| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Sagalajev, H Wei, Z Chen, I Albayrak, A Koivisto, A Pertovaar. Oxidative Stress in the Amygdala Contributes to Neuropathic Pain. Neuroscience. vol 387. 2019-03-14. PMID:29274353. |
here we studied whether amygdaloid administration of antioxidants or antagonists of trpa1 that is among ion channels activated by oxidative stress attenuates nociceptive or affective pain in experimental neuropathy, and whether this effect involves amygdaloid astrocytes or descending serotonergic pathways acting on the spinal 5-ht |
2019-03-14 |
2023-08-13 |
Not clear |
| Ting Zhang, Lu Huang, Li Zhang, Minjie Tan, Mingliang Pu, Gary E Pickard, Kwok-Fai So, Chaoran Re. ON and OFF retinal ganglion cells differentially regulate serotonergic and GABAergic activity in the dorsal raphe nucleus. Scientific reports. vol 6. 2018-04-12. PMID:27181078. |
light, via the retinoraphe pathway can modify drn 5-ht neuron activity which may play a role in modulating affective behavior. |
2018-04-12 |
2023-08-13 |
Not clear |
| Erika Sawano, Hirokazu Doi, Tomoko Nagai, Satoko Ikeda, Kauyuki Shinohar. Interactive effects of 5-HTTLPR genotype and rearing environment on affective attitude towards own infant in Japanese mothers. Behavioural brain research. vol 325. issue Pt B. 2018-03-06. PMID:27816559. |
to address this gap, we investigated the effect of a mother's childhood rearing environment and a serotonin transporter gene polymorphism (5-httlpr) on affective attitude towards her infant. |
2018-03-06 |
2023-08-13 |
Not clear |
| Rodrigo Noseda, David Borsook, Rami Burstei. Neuropeptides and Neurotransmitters That Modulate Thalamo-Cortical Pathways Relevant to Migraine Headache. Headache. vol 57 Suppl 2. 2018-03-02. PMID:28485844. |
following the presentation of scientific evidence for monosynaptic connections between thalamic trigeminovascular neurons and axons containing glutamate, gaba, dopamine, noradrenaline, serotonin, histamine, orexin, and melanin-concentrating hormone, this review synthesizes a large body of data to propose that the transmission of headache-related nociceptive signals from the thalamus to the cortex is modulated by potentially opposing forces and that the so-called 'decision' of which system (neuropeptide/neurotransmitter) will dominate the firing of a trigeminovascular thalamic neuron at any given time is determined by the constantly changing physiological (sleep, wakefulness, food intake, body temperature, heart rate, blood pressure), behavioral (addiction, isolation), cognitive (attention, learning, memory use), and affective (stress, anxiety, depression, anger) adjustment needed to keep homeostasis. |
2018-03-02 |
2023-08-13 |
Not clear |
| Paula Diane Trotter, Francis McGlone, Shane McKie, Martyn McFarquhar, Rebecca Elliott, Susannah Claire Walker, John Francis William Deaki. Effects of acute tryptophan depletion on central processing of CT-targeted and discriminatory touch in humans. The European journal of neuroscience. vol 44. issue 4. 2018-02-01. PMID:27307373. |
we tested a theory that ct-activating touch engages the pro-social functions of serotonin, by determining whether reducing serotonin, through acute tryptophan depletion, diminishes subjective pleasantness and affective brain responses to gentle touch. |
2018-02-01 |
2023-08-13 |
human |
| Lenka Seillier, Corinna Lorenz, Katsuhisa Kawaguchi, Torben Ott, Andreas Nieder, Paria Pourriahi, Hendrikje Nienbor. Serotonin Decreases the Gain of Visual Responses in Awake Macaque V1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 47. 2017-12-04. PMID:29042433. |
serotonin, an important neuromodulator in the brain, is implicated in affective and cognitive functions. |
2017-12-04 |
2023-08-13 |
monkey |
| Vera Golimbet, Galina Korovaitseva, Tatyana Lezheiko, L I Abramova, V G Kaled. The serotonin transporter gene 5-HTTLPR polymorphism is associated with affective psychoses but not with schizophrenia: A large-scale study in the Russian population. Journal of affective disorders. vol 208. 2017-10-23. PMID:28029428. |
the serotonin transporter gene 5-httlpr polymorphism is associated with affective psychoses but not with schizophrenia: a large-scale study in the russian population. |
2017-10-23 |
2023-08-13 |
Not clear |
| Sabrina Castellano, Andrea Ventimiglia, Salvatore Salomone, Andrea Ventimiglia, Simona De Vivo, Maria Salvina Signorelli, Elisa Bellelli, Mario Santagati, Rita Anna Cantarella, Enrica Fazio, Eugenio Aguglia, Filippo Drago, Santo Di Nuovo, Filippo Carac. Selective Serotonin Reuptake Inhibitors and Serotonin and Noradrenaline Reuptake Inhibitors Improve Cognitive Function in Partial Responders Depressed Patients: Results from a Prospective Observational Cohort Study. CNS & neurological disorders drug targets. vol 15. issue 10. 2017-10-02. PMID:27712575. |
selective serotonin reuptake inhibitors (ssris) and serotonin and noradrenaline reuptake inhibitors (snris) show efficacy on affective symptoms, but it is unclear whether or not they improve cognitive symptoms. |
2017-10-02 |
2023-08-13 |
Not clear |
| Anand Kumar Singh, Joanna Zajdel, Elahe Mirrasekhian, Nader Almoosawi, Isabell Frisch, Anna M Klawonn, Maarit Jaarola, Michael Fritz, David Engblo. Prostaglandin-mediated inhibition of serotonin signaling controls the affective component of inflammatory pain. The Journal of clinical investigation. vol 127. issue 4. 2017-09-12. PMID:28287401. |
prostaglandin-mediated inhibition of serotonin signaling controls the affective component of inflammatory pain. |
2017-09-12 |
2023-08-13 |
mouse |
| Brenda Mc Mahon, Sofie B Andersen, Martin K Madsen, Liv V Hjordt, Ida Hageman, Henrik Dam, Claus Svarer, Sofi da Cunha-Bang, William Baaré, Jacob Madsen, Lis Hasholt, Klaus Holst, Vibe G Frokjaer, Gitte M Knudse. Seasonal difference in brain serotonin transporter binding predicts symptom severity in patients with seasonal affective disorder. Brain : a journal of neurology. vol 139. issue Pt 5. 2017-05-08. PMID:26994750. |
our findings suggest that the development of depressive symptoms in winter is associated with a failure to downregulate serotonin transporter levels appropriately during exposure to the environmental stress of winter, especially in individuals with high predisposition to affective disorders.media-1vid110.1093/brain/aww043_video_abstractaww043_video_abstract. |
2017-05-08 |
2023-08-13 |
human |
| Y Worbe, S Palminteri, G Savulich, N D Daw, E Fernandez-Egea, T W Robbins, V Voo. Valence-dependent influence of serotonin depletion on model-based choice strategy. Molecular psychiatry. vol 21. issue 5. 2017-01-10. PMID:25869808. |
overall, the major implication of this study is that serotonin differentially affects goal-directed learning as a function of affective valence. |
2017-01-10 |
2023-08-13 |
human |
| B Bortolato, M Berk, M Maes, R S McIntyre, A F Carvalh. Fibromyalgia and Bipolar Disorder: Emerging Epidemiological Associations and Shared Pathophysiology. Current molecular medicine. vol 16. issue 2. 2016-10-31. PMID:26812920. |
an over-activation of the kynurenine pathway in both illnesses drives tryptophan away from the production of serotonin and melatonin, leading to affective symptoms, circadian rhythm disturbances and abnormalities in pain processing. |
2016-10-31 |
2023-08-13 |
Not clear |
| Zhenhao Shi, Yina Ma, Bing Wu, Xinhuai Wu, Yuanye Wang, Shihui Ha. Neural correlates of reflection on actual versus ideal self-discrepancy. NeuroImage. vol 124. issue Pt A. 2016-09-07. PMID:26375210. |
we investigated neural correlates of actual/ideal self-discrepancy and their associations with the serotonin transporter promoter polymorphism (5-httlpr) that moderates human affective states during self-reflection. |
2016-09-07 |
2023-08-13 |
human |
| Antonios I Christou, Satoshi Endo, Yvonne Wallis, Hayley Bair, Maurice P Zeegers, Joseph P McCleer. Variation in serotonin transporter linked polymorphic region (5-HTTLPR) short/long genotype modulates resting frontal electroencephalography asymmetries in children. Development and psychopathology. vol 28. issue 1. 2016-08-30. PMID:25990287. |
previous studies have documented the serotonin transporter linked polymorphic region (5-httlpr) as a genetic susceptibility variant that contributes to variability in outcomes related to affective psychopathology, with the short allele associated with negative affectivity and the long allele associated with positive affectivity. |
2016-08-30 |
2023-08-13 |
Not clear |
| Stephen J Bonasera, A Katrin Schenk, Evan J Luxenberg, Xidao Wang, Allan Basbaum, Laurence H Tecot. Mice Lacking Serotonin 2C Receptors Have increased Affective Responses to Aversive Stimuli. PloS one. vol 10. issue 12. 2016-06-23. PMID:26630489. |
mice lacking serotonin 2c receptors have increased affective responses to aversive stimuli. |
2016-06-23 |
2023-08-13 |
mouse |
| Stephen J Bonasera, A Katrin Schenk, Evan J Luxenberg, Xidao Wang, Allan Basbaum, Laurence H Tecot. Mice Lacking Serotonin 2C Receptors Have increased Affective Responses to Aversive Stimuli. PloS one. vol 10. issue 12. 2016-06-23. PMID:26630489. |
we proposed that serotonin 2c receptors (5-ht2crs), which are expressed within brain regions implicated in sensory and affective responses to pain, contribute to the serotonergic modulation of pain responses. |
2016-06-23 |
2023-08-13 |
mouse |
| Santiago Sánchez-Iglesias, Virginia García-Solaesa, Belén García-Berrocal, Almudena Sanchez-Martín, Carolina Lorenzo-Romo, Tomás Martín-Pinto, Andrea Gaedigk, José Manuel González-Buitrago, María Isidoro-Garcí. Role of Pharmacogenetics in Improving the Safety of Psychiatric Care by Predicting the Potential Risks of Mania in CYP2D6 Poor Metabolizers Diagnosed With Bipolar Disorder. Medicine. vol 95. issue 6. 2016-06-23. PMID:26871771. |
no specific patterns were identified for adverse events for other disorders.we propose to utilize pharmacogenetic testing as an intervention to aid in the identification of patients who are at risk of developing affective switching in bipolar disorder treated with selective serotonin reuptake inhibitors, cyp2d6 substrates, and inhibitors. |
2016-06-23 |
2023-08-13 |
Not clear |
| Claudia Sagheddu, Sonia Aroni, Marta De Felice, Salvatore Lecca, Antonio Luchicchi, Miriam Melis, Anna Lisa Muntoni, Rosaria Romano, Enza Palazzo, Francesca Guida, Sabatino Maione, Marco Pisti. Enhanced serotonin and mesolimbic dopamine transmissions in a rat model of neuropathic pain. Neuropharmacology. vol 97. 2016-05-24. PMID:26113399. |
to assess whether these neurons display early changes in their activity that in the long-term might lead to chronicization, maladaptive plasticity and affective consequences, we carried out in vivo extracellular single unit recordings from serotonin neurons in the dorsal raphe nucleus (drn) and from dopamine neurons in ventral tegmental area (vta) in the spared nerve injury (sni) model of neuropathic pain in rats. |
2016-05-24 |
2023-08-13 |
rat |
| Markus Wöhr, Marcel M van Gaalen, Rainer K W Schwartin. Affective communication in rodents: serotonin and its modulating role in ultrasonic vocalizations. Behavioural pharmacology. vol 26. issue 6. 2016-05-05. PMID:26221830. |
affective communication in rodents: serotonin and its modulating role in ultrasonic vocalizations. |
2016-05-05 |
2023-08-13 |
mouse |
| Noah H Green, Chad R Jackson, Hideki Iwamoto, Michael C Tackenberg, Douglas G McMaho. Photoperiod programs dorsal raphe serotonergic neurons and affective behaviors. Current biology : CB. vol 25. issue 10. 2016-04-21. PMID:25959961. |
dysregulation of serotonin neurotransmission is implicated in neurobehavioral disorders, such as depression and anxiety, and alterations in the serotonergic phenotype of raphe neurons have dramatic effects on affective behaviors in rodents. |
2016-04-21 |
2023-08-13 |
mouse |