| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Perry, P Richey, S L Siedlak, P Galloway, M Kawai, P Cra. Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases. Brain research. vol 579. issue 2. 1992-08-18. PMID:1628222. |
the extracellular matrix protein heparin sulfate proteoglycans (hspg) has been found in the neurofibrillary pathology of alzheimer disease. |
1992-08-18 |
2023-08-11 |
Not clear |
| J R Backstrom, C A Miller, Z A Töké. Characterization of neutral proteinases from Alzheimer-affected and control brain specimens: identification of calcium-dependent metalloproteinases from the hippocampus. Journal of neurochemistry. vol 58. issue 3. 1992-03-13. PMID:1738004. |
the results demonstrate an elevated level of metalloproteinase activities, capable of degrading tissue matrix components, in the hippocampus from postmortem alzheimer patients. |
1992-03-13 |
2023-08-11 |
human |
| G Carmeliet, G David, J J Cassima. Cellular ageing of Alzheimer's disease and Down syndrome cells in culture. Mutation research. vol 256. issue 2-6. 1992-02-06. PMID:1722012. |
we therefore investigated several parameters of adhesion in the skin fibroblast cultures: adhesion to a fibronectin coat, adhesion to extracellular matrix of alzheimer's disease cultures and semi-quantification of adhesion-related molecules (beta 1-integrin, cell surface proteoglycans, extracellular matrix proteoglycans, extracellular matrix fibronectin). |
1992-02-06 |
2023-08-11 |
Not clear |
| S Narindrasorasak, D Lowery, P Gonzalez-DeWhitt, R A Poorman, B Greenberg, R Kisilevsk. High affinity interactions between the Alzheimer's beta-amyloid precursor proteins and the basement membrane form of heparan sulfate proteoglycan. The Journal of biological chemistry. vol 266. issue 20. 1991-08-19. PMID:1906461. |
our results suggest that specific interactions between the aap proteins and the extracellular matrix may be involved in the nucleation stages of alzheimer's disease type amyloidogenesis. |
1991-08-19 |
2023-08-11 |
Not clear |
| J P Brandel, E C Hirsch, S Malessa, C Duyckaerts, P Cervera, Y Agi. Differential vulnerability of cholinergic projections to the mediodorsal nucleus of the thalamus in senile dementia of Alzheimer type and progressive supranuclear palsy. Neuroscience. vol 41. issue 1. 1991-07-29. PMID:2057062. |
differential loss of innervation to the matrix and patches in progressive supranuclear palsy and senile dementia of alzheimer type may in turn differentially affect mediodorsal nucleus innervation of the frontal cortex, resulting in dissimilar symptomatologies. |
1991-07-29 |
2023-08-11 |
human |
| J P Brandel, E C Hirsch, S Malessa, C Duyckaerts, P Cervera, Y Agi. Differential vulnerability of cholinergic projections to the mediodorsal nucleus of the thalamus in senile dementia of Alzheimer type and progressive supranuclear palsy. Neuroscience. vol 41. issue 1. 1991-07-29. PMID:2057062. |
in patients with senile dementia of alzheimer type, choline acetyltransferase-positive varicosities decreased by 34% in the matrix, but 46% in the patches. |
1991-07-29 |
2023-08-11 |
human |
| F G Klier, G Cole, W Stallcup, D Schuber. Amyloid beta-protein precursor is associated with extracellular matrix. Brain research. vol 515. issue 1-2. 1990-08-01. PMID:2113416. |
the possible role of matrix associated abpp in the pathogenesis of alzheimer's disease is discussed. |
1990-08-01 |
2023-08-11 |
Not clear |
| E P Bendit. What role(s) may extracellular matrix, particularly heparan sulfate, play in amyloid of Alzheimer's disease. Neurobiology of aging. vol 10. issue 5. 1989-12-18. PMID:2530463. |
what role(s) may extracellular matrix, particularly heparan sulfate, play in amyloid of alzheimer's disease. |
1989-12-18 |
2023-08-11 |
Not clear |
| T Arendt, V Bigl, A Tennstedt, A Arend. Correlation between cortical plaque count and neuronal loss in the nucleus basalis in Alzheimer's disease. Neuroscience letters. vol 48. issue 1. 1984-10-15. PMID:6472737. |
in order to substantiate the hypothesis of a cholinergic matrix for neuritic plaque formation in alzheimer's disease (ad), the relationship between the loss of cholinergic neurons in the basal forebrain and formation of neuritic plaques in the cerebral cortex was studied in 5 cases of neuropathologically verified ad. |
1984-10-15 |
2023-08-12 |
Not clear |