published results that 5-ht and trh coexist in terminals in the ventral horn of the spinal cord. |
1987-01-05 |
2023-08-11 |
rat |
| T Tsubaki, T Tanaka, A Shigemats. [Endogenous inhibitory system in pain]. Journal of UOEH. vol 8. issue 2. 1986-09-29. PMID:3529278. |
the mechanism of pag stimulation analgesia is partly due to an activation of serotonin containing neurons which descend from nrm to the spinal dorsal horn and activated by pag stimulation. |
1986-09-29 |
2023-08-11 |
Not clear |
| S Jeftinija, C Raspantini, M Randić, T L Yaksh, V L Go, A A Larso. Altered responsiveness to substance P and 5-hydroxytryptamine in cat dorsal horn neurons after 5-HT depletion with p-chlorophenylalanine. Brain research. vol 368. issue 1. 1986-05-22. PMID:2420413. |
altered responsiveness to substance p and 5-hydroxytryptamine in cat dorsal horn neurons after 5-ht depletion with p-chlorophenylalanine. |
1986-05-22 |
2023-08-11 |
cat |
| S Jeftinija, C Raspantini, M Randić, T L Yaksh, V L Go, A A Larso. Altered responsiveness to substance P and 5-hydroxytryptamine in cat dorsal horn neurons after 5-HT depletion with p-chlorophenylalanine. Brain research. vol 368. issue 1. 1986-05-22. PMID:2420413. |
the responsiveness of functionally identified cat spinal dorsal horn neurons to iontophoretically applied substance p (sp) and 5-hydroxytryptamine (5-ht) has been investigated by means of extracellular recording after 5-ht depletion with p-chlorophenylalanine (p-cpa). |
1986-05-22 |
2023-08-11 |
cat |
| S Jeftinija, C Raspantini, M Randić, T L Yaksh, V L Go, A A Larso. Altered responsiveness to substance P and 5-hydroxytryptamine in cat dorsal horn neurons after 5-HT depletion with p-chlorophenylalanine. Brain research. vol 368. issue 1. 1986-05-22. PMID:2420413. |
in the present study we have demonstrated an altered responsiveness of dorsal horn neurons to locally applied sp and 5-ht. |
1986-05-22 |
2023-08-11 |
cat |
| S Jeftinija, C Raspantini, M Randić, T L Yaksh, V L Go, A A Larso. Altered responsiveness to substance P and 5-hydroxytryptamine in cat dorsal horn neurons after 5-HT depletion with p-chlorophenylalanine. Brain research. vol 368. issue 1. 1986-05-22. PMID:2420413. |
at the same time, depression induced by 5-ht in the dorsal horn cells was virtually absent in p-cpa-pretreated animals. |
1986-05-22 |
2023-08-11 |
cat |
| S Jeftinija, C Raspantini, M Randić, T L Yaksh, V L Go, A A Larso. Altered responsiveness to substance P and 5-hydroxytryptamine in cat dorsal horn neurons after 5-HT depletion with p-chlorophenylalanine. Brain research. vol 368. issue 1. 1986-05-22. PMID:2420413. |
the present study has shown that pharmacological depletion of 5-ht has two major effects: (1) it increases significantly the proportion of dorsal horn neurons excited by sp and 5-ht; and (2) it is ineffective in inducing 5-ht supersensitivity. |
1986-05-22 |
2023-08-11 |
cat |
| M Fitzgerald, M Koltzenbur. The functional development of descending inhibitory pathways in the dorsolateral funiculus of the newborn rat spinal cord. Brain research. vol 389. issue 1-2. 1986-04-07. PMID:3948011. |
it is suggested that this is due to delayed maturation of crucial interneurones in the dorsal horn or to insufficient levels of 5-hydroxytryptamine or other neurochemicals in the descending dlf axon terminals. |
1986-04-07 |
2023-08-11 |
rat |
| M H Robert. 5-Hydroxytryptamine and antinociception. Neuropharmacology. vol 23. issue 12B. 1985-04-17. PMID:6098854. |
the postulate that an antinociceptive system of neurones projects from periaqueductal gray (pag) to nucleus raphe magnus (nrm) and then to the dorsal horn, via cells containing 5-ht, has proved difficult to support experimentally. |
1985-04-17 |
2023-08-12 |
Not clear |
| M H Robert. 5-Hydroxytryptamine and antinociception. Neuropharmacology. vol 23. issue 12B. 1985-04-17. PMID:6098854. |
5-hydroxytryptamine, applied iontophoretically to dorsal horn neurones, does reduce the nociceptive responses of these neurones but it is not clear that activity in 5-ht cells of the raphe-spinal system is responsible for the descending inhibition of nociception. |
1985-04-17 |
2023-08-12 |
Not clear |
| M H Robert. 5-Hydroxytryptamine and antinociception. Neuropharmacology. vol 23. issue 12B. 1985-04-17. PMID:6098854. |
although antagonists of 5-ht block some of the antinociceptive effects of both stimulation of the periaqueductal gray and systemically-applied morphine, they do not block the centrifugal inhibition of dorsal horn cells or the effects of iontophoretically applied 5-ht. |
1985-04-17 |
2023-08-12 |
Not clear |
| R H Ho, A L LaValle. 5-Hydroxytryptamine in the spinal cord of the domestic fowl. Brain research bulletin. vol 13. issue 3. 1985-01-03. PMID:6388737. |
the apparent intimate relationship between dorsal horn cells and numerous 5ht structures may render them good models to study the possible role of 5ht in the modulation of nociception in the dorsal horn. |
1985-01-03 |
2023-08-12 |
Not clear |
| V Miletic, M J Hoffert, M A Ruda, R Dubner, Y Shigenag. Serotoninergic axonal contacts on identified cat spinal dorsal horn neurons and their correlation with nucleus raphe magnus stimulation. The Journal of comparative neurology. vol 228. issue 1. 1984-11-09. PMID:6384280. |
these data reveal a differential distribution of 5-ht contacts on neurons in spinal laminae i and ii, and indicate that at least a portion of the nrm modulation of dorsal horn neuronal activity is serotoninergic and concentrated on the dendritic shafts of nociceptive lamina i neurons and lamina ii stalked cells. |
1984-11-09 |
2023-08-12 |
cat |
| A J Todd, J Milla. Antagonism of 5-hydroxytryptamine-evoked excitation in the superficial dorsal horn of the cat spinal cord by methysergide. Neuroscience letters. vol 48. issue 2. 1984-11-09. PMID:6483279. |
ionophoretically applied methysergide was tested on 9 units excited by 5-hydroxytryptamine (5-ht) recorded in the superficial dorsal horn of cat spinal cord. |
1984-11-09 |
2023-08-12 |
cat |
| E J Glazer, J Ramachandran, A I Basbau. Radioimmunocytochemistry using a tritiated goat anti-rabbit second antibody. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 32. issue 7. 1984-08-02. PMID:6203962. |
affinity-purified goat anti-rabbit immunoglobulin g (gar) was conjugated with (3h)-propionyl succinimidate and used to localize substance p (sp), enkephalin (enk), and serotonin immunoreactive sites in the spinal dorsal horn and medulla of the rat and cat. |
1984-08-02 |
2023-08-12 |
rat |
| E J Glazer, A I Basbau. Axons which take up [3H]serotonin are presynaptic to enkephalin immunoreactive neurons in cat dorsal horn. Brain research. vol 298. issue 2. 1984-07-13. PMID:6202371. |
axons which take up [3h]serotonin are presynaptic to enkephalin immunoreactive neurons in cat dorsal horn. |
1984-07-13 |
2023-08-12 |
cat |
| E J Glazer, A I Basbau. Axons which take up [3H]serotonin are presynaptic to enkephalin immunoreactive neurons in cat dorsal horn. Brain research. vol 298. issue 2. 1984-07-13. PMID:6202371. |
through combined ultrastructural localization of enk immunoreactivity and [3h]5-ht uptake sites, it was found that 5-ht radiolabeled axons contact enk immunoreactive cell bodies and small dendrites in the cat superficial dorsal horn. |
1984-07-13 |
2023-08-12 |
cat |
| P Savard, L M Blanchard, Y Mérand, P Bédard, J H Dussault, A Dupon. Influences of both thyroid and bovine growth hormones on substance P, thyrotropin-releasing hormone, serotonin and 5-hydroxyindoleacetic acid contents in the lumbar spinal cord of developing rats. Brain research. vol 315. issue 1. 1984-07-09. PMID:6202374. |
we demonstrated that: (1) neonatal hyperthyroidism decreased substance p and trh levels in the dorsal and ventral horns respectively, without modifying serotonin and 5-hiaa contents; (2) neonatal hypothyroidism increased the concentration of substance p in dorsal horn, of trh in ventral horn (confirming our previous work), of serotonin in ventral horn, and of 5-hiaa in both ventral and dorsal horns; (3) t4-replacement therapy abolishes hypothyroid effects on substance p, trh, and 5-hiaa, but not on 5-ht accumulation; and (4) bovine growth hormone-replacement therapy has no therapeutic action on the hypothyroid-induced accumulation of substance p, trh, serotonin and 5-hiaa. |
1984-07-09 |
2023-08-12 |
rat |