| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yan Li, Aicha Abdourahman, Joseph A Tamm, Alan L Pehrson, Connie Sánchez, Maria Gulinell. Reversal of age-associated cognitive deficits is accompanied by increased plasticity-related gene expression after chronic antidepressant administration in middle-aged mice. Pharmacology, biochemistry, and behavior. vol 135. 2016-04-12. PMID:26046533. |
in middle-aged mice, we examined the effects of a selective serotonin reuptake inhibitor (fluoxetine) and a multimodal antidepressant (vortioxetine) on cognitive and affective behaviors, brain stem cell proliferation, growth factor and gene expression. |
2016-04-12 |
2023-08-13 |
mouse |
| A F Leentjens, F R Verhey, F W Vreeling, H M van Praa. The role of serotonin in Parkinsons' Disease: An integrated approach for research of motor, cognitive and affective symptoms with functional intervention studies. Acta neuropsychiatrica. vol 10. issue 4. 2016-03-14. PMID:26971892. |
the role of serotonin in parkinsons' disease: an integrated approach for research of motor, cognitive and affective symptoms with functional intervention studies. |
2016-03-14 |
2023-08-13 |
Not clear |
| A F Leentjens, F R Verhey, F W Vreeling, H M van Praa. The role of serotonin in Parkinsons' Disease: An integrated approach for research of motor, cognitive and affective symptoms with functional intervention studies. Acta neuropsychiatrica. vol 10. issue 4. 2016-03-14. PMID:26971892. |
at the same time, reduction of serotonin activity may play a role in the expression of cognitive and affective symptoms. |
2016-03-14 |
2023-08-13 |
Not clear |
| Nicholas J Jury, Betsy A McCormick, Nelson D Horseman, Stephen C Benoit, Karen A Gregerso. Enhanced responsiveness to selective serotonin reuptake inhibitors during lactation. PloS one. vol 10. issue 2. 2016-01-11. PMID:25689282. |
serotonergic mechanisms and their dysfunction are widely presumed to be involved, which has led us to investigate whether lactation induces changes in central or peripheral serotonin (5-ht) systems and related affective behaviors. |
2016-01-11 |
2023-08-13 |
mouse |
| Desmond J Oathes, Lori M Hilt, Jack B Nitschk. Affective neural responses modulated by serotonin transporter genotype in clinical anxiety and depression. PloS one. vol 10. issue 2. 2015-11-20. PMID:25675343. |
affective neural responses modulated by serotonin transporter genotype in clinical anxiety and depression. |
2015-11-20 |
2023-08-13 |
human |
| Desmond J Oathes, Lori M Hilt, Jack B Nitschk. Affective neural responses modulated by serotonin transporter genotype in clinical anxiety and depression. PloS one. vol 10. issue 2. 2015-11-20. PMID:25675343. |
serotonin transporter gene variants are known to interact with stressful life experiences to increase chances of developing affective symptoms, and these same variants have been shown to influence amygdala reactivity to affective stimuli in non-psychiatric populations. |
2015-11-20 |
2023-08-13 |
human |
| Desmond J Oathes, Lori M Hilt, Jack B Nitschk. Affective neural responses modulated by serotonin transporter genotype in clinical anxiety and depression. PloS one. vol 10. issue 2. 2015-11-20. PMID:25675343. |
these findings link the serotonin transporter gene to affective circuitry findings in anxiety and depression psychopathology and further suggest that its impact on patients may be different from effects typically observed in healthy populations. |
2015-11-20 |
2023-08-13 |
human |
| Jens H van Dalfsen, C Rob Marku. Interaction between 5-HTTLPR genotype and cognitive stress vulnerability on sleep quality: effects of sub-chronic tryptophan administration. The international journal of neuropsychopharmacology. vol 18. issue 3. 2015-10-27. PMID:25644221. |
abundant evidence suggests that allelic variation in the serotonin transporter-linked polymorphic region (5-httlpr) influences susceptibility to stress and its affective consequences due to brain serotonergic vulnerability. |
2015-10-27 |
2023-08-13 |
Not clear |
| Vincent Bombail, Wei Qing, Karen E Chapman, Megan C Holme. Prevention of 5-hydroxytryptamine2C receptor RNA editing and alternate splicing in C57BL/6 mice activates the hypothalamic-pituitary-adrenal axis and alters mood. The European journal of neuroscience. vol 40. issue 11. 2015-07-31. PMID:25257581. |
the 5-hydroxytryptamine2c (5-ht)2c receptor is widely implicated in the aetiology of affective and eating disorders as well as regulation of the hypothalamo-pituitary-adrenal axis. |
2015-07-31 |
2023-08-13 |
mouse |
| Kayoko W Miyazaki, Katsuhiko Miyazaki, Kenji F Tanaka, Akihiro Yamanaka, Aki Takahashi, Sawako Tabuchi, Kenji Doy. Optogenetic activation of dorsal raphe serotonin neurons enhances patience for future rewards. Current biology : CB. vol 24. issue 17. 2015-05-20. PMID:25155504. |
serotonin is a neuromodulator that is involved extensively in behavioral, affective, and cognitive functions in the brain. |
2015-05-20 |
2023-08-13 |
mouse |
| Qiao-Jun Zhang, Zhong-Heng Wu, Jian Liu, Tao Wang, Shuang Wang, Ling-Na Ha. The selective 5-HT(1A) receptor antagonist WAY-100635 increases neuronal activity of the basolateral nucleus of the amygdala in 6-hydroxydopamine-lesioned rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 60. issue 2. 2015-05-16. PMID:18425316. |
furthermore, way-100635 induced an increase in the mean firing rate of projection neurons in the bl in 6-ohda-lesioned rats, suggesting that 5-ht(1a) receptor is likely to play a role in generating affective symptoms in parkinson's disease. |
2015-05-16 |
2023-08-12 |
rat |
| Jessica A Hartmann, Marieke Wichers, Alex L van Bemmel, Catherine Derom, Evert Thiery, Nele Jacobs, Jim van Os, Claudia J P Simon. The serotonin transporter 5-HTTLPR polymorphism in the association between sleep quality and affect. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 7. 2015-02-12. PMID:24486182. |
serotonin (5-ht) is associated with the regulation of affective as well as sleep-related processes. |
2015-02-12 |
2023-08-12 |
Not clear |
| Paul Cumming, Per Borghamme. Molecular imaging and the neuropathologies of Parkinson's disease. Current topics in behavioral neurosciences. vol 11. 2015-01-20. PMID:22034053. |
results of post mortem and molecular imaging studies reveal parallel degenerations of cortical noradrenaline (na) and serotonin (5-ht) innervations, which may contribute to affective and cognitive changes of pd. |
2015-01-20 |
2023-08-12 |
Not clear |
| Georg S Kranz, Christina Rami-Mark, Ulrike Kaufmann, Pia Baldinger, Andreas Hahn, Anna Höflich, Markus Savli, Patrycja Stein, Wolfgang Wadsak, Markus Mitterhauser, Dietmar Winkler, Rupert Lanzenberger, Siegfried Kaspe. Effects of hormone replacement therapy on cerebral serotonin-1A receptor binding in postmenopausal women examined with [carbonyl-¹¹C]WAY-100635. Psychoneuroendocrinology. vol 45. 2015-01-12. PMID:24845171. |
although we were not able to confirm effects of gonadal hormone treatment on 5-ht₁a receptor binding, our data do not preclude associations between sex steroid levels and serotonin, the neurotransmitter implicated most strongly in the pathogenesis of affective and anxiety disorders. |
2015-01-12 |
2023-08-13 |
human |
| Q Yu, C M Teixeira, D Mahadevia, Y Huang, D Balsam, J J Mann, J A Gingrich, M S Ansorg. Dopamine and serotonin signaling during two sensitive developmental periods differentially impact adult aggressive and affective behaviors in mice. Molecular psychiatry. vol 19. issue 6. 2015-01-09. PMID:24589889. |
dopamine and serotonin signaling during two sensitive developmental periods differentially impact adult aggressive and affective behaviors in mice. |
2015-01-09 |
2023-08-12 |
mouse |
| Tahilia J Rebello, Qinghui Yu, Nathalie M Goodfellow, Martha K Caffrey Cagliostro, Anne Teissier, Emanuela Morelli, Elena Y Demireva, Alexei Chemiakine, Gorazd B Rosoklija, Andrew J Dwork, Evelyn K Lambe, Jay A Gingrich, Mark S Ansorg. Postnatal day 2 to 11 constitutes a 5-HT-sensitive period impacting adult mPFC function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 37. 2015-01-07. PMID:25209278. |
these findings suggest that increased 5-ht signaling during p2-p11 alters adult mpfc function to increase anxiety and impair fear extinction, and imply a differential role for il and pl neurons in regulating affective behaviors. |
2015-01-07 |
2023-08-13 |
mouse |
| Helle Ruff Laursen, Hartwig Roman Siebner, Tina Haren, Kristoffer Madsen, Rikke Grønlund, Oliver Hulme, Susanne Henningsso. Variation in the oxytocin receptor gene is associated with behavioral and neural correlates of empathic accuracy. Frontiers in behavioral neuroscience. vol 8. 2014-12-24. PMID:25538588. |
the neuromodulators oxytocin and serotonin have been implicated in regulating affective processes underlying empathy. |
2014-12-24 |
2023-08-13 |
human |
| Shimako Yoshitake, Eugenia Kuteeva, Tomas Hökfelt, Françoise Mennicken, Elvar Theodorsson, Masatoshi Yamaguchi, Jan Kehr, Takashi Yoshitak. Correlation between the effects of local and intracerebroventricular infusions of galanin on 5-HT release studied by microdialysis, and distribution of galanin and galanin receptors in prefrontal cortex, ventral hippocampus, amygdala, hypothalamus, and striatum of awake rats. Synapse (New York, N.Y.). vol 68. issue 5. 2014-11-07. PMID:24430888. |
the neuropeptide galanin is implicated in regulation of affective behavior, including modulation of 5-ht signaling. |
2014-11-07 |
2023-08-12 |
rat |
| Christine Norra, Johanna Feilhauer, Gerhard Andreas Wiesmüller, Hanns Jürgen Kuner. Differential effects of endogenous lithium on neurobehavioural functioning: a study on auditory evoked potentials. Psychiatry research. vol 178. issue 1. 2014-06-03. PMID:20452041. |
low environmental concentrations in drinking water are associated with mental illnesses and behavioural offences, and at therapeutic dosages it is used to treat psychiatric (especially affective) disorders, partly by facilitating serotonergic (5-ht) neurotransmission. |
2014-06-03 |
2023-08-12 |
human |
| Omar Singleton, Britta K Hölzel, Mark Vangel, Narayan Brach, James Carmody, Sara W Laza. Change in Brainstem Gray Matter Concentration Following a Mindfulness-Based Intervention is Correlated with Improvement in Psychological Well-Being. Frontiers in human neuroscience. vol 8. 2014-03-06. PMID:24600370. |
the identified brain areas include the sites of synthesis and release of the neurotransmitters, norepinephrine and serotonin, which are involved in the modulation of arousal and mood, and have been related to a variety of affective functions as well as associated clinical dysfunctions. |
2014-03-06 |
2023-08-12 |
Not clear |