| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kun Tu, Wenhui Zhou, Shubing Kon. Integrating Multi-omics Data for Alzheimer's Disease to Explore Its Biomarkers Via the Hypergraph-Regularized Joint Deep Semi-Non-Negative Matrix Factorization Algorithm. Journal of molecular neuroscience : MN. vol 74. issue 2. 2024-04-15. PMID:38619646. |
integrating multi-omics data for alzheimer's disease to explore its biomarkers via the hypergraph-regularized joint deep semi-non-negative matrix factorization algorithm. |
2024-04-15 |
2024-04-17 |
Not clear |
| Lan Shui, Dean Shibata, Kwun Chuen Gary Chan, Wenbo Zhang, Junhyoun Sung, David R Hayno. Longitudinal Relationship Between Brain Atrophy Patterns, Cognitive Decline, and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease Explored by Orthonormal Projective Non-Negative Matrix Factorization. Journal of Alzheimer's disease : JAD. 2024-03-22. PMID:38517788. |
longitudinal relationship between brain atrophy patterns, cognitive decline, and cerebrospinal fluid biomarkers in alzheimer's disease explored by orthonormal projective non-negative matrix factorization. |
2024-03-22 |
2024-03-25 |
Not clear |
| Qi Guo, Lingyan Ping, Eric B Dammer, Luming Yin, Kaiming Xu, Anantharaman Shantaraman, Edward J Fox, Todd E Golde, Erik C B Johnson, Blaine R Roberts, James J Lah, Allan I Levey, Nicholas T Seyfrie. Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease. Research square. 2024-03-18. PMID:38464223. |
heparin binding proteins (hbps) with roles in extracellular matrix assembly are strongly correlated to β-amyloid (aβ) and tau pathology in alzheimer's disease (ad) brain and cerebrospinal fluid (csf). |
2024-03-18 |
2024-03-20 |
Not clear |
| Arastu Sharma, Collin Y Ewal. Clearance of extracellular human amyloid-β aggregates in microPublication biology. vol 2024. 2024-01-30. PMID:38287930. |
however, in alzheimer's disease patients, amyloid-β (aβ) plaques are found embedded in the extracellular matrix and surrounded by collagens, which might hinder these antibodies from targeting the plaques. |
2024-01-30 |
2024-02-01 |
human |
| Klaudia Głowacz, Marcin Drozd, Weronika Tokarska, Nina E Wezynfeld, Patrycja Ciosek-Skibińsk. Quantum dots-based "chemical tongue" for the discrimination of short-length Aβ peptides. Mikrochimica acta. vol 191. issue 2. 2024-01-15. PMID:38224352. |
a "chemical tongue" is proposed based on thiomalic acid-capped quantum dots (qds) with signal enrichment provided by excitation-emission matrix (eem) fluorescence spectroscopy for the determination of close structural analogs-short-length amyloid β (aβ) peptides related to alzheimer's disease. |
2024-01-15 |
2024-01-17 |
Not clear |
| Matthew Amontree, Matthew Nelson, Lara Stefansson, Daniel Pak, Kathleen Maguire-Zeiss, R Scott Turner, Katherine Conan. Resveratrol differentially affects MMP-9 release from neurons and glia; implications for therapeutic efficacy. Journal of neurochemistry. 2024-01-01. PMID:38163875. |
resveratrol, a naturally occurring polyphenol that activates sirtuin 1 (sirt1), has been shown to reduce overall levels of matrix metalloprotease-9 (mmp-9) in cerebrospinal fluid (csf) samples from patients with alzheimer's dementia (ad). |
2024-01-01 |
2024-01-05 |
Not clear |
| Shamila Firdaus, Susanne Boye, Andreas Janke, Peter Friedel, Anna Janaszewska, Dietmar Appelhans, Martin Müller, Barbara Klajnert-Maculewicz, Brigitte Voit, Albena Ledere. Advancing Antiamyloidogenic Activity by Fine-Tuning Macromolecular Topology. Biomacromolecules. 2023-11-08. PMID:37939018. |
amyloid β peptide can aggregate into thin β-sheet fibrils or plaques deposited on the extracellular matrix, which is the hallmark of alzheimer's disease. |
2023-11-08 |
2023-11-20 |
Not clear |
| Yi-Jiao He, Jin-Sheng Liu, Lei Zhang, Jin-Wu Ya. A quinolinium-based dual-functional NIR fluorescent probe for the imaging of Aβ aggregation and mitochondrial pH. Talanta. vol 268. issue Pt 1. 2023-11-02. PMID:37918242. |
among them, aβ peptide, one of the targets of alzheimer's disease, is closely related to mitochondrial autophagy, during the process of mitochondrial autophagy, the mitochondrial matrix will undergo acidification and the ph will be obviously reduced. |
2023-11-02 |
2023-11-08 |
Not clear |
| Saurabh Sihag, Gonzalo Mateos, Corey T McMillan, Alejandro Ribeir. Explainable Brain Age Prediction using coVariance Neural Networks. ArXiv. 2023-10-09. PMID:37808092. |
specifically, our brain age prediction framework extends beyond the coarse metric of brain age gap in alzheimer's disease (ad) and we make two important observations: (i) vnns can assign anatomical interpretability to elevated brain age gap in ad by identifying contributing brain regions, (ii) the interpretability offered by vnns is contingent on their ability to exploit specific eigenvectors of the anatomical covariance matrix. |
2023-10-09 |
2023-10-15 |
Not clear |
| Nallupillai Paramakrishnan, Khian Giap Lim, Yamunna Paramaswaran, Nemat Ali, Mohammad Waseem, Gamal A Shazly, Yousef A Bin Jardan, Arunachalam Muthurama. Astaxanthin: A Marine Drug That Ameliorates Cerebrovascular-Damage-Associated Alzheimer's Disease in a Zebrafish Model via the Inhibition of Matrix Metalloprotease-13. Marine drugs. vol 21. issue 8. 2023-08-25. PMID:37623714. |
astaxanthin: a marine drug that ameliorates cerebrovascular-damage-associated alzheimer's disease in a zebrafish model via the inhibition of matrix metalloprotease-13. |
2023-08-25 |
2023-09-07 |
zebrafish |
| Zhengrong Zhang, Kaiwen Yu, Yang You, Peizhou Jiang, Zhiping Wu, Michael A DeTure, Dennis W Dickson, Seiko Ikezu, Junmin Peng, Tsuneya Ikez. Comprehensive characterization of human brain-derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications. Journal of extracellular vesicles. vol 12. issue 8. 2023-08-11. PMID:37563857. |
in contrast, mage samples were more enriched in molecules related to lipoproteins, cell-substrate junction and microglia, whereas sec samples were highly enriched in molecules related to extracellular matrix, alzheimer's disease and astrocytes. |
2023-08-11 |
2023-08-16 |
human |
| Mari Aksnes, Elettra Capogna, Didac Vidal-Piñeiro, Farrukh Abbas Chaudhry, Marius Myrstad, Ane-Victoria Idland, Nathalie Bodd Halaas, Shams Dakhil, Kaj Blennow, Henrik Zetterberg, Kristine Beate Walhovd, Leiv Otto Watne, Anders Martin Fjel. Matrix metalloproteinases are associated with brain atrophy in cognitively unimpaired individuals. Neurobiology of aging. vol 131. 2023-08-07. PMID:37549446. |
matrix metalloproteinases (mmps) and their tissue inhibitors (timps) have been linked to age-related neurodegeneration and alzheimer's disease (ad), but their role in normal aging is poorly understood. |
2023-08-07 |
2023-08-14 |
Not clear |
| Irina Georgieva, Jana Tchekalarova, Dimitar Iliev, Rumiana Tzonev. Endothelial Senescence and Its Impact on Angiogenesis in Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 14. 2023-07-29. PMID:37511104. |
this narrative review highlights the complex interplay between senescence, oxidative stress, extracellular vesicles, and the extracellular matrix and emphasizes the crucial role of angiogenesis in aging and alzheimer's disease. |
2023-07-29 |
2023-08-14 |
Not clear |
| Jiahang Sha, Jingxuan Bao, Kefei Liu, Shu Yang, Zixuan Wen, Junhao Wen, Yuhan Cui, Boning Tong, Jason H Moore, Andrew J Saykin, Christos Davatzikos, Qi Long, Li She. Preference Matrix Guided Sparse Canonical Correlation Analysis for Mining Brain Imaging Genetic Associations in Alzheimer's Disease. Methods (San Diego, Calif.). 2023-07-28. PMID:37507059. |
preference matrix guided sparse canonical correlation analysis for mining brain imaging genetic associations in alzheimer's disease. |
2023-07-28 |
2023-08-14 |
Not clear |
| Wei Kong, Feifan Xu, Shuaiqun Wang, Kai Wei, Gen Wen, Yaling Y. Application of orthogonal sparse joint non-negative matrix factorization based on connectivity in Alzheimer's disease research. Mathematical biosciences and engineering : MBE. vol 20. issue 6. 2023-06-16. PMID:37322917. |
application of orthogonal sparse joint non-negative matrix factorization based on connectivity in alzheimer's disease research. |
2023-06-16 |
2023-08-14 |
Not clear |
| Matthew Amontree, Samantha Deasy, R Scott Turner, Katherine Conan. Matrix disequilibrium in Alzheimer's disease and conditions that increase Alzheimer's disease risk. Frontiers in neuroscience. vol 17. 2023-06-12. PMID:37304012. |
matrix disequilibrium in alzheimer's disease and conditions that increase alzheimer's disease risk. |
2023-06-12 |
2023-08-14 |
Not clear |
| Mari Aksnes, Trine H Edwin, Ingvild Saltvedt, Rannveig S Eldholm, Farrukh A Chaudhry, Nathalie B Halaas, Marius Myrstad, Leiv O Watne, Anne-Brita Knapsko. Sex-specific associations of matrix metalloproteinases in Alzheimer's disease. Biology of sex differences. vol 14. issue 1. 2023-05-24. PMID:37221606. |
sex-specific associations of matrix metalloproteinases in alzheimer's disease. |
2023-05-24 |
2023-08-14 |
Not clear |
| Ahmed Khalid, Ebrahim Mohammed Senan, Khalil Al-Wagih, Mamoun Mohammad Ali Al-Azzam, Ziad Mohammad Alkhraish. Automatic Analysis of MRI Images for Early Prediction of Alzheimer's Disease Stages Based on Hybrid Features of CNN and Handcrafted Features. Diagnostics (Basel, Switzerland). vol 13. issue 9. 2023-05-14. PMID:37175045. |
because of the similarities in the characteristics of the early stages of alzheimer's, this study aimed to extract the features in several methods and integrate the features extracted from more than one method into the same features matrix. |
2023-05-14 |
2023-08-14 |
Not clear |
| Mikel L Olson, Bretton Badenoch, Megan Blatti, Christine Buching, Nic Gleww. Muscarinic Cholinergic Receptor Antagonism Impairs Spatial Memory Retrieval and Minimizes Retrieval-Induced Alterations in Matrix Metalloproteinase-9. Behavioural brain research. 2023-04-29. PMID:37119978. |
one such disorder, alzheimer's disease (ad) is associated with the abnormal expression of various proteins including matrix metalloproteinase-9 (mmp-9), an enzyme known to regulate hippocampus-dependent memory. |
2023-04-29 |
2023-08-14 |
rat |
| Hongmin Cai, Huan Liu, Defu Yang, Guorong Wu, Bin Hu, Jiazhou Che. Estimating Outlier-Immunized Common Harmonic Waves for Brain Network Analyses on the Stiefel Manifold. IEEE journal of biomedical and health informatics. vol PP. 2023-04-07. PMID:37028067. |
since brain network organization is essentially governed by the harmonic waves derived from the eigen-system of the underlying laplacian matrix, discovering the harmonic-based alterations provides a new window to understand the pathogenic mechanism of alzheimer's disease (ad) in a unified reference space. |
2023-04-07 |
2023-08-14 |
Not clear |