| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ngoc-Han Thi Nguyen, Ji Hun Kim, Su-Min Lee, Byung-Kwan Cho, Yang-Hoon Kim, Jiho Mi. Inhibition of Tau Phosphorylation and Aβ Accumulation by S. cerevisiae-derived Vacuoles in LPS-Induced SH-SY5Y Cells. Journal of biotechnology. 2023-09-30. PMID:37777088. |
neurodegenerative diseases, such as alzheimer's disease (ad), are characterized by the accumulation of intracellular tau and amyloid beta (aβ) proteins, which lead to neuroinflammation and neuronal apoptosis. |
2023-09-30 |
2023-10-07 |
Not clear |
| Yang Liu, Wen Guo, Si-Lu Hon. Aerobic exercise mitigates hippocampal neuronal apoptosis by regulating DAPK1/CDKN2A/REDD1/FoXO1/FasL signaling pathway in D-galactose-induced aging mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 10. 2023-09-28. PMID:37768886. |
in the present study, we investigated the impact of aerobic exercise on hippocampal neuronal apoptosis in aging mice and the potential involvement of dapk1 and its downstream pathways based on recent data that dapk1 may be associated with neuronal death in neurodegenerative diseases. |
2023-09-28 |
2023-10-07 |
mouse |
| Jinhua Li, Yarong Wu, Shuze Dong, Ye Yu, Yuhao Wu, Benhan Xiang, Qin L. Research Progress on Neuroprotective Effects of Isoquinoline Alkaloids. Molecules (Basel, Switzerland). vol 28. issue 12. 2023-06-28. PMID:37375352. |
neuronal injury and apoptosis are important causes of the occurrence and development of many neurodegenerative diseases, such as cerebral ischemia, alzheimer's disease, and parkinson's disease. |
2023-06-28 |
2023-08-14 |
Not clear |
| Ahmi Öz, Ömer Çeli. Downregulation of TRPM7, TRPM8, and TRPV1 channels modulate apoptotic parameters and neurodegenerative markers: Focus on neuronal differentiation and Parkinson's disease model. Cell biology international. 2023-05-20. PMID:37208975. |
the transient receptor potential channel (trp) channels are expressed in neuronal tissues and involved in neurological diseases such as pain, epilepsy, neuronal apoptosis, and neurodegenerative diseases. |
2023-05-20 |
2023-08-14 |
Not clear |
| Wenyuan Zhang, Songjuan Zhuang, Hui Guan, Feng Li, Hui Zou, Dapeng L. New insights into the anti-apoptotic mechanism of natural polyphenols in complex with Bax protein. Journal of biomolecular structure & dynamics. 2023-05-15. PMID:37184126. |
excessive apoptosis can kill normal cells and lead to liver damage, heart failure and neurodegenerative diseases. |
2023-05-15 |
2023-08-14 |
Not clear |
| Alexey M Nesterenko, Dmitry A Korzhenevskii, Vasilisa M Tereshchuk, Olga M Kudryashova, Vsevolod V Belousov, Arina G Shokhin. Dataset on the proteomic response during ferroptosis induction via tamoxifen induced GPX4 KO in mouse embryonic fibroblasts. Data in brief. vol 48. 2023-05-11. PMID:37168593. |
ferroptosis is a type of programmed cell death distinct from apoptosis and necroptosis that plays an essential role in pathophysiological conditions such as neurodegenerative diseases and tumorigenesis. |
2023-05-11 |
2023-08-14 |
mouse |
| Haiqing Bu, Zhijia Li, Yingying Lu, Zhiyao Zhuang, Yongqi Zhen, Lan Zhan. Deciphering the multifunctional role of dual leucine zipper kinase (DLK) and its therapeutic potential in disease. European journal of medicinal chemistry. vol 255. 2023-04-25. PMID:37098296. |
importantly, dlk is closely related to the pathogenesis of numerous neurodegenerative diseases and the induction of β-cell apoptosis that leads to diabetes. |
2023-04-25 |
2023-08-14 |
human |
| Feng Qiu, Yue Wu, Guojin Xie, Hui Cao, Mingyang Du, Haibo Jian. MiRNA-1976 Regulates the Apoptosis of Dopaminergic Neurons by Targeting the Journal of integrative neuroscience. vol 22. issue 2. 2023-03-30. PMID:36992582. |
mirna-1976 regulates the apoptosis of dopaminergic neurons by targeting the parkinson's disease (pd), which is a neurodegenerative disease, requires urgently needed biomarkers to explore its mechanism. |
2023-03-30 |
2023-08-14 |
Not clear |
| Christina Magdy Wadie, Radwa Hassan Ali, Abd El-Hamid A Mohamed, Jolly M W Labib, Abdel Rhman Sabaa, Hossam Eldin Ahmed Awad, Doaa Ahmed Abou-Bak. A comparative study of acetyl-l-carnitine and caloric restriction impact on hippocampal autophagy, apoptosis, neurogenesis, and astroglial function in AlCl Canadian journal of physiology and pharmacology. 2023-03-29. PMID:36988119. |
a comparative study of acetyl-l-carnitine and caloric restriction impact on hippocampal autophagy, apoptosis, neurogenesis, and astroglial function in alcl alzheimer's disease (ad) is a worldwide chronic progressive neurodegenerative disease. |
2023-03-29 |
2023-08-14 |
Not clear |
| Qiao Xiao, Huina Liu, Chao Yang, Yi Chen, Yueyue Huang, Xiaoxia Xiao, Yaru Pan, Jinyang He, Qun Du, Qi Wang, Yifan Zhan. Bushen-Yizhi formula exerts neuroprotective effect via inhibiting excessive mitophagy in rats with chronic cerebral hypoperfusion. Journal of ethnopharmacology. 2023-03-10. PMID:36898450. |
bushen-yizhi formula (bsyz), a traditional chinese medicine (tcm) prescription widely used in treating mental retardation and neurodegenerative diseases with kidney deficiency, has been reported to attenuate oxidative stress-related neuronal apoptosis. |
2023-03-10 |
2023-08-14 |
rat |
| Maryam Akhavan Tavakoli, Maryam Soleimani, Hassan Marzban, Ronak Shabani, Fatemeh Moradi, Marziyeh Ajdary, Mehdi Mehdizade. Autophagic Molecular Alterations in the Mouse Cerebellum Experimental Autoimmune Encephalomyelitis Model Following Treatment with Cannabidiol and Fluoxetine. Molecular neurobiology. 2022-12-28. PMID:36576709. |
the crosstalk between autophagy and apoptosis is one of the most important processes involved in the cell program death, and several mechanisms including oligodendrocyte apoptosis and autophagy play significant roles in activating macrophages, microglial cells, and finally demyelination in neurodegenerative disease. |
2022-12-28 |
2023-08-14 |
mouse |
| Qian Xu, Yi-Meng Zhao, Nai-Qi He, Rong Gao, Wen-Xin Xu, Xiu-Juan Zhuo, Zhong Ren, Chun-Yan Wu, Lu-Shan Li. PCSK9: A emerging participant in heart failure. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2022-12-19. PMID:36535197. |
aside from regulating lipid metabolism, pcsk9 may be involved in other biological processes such as apoptosis, autophagy, pyroptosis, inflammation, and tumor immunity and related to diabetes and neurodegenerative diseases. |
2022-12-19 |
2023-08-14 |
human |
| Chang Liu, Rong J. Manganese-induced neuronal apoptosis: new insights into the role of endoplasmic reticulum stress in regulating autophagy-related proteins. Toxicological sciences : an official journal of the Society of Toxicology. 2022-12-15. PMID:36519822. |
here, our review focuses on discussing the existing mechanisms and connections between er stress, autophagy and apoptosis, which provide a new perspective on mn-induced neuronal apoptosis, and the pathogenesis of neurodegenerative diseases. |
2022-12-15 |
2023-08-14 |
Not clear |
| Efthalia Angelopoulou, Efstratios-Stylianos Pyrgelis, Christina Piper. Emerging Potential of the Phosphodiesterase (PDE) Inhibitor Ibudilast for Neurodegenerative Diseases: An Update on Preclinical and Clinical Evidence. Molecules (Basel, Switzerland). vol 27. issue 23. 2022-12-11. PMID:36500540. |
the preclinical evidence shows that ibudilast may act neuroprotectively in neurodegenerative diseases, by suppressing neuroinflammation, inhibiting apoptosis, regulating the mitochondrial function and by affecting the ubiquitin-proteasome and autophagosome-lysosome pathways, as well as by attenuating oxidative stress. |
2022-12-11 |
2023-08-14 |
Not clear |
| Ao Li, Qun Zhao, Linxi Chen, Zhiyue L. Apelin/APJ system: an emerging therapeutic target for neurological diseases. Molecular biology reports. 2022-11-15. PMID:36378421. |
also, apelin/apj system has therapeutic effects on chronic neurodegenerative disease models, involving the regulation of neurotrophic factors, neuroendocrine, oxidative stress, neuroinflammation, neuronal apoptosis, and autophagy. |
2022-11-15 |
2023-08-14 |
Not clear |
| Hamad Ghaleb Daila. Potential of Therapeutic Small Molecules in Apoptosis Regulation in the Treatment of Neurodegenerative Diseases: An Updated Review. Molecules (Basel, Switzerland). vol 27. issue 21. 2022-11-11. PMID:36364033. |
potential of therapeutic small molecules in apoptosis regulation in the treatment of neurodegenerative diseases: an updated review. |
2022-11-11 |
2023-08-14 |
Not clear |
| Frances Vivienne Armas, Amedeo D'Angiull. Neuroinflammation and Neurodegeneration of the Central Nervous System from Air Pollutants: A Scoping Review. Toxics. vol 10. issue 11. 2022-11-10. PMID:36355957. |
specifically, we focus on evidence on magnetic resonance imaging and neurodegenerative diseases, and the links between neuronal apoptosis and inflammation. |
2022-11-10 |
2023-08-14 |
Not clear |
| Baoyi Chen, Wenting Zhang, Chuyuan Lin, Lingyun Zhan. A Comprehensive Review on Beneficial Effects of Catechins on Secondary Mitochondrial Diseases. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232871. |
it can also induce apoptosis and, eventually, multi-system damage, which leads to neurodegenerative disease. |
2022-10-14 |
2023-08-14 |
Not clear |
| Ruo-Lan Li, Ling-Yu Wang, Hu-Xinyue Duan, Qing Zhang, Xiaohui Guo, Chunjie Wu, Wei Pen. Regulation of mitochondrial dysfunction induced cell apoptosis is a potential therapeutic strategy for herbal medicine to treat neurodegenerative diseases. Frontiers in pharmacology. vol 13. 2022-10-10. PMID:36210852. |
regulation of mitochondrial dysfunction induced cell apoptosis is a potential therapeutic strategy for herbal medicine to treat neurodegenerative diseases. |
2022-10-10 |
2023-08-14 |
Not clear |
| Ruo-Lan Li, Ling-Yu Wang, Hu-Xinyue Duan, Qing Zhang, Xiaohui Guo, Chunjie Wu, Wei Pen. Regulation of mitochondrial dysfunction induced cell apoptosis is a potential therapeutic strategy for herbal medicine to treat neurodegenerative diseases. Frontiers in pharmacology. vol 13. 2022-10-10. PMID:36210852. |
therefore, in this review, we will focus on the potential therapeutic agents from herbal medicines for treating neurodegenerative diseases via suppressing apoptosis through regulation of mitochondrial dysfunction, in order to provide a foundation for the development of more candidate drugs for neurodegenerative diseases from herbal medicine. |
2022-10-10 |
2023-08-14 |
Not clear |