| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhijun He, Huajie Zhang, Xiaoqian Li, Liming Shen, Nan Li, Shuiyuan Cheng, Qiong Li. Comparative proteomic analysis of cerebral cortex revealed neuroprotective mechanism of esculentoside A on Alzheimer's disease. European journal of pharmacology. 2023-12-21. PMID:38128868. |
comparative proteomic analysis of cerebral cortex revealed neuroprotective mechanism of esculentoside a on alzheimer's disease. |
2023-12-21 |
2023-12-24 |
mouse |
| Rami Lee, Han Sang Lee, Won-Woo Kim, Manho Kim, Seung-Yeol Na. Cognitive function improvement effects of gintonin-enriched fraction in subjective memory impairment: An assessor- and participant-blinded placebo-controlled study. Journal of ginseng research. vol 47. issue 6. 2023-12-19. PMID:38107399. |
the gintonin-enriched fraction (gef) inhibits amyloid plaque accumulation in the cortex and hippocampus, improves cognitive dysfunction by increasing acetylcholine levels, and promoted hippocampal neurogenesis in an animal model of alzheimer's disease. |
2023-12-19 |
2023-12-21 |
human |
| Joseph Giorgio, Jenna N Adams, Anne Maass, William J Jagust, Michael Breakspea. Amyloid induced hyperexcitability in default mode network drives medial temporal hyperactivity and early tau accumulation. Neuron. 2023-12-14. PMID:38096815. |
in early alzheimer's disease (ad) β-amyloid (aβ) deposits throughout association cortex and tau appears in the entorhinal cortex (ec). |
2023-12-14 |
2023-12-17 |
Not clear |
| Xin Shen, Zhixiang Cui, Yidan Wei, Yingnan Huo, Duo Yu, Xin Zhang, Shirui Ma. Exploring the potential to enhance drug distribution in the brain subregion via intranasal delivery of nanoemulsion in combination with borneol as a guider. Asian journal of pharmaceutical sciences. vol 18. issue 6. 2023-12-13. PMID:38089837. |
the number of people with alzheimer's disease (ad) is increasing annually, with the nidus mainly concentrated in the cortex and hippocampus. |
2023-12-13 |
2023-12-17 |
Not clear |
| Marios G Krokidis, Aristidis G Vrahatis, Konstantinos Lazaros, Konstantina Skolariki, Themis P Exarchos, Panagiotis Vlamo. Machine Learning Analysis of Alzheimer's Disease Single-Cell RNA-Sequencing Data across Cortex and Hippocampus Regions. Current issues in molecular biology. vol 45. issue 11. 2023-11-25. PMID:37998721. |
machine learning analysis of alzheimer's disease single-cell rna-sequencing data across cortex and hippocampus regions. |
2023-11-25 |
2023-11-28 |
mouse |
| Marios G Krokidis, Aristidis G Vrahatis, Konstantinos Lazaros, Konstantina Skolariki, Themis P Exarchos, Panagiotis Vlamo. Machine Learning Analysis of Alzheimer's Disease Single-Cell RNA-Sequencing Data across Cortex and Hippocampus Regions. Current issues in molecular biology. vol 45. issue 11. 2023-11-25. PMID:37998721. |
our methodology utilizes single-cell rna sequencing data from healthy and alzheimer's disease (ad) samples, focused on the cortex and hippocampus regions in mice. |
2023-11-25 |
2023-11-28 |
mouse |
| Matthew Rowan, Annie Goettemoeller, Emmie Banks, Katharine McCann, Prateek Kumar, Kelly South, Viktor Olah, Christina Ramelow, Duc Duong, Nicholas Seyfried, Srikant Rangaraju, David Weinshenke. Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. Research square. 2023-11-21. PMID:37987015. |
in mouse models, early hyperexcitability has been shown in the entorhinal cortex, the first cortical region impacted by alzheimer's disease2-4. |
2023-11-21 |
2023-11-29 |
mouse |
| Jessica R Gaunt, Norliyana Zainolabidin, Alaric K K Yip, Jia Min Tan, Aloysius Y T Low, Albert I Chen, Toh Hean Ch'n. Cytokine enrichment in deep cerebellar nuclei is contributed by multiple glial populations and linked to reduced amyloid plaque pathology. Journal of neuroinflammation. vol 20. issue 1. 2023-11-18. PMID:37978387. |
alzheimer's disease (ad) pathology and amyloid-beta (aβ) plaque deposition progress slowly in the cerebellum compared to other brain regions, while the entorhinal cortex (ec) is one of the most vulnerable regions. |
2023-11-18 |
2023-11-20 |
mouse |
| Zhigao Wang, Xiaoxu Wang, Yingxu Ma, Peixu Cong, Xincen Wang, Yu Song, Jie Xu, Changhu Xu. Astaxanthin alleviates ganglioside metabolism disorder in the cortex of Alzheimer's disease mice. Food & function. 2023-11-06. PMID:37929718. |
astaxanthin alleviates ganglioside metabolism disorder in the cortex of alzheimer's disease mice. |
2023-11-06 |
2023-11-08 |
mouse |
| Marthe Mieling, Martin Göttlich, Mushfa Yousuf, Nico Bunzec. Basal forebrain activity predicts functional degeneration in the entorhinal cortex in Alzheimer's disease. Brain communications. vol 5. issue 5. 2023-10-30. PMID:37901036. |
basal forebrain activity predicts functional degeneration in the entorhinal cortex in alzheimer's disease. |
2023-10-30 |
2023-11-08 |
Not clear |
| Marthe Mieling, Martin Göttlich, Mushfa Yousuf, Nico Bunzec. Basal forebrain activity predicts functional degeneration in the entorhinal cortex in Alzheimer's disease. Brain communications. vol 5. issue 5. 2023-10-30. PMID:37901036. |
recent models of alzheimer's disease suggest the nucleus basalis of meynert (nbm) as an early origin of structural degeneration followed by the entorhinal cortex (ec). |
2023-10-30 |
2023-11-08 |
Not clear |
| Dibyadeep Datta, Isabella Perone, Yury M Morozov, Jon Arellano, Alvaro Duque, Pasko Rakic, Christopher H van Dyck, Amy F T Arnste. Localization of PDE4D, HCN1 channels, and mGluR3 in rhesus macaque entorhinal cortex may confer vulnerability in Alzheimer's disease. Cerebral cortex (New York, N.Y. : 1991). 2023-10-24. PMID:37874022. |
localization of pde4d, hcn1 channels, and mglur3 in rhesus macaque entorhinal cortex may confer vulnerability in alzheimer's disease. |
2023-10-24 |
2023-11-08 |
monkey |
| Dibyadeep Datta, Isabella Perone, Yury M Morozov, Jon Arellano, Alvaro Duque, Pasko Rakic, Christopher H van Dyck, Amy F T Arnste. Localization of PDE4D, HCN1 channels, and mGluR3 in rhesus macaque entorhinal cortex may confer vulnerability in Alzheimer's disease. Cerebral cortex (New York, N.Y. : 1991). 2023-10-24. PMID:37874022. |
alzheimer's disease cortical tau pathology initiates in the layer ii cell clusters of entorhinal cortex, but it is not known why these specific neurons are so vulnerable. |
2023-10-24 |
2023-11-08 |
monkey |
| Kayo Yukawa, Satomi Yamamoto-Mcguire, Louis Cafaro, Christine Hong, Fredrik Kamme, Tsuneya Ikezu, Seiko Ikez. Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice. Acta neuropathologica communications. vol 11. issue 1. 2023-10-20. PMID:37853497. |
tau tubulin kinase-1 (ttbk1), a neuron-specific tau kinase, is highly expressed in the entorhinal cortex and hippocampal regions, where early tau pathology evolves in alzheimer's disease (ad). |
2023-10-20 |
2023-11-08 |
mouse |
| Yan Zhang, Yu-Shen Yang, Cong-Mei Wang, Wei-Can Chen, Xin-Li Chen, Fan Wu, He-Fan H. Copper metabolism-related Genes in entorhinal cortex for Alzheimer's disease. Scientific reports. vol 13. issue 1. 2023-10-14. PMID:37838728. |
copper metabolism-related genes in entorhinal cortex for alzheimer's disease. |
2023-10-14 |
2023-11-08 |
Not clear |
| Huimin Chen, Jiajia Cai, Aozhe Wang, Wantang Su, Chunyan Ji, Li Zha. Treadmill exercise prevents the hyperexcitability of pyramidal neurons in medial entorhinal cortex in the 3xTg-AD mouse model of Alzheimer's disease. Experimental gerontology. 2023-10-13. PMID:37832802. |
treadmill exercise prevents the hyperexcitability of pyramidal neurons in medial entorhinal cortex in the 3xtg-ad mouse model of alzheimer's disease. |
2023-10-13 |
2023-10-15 |
mouse |
| Vahid Gazestani, Tushar Kamath, Naeem M Nadaf, Antonios Dougalis, S J Burris, Brendan Rooney, Antti Junkkari, Charles Vanderburg, Anssi Pelkonen, Mireia Gomez-Budia, Nelli-Noora Välimäki, Tuomas Rauramaa, Martine Therrien, Anne M Koivisto, Matthew Tegtmeyer, Sanna-Kaisa Herukka, Abdulraouf Abdulraouf, Samuel E Marsh, Mikko Hiltunen, Ralda Nehme, Tarja Malm, Beth Stevens, Ville Leinonen, Evan Z Macosk. Early Alzheimer's disease pathology in human cortex involves transient cell states. Cell. vol 186. issue 20. 2023-09-29. PMID:37774681. |
early alzheimer's disease pathology in human cortex involves transient cell states. |
2023-09-29 |
2023-10-07 |
human |
| Meixiang Huang, Carolyn Tallon, Xiaolei Zhu, Kaitlyn D J Huizar, Silvia Picciolini, Ajit G Thomas, Lukas Tenora, Wathsala Liyanage, Francesca Rodà, Alice Gualerzi, Rangaramanujam M Kannan, Marzia Bedoni, Rana Rais, Barbara S Slushe. Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice. Pharmaceutics. vol 15. issue 9. 2023-09-28. PMID:37765332. |
the progression of alzheimer's disease (ad) correlates with the propagation of hyperphosphorylated tau (ptau) from the entorhinal cortex to the hippocampus and neocortex. |
2023-09-28 |
2023-10-07 |
mouse |
| Anna Papazoglou, Christina Henseler, Sandra Weickhardt, Johanna Daubner, Teresa Schiffer, Karl Broich, Jürgen Hescheler, Dan Ehninger, Catharina Scholl, Britta Haenisch, Agapios Sachinidis, Marco Weiergräbe. Whole genome transcriptome data from the WT cortex and hippocampus of female and male control and APP/PS1 Alzheimer's disease mice. Data in brief. vol 50. 2023-09-28. PMID:37767130. |
whole genome transcriptome data from the wt cortex and hippocampus of female and male control and app/ps1 alzheimer's disease mice. |
2023-09-28 |
2023-10-07 |
mouse |
| Jia Wang, Fang Zhou, Chang-E Xiong, Gui-Ping Wang, Lin-Wanyue Chen, Yu-Tong Zhang, Shi-Ge Qi, Zhi-Hui Wang, Can Mei, Yu-Jia Xu, Jian-Bo Zhan, Jing Chen. Serum sirtuin1: a potential blood biomarker for early diagnosis of Alzheimer's disease. Aging. vol 15. 2023-09-24. PMID:37742223. |
sirtuin 1, a nicotinamide adenine dinucleotide-dependent deacetylase that is highly expressed in the hippocampus and anterior cortex tissues related to alzheimer's disease pathology, can cross the blood-brain barrier and is a promising biomarker. |
2023-09-24 |
2023-10-07 |
Not clear |