| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C L Bethe. Colocalization of progestin receptors with serotonin in raphe neurons of macaque. Neuroendocrinology. vol 57. issue 1. 1993-05-21. PMID:8479605. |
in summary, progesterone can have a direct action on 5ht neuronal function and thereby influence those endocrine and affective systems under serotonergic control. |
1993-05-21 |
2023-08-12 |
human |
| D G Grahame-Smit. Serotonin in affective disorders. International clinical psychopharmacology. vol 6 Suppl 4. 1992-12-16. PMID:1431011. |
it is of great interest that selective and non-selective monoamine uptake blocking agents, monoamine oxidase inhibitors, lithium and ect, all affect 5-ht function, albeit slightly differently, and that they should be efficacious in various aspects of affective illness. |
1992-12-16 |
2023-08-11 |
Not clear |
| P L Delgado, L H Price, H L Miller, R M Salomon, J Licinio, J H Krystal, G R Heninger, D S Charne. Rapid serotonin depletion as a provocative challenge test for patients with major depression: relevance to antidepressant action and the neurobiology of depression. Psychopharmacology bulletin. vol 27. issue 3. 1992-03-02. PMID:1775606. |
brain 5-ht function may be intimately involved in the modulation of some affective states and in the mechanism of action of some antidepressant medications. |
1992-03-02 |
2023-08-11 |
Not clear |
| J R Cornelius, P H Soloff, J M Perel, R F Ulric. A preliminary trial of fluoxetine in refractory borderline patients. Journal of clinical psychopharmacology. vol 11. issue 2. 1991-08-01. PMID:2056138. |
borderline personality disorder is characterized by many of the symptoms associated with serotonin dysregulation, including affective lability, suicidal behaviors, and impulsive aggression. |
1991-08-01 |
2023-08-11 |
Not clear |
| J R Cornelius, P H Soloff, J M Perel, R F Ulric. A preliminary trial of fluoxetine in refractory borderline patients. Journal of clinical psychopharmacology. vol 11. issue 2. 1991-08-01. PMID:2056138. |
the recent development of selective serotonin reuptake inhibitors such as fluoxetine makes it possible to study the role of serotonin in the etiology of affective and behavioral dyscontrol in borderline personality disorder. |
1991-08-01 |
2023-08-11 |
Not clear |
| A T Veeninga, H G Westenberg, J T Weuste. Fluvoxamine in the treatment of menstrually related mood disorders. Psychopharmacology. vol 102. issue 3. 1991-01-17. PMID:2123559. |
the results of this study do not support a role for serotonin in menstrually related affective symptoms. |
1991-01-17 |
2023-08-11 |
Not clear |
| A M Mellow, B A Lawlor, T Sunderland, E A Mueller, S E Molchan, D L Murph. Effects of daily oral m-chlorophenylpiperazine in elderly depressed patients. Initial experience with a serotonin agonist. Biological psychiatry. vol 28. issue 7. 1990-12-04. PMID:2223928. |
further studies are needed to determine the characteristics of the possible antidepressant effects of m-cpp; such work may yield greater understanding of the role of serotonin in affective and other psychiatric disorders. |
1990-12-04 |
2023-08-11 |
Not clear |
| J R Cornelius, P H Soloff, J M Perel, R F Ulric. Fluoxetine trial in borderline personality disorder. Psychopharmacology bulletin. vol 26. issue 1. 1990-08-21. PMID:2371370. |
borderline personality disorder (bpd) is defined by many of the symptoms associated with serotonin dysregulation, including affective lability, suicidal behaviors, and impulsive aggression, providing an ideal clinical model for studying the treatment of these serious disorders. |
1990-08-21 |
2023-08-11 |
Not clear |
| J R Cornelius, P H Soloff, J M Perel, R F Ulric. Fluoxetine trial in borderline personality disorder. Psychopharmacology bulletin. vol 26. issue 1. 1990-08-21. PMID:2371370. |
the recent development of selective serotonin re-uptake inhibitors such as fluoxetine makes it possible to study the role of serotonin in the etiology of affective and behavioral dyscontrol in bpd. |
1990-08-21 |
2023-08-11 |
Not clear |
| G Gross, G Huber, J Klosterkötter, M L Rao, M Lin. [Status-dependent neurochemical parameters in schizophrenic and affective diseases]. Fortschritte der Neurologie-Psychiatrie. vol 58. issue 4. 1990-07-26. PMID:1972372. |
in this study we have measured the concentrations of dopamine, noradrenaline, adrenaline, 5-ht, tsh, prolactin, hgh, melatonin, cortisol, t 3, t 4 and 28 amino acids in blood samples (examined 8 times within 24 hours) from 48 schizophrenic patients, divided in 4 subgroups (each 12 cases) with severe, moderate, slight or lacking process-activity, from 20 patients with (inactive or only slight active) depressive phases of affective psychoses and from normal controls. |
1990-07-26 |
2023-08-11 |
Not clear |
| R J Wurtman, D O'Rourke, J J Wurtma. Nutrient imbalances in depressive disorders. Possible brain mechanisms. Annals of the New York Academy of Sciences. vol 575. 1990-05-18. PMID:2699207. |
moreover, since d-fenfluramine acts specifically to enhance serotonin-mediated neurotransmission, the data further suggest that serotonin is involved in both the affective and appetitive symptoms of sad. |
1990-05-18 |
2023-08-11 |
human |
| D O'Rourke, J J Wurtman, R J Wurtman, R Chebli, R Gleaso. Treatment of seasonal depression with d-fenfluramine. The Journal of clinical psychiatry. vol 50. issue 9. 1989-10-12. PMID:2670915. |
these results indicate that d-fenfluramine may be useful in treating sad and suggest that serotonin is involved in both sad's affective and appetitive symptoms. |
1989-10-12 |
2023-08-11 |
human |
| E F Coccaro, L J Siever, H M Klar, G Maurer, K Cochrane, T B Cooper, R C Mohs, K L Davi. Serotonergic studies in patients with affective and personality disorders. Correlates with suicidal and impulsive aggressive behavior. Archives of general psychiatry. vol 46. issue 7. 1989-07-27. PMID:2735812. |
to evaluate central serotonergic function in relation to these variables, prolactin responses to a single-dose challenge with fenfluramine hydrochloride (60 mg orally), a serotonin releasing/uptake-inhibiting agent, were examined in 45 male patients with clearly defined major affective (n = 25) and/or personality disorder (n = 20) and in 18 normal male control patients. |
1989-07-27 |
2023-08-11 |
Not clear |
| J T Metz, H H Holcomb, H Y Meltze. Effect of 5-hydroxytryptophan on H-reflex recovery curves in normal subjects and patients with affective disorders. Biological psychiatry. vol 23. issue 6. 1988-05-26. PMID:3128339. |
the effect of the serotonin precursor dl-5-hydroxytryptophan (5-htp) on the hoffmann reflex recovery curve (hrrc) was studied in normal subjects and patients with affective illness. |
1988-05-26 |
2023-08-11 |
human |
| W E Bunney, B Garland-Bunney, S B Pate. Biological markers in depression. Psychopathology. vol 19 Suppl 2. 1987-06-02. PMID:2437608. |
a review of the literature suggests some promising candidates as markers of affective illness including the serotonin metabolite, 5 hiaa; 3h-imipramine platelet binding; rem induction using m-1 muscarinic agonists; and melatonin. |
1987-06-02 |
2023-08-11 |
Not clear |
| O Puciłowski, A Płaźnik, W Kostowsk. Aggressive behavior inhibition by serotonin and quipazine injected into the amygdala in the rat. Behavioral and neural biology. vol 43. issue 1. 1985-06-18. PMID:4039562. |
it is concluded that stimulation of serotonin receptors within the amygdala produces inhibition of affective and muricidal behavior in isolated rats. |
1985-06-18 |
2023-08-11 |
rat |
| A Coppen, M T Abou-Saleh, K M Wood, M J Mitchel. Treatment of bipolar affective illness with zimeldine, a 5-HT uptake inhibitor. Journal of affective disorders. vol 7. issue 3-4. 1985-03-27. PMID:6241215. |
treatment of bipolar affective illness with zimeldine, a 5-ht uptake inhibitor. |
1985-03-27 |
2023-08-12 |
Not clear |
| M Asberg, L Bertilsson, B Mårtensson, G P Scalia-Tomba, P Thorén, L Träskman-Bend. CSF monoamine metabolites in melancholia. Acta psychiatrica Scandinavica. vol 69. issue 3. 1984-05-18. PMID:6201041. |
it is suggested that the reduced concentrations of 5-hiaa and hva in the melancholic patients may be due to altered serotonin and/or dopamine functions in the central nervous system, which may be connected with an increased vulnerability to certain types of affective illness. |
1984-05-18 |
2023-08-12 |
human |
| H Y Meltzer, R C Arora, J Met. Biological studies of schizoaffective disorders. Schizophrenia bulletin. vol 10. issue 1. 1984-04-06. PMID:6422546. |
thus, both affective and schizoaffective patients but not schizophrenics, manifest abnormalities such as decreased platelet serotonin (5-ht) uptake, blunted clonidine-induced increase in serum growth hormone, shortened latency of rapid eye movement (rem) sleep, and increased rem density. |
1984-04-06 |
2023-08-12 |
Not clear |
| J Korf, W van den Burg, R H van den Hoofdakke. Acid metabolites and precursor amino acids of 5-hydroxytryptamine and dopamine in affective and other psychiatric disorders. Psychiatria clinica. vol 16. issue 1. 1983-06-23. PMID:6189146. |
acid metabolites and precursor amino acids of 5-hydroxytryptamine and dopamine in affective and other psychiatric disorders. |
1983-06-23 |
2023-08-12 |
Not clear |