| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| YogendraSinh H Raol, Ingrid V Lund, Sabita Bandyopadhyay, Guojun Zhang, Daniel S Roberts, John H Wolfe, Shelley J Russek, Amy R Brooks-Kaya. Enhancing GABA(A) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 44. 2006-11-14. PMID:17079662. |
differential expression of gaba(a) receptor (gabr) subunits has been demonstrated in hippocampus from patients and animals with temporal lobe epilepsy (tle), but whether these changes are important for epileptogenesis remains unknown. |
2006-11-14 |
2023-08-12 |
rat |
| Tih-Shih Lee, Lars Petter Bjørnsen, Carlos Paz, Jung H Kim, Susan S Spencer, Dennis D Spencer, Tore Eid, Nihal C de Laneroll. GAT1 and GAT3 expression are differently localized in the human epileptogenic hippocampus. Acta neuropathologica. vol 111. issue 4. 2006-08-24. PMID:16456667. |
the gamma amino butyric acid (gaba) transporters gat-1 and gat-3 were localized by immunohistochemistry in hippocampi removed for the control of medically intractable temporal lobe epilepsy (tle). |
2006-08-24 |
2023-08-12 |
human |
| E Palma, M Amici, F Sobrero, G Spinelli, S Di Angelantonio, D Ragozzino, A Mascia, C Scoppetta, V Esposito, R Miledi, F Euseb. Anomalous levels of Cl- transporters in the hippocampal subiculum from temporal lobe epilepsy patients make GABA excitatory. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 22. 2006-07-26. PMID:16709666. |
anomalous levels of cl- transporters in the hippocampal subiculum from temporal lobe epilepsy patients make gaba excitatory. |
2006-07-26 |
2023-08-12 |
human |
| Elisabeth Stogmann, Alexander Zimprich, Christoph Baumgartner, Andreas Gleiss, Fritz Zimpric. Lack of association between a GABA receptor 1 gene polymorphism and temporal lobe epilepsy. Epilepsia. vol 47. issue 2. 2006-05-02. PMID:16499773. |
lack of association between a gaba receptor 1 gene polymorphism and temporal lobe epilepsy. |
2006-05-02 |
2023-08-12 |
Not clear |
| Holger A Volk, Dimitrula Arabadzisz, Jean-Marc Fritschy, Claudia Brandt, Kerstin Bethmann, Wolfgang Lösche. Antiepileptic drug-resistant rats differ from drug-responsive rats in hippocampal neurodegeneration and GABA(A) receptor ligand binding in a model of temporal lobe epilepsy. Neurobiology of disease. vol 21. issue 3. 2006-04-28. PMID:16256358. |
antiepileptic drug-resistant rats differ from drug-responsive rats in hippocampal neurodegeneration and gaba(a) receptor ligand binding in a model of temporal lobe epilepsy. |
2006-04-28 |
2023-08-12 |
rat |
| Maria Elisa Calcagnotto, Mercedes F Paredes, Tarik Tihan, Nicholas M Barbaro, Scott C Baraba. Dysfunction of synaptic inhibition in epilepsy associated with focal cortical dysplasia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 42. 2006-03-15. PMID:16237169. |
in patients with temporal lobe epilepsy and in several animal models, compromised neuronal inhibition, mediated by gaba, contributes to seizure genesis. |
2006-03-15 |
2023-08-12 |
human |
| Liankun Ren, Liri Jin, Boyu Zhang, Yanbin Jia, Liwen Wu, Yan She. Lack of GABABR1 gene variation (G1465A) in a Chinese population with temporal lobe epilepsy. Seizure. vol 14. issue 8. 2006-02-21. PMID:16278087. |
gaba(b) receptor1 (gaba(b)r1) gene is one of the susceptibility genes for temporal lobe epilepsy (tle). |
2006-02-21 |
2023-08-12 |
Not clear |
| D Ragozzino, E Palma, S Di Angelantonio, M Amici, A Mascia, A Arcella, F Giangaspero, G Cantore, G Di Gennaro, M Manfredi, V Esposito, P P Quarato, R Miledi, F Euseb. Rundown of GABA type A receptors is a dysfunction associated with human drug-resistant mesial temporal lobe epilepsy. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 42. 2005-12-05. PMID:16217016. |
rundown of gaba type a receptors is a dysfunction associated with human drug-resistant mesial temporal lobe epilepsy. |
2005-12-05 |
2023-08-12 |
human |
| D Ragozzino, E Palma, S Di Angelantonio, M Amici, A Mascia, A Arcella, F Giangaspero, G Cantore, G Di Gennaro, M Manfredi, V Esposito, P P Quarato, R Miledi, F Euseb. Rundown of GABA type A receptors is a dysfunction associated with human drug-resistant mesial temporal lobe epilepsy. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 42. 2005-12-05. PMID:16217016. |
we find that when cell membranes, isolated from the temporal neocortex of patients afflicted with drug-resistant mesial temporal lobe epilepsy (tle), are injected into frog oocytes they acquire gaba type a receptors (gaba(a)-receptors) that display a marked rundown during repetitive applications of gaba. |
2005-12-05 |
2023-08-12 |
human |
| T Nishimura, C Schwarzer, E Gasser, N Kato, A Vezzani, G Sper. Altered expression of GABA(A) and GABA(B) receptor subunit mRNAs in the hippocampus after kindling and electrically induced status epilepticus. Neuroscience. vol 134. issue 2. 2005-11-15. PMID:15951123. |
changes in the expression of gaba(a) and gaba(b) receptor mrnas were observed in both models, and compared with those seen in other models and in human temporal lobe epilepsy. |
2005-11-15 |
2023-08-12 |
human |
| S R Kleppner, A J Tobi. GABA signalling: therapeutic targets for epilepsy, Parkinson's disease and Huntington's disease. Expert opinion on therapeutic targets. vol 5. issue 2. 2005-07-19. PMID:15992178. |
temporal lobe epilepsy (tle), parkinson's disease (pd) and huntington's disease (hd) are neurodegenerative disorders that involve disruptions in gamma-amino butyric acid (gaba) signalling. |
2005-07-19 |
2023-08-12 |
Not clear |
| Annick Salzmann, Bruno Moulard, Arielle Crespel, Michel Baldy-Moulinier, Catherine Buresi, Alain Malafoss. GABA receptor 1 polymorphism (G1465A) and temporal lobe epilepsy. Epilepsia. vol 46. issue 6. 2005-06-30. PMID:15946333. |
gaba receptor 1 polymorphism (g1465a) and temporal lobe epilepsy. |
2005-06-30 |
2023-08-12 |
Not clear |
| Annick Salzmann, Bruno Moulard, Arielle Crespel, Michel Baldy-Moulinier, Catherine Buresi, Alain Malafoss. GABA receptor 1 polymorphism (G1465A) and temporal lobe epilepsy. Epilepsia. vol 46. issue 6. 2005-06-30. PMID:15946333. |
to reevaluate the genetic contribution of the polymorphism g1465a of the gene coding for gamma-aminobutyric acid (gaba)(b) receptor 1 subunit [gaba(b)(1)] in a sample of french patients with temporal lobe epilepsy (tle) and to perform an exploratory analysis in other phenotypic subgroups. |
2005-06-30 |
2023-08-12 |
Not clear |
| Joshua T Kantrowitz, N Noelle Francis, Alejandro Salah, Katherine L Perkin. Synaptic depolarizing GABA Response in adults is excitatory and proconvulsive when GABAB receptors are blocked. Journal of neurophysiology. vol 93. issue 5. 2005-06-13. PMID:15590725. |
loss of gaba(b) receptor function is associated with temporal lobe epilepsy in rodents and humans. |
2005-06-13 |
2023-08-12 |
Not clear |
| Nigel C K Tan, Sarah E Heron, Ingrid E Scheffer, Samuel F Berkovic, John C Mulle. Is variation in the GABA(B) receptor 1 gene associated with temporal lobe epilepsy? Epilepsia. vol 46. issue 5. 2005-06-01. PMID:15857448. |
is variation in the gaba(b) receptor 1 gene associated with temporal lobe epilepsy? |
2005-06-01 |
2023-08-12 |
Not clear |
| Nigel C K Tan, Sarah E Heron, Ingrid E Scheffer, Samuel F Berkovic, John C Mulle. Is variation in the GABA(B) receptor 1 gene associated with temporal lobe epilepsy? Epilepsia. vol 46. issue 5. 2005-06-01. PMID:15857448. |
an association between the c.1465g-->a variant in the gaba(b) receptor 1 gene (gabbr1) and susceptibility to temporal lobe epilepsy (tle) has been reported in an italian cohort. |
2005-06-01 |
2023-08-12 |
Not clear |
| Zechun Peng, Christine S Huang, Brandon M Stell, Istvan Mody, Carolyn R House. Altered expression of the delta subunit of the GABAA receptor in a mouse model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 39. 2005-04-14. PMID:15456836. |
the findings support the idea that alterations in nonsynaptic delta subunit-containing gaba(a) receptors in both principal cells and interneurons could contribute to increased seizure susceptibility in the hippocampal formation in a temporal lobe epilepsy model. |
2005-04-14 |
2023-08-12 |
mouse |
| Claire Leroy, Pierrick Poisbeau, A Florence Keller, Astrid Nehli. Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy. The Journal of physiology. vol 557. issue Pt 2. 2005-01-05. PMID:15034126. |
pharmacological plasticity of gaba(a) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy. |
2005-01-05 |
2023-08-12 |
rat |
| Claire Leroy, Pierrick Poisbeau, A Florence Keller, Astrid Nehli. Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy. The Journal of physiology. vol 557. issue Pt 2. 2005-01-05. PMID:15034126. |
in the lithium-pilocarpine model (li-pilocarpine) of temporal lobe epilepsy, gaba(a) receptor-mediated inhibitory postsynaptic currents (gaba(a) ipscs) were recorded in dentate gyrus granule cells (gcs) from adult rat hippocampal slices. |
2005-01-05 |
2023-08-12 |
rat |
| Günther Sperk, Sabine Furtinger, Christoph Schwarzer, Susanne Pirke. GABA and its receptors in epilepsy. Advances in experimental medicine and biology. vol 548. 2004-08-17. PMID:15250588. |
in animal epilepsy models and in tissue from patients with temporal lobe epilepsy, loss in subsets of hippocampal gaba neurons is observed. |
2004-08-17 |
2023-08-12 |
Not clear |