Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Trevor Humby, Jessica B Eddy, Mark A Good, Amy C Reichelt, Lawrence S Wilkinso. A novel translational assay of response inhibition and impulsivity: effects of prefrontal cortex lesions, drugs used in ADHD, and serotonin 2C receptor antagonism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 11. 2014-05-05. PMID:23657439. |
a novel translational assay of response inhibition and impulsivity: effects of prefrontal cortex lesions, drugs used in adhd, and serotonin 2c receptor antagonism. |
2014-05-05 |
2023-08-12 |
mouse |
Satoshi Tsujimoto, Akira Yasumura, Yushiro Yamashita, Miyuki Torii, Makiko Kaga, Masumi Inagak. Increased prefrontal oxygenation related to distractor-resistant working memory in children with attention-deficit/hyperactivity disorder (ADHD). Child psychiatry and human development. vol 44. issue 5. 2014-05-02. PMID:23385518. |
to this end, we studied hemodynamic activity in the prefrontal cortex using near-infrared spectroscopy while 16 children with adhd and 10 typically developing (td) children performed a working memory task. |
2014-05-02 |
2023-08-12 |
Not clear |
Michael H Ston. A new look at borderline personality disorder and related disorders: hyper-reactivity in the limbic system and lower centers. Psychodynamic psychiatry. vol 41. issue 3. 2014-04-23. PMID:24001165. |
if one shifts the spotlight to neurophysiology, as captured by mri studies, however, it emerges that an important subtype of bpd, and also bd, adhd, and ied-share common features of abnormalities and peculiarities in the limbic system and in the cortex, especially the prefrontal cortex. |
2014-04-23 |
2023-08-12 |
Not clear |
Masato Umehara, Yukio Ago, Kazumi Fujita, Naoki Hiramatsu, Kazuhiro Takuma, Toshio Matsud. Effects of serotonin-norepinephrine reuptake inhibitors on locomotion and prefrontal monoamine release in spontaneously hypertensive rats. European journal of pharmacology. vol 702. issue 1-3. 2014-02-04. PMID:23376565. |
catecholamine neurotransmission in the prefrontal cortex plays a key role in the therapeutic actions of drugs for attention-deficit/hyperactivity disorder (adhd). |
2014-02-04 |
2023-08-12 |
rat |
Masato Umehara, Yukio Ago, Kazumi Fujita, Naoki Hiramatsu, Kazuhiro Takuma, Toshio Matsud. Effects of serotonin-norepinephrine reuptake inhibitors on locomotion and prefrontal monoamine release in spontaneously hypertensive rats. European journal of pharmacology. vol 702. issue 1-3. 2014-02-04. PMID:23376565. |
in this study, we examined the effects of acute treatment with serotonin-norepinephrine reuptake inhibitors on locomotion and the extracellular levels of monoamines in the prefrontal cortex in spontaneously hypertensive rats (shr), an animal model of adhd. |
2014-02-04 |
2023-08-12 |
rat |
Rebecca M Hakvoort Schwerdtfeger, Nadia Alahyane, Donald C Brien, Brian C Coe, Patrick W Stroman, Douglas P Muno. Preparatory neural networks are impaired in adults with attention-deficit/hyperactivity disorder during the antisaccade task. NeuroImage. Clinical. vol 2. 2013-11-01. PMID:24179760. |
interestingly, unlike controls, adults with adhd produced greater activation than controls in dorsolateral prefrontal cortex during antisaccade execution, perhaps as part of compensatory mechanisms to optimize antisaccade production. |
2013-11-01 |
2023-08-12 |
human |
Ziarih Hawi, Natasha Matthews, Joseph Wagner, Robyn H Wallace, Tim J Butler, Alasdair Vance, Lindsey Kent, Michael Gill, Mark A Bellgrov. DNA variation in the SNAP25 gene confers risk to ADHD and is associated with reduced expression in prefrontal cortex. PloS one. vol 8. issue 4. 2013-10-22. PMID:23593184. |
dna variation in the snap25 gene confers risk to adhd and is associated with reduced expression in prefrontal cortex. |
2013-10-22 |
2023-08-12 |
mouse |
Sucharita S Somkuwar, Mahesh Darna, Kathleen M Kantak, Linda P Dwoski. Adolescence methylphenidate treatment in a rodent model of attention deficit/hyperactivity disorder: dopamine transporter function and cellular distribution in adulthood. Biochemical pharmacology. vol 86. issue 2. 2013-09-03. PMID:23623751. |
attention deficit/hyperactivity disorder (adhd) is attributed to dysfunction of the prefrontal cortex. |
2013-09-03 |
2023-08-12 |
rat |
Sucharita S Somkuwar, Mahesh Darna, Kathleen M Kantak, Linda P Dwoski. Adolescence methylphenidate treatment in a rodent model of attention deficit/hyperactivity disorder: dopamine transporter function and cellular distribution in adulthood. Biochemical pharmacology. vol 86. issue 2. 2013-09-03. PMID:23623751. |
importantly, prefrontal cortex subregions, orbitofrontal cortex (ofc) and medial prefrontal cortex (mpfc), have been shown to have distinct roles in adhd and cocaine self-administration. |
2013-09-03 |
2023-08-12 |
rat |
Sharwin Tafazoli, Joseph O'Neill, Anthony Bejjani, Ronald Ly, Noriko Salamon, James T McCracken, Jeffry R Alger, Jennifer G Levit. 1H MRSI of middle frontal gyrus in pediatric ADHD. Journal of psychiatric research. vol 47. issue 4. 2013-08-21. PMID:23273650. |
neuroimaging studies in multiple modalities have implicated the left or right dorsolateral prefrontal cortex (here, middle frontal gyrus) in attentional functions, in adhd, and in dopamine agonist treatment of adhd. |
2013-08-21 |
2023-08-12 |
Not clear |
Taciana G Costa Dias, Vanessa B Wilson, Deepti R Bathula, Swathi P Iyer, Kathryn L Mills, Bria L Thurlow, Corinne A Stevens, Erica D Musser, Samuel D Carpenter, David S Grayson, Suzanne H Mitchell, Joel T Nigg, Damien A Fai. Reward circuit connectivity relates to delay discounting in children with attention-deficit/hyperactivity disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 1. 2013-08-19. PMID:23206930. |
we found that functional connectivity of nacc was atypical in children with adhd and the adhd-related increased connectivity between nacc and the prefrontal cortex was associated with greater impulsivity (steeper delayed-reward discounting). |
2013-08-19 |
2023-08-12 |
human |
Taciana G Costa Dias, Vanessa B Wilson, Deepti R Bathula, Swathi P Iyer, Kathryn L Mills, Bria L Thurlow, Corinne A Stevens, Erica D Musser, Samuel D Carpenter, David S Grayson, Suzanne H Mitchell, Joel T Nigg, Damien A Fai. Reward circuit connectivity relates to delay discounting in children with attention-deficit/hyperactivity disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 1. 2013-08-19. PMID:23206930. |
these findings are consistent with the hypothesis that atypical signaling of the nacc to the prefrontal cortex in adhd may lead to excessive approach and failure in estimating future consequences; thus, leading to impulsive behavior. |
2013-08-19 |
2023-08-12 |
human |
A Christakou, C M Murphy, K Chantiluke, A I Cubillo, A B Smith, V Giampietro, E Daly, C Ecker, D Robertson, D G Murphy, K Rubi. Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with autism. Molecular psychiatry. vol 18. issue 2. 2013-08-12. PMID:22290121. |
adhd and asd boys had significantly reduced activation relative to controls in bilateral striato-thalamic regions, left dorsolateral prefrontal cortex (dlpfc) and superior parietal cortex. |
2013-08-12 |
2023-08-12 |
Not clear |
Jen-Tang Cheng, Jay-Shake L. Intra-orbitofrontal cortex injection of haloperidol removes the beneficial effect of methylphenidate on reversal learning of spontaneously hypertensive rats in an attentional set-shifting task. Behavioural brain research. vol 239. 2013-06-04. PMID:23159707. |
furthermore, dysfunctions of prefrontal cortex can impair inhibitory controls of adhd patients, resulting in their impulsive behaviors. |
2013-06-04 |
2023-08-12 |
human |
A Buske-Kirschbaum, J Schmitt, F Plessow, M Romanos, S Weidinger, V Roessne. Psychoendocrine and psychoneuroimmunological mechanisms in the comorbidity of atopic eczema and attention deficit/hyperactivity disorder. Psychoneuroendocrinology. vol 38. issue 1. 2013-05-20. PMID:23141851. |
we propose that the release of inflammatory cytokines caused by the allergic inflammation and/or elevated levels of psychological stress as a result of the chronic disease interfere with the maturation of prefrontal cortex regions and neurotransmitter systems involved adhd pathology. |
2013-05-20 |
2023-08-12 |
Not clear |
Heledd Hart, Joaquim Radua, David Mataix-Cols, Katya Rubi. Meta-analysis of fMRI studies of timing in attention-deficit hyperactivity disorder (ADHD). Neuroscience and biobehavioral reviews. vol 36. issue 10. 2013-05-09. PMID:22922163. |
the most consistent deficits in adhd patients relative to controls were reduced activation in typical areas of timing such as left inferior prefrontal cortex (ifc)/insula, cerebellum, and left inferior parietal lobe. |
2013-05-09 |
2023-08-12 |
Not clear |
Heledd Hart, Joaquim Radua, Tomohiro Nakao, David Mataix-Cols, Katya Rubi. Meta-analysis of functional magnetic resonance imaging studies of inhibition and attention in attention-deficit/hyperactivity disorder: exploring task-specific, stimulant medication, and age effects. JAMA psychiatry. vol 70. issue 2. 2013-04-03. PMID:23247506. |
data synthesis patients with adhd relative to controls showed reduced activation for inhibition in the right inferior frontal cortex, supplementary motor area, and anterior cingulate cortex, as well as striato-thalamic areas, and showed reduced activation for attention in the right dorsolateral prefrontal cortex, posterior basal ganglia, and thalamic and parietal regions. |
2013-04-03 |
2023-08-12 |
human |
Heledd Hart, Joaquim Radua, Tomohiro Nakao, David Mataix-Cols, Katya Rubi. Meta-analysis of functional magnetic resonance imaging studies of inhibition and attention in attention-deficit/hyperactivity disorder: exploring task-specific, stimulant medication, and age effects. JAMA psychiatry. vol 70. issue 2. 2013-04-03. PMID:23247506. |
conclusions patients with adhd have consistent functional abnormalities in 2 distinct domain-dissociated right hemispheric fronto-basal ganglia networks, including the inferior frontal cortex, supplementary motor area, and anterior cingulate cortex for inhibition and dorsolateral prefrontal cortex, parietal, and cerebellar areas for attention. |
2013-04-03 |
2023-08-12 |
human |
Thomas Lempp, Stefan W Toennes, Cora Wunder, Otto Quintus Russe, Christine V Möser, Katharina L Kynast, Christine M Freitag, Ellen Niederberge. Altered gene expression in the prefrontal cortex of young rats induced by the ADHD drug atomoxetine. Progress in neuro-psychopharmacology & biological psychiatry. vol 40. 2013-03-26. PMID:22960082. |
altered gene expression in the prefrontal cortex of young rats induced by the adhd drug atomoxetine. |
2013-03-26 |
2023-08-12 |
rat |
Thomas Lempp, Stefan W Toennes, Cora Wunder, Otto Quintus Russe, Christine V Möser, Katharina L Kynast, Christine M Freitag, Ellen Niederberge. Altered gene expression in the prefrontal cortex of young rats induced by the ADHD drug atomoxetine. Progress in neuro-psychopharmacology & biological psychiatry. vol 40. 2013-03-26. PMID:22960082. |
in summary, we could show that long-term treatment with the adhd drug atomoxetine induces the regulation of several genes in the prefrontal cortex of young rats. |
2013-03-26 |
2023-08-12 |
rat |