| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jochen Bauer, Anne Werner, Waldemar Kohl, Harald Kugel, Anna Shushakova, Anya Pedersen, Patricia Ohrman. Hyperactivity and impulsivity in adult attention-deficit/hyperactivity disorder is related to glutamatergic dysfunction in the anterior cingulate cortex. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 19. issue 7. 2019-01-14. PMID:27973969. |
impulsivity, a core symptom in patients with adhd, has been repeatedly associated with glutamatergic neurotransmission, and pharmacological treatment of adhd has been shown to reduce glutamate levels in the prefrontal cortex. |
2019-01-14 |
2023-08-13 |
Not clear |
| Vincent Chin-Hung Chen, Chun-Ching Chiu, Li-Jeng Chen, Tsai-Ching Hsu, Bor-Show Tzan. Effects of taurine on striatal dopamine transporter expression and dopamine uptake in SHR rats. Behavioural brain research. vol 348. 2018-11-05. PMID:29694913. |
dopaminergic deficits in the prefrontal cortex and striatum have been attributed to the pathogenesis of attention-deficit hyperactivity disorder (adhd). |
2018-11-05 |
2023-08-13 |
rat |
| Yue Gu, Shuo Miao, Junxia Han, Ke Zeng, Gaoxiang Ouyang, Jian Yang, Xiaoli L. Complexity analysis of fNIRS signals in ADHD children during working memory task. Scientific reports. vol 7. issue 1. 2018-09-18. PMID:28400568. |
we found that pe values exhibited significantly negative correlation with the cortical activations (r = -0.515, p = 0.003), and the pe values of right dorsolateral prefrontal cortex in adhd children were significantly larger than those in normal controls (p = 0.027). |
2018-09-18 |
2023-08-13 |
Not clear |
| Yue Gu, Shuo Miao, Junxia Han, Ke Zeng, Gaoxiang Ouyang, Jian Yang, Xiaoli L. Complexity analysis of fNIRS signals in ADHD children during working memory task. Scientific reports. vol 7. issue 1. 2018-09-18. PMID:28400568. |
in addition, the pe values of right dorsolateral prefrontal cortex were positively correlated to the adhd index (r = 0.448, p = 0.012). |
2018-09-18 |
2023-08-13 |
Not clear |
| Shiva Khoshnoud, Mohammad Ali Nazari, Mousa Shams. Functional brain dynamic analysis of ADHD and control children using nonlinear dynamical features of EEG signals. Journal of integrative neuroscience. vol 17. issue 1. 2018-08-16. PMID:29172003. |
further, mean approximate entropy was significantly lower in adhd subjects in prefrontal cortex. |
2018-08-16 |
2023-08-13 |
human |
| Anna Sotnikova, Cornelia Soff, Enzo Tagliazucchi, Katja Becker, Michael Siniatchki. Transcranial Direct Current Stimulation Modulates Neuronal Networks in Attention Deficit Hyperactivity Disorder. Brain topography. vol 30. issue 5. 2018-07-27. PMID:28213645. |
since patients with attention deficit hyperactivity disorder (adhd) are characterized by both underactivation of the prefrontal cortex and deficits in wm, the modulation of prefrontal activity with tdcs in adhd patients may increase their wm performance as well as improve the activation and connectivity of the wm network. |
2018-07-27 |
2023-08-13 |
Not clear |
| Anna Sotnikova, Cornelia Soff, Enzo Tagliazucchi, Katja Becker, Michael Siniatchki. Transcranial Direct Current Stimulation Modulates Neuronal Networks in Attention Deficit Hyperactivity Disorder. Brain topography. vol 30. issue 5. 2018-07-27. PMID:28213645. |
after randomization, sixteen adolescents with adhd underwent either anodal tdcs over the left dorsolateral prefrontal cortex (dlpfc, 1 ma, 20 min) or sham stimulation with simultaneous fmri during n-back wm task. |
2018-07-27 |
2023-08-13 |
Not clear |
| Jia Cheng, Aiyi Liu, Michael Y Shi, Zhen Ya. Disrupted Glutamatergic Transmission in Prefrontal Cortex Contributes to Behavioral Abnormality in an Animal Model of ADHD. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 10. 2018-04-24. PMID:28176786. |
disrupted glutamatergic transmission in prefrontal cortex contributes to behavioral abnormality in an animal model of adhd. |
2018-04-24 |
2023-08-13 |
rat |
| Jia Cheng, Aiyi Liu, Michael Y Shi, Zhen Ya. Disrupted Glutamatergic Transmission in Prefrontal Cortex Contributes to Behavioral Abnormality in an Animal Model of ADHD. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 10. 2018-04-24. PMID:28176786. |
these results suggest that the disrupted function of ampars in pfc may underlie the behavioral deficits in adolescent shr and enhancing pfc activity could be a treatment strategy for adhd. |
2018-04-24 |
2023-08-13 |
rat |
| Kurt P Schulz, Xiaobo Li, Suzanne M Clerkin, Jin Fan, Olga G Berwid, Jeffrey H Newcorn, Jeffrey M Halperi. Prefrontal and parietal correlates of cognitive control related to the adult outcome of attention-deficit/hyperactivity disorder diagnosed in childhood. Cortex; a journal devoted to the study of the nervous system and behavior. vol 90. 2018-03-22. PMID:28292705. |
the protracted and highly variable development of prefrontal cortex regions that support cognitive control has been purported to shape the adult outcome of attention-deficit/hyperactivity disorder (adhd). |
2018-03-22 |
2023-08-13 |
human |
| Luke J Norman, Christina O Carlisi, Anastasia Christakou, Ana Cubillo, Clodagh M Murphy, Kaylita Chantiluke, Andrew Simmons, Vincent Giampietro, Michael Brammer, David Mataix-Cols, Katya Rubi. Shared and disorder-specific task-positive and default mode network dysfunctions during sustained attention in paediatric Attention-Deficit/Hyperactivity Disorder and obsessive/compulsive disorder. NeuroImage. Clinical. vol 15. 2018-03-09. PMID:28529874. |
adhd and ocd patients shared left insula/ventral ifg underactivation and increased activation in posterior default mode network relative to controls, but had disorder-specific overactivation in anterior default mode regions, in dorsal anterior cingulate for adhd and in anterior ventromedial prefrontal cortex for ocd. |
2018-03-09 |
2023-08-13 |
Not clear |
| Michie Odle, Judith A Ouellett. Anticipatory Electrodermal Response as a Differentiating Somatic Marker Between Children with ADHD and Controls. Applied psychophysiology and biofeedback. vol 41. issue 4. 2018-03-05. PMID:27272970. |
results indicate that the adhd group exhibited significantly lower autonomic reactivity to anticipated consequences, evidencing a neuropsychological profile similar to patients with lesions in the ventromedial prefrontal cortex. |
2018-03-05 |
2023-08-13 |
Not clear |
| Analucia A Alegria, Melanie Wulff, Helen Brinson, Gareth J Barker, Luke J Norman, Daniel Brandeis, Daniel Stahl, Anthony S David, Eric Taylor, Vincent Giampietro, Katya Rubi. Real-time fMRI neurofeedback in adolescents with attention deficit hyperactivity disorder. Human brain mapping. vol 38. issue 6. 2018-03-01. PMID:28342214. |
a randomized controlled trial tested the efficacy of rtfmri-nf of right inferior prefrontal cortex (rifg), a key region that is compromised in adhd and upregulated with psychostimulants, on improvement of adhd symptoms, cognition, and inhibitory fmri activation. |
2018-03-01 |
2023-08-13 |
human |
| Cornelia Soff, Anna Sotnikova, Hanna Christiansen, Katja Becker, Michael Siniatchki. Transcranial direct current stimulation improves clinical symptoms in adolescents with attention deficit hyperactivity disorder. Journal of neural transmission (Vienna, Austria : 1996). vol 124. issue 1. 2018-02-27. PMID:27853926. |
as patients with attention deficit hyperactivity disorder (adhd) are characterized by both underactivation of the prefrontal cortex and deficits in working memory that correlate with clinical symptoms, it is hypothesized that the modulation of prefrontal activity with tdcs in patients with adhd increases performance in working memory and reduces symptoms of adhd. |
2018-02-27 |
2023-08-13 |
Not clear |
| Cornelia Soff, Anna Sotnikova, Hanna Christiansen, Katja Becker, Michael Siniatchki. Transcranial direct current stimulation improves clinical symptoms in adolescents with attention deficit hyperactivity disorder. Journal of neural transmission (Vienna, Austria : 1996). vol 124. issue 1. 2018-02-27. PMID:27853926. |
to test this hypothesis, fifteen adolescents with adhd (12-16 years old, three girls and 12 boys) were treated according to the randomized, double-blinded, sham-controlled, crossover design with either 1 ma anodal tdcs over the left dorsolateral prefrontal cortex or with the sham protocol 5 days each with a 2 weeks pause between these conditions. |
2018-02-27 |
2023-08-13 |
Not clear |
| Li Hui Wu, Wei Cheng, Mei Yu, Bao Mei He, Hui Sun, Qi Chen, Yi Wei Dong, Xiao Ting Shao, Qian Qian Cai, Min Peng, Xing Zhong W. Nr3C1-Bhlhb2 Axis Dysregulation Is Involved in the Development of Attention Deficit Hyperactivity. Molecular neurobiology. vol 54. issue 2. 2018-02-13. PMID:26820676. |
to investigate the key regulators in the prefrontal cortex (pfc), the major affected areas of adhd, microrna (mir)-138,138*, 34c*, 296, and 494, were noted for their significant downregulation in adhd model rats spontaneously hypertensive rats (shrs) compared to wistar kyoto (wky) rat control. |
2018-02-13 |
2023-08-13 |
rat |
| Li Hui Wu, Wei Cheng, Mei Yu, Bao Mei He, Hui Sun, Qi Chen, Yi Wei Dong, Xiao Ting Shao, Qian Qian Cai, Min Peng, Xing Zhong W. Nr3C1-Bhlhb2 Axis Dysregulation Is Involved in the Development of Attention Deficit Hyperactivity. Molecular neurobiology. vol 54. issue 2. 2018-02-13. PMID:26820676. |
in the pfc of adhd model rats shr, nr3c1 expression was abnormally elevated and reversely correlated with the levels of mir-138-1, 34c, 296, and 494 expression. |
2018-02-13 |
2023-08-13 |
rat |
| Li Hui Wu, Wei Cheng, Mei Yu, Bao Mei He, Hui Sun, Qi Chen, Yi Wei Dong, Xiao Ting Shao, Qian Qian Cai, Min Peng, Xing Zhong W. Nr3C1-Bhlhb2 Axis Dysregulation Is Involved in the Development of Attention Deficit Hyperactivity. Molecular neurobiology. vol 54. issue 2. 2018-02-13. PMID:26820676. |
consistently, bhlhb2 expression was significantly higher in pfc of adhd model shr than control. |
2018-02-13 |
2023-08-13 |
rat |
| I J I Dela Peña, I Dela Peña, J B de la Peña, H J Kim, A Sohn, C Y Shin, D H Han, B-N Kim, J H Ryu, J H Cheon. Transcriptional profiling of SHR/NCrl prefrontal cortex shows hyperactivity-associated genes responsive to amphetamine challenge. Genes, brain, and behavior. vol 16. issue 7. 2017-12-22. PMID:28422445. |
to this end, we examined differentially expressed genes (degs) in the prefrontal cortex (pfc) of shr/ncrl, an animal model of adhd, compared with its genetic control, the wistar kyoto (wky/ncrl) rat and the wistar rat, strain used to represent the 'normal' heterogeneous population. |
2017-12-22 |
2023-08-13 |
rat |
| Igor Dórea Bandeira, Rachel Silvany Quadros Guimarães, João Gabriel Jagersbacher, Thiago Lima Barretto, Jéssica Regina de Jesus-Silva, Samantha Nunes Santos, Nayara Argollo, Rita Lucen. Transcranial Direct Current Stimulation in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD): A Pilot Study. Journal of child neurology. vol 31. issue 7. 2017-12-20. PMID:26879095. |
studies investigating the possible benefits of transcranial direct current stimulation on left dorsolateral prefrontal cortex in children and adolescents with attention-deficit hyperactivity disorder (adhd) have not been performed. |
2017-12-20 |
2023-08-13 |
human |