| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrea E Spencer, Marie-France Marin, Mohammed R Milad, Thomas J Spencer, Olivia E Bogucki, Amanda L Pope, Natalie Plasencia, Brittany Hughes, Edward F Pace-Schott, Maura Fitzgerald, Mai Uchida, Joseph Biederma. Abnormal fear circuitry in Attention Deficit Hyperactivity Disorder: A controlled magnetic resonance imaging study. Psychiatry research. Neuroimaging. vol 262. 2017-11-16. PMID:28235692. |
compared to healthy controls, adhd subjects had significantly greater insular cortex activation during early extinction, lesser dorsal anterior cingulate cortex (dacc) activation during late extinction, lesser ventromedial prefrontal cortex (vmpfc) activation during late extinction learning and extinction recall, and greater hippocampal activation during extinction recall. |
2017-11-16 |
2023-08-13 |
human |
| Lydia Oikonomidis, Andrea M Santangelo, Yoshiro Shiba, F Hannah Clarke, Trevor W Robbins, Angela C Robert. A dimensional approach to modeling symptoms of neuropsychiatric disorders in the marmoset monkey. Developmental neurobiology. vol 77. issue 3. 2017-10-13. PMID:27589556. |
many of the disorders involve dysfunction within the prefrontal cortex (pfc) and so the marmoset, due to their highly developed pfc and small size, is an ideal species for studying the neurobiological basis of the behavioural dimensions that underlie these symptoms.here we focus on a battery of tests that address dysfunction spanning the cognitive (cognitive inflexibility and working memory), negative valence (fear generalisation and negative bias) and positive valence (anhedonia) systems pertinent for understanding disorders such as adhd, schizophrenia, anxiety, depression and ocd. |
2017-10-13 |
2023-08-13 |
monkey |
| Sofiya Hupalo, Craig W Berridg. Working Memory Impairing Actions of Corticotropin-Releasing Factor (CRF) Neurotransmission in the Prefrontal Cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 11. 2017-08-31. PMID:27272767. |
pfc cognitive dysfunction is implicated in multiple psychopathologies, including attention deficit hyperactivity disorder (adhd). |
2017-08-31 |
2023-08-13 |
rat |
| G A Ünal, A N İnci Kenar, E Tepeli, Y Kıroğlu, H Herke. Relationship between the SNAP-25 gene and the effects of methylphenidate on the anterior cingulate cortex of patients with adult attention deficit hyperactivity disorder: a magnetic resonance spectroscopy study. European review for medical and pharmacological sciences. vol 20. issue 11. 2017-08-22. PMID:27338073. |
thus, the present study aimed to determine the relationship between changes in creatine (cr), choline (cho), and n-acetyl aspartate (naa) levels in the prefrontal cortex (pfc) and anterior cingulate cortex (acc) of adults with adhd and the snap-25 gene polymorphism following the use of mph. |
2017-08-22 |
2023-08-13 |
Not clear |
| Tohru Kodama, Takashi Kojima, Yoshiko Honda, Takayuki Hosokawa, Ken-Ichiro Tsutsui, Masataka Watanab. Oral Administration of Methylphenidate (Ritalin) Affects Dopamine Release Differentially Between the Prefrontal Cortex and Striatum: A Microdialysis Study in the Monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 9. 2017-08-18. PMID:28154152. |
however, adhd patients show impaired prefrontal cortex (pfc) function and mph administration is associated with increased neural activity in the pfc. |
2017-08-18 |
2023-08-13 |
human |
| A N Inci Kenar, G A Unal, Y Kiroglu, H Herke. Effects of methylphenidate treatment on the cerebellum in adult attention-deficit hyperactivity disorder: a magnetic resonance spectroscopy study. European review for medical and pharmacological sciences. vol 21. issue 2. 2017-07-24. PMID:28165547. |
this study investigated the relationship between the use of methylphenidate (mph) and changes in creatine, choline, and n-acetyl-aspartate (naa) in the dorsolateral prefrontal cortex (dlpfc), striatum, cerebellum, and anterior cingulate cortex (acc) in adults with attention-deficit hyperactivity disorder (adhd). |
2017-07-24 |
2023-08-13 |
Not clear |
| Ike Dela Peña, Wei-Xing Sh. Chemogenetic approach to model hypofrontality. Medical hypotheses. vol 93. 2017-06-15. PMID:27372868. |
clinical evidence suggests that the prefrontal cortex (pfc) is hypofunctional in disorders including schizophrenia, drug addiction, and attention-deficit/hyperactivity disorder (adhd). |
2017-06-15 |
2023-08-13 |
Not clear |
| Huey-Ling Chiang, Yu-Jen Chen, Yu-Chun Lo, Wen-Yih I Tseng, Susan S Ga. Altered white matter tract property related to impaired focused attention, sustained attention, cognitive impulsivity and vigilance in attention-deficit/ hyperactivity disorder. Journal of psychiatry & neuroscience : JPN. vol 40. issue 5. 2016-12-13. PMID:25871496. |
we sought to compare the microstructural property of fibre tracts associated with the prefrontal cortex and its association with adhd symptoms and a wide range of attention performance in youth with adhd and healthy controls. |
2016-12-13 |
2023-08-13 |
Not clear |
| J Jin, L Liu, Q Gao, R C K Chan, H Li, Y Chen, Y Wang, Q Qia. The divergent impact of COMT Val158Met on executive function in children with and without attention-deficit/hyperactivity disorder. Genes, brain, and behavior. vol 15. issue 2. 2016-12-13. PMID:26560848. |
children with attention-deficit/hyperactivity disorder (adhd) usually display deficits in executive function (ef), which are primarily mediated by prefrontal cortex (pfc). |
2016-12-13 |
2023-08-13 |
Not clear |
| A N Inci Kenar, G A Ünal, H Güler, B Albuz, Y Kıroğlu, M E Erdal, H Herke. Relationship between the DAT1 gene and the effects of methylphenidate administration in adult attention deficit hyperactivity disorder: a magnetic resonance spectroscopy study. European review for medical and pharmacological sciences. vol 20. issue 7. 2016-12-13. PMID:27097961. |
this study investigated the relationship between dat1 gene polymorphisms and the effects of methylphenidate (mph) administration on n-acetyl aspartate (naa), creatine (cr), and choline (cho) levels in the anterior cingulate cortex, prefrontal cortex, striatum, and cerebellum in adult patients with attention deficit hyperactivity disorder (adhd). |
2016-12-13 |
2023-08-13 |
Not clear |
| Nick Ortiz, Aisling Parsons, Robert Whelan, Katie Brennan, Maria L F Agan, Redmond O'Connell, Jessica Bramham, Hugh Garava. Decreased frontal, striatal and cerebellar activation in adults with ADHD during an adaptive delay discounting task. Acta neurobiologiae experimentalis. vol 75. issue 3. 2016-11-08. PMID:26581388. |
however, adults with adhd showed less task activation in a number of regions including the dorsolateral prefrontal cortex, superior frontal gyrus, anterior cingulate, caudate nucleus and declive of the cerebellum. |
2016-11-08 |
2023-08-13 |
human |
| Hsiang-Yuan Lin, Wen-Yih Isaac Tseng, Meng-Chuan Lai, Kayako Matsuo, Susan Shur-Fen Ga. Altered resting-state frontoparietal control network in children with attention-deficit/hyperactivity disorder. Journal of the International Neuropsychological Society : JINS. vol 21. issue 4. 2016-11-01. PMID:25928822. |
involvement of the frontoparietal control network based on the anterior prefrontal cortex in neurobiological mechanisms of adhd has yet to be tested. |
2016-11-01 |
2023-08-13 |
human |
| Hsiang-Yuan Lin, Wen-Yih Isaac Tseng, Meng-Chuan Lai, Kayako Matsuo, Susan Shur-Fen Ga. Altered resting-state frontoparietal control network in children with attention-deficit/hyperactivity disorder. Journal of the International Neuropsychological Society : JINS. vol 21. issue 4. 2016-11-01. PMID:25928822. |
compared with td children, children with adhd demonstrated weaker connectivity between the right anterior prefrontal cortex (pfc) and the right ventrolateral pfc, and between the left anterior pfc and the right inferior parietal lobule. |
2016-11-01 |
2023-08-13 |
human |
| Daniel W Bryden, Amanda C Burton, Brian R Barnett, Valerie J Cohen, Taylor N Hearn, Emily A Jones, Reshma J Kariyil, Alice Kunin, Sae In Kwak, Jessica Lee, Brooke L Lubinski, Gautam K Rao, Ashley Zhan, Matthew R Roesc. Prenatal Nicotine Exposure Impairs Executive Control Signals in Medial Prefrontal Cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 3. 2016-10-06. PMID:26189451. |
current literature suggests that core deficits observed in adhd reflect abnormal inhibitory control governed by the prefrontal cortex. |
2016-10-06 |
2023-08-13 |
rat |
| Ping Zhong, Wenhua Liu, Zhen Ya. Aberrant regulation of synchronous network activity by the attention-deficit/hyperactivity disorder-associated human dopamine D4 receptor variant D4.7 in the prefrontal cortex. The Journal of physiology. vol 594. issue 1. 2016-10-05. PMID:26541360. |
methylphenidate, a psychostimulant drug used to treat adhd, normalized the effects of hd4.7 on synchronous network bursts in pfc pyramidal neurons. |
2016-10-05 |
2023-08-13 |
mouse |
| Ping Zhong, Wenhua Liu, Zhen Ya. Aberrant regulation of synchronous network activity by the attention-deficit/hyperactivity disorder-associated human dopamine D4 receptor variant D4.7 in the prefrontal cortex. The Journal of physiology. vol 594. issue 1. 2016-10-05. PMID:26541360. |
the findings of the present study suggest that the aberrant regulation of pfc synchronous network activity by hd4.7 may underlie its involvement in adhd. |
2016-10-05 |
2023-08-13 |
mouse |
| Ping Zhong, Wenhua Liu, Zhen Ya. Aberrant regulation of synchronous network activity by the attention-deficit/hyperactivity disorder-associated human dopamine D4 receptor variant D4.7 in the prefrontal cortex. The Journal of physiology. vol 594. issue 1. 2016-10-05. PMID:26541360. |
methylphenidate, a psychostimulant drug used to treat adhd, normalized the effects of hd4.7 on synchronous network bursts in pfc pyramidal neurons. |
2016-10-05 |
2023-08-13 |
mouse |
| Ping Zhong, Wenhua Liu, Zhen Ya. Aberrant regulation of synchronous network activity by the attention-deficit/hyperactivity disorder-associated human dopamine D4 receptor variant D4.7 in the prefrontal cortex. The Journal of physiology. vol 594. issue 1. 2016-10-05. PMID:26541360. |
it is suggested that the aberrant regulation of pfc network activity by hd4.7 may underlie its involvement in adhd. |
2016-10-05 |
2023-08-13 |
mouse |
| Malligurki Raghurama Rukmani, Shekhar P Seshadri, Kandavel Thennarasu, Trichur R Raju, Talakad N Sathyaprabh. Heart Rate Variability in Children with Attention-Deficit/Hyperactivity Disorder: A Pilot Study. Annals of neurosciences. vol 23. issue 2. 2016-09-20. PMID:27647958. |
the prefrontal cortex, which is vital for attention, motor control, emotional regulation and higher order autonomic control, is hypofunctional in adhd. |
2016-09-20 |
2023-08-13 |
Not clear |
| Maria Luz Gonzalez-Gadea, Srivas Chennu, Tristan A Bekinschtein, Alexia Rattazzi, Ana Beraudi, Paula Tripicchio, Beatriz Moyano, Yamila Soffita, Laura Steinberg, Federico Adolfi, Mariano Sigman, Julian Marino, Facundo Manes, Agustin Ibane. Predictive coding in autism spectrum disorder and attention deficit hyperactivity disorder. Journal of neurophysiology. vol 114. issue 5. 2016-09-15. PMID:26311184. |
in contrast, children with adhd exhibited reduced cortical responses in superior fc to expected events but strong pfc activation to unexpected events. |
2016-09-15 |
2023-08-13 |
human |