| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael Anekson Widjaya, Chia-Hsin Liu, Shin-Da Lee, Wei-Chung Chen. Transcriptomics Meta-Analysis Reveals Phagosome and Innate Immune System Dysfunction as Potential Mechanisms in the Cortex of Alzheimer's Disease Mouse Strains. Journal of molecular neuroscience : MN. 2023-09-21. PMID:37733230. |
transcriptomics meta-analysis reveals phagosome and innate immune system dysfunction as potential mechanisms in the cortex of alzheimer's disease mouse strains. |
2023-09-21 |
2023-10-07 |
mouse |
| Marthe Mieling, Hannah Meier, Nico Bunzec. Structural Degeneration of the Nucleus basalis of Meynert in Mild Cognitive Impairment and Alzheimer's Disease - Evidence from an MRI-based Meta-Analysis. Neuroscience and biobehavioral reviews. 2023-09-17. PMID:37717861. |
recent models of alzheimer's disease (ad) suggest that neuropathological changes of the medial temporal lobe, especially entorhinal cortex, are preceded by degenerations of the cholinergic nucleus basalis of meynert (nbm). |
2023-09-17 |
2023-10-07 |
human |
| Lingxuan Chen, Zoé Christenson Wick, Lauren M Vetere, Nick Vaughan, Albert Jurkowski, Angelina Galas, Keziah S Diego, Paul Philipsberg, Ivan Soler, Yu Feng, Denise J Cai, Tristan Shuma. Progressive excitability changes in the medial entorhinal cortex in the 3xTg mouse model of Alzheimer's disease pathology. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-09-15. PMID:37714705. |
progressive excitability changes in the medial entorhinal cortex in the 3xtg mouse model of alzheimer's disease pathology. |
2023-09-15 |
2023-10-07 |
mouse |
| Jan Oltmer, Douglas N Greve, Stefano Cerri, Natalya Slepneva, Josue Llamas-Rodríguez, Juan Eugenio Iglesias, Koen Van Leemput, Samantha N Champion, Matthew P Frosch, Jean C Augustinac. Assessing individual variability of the entorhinal subfields in health and disease. The Journal of comparative neurology. 2023-09-13. PMID:37700618. |
the entorhinal cortex (ec) is essential for memory and affected early in the progression of alzheimer's disease (ad). |
2023-09-13 |
2023-10-07 |
Not clear |
| Natallia Makarava, Olga Mychko, Kara Molesworth, Jennifer Chen-Yu Chang, Rebecca J Henry, Natalya Tsymbalyuk, Volodymyr Gerzanich, J Marc Simard, David J Loane, Ilia V Baskako. Region-Specific Homeostatic Identity of Astrocytes Is Essential for Defining Their Response to Pathological Insults. Cells. vol 12. issue 17. 2023-09-08. PMID:37681904. |
to address this question, region-specific gene expression profiling was performed for four brain regions (cortex, hippocampus, thalamus, and hypothalamus) in mice using a custom nanostring panel consisting of selected sets of genes associated with astrocyte functions and their reactivity for five conditions: prion disease, traumatic brain injury, brain ischemia, 5xfad alzheimer's disease model and normal aging. |
2023-09-08 |
2023-10-07 |
mouse |
| Germán Plascencia-Villa, George Perr. Roles of Oxidative Stress in Synaptic Dysfunction and Neuronal Cell Death in Alzheimer's Disease. Antioxidants (Basel, Switzerland). vol 12. issue 8. 2023-08-26. PMID:37627623. |
alzheimer's disease (ad) is a brain disorder that progressively undermines memory and thinking skills by affecting the hippocampus and entorhinal cortex. |
2023-08-26 |
2023-09-07 |
Not clear |
| Wensheng Guo, Xin Mao, Ding Han, Hongqi Wang, Wanning Zhang, Guitao Zhang, Ning Zhang, Binbin Nie, Hui Li, Yizhi Song, Yan Wu, Lirong Chan. Sleep deprivation aggravated amyloid β oligomers-induced damage to the cerebellum of rats: Evidence from magnetic resonance imaging. Aging brain. vol 4. 2023-08-21. PMID:37600754. |
for quite a long time, researches on alzheimer's disease (ad) primarily focused on the cortex and hippocampus, while the cerebellum has been ignored because of its abnormalities considered to appear in the late stage of ad. |
2023-08-21 |
2023-09-07 |
rat |
| Maria Olmedillas, Bianca Brawek, Kaizhen Li, Cris Richter, Olga Garaschu. Plaque vicinity as a hotspot of microglial turnover in a mouse model of Alzheimer's disease. Glia. 2023-08-19. PMID:37596829. |
by using microrna-9 regulated viral vectors for multicolor labeling and longitudinal in vivo monitoring of individual microglia, we followed their fate in the cortex of healthy adult mice and at the onset of amyloidosis in a mouse model of alzheimer's disease. |
2023-08-19 |
2023-10-07 |
mouse |
| Emma F Garland, Oliver Dennett, Laurie C Lau, David S Chatelet, Michel Bottlaender, James A R Nicoll, Delphine Boch. The mitochondrial protein TSPO in Alzheimer's disease: relation to the severity of AD pathology and the neuroinflammatory environment. Journal of neuroinflammation. vol 20. issue 1. 2023-08-14. PMID:37580767. |
in alzheimer's disease (ad), the cerebellum is the pseudo-reference region for comparison with the cerebral cortex due to the absence of ad pathology and lower levels of tspo. |
2023-08-14 |
2023-09-07 |
human |
| Yingteng Zhang, Feibiao Zha. Diffusion tensor imaging (DTI) Analysis Based on Tract-based spatial statistics (TBSS) and Classification Using Multi-Metric in Alzheimer's Disease. Journal of integrative neuroscience. vol 22. issue 4. 2023-07-31. PMID:37519167. |
alzheimer's disease (ad) is a brain disorder characterized by atrophy of cerebral cortex and neurofibrillary tangles. |
2023-07-31 |
2023-08-14 |
Not clear |
| Mubeen A Ansari, Aishah Al-Jarallah, Fawzi A Babike. Impaired Insulin Signaling Alters Mediators of Hippocampal Synaptic Dynamics/Plasticity: A Possible Mechanism of Hyperglycemia-Induced Cognitive Impairment. Cells. vol 12. issue 13. 2023-07-14. PMID:37443762. |
alzheimer's disease (ad) is a neurological condition that affects the elderly and is characterized by progressive and irreversible neurodegeneration in the cerebral cortex [...]. |
2023-07-14 |
2023-08-14 |
Not clear |
| Leysan Vasileva, Gulnara Gaynanova, Farida Valeeva, Grigory Belyaev, Irina Zueva, Kseniya Bushmeleva, Guzel Sibgatullina, Dmitry Samigullin, Alexandra Vyshtakalyuk, Konstantin Petrov, Lucia Zakharova, Oleg Sinyashi. Mitochondria-Targeted Delivery Strategy of Dual-Loaded Liposomes for Alzheimer's Disease Therapy. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37445673. |
experiments on transgenic mice with an alzheimer's disease model (app/ps1) demonstrated that the intranasal administration of liposomes within 21 days resulted in enhanced learning abilities and a reduction in the formation rate of aβ plaques in the entorhinal cortex and hippocampus of the brain. |
2023-07-14 |
2023-08-14 |
mouse |
| Shu Matsushita, Hiroyuki Tatekawa, Daiju Ueda, Hirotaka Takita, Daisuke Horiuchi, Taro Tsukamoto, Taro Shimono, Yukio Mik. The Association of Metabolic Brain MRI, Amyloid PET, and Clinical Factors: A Study of Alzheimer's Disease and Normal Controls From the Open Access Series of Imaging Studies Dataset. Journal of magnetic resonance imaging : JMRI. 2023-07-10. PMID:37424114. |
although brain activities in alzheimer's disease (ad) might be evaluated mri and pet, the relationships between brain temperature (bt), the index of diffusivity along the perivascular space (alps index), and amyloid deposition in the cerebral cortex are still unclear. |
2023-07-10 |
2023-08-14 |
Not clear |
| Samira A Maboudian, Ethan H Willbrand, William J Jagust, Kevin S Weine. Defining overlooked structures reveals new associations between cortex and cognition in aging and Alzheimer's disease. bioRxiv : the preprint server for biology. 2023-07-10. PMID:37425904. |
defining overlooked structures reveals new associations between cortex and cognition in aging and alzheimer's disease. |
2023-07-10 |
2023-08-14 |
human |
| Samira A Maboudian, Ethan H Willbrand, William J Jagust, Kevin S Weine. Defining overlooked structures reveals new associations between cortex and cognition in aging and Alzheimer's disease. bioRxiv : the preprint server for biology. 2023-07-10. PMID:37425904. |
recent work suggests that indentations of the cerebral cortex, or sulci, may be uniquely vulnerable to atrophy in aging and alzheimer's disease (ad) and that posteromedial cortex (pmc) is particularly vulnerable to atrophy and pathology accumulation. |
2023-07-10 |
2023-08-14 |
human |
| Angelo Arleo, Martin Bareš, Jessica A Bernard, Hannah R Bogoian, Muriel M K Bruchhage, Patrick Bryant, Erik S Carlson, Chetwyn C H Chan, Liang-Kung Chen, Chih-Ping Chung, Vonetta M Dotson, Pavel Filip, Xavier Guell, Christophe Habas, Heidi I L Jacobs, Shinji Kakei, Tatia M C Lee, Maria Leggio, Maria Misiura, Hiroshi Mitoma, Giusy Olivito, Stephen Ramanoël, Zeynab Rezaee, Colby L Samstag, Jeremy D Schmahmann, Kaoru Sekiyama, Clive H Y Wong, Masatoshi Yamashita, Mario Mant. Consensus Paper: Cerebellum and Ageing. Cerebellum (London, England). 2023-07-10. PMID:37428408. |
neuroimaging studies highlight that the cerebellum might be involved in the cognitive decline occurring in alzheimer's disease (ad), independently of contributions of the cerebral cortex. |
2023-07-10 |
2023-08-14 |
human |
| Lingxuan Chen, Zoé Christenson Wick, Lauren M Vetere, Nick Vaughan, Albert Jurkowski, Angelina Galas, Keziah S Diego, Paul Philipsberg, Denise J Cai, Tristan Shuma. Progressive excitability changes in the medial entorhinal cortex in the 3xTg mouse model of Alzheimer's disease pathology. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37398359. |
progressive excitability changes in the medial entorhinal cortex in the 3xtg mouse model of alzheimer's disease pathology. |
2023-07-03 |
2023-08-14 |
mouse |
| Vahid Gazestani, Tushar Kamath, Naeem M Nadaf, S J Burris, Brendan Rooney, Antti Junkkari, Charles Vanderburg, Tuomas Rauramaa, Martine Therrien, Matthew Tegtmeyer, Sanna-Kaisa Herukka, Abdulraouf Abdulraouf, Samuel Marsh, Tarja Malm, Mikko Hiltunen, Ralda Nehme, Beth Stevens, Ville Leinonen, Evan Z Macosk. Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states. bioRxiv : the preprint server for biology. 2023-06-19. PMID:37333365. |
early alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states. |
2023-06-19 |
2023-08-14 |
human |
| Anika Wuestefeld, Hannah Baumeister, Jenna N Adams, Robin de Flores, Carl Hodgetts, Negar Mazloum-Farzaghi, Rosanna K Olsen, Vyash Puliyadi, Tammy T Tran, Arnold Bakker, Kelsey L Canada, Marshall A Dalton, Ana M Daugherty, Renaud La Joie, Lei Wang, Madigan Bedard, Esther Buendia, Amanda Denning, David J Irwin, Ranjit Ittyerah, Edward B Lee, Sydney Lim, Maria Mercedes Iñiguez de Onzoño Martin, Monica Munoz Lopez, Theresa Schuck, Winifred Trotman, Alicia Vela, Paul Yushkevich, Katrin Amunts, Jean C Augustinack, Song-Lin Ding, Ricardo Insausti, Olga Kedo, David Berron, Laura E M Wiss. Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories. bioRxiv : the preprint server for biology. 2023-06-09. PMID:37292729. |
the medial temporal lobe (mtl) cortex, located adjacent to the hippocampus, is crucial for memory and prone to the accumulation of certain neuropathologies such as alzheimer's disease neurofibrillary tau tangles. |
2023-06-09 |
2023-08-14 |
human |
| Chiara Falcicchia, Francesca Tozzi, Martina Gabrielli, Stefano Amoretti, Greta Masini, Gabriele Nardi, Stefano Guglielmo, Gian Michele Ratto, Ottavio Arancio, Claudia Verderio, Nicola Origli. Microglial extracellular vesicles induce Alzheimer's disease-related cortico-hippocampal network dysfunction. Brain communications. vol 5. issue 3. 2023-06-08. PMID:37288314. |
here, using chronic eeg recordings, we show that a single injection of extracellular vesicles carrying β-amyloid into the mouse entorhinal cortex could trigger alterations in the cortical and hippocampal activity that are reminiscent of those found in alzheimer's disease mouse models and human patients. |
2023-06-08 |
2023-08-14 |
mouse |