| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Young-A Lee, Yukiori Got. Neurodevelopmental disruption of cortico-striatal function caused by degeneration of habenula neurons. PloS one. vol 6. issue 4. 2011-11-28. PMID:21559387. |
the habenula plays an important role on cognitive and affective functions by regulating monoamines transmission such as the dopamine and serotonin, such that its dysfunction is thought to underlie a number of psychiatric conditions. |
2011-11-28 |
2023-08-12 |
Not clear |
| Rebecca Elliott, Roland Zahn, J F William Deakin, Ian M Anderso. Affective cognition and its disruption in mood disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 1. 2011-11-10. PMID:20571485. |
serotonin is considered to be a key neurotransmitter involved in depression, and there is a considerable body of research exploring whether serotonin may mediate disturbances of affective cognition. |
2011-11-10 |
2023-08-12 |
human |
| Roshan Cools, Kae Nakamura, Nathaniel D Da. Serotonin and dopamine: unifying affective, activational, and decision functions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 1. 2011-11-10. PMID:20736991. |
serotonin and dopamine: unifying affective, activational, and decision functions. |
2011-11-10 |
2023-08-12 |
Not clear |
| Kathryn A Cunningham, Robert G Fox, Noelle C Anastasio, Marcy J Bubar, Sonja J Stutz, F Gerard Moeller, Scott R Gilbertson, Sharon Rosenzweig-Lipso. Selective serotonin 5-HT(2C) receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues. Neuropharmacology. vol 61. issue 3. 2011-10-14. PMID:21575646. |
serotonin (5-ht) controls affective and motivational aspects of palatable food and drug reward and the 5-ht(2c) receptor (5-ht(2c)r) has emerged as a key regulator in this regard. |
2011-10-14 |
2023-08-12 |
rat |
| Karine Madsen, Mette T Haahr, Lisbeth Marner, Sune H Keller, William F Baaré, Claus Svarer, Steen G Hasselbalch, Gitte M Knudse. Age and sex effects on 5-HT(4) receptors in the human brain: a [(11)C]SB207145 PET study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 31. issue 6. 2011-08-23. PMID:21364600. |
experimental studies indicate that the 5-ht(4) receptor activation influence cognitive function, affective symptoms, and the development of alzheimer's disease (ad). |
2011-08-23 |
2023-08-12 |
human |
| Karine Madsen, Mette T Haahr, Lisbeth Marner, Sune H Keller, William F Baaré, Claus Svarer, Steen G Hasselbalch, Gitte M Knudse. Age and sex effects on 5-HT(4) receptors in the human brain: a [(11)C]SB207145 PET study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 31. issue 6. 2011-08-23. PMID:21364600. |
the lower limbic 5-ht(4) receptor binding in women supports a role for 5-ht(4) receptors in the sex-specific differences in emotional control and might contribute to the higher prevalence of affective diseases and ad in women. |
2011-08-23 |
2023-08-12 |
human |
| Neil Dawson, Linda Ferrington, Klaus-Peter Lesch, Paul A T Kell. Cerebral metabolic responses to 5-HT2A/C receptor activation in mice with genetically modified serotonin transporter (SERT) expression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 21. issue 1. 2011-07-20. PMID:21093224. |
therefore, altered 5-ht(2a/c) receptor functioning in response to hsert gene variation may contribute to its influence on affective phenotypes. |
2011-07-20 |
2023-08-12 |
mouse |
| Fredrik Lindstedt, Jonathan Berrebi, Erik Greayer, Tina B Lonsdorf, Martin Schalling, Martin Ingvar, Eva Kose. Conditioned pain modulation is associated with common polymorphisms in the serotonin transporter gene. PloS one. vol 6. issue 3. 2011-07-18. PMID:21464942. |
variation in the serotonin transporter (5-htt) gene (slc6a4) has been shown to influence a wide range of affective processes. |
2011-07-18 |
2023-08-12 |
human |
| Antonio Muñoz-Hoyos, Antonio Molina-Carballo, Maríadelcarmen Augustin-Morales, Francisco Contreras-Chova, Ana Naranjo-Gómez, Fuensanta Justicia-Martínez, José Ubero. Psychosocial dwarfism: psychopathological aspects and putative neuroendocrine markers. Psychiatry research. vol 188. issue 1. 2011-07-12. PMID:21071098. |
significantly, there was a conspicuous reduction in the levels of each of the neuroendocrine markers (melatonin, serotonin, β-endorphins and acth) in the group suffering from affective deficiency, a diminution which was even more noticeable in the group of patients presenting delayed growth. |
2011-07-12 |
2023-08-12 |
Not clear |
| J M Muller, E Morelli, M Ansorge, J A Gingric. Serotonin transporter deficient mice are vulnerable to escape deficits following inescapable shocks. Genes, brain, and behavior. vol 10. issue 2. 2011-06-15. PMID:20955517. |
modulation of serotonin transporter (5-htt) function causes changes in affective behavior, both in humans and rodents. |
2011-06-15 |
2023-08-12 |
mouse |
| Elisabeth T Landaas, Stefan Johansson, Anne Halmøy, Ketil J Oedegaard, Ole B Fasmer, Jan Haavi. No association between the serotonin transporter gene polymorphism 5-HTTLPR and cyclothymic temperament as measured by TEMPS-A. Journal of affective disorders. vol 129. issue 1-3. 2011-06-13. PMID:20880592. |
the 5-httlpr polymorphism of the serotonin transporter gene has been found to be associated with affective temperaments, particularly the cyclothymic temperament, as measured with the temperament evaluation of memphis, pisa, paris and san diego-autoquestionnaire version (temps-a). |
2011-06-13 |
2023-08-12 |
Not clear |
| Hein J F van Marle, Indira Tendolkar, Maren Urner, Robbert J Verkes, Guillén Fernández, Guido van Winge. Subchronic duloxetine administration alters the extended amygdala circuitry in healthy individuals. NeuroImage. vol 55. issue 2. 2011-06-10. PMID:21195195. |
therefore, we used functional magnetic resonance imaging in nineteen healthy volunteers to assess the effect of two weeks of administration of the combined serotonin and norepinephrine reuptake inhibitor duloxetine (60 mg) on reactivity and functional connectivity within the affective neurocircuitry in a double-blind, placebo-controlled, crossover design. |
2011-06-10 |
2023-08-12 |
human |
| Yukihiro Ohn. Therapeutic role of 5-HT1A receptors in the treatment of schizophrenia and Parkinson's disease. CNS neuroscience & therapeutics. vol 17. issue 1. 2011-05-02. PMID:21091640. |
in the treatment of patients with parkinson's disease, 5-ht(1a) agonists are expected to improve not only affective symptoms (e.g., anxiety and depression), but also the core parkinsonian symptoms as well as antiparkinsonian agents-induced side effects (e.g., l-dopa-induced dyskinesia). |
2011-05-02 |
2023-08-12 |
Not clear |
| Jennifer A Minnix, Jason D Robinson, Cho Y Lam, Brian L Carter, Jennifer E Foreman, David J Vandenbergh, Gail E Tomlinson, David W Wetter, Paul M Cinciripin. The serotonin transporter gene and startle response during nicotine deprivation. Biological psychology. vol 86. issue 1. 2011-04-20. PMID:20888887. |
affective startle probe methodology was used to examine the effects of nicotine administration and deprivation on emotional processes among individuals carrying at least one s allele versus those with the l/l genotype of the 5-hydroxytryptamine (serotonin) transporter linked polymorphic region, 5-httlpr in the promoter region of the serotonin transporter gene [solute ligand carrier family 6 member a4 (slc6a4) or sert]. |
2011-04-20 |
2023-08-12 |
human |
| Kristin Brousseau, David Arciniegas, Susie Harri. Pharmacologic management of anxiety and affective lability during recovery from Guillain-Barré syndrome: some preliminary observations. Neuropsychiatric disease and treatment. vol 1. issue 2. 2011-04-07. PMID:18568059. |
three cases in which modest doses of selective serotonin reuptake inhibitors (ssris), alone or in combination with anticonvulsants, reduced symptoms of anxiety and affective lability during acute rehabilitation of gbs are presented. |
2011-04-07 |
2023-08-12 |
Not clear |
| Xenia Gonda, Konstantinos N Fountoulakis, Zoltan Rihmer, Andras Laszik, Hagop S Akiskal, Gyorgy Bagd. How possible is the development of an operational psychometric method to assess the presence of the 5-HTTLPR s allele? Equivocal preliminary findings. Annals of general psychiatry. vol 9. 2011-03-25. PMID:20459664. |
the s allele of the 5-hydroxytryptamine transporter-linked promoter region (5-httlpr) polymorphism of the serotonin transporter gene has been found to be associated with neuroticism-related traits, affective temperaments and response to selective serotonin reuptake inhibitor (ssri) treatment. |
2011-03-25 |
2023-08-12 |
Not clear |
| Pasquale G Frisina, Joan C Borod, Nancy S Foldi, Harriet R Tenenbau. Depression in Parkinson's disease: health risks, etiology, and treatment options. Neuropsychiatric disease and treatment. vol 4. issue 1. 2011-02-22. PMID:18728814. |
overall, we conclude that neurochemical (eg, serotonin) and psychosocial factors (eg, coping style, self-esteem, and social support) contribute to the affective disturbances found in this neuropsychiatric population. |
2011-02-22 |
2023-08-12 |
Not clear |
| V E Golimbet, O S Brusov, M I Factor, G P Zlobina, T V Lezheĭko, O M Lavrushina, E A Petrova, M A Savina, V I Skvortsov. [Interaction effect of serotonin transporter gene and brain-derived neurotrophic factor on the platelet serotonin content in stroke patients]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 110. issue 4 Suppl 2. 2010-12-10. PMID:20738025. |
we also investigated the moderating effect of genetic variants on the association between platelet serotonin content and development of affective and anxiety disorders in stroke patients in the acute period of stroke. |
2010-12-10 |
2023-08-12 |
Not clear |
| V E Golimbet, O S Brusov, M I Factor, G P Zlobina, T V Lezheĭko, O M Lavrushina, E A Petrova, M A Savina, V I Skvortsov. [Interaction effect of serotonin transporter gene and brain-derived neurotrophic factor on the platelet serotonin content in stroke patients]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 110. issue 4 Suppl 2. 2010-12-10. PMID:20738025. |
no moderating effect of genetic variants on the relationship between serotonin content and affective or anxiety disorder was found. |
2010-12-10 |
2023-08-12 |
Not clear |
| Nanna H Jensen, Thomas I Cremers, Florence Sott. Therapeutic potential of 5-HT2C receptor ligands. TheScientificWorldJournal. vol 10. 2010-11-16. PMID:20852829. |
a large body of evidence supports a critical role of serotonin 2c receptors in mediating the interaction between serotonergic and dopaminergic systems, which is at the basis of their proposed involvement in the regulation of mood, affective behavior, and memory. |
2010-11-16 |
2023-08-12 |
Not clear |