| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rui Zheng, Xinxin Wu, Si Li, Xinhao Chen, Dan Yan, Jigang H. Mechanism Exploration on the Immunoregulation of Allogeneic Heart Transplantation Rejection in Rats With Exosome miRNA and Proteins From Overexpressed IDO1 BMSCs. Cell transplantation. vol 33. 2024-04-17. PMID:38629748. |
these exos reduced inflammatory cell infiltration, mitigated myocardial damage, induced cd4 t-cell apoptosis, and alleviated transplantation rejection. |
2024-04-17 |
2024-04-19 |
rat |
| Raed Sulaiman, Adam Dale, Xiaoqian Lin, Jennifer C Aske, Kris Gaster, David Starks, Luis Rojas Espaillat, Pradip De, Nandini De. Atlas of Tumor and Tumor Microenvironment Cells of Lymphovascular Space Invasion (LVSI) in High-Grade Serous Endometrial Adenocarcinoma: A Case Study. International journal of molecular sciences. vol 25. issue 6. 2024-03-28. PMID:38542414. |
the expressions of the epithelial markers (ck8, 18, and epcam), lca (leukocyte common antigen) marker (cd45), proliferation marker (ki67), apoptosis markers (cleaved parp and cleaved caspase3), immune cell markers (cd3, cd4, cd8, cd56, cd68, cd163, foxp3, pd-1, pd-l1), pro-inflammatory marker (il-12-rb2), and fibroblast/mesenchyme markers (s100a7, sma, and te-7) of the resected tissue on the ihc stains were evaluated and scored by a pathologist. |
2024-03-28 |
2024-03-30 |
Not clear |
| Adrien Corne, Florine Adolphe, Jérôme Estaquier, Sébastien Gaumer, Jean-Marc Cors. ATF4 Signaling in HIV-1 Infection: Viral Subversion of a Stress Response Transcription Factor. Biology. vol 13. issue 3. 2024-03-27. PMID:38534416. |
the role of atf4 in autophagy and apoptosis is explored as in the context of hiv-1 infection programmed cell deaths contribute to the depletion of cd4 t cells. |
2024-03-27 |
2024-03-29 |
human |
| Kevin Englebert, Anaelle Taquin, Abdulkader Azouz, Valérie Acolty, Sylvie Vande Velde, Marie Vanhollebeke, Hadrien Innes, Louis Boon, Tibor Keler, Oberdan Leo, Stanislas Goriely, Muriel Moser, Guillaume Oldenhov. The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis. Cell reports. vol 43. issue 3. 2024-02-22. PMID:38386557. |
a comparative analysis of the cd4 compartment of both strains revealed higher numbers of fat-resident memory th2 cells in the adipose tissue of cd27 knockout mice, which correlated with decreased programmed cell death protein 1-induced apoptosis. |
2024-02-22 |
2024-02-25 |
mouse |
| Inés Moret-Tatay, Pilar Nos, Marisa Iborra, Francisco Rausell, Belén Beltrá. Catalase inhibition can modulate the ability of peripheral blood T cells to undergo apoptosis in Crohn's disease. Clinical and experimental immunology. 2024-01-22. PMID:38247555. |
the results showed that cd4 t cells from cd patients are less prone to apoptosis before they can migrate to the intestinal mucosa. |
2024-01-22 |
2024-01-24 |
Not clear |
| Shan-Shan Yu, Jian-Ling D. Current views on selenoprotein S in the pathophysiological processes of diabetes-induced atherosclerosis: potential therapeutics and underlying biomarkers. Diabetology & metabolic syndrome. vol 16. issue 1. 2024-01-04. PMID:38172976. |
furthermore, selenos forestalls the apoptosis of vascular smooth muscle cells (vsmcs) and macrophages, mitigates vascular calcification, and alleviates inflammation in macrophages and cd4 |
2024-01-04 |
2024-01-06 |
human |
| Almagul Kurmanova, Gulfairuz Urazbayeva, Aigul Terlikbayeva, Damilya Salimbaeva, Ardak Ayazbeko. Diagnostic significance of blood lymphocyte activation markers in pre-eclampsia. Clinical and experimental immunology. 2023-11-03. PMID:37921073. |
in the cd4 carrier t-lymphocyte population, there was an increased expression of the cd25/cd95 activation and apoptosis markers. |
2023-11-03 |
2023-11-08 |
Not clear |
| Xiao-Yan Guo, Yun-Tian Guo, Ze-Rui Wang, Yan-Mei Jiao, Yue Hu, Li-Na Fan, Rui-Qin Cheng, Meng-Meng Qu, Chao Zhang, Jin-Wen Song, Ruo-Nan Xu, Xing Fan, Wen Xu, Ji-Yuan Zhang, Bing-Ke Bai, En-Qiang Linghu, Yao-Kai Chen, Ping Ma, Fu-Sheng Wan. Severe intestinal barrier damage in HIV-infected immunological non-responders. Heliyon. vol 9. issue 10. 2023-10-26. PMID:37876458. |
in this study, we investigated and compared the levels of intestinal gland damage and related molecules, including the tight junction protein claudin-1, apoptosis marker caspase-3, hiv dna, cd4 |
2023-10-26 |
2023-11-08 |
human |
| Hong Wang, Liangyin Wei, Dengxuan Mao, Xiaoyu Che, Xietao Ye, Yuping Liu, Yan Che. Combination of oxymatrine (Om) and astragaloside IV (As) enhances the infiltration and function of TILs in triple-negative breast cancer (TNBC). International immunopharmacology. vol 125. issue Pt A. 2023-10-22. PMID:37866315. |
in vivo, the optimal ratio of om and as (2:1) was found to increase the apoptosis rate of tumor cells in a co-culture system and enhance the infiltration of cd4 |
2023-10-22 |
2023-11-08 |
mouse |
| Chenliang Zhou, Ting Li, Muye Xia, Ziyao Wu, Xuelin Zhong, Axing Li, Huba Khamis Rashid, Chengnuo Ma, Ruijing Zhou, Heng Duan, Xuanxuan Zhang, Jie Peng, Lin L. Bcl-2 Antagonist Obatoclax Reactivates Latent HIV-1 via the NF-κB Pathway and Induces Latent Reservoir Cell Apoptosis in Latently Infected Cells. ACS infectious diseases. 2023-10-05. PMID:37796279. |
interestingly, the phosphorylation and activation of antiapoptotic bcl-2 protein induce resistance to apoptosis during hiv-1 infection and the reactivation of hiv-1 latency in central memory cd4 |
2023-10-05 |
2023-10-07 |
Not clear |
| Fengtian Zhang, Changlong Wen, Yu Peng, Zhihao Hu, Shikeng Zheng, Weiliang Chen, Lijuan We. Biomimetic lipid nanoparticles for homologous-targeting and enhanced photodynamic therapy against glioma. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2023-09-02. PMID:37659459. |
we also confirm that slnp/icg@m combined with nir irradiation could activate mitochondria mediated apoptosis pathway, and the increased proliferation of cd4 |
2023-09-02 |
2023-09-07 |
Not clear |
| Fernanda Vieira Mesquita, Vanessa Ferreira, Danilo Mesquita, Luís Eduardo Coelho Andrad. CD4 T lymphocyte subsets display heterogeneous susceptibility to apoptosis induced by serum from patients with systemic lupus erythematosus. Advances in rheumatology (London, England). vol 63. issue 1. 2023-08-16. PMID:37587510. |
cd4 t lymphocyte subsets display heterogeneous susceptibility to apoptosis induced by serum from patients with systemic lupus erythematosus. |
2023-08-16 |
2023-09-07 |
Not clear |
| Hui Liu, Xin Wang, Peng Wang, Yu Qi Wang, Yun Yun Yi, Xin L. Novel Protein C6ORF120 Promotes Apoptosis through Mitochondria-dependent Pathway in CD4 Biomedical and environmental sciences : BES. vol 36. issue 7. 2023-08-03. PMID:37533388. |
novel protein c6orf120 promotes apoptosis through mitochondria-dependent pathway in cd4 |
2023-08-03 |
2023-08-14 |
Not clear |
| Sho Umegaki, Hidekazu Shirota, Yuki Kasahara, Tomoyuki Iwasaki, Chikashi Ishiok. Distinct role of CD8 cells and CD4 cells in antitumor immunity triggered by cell apoptosis using a Herpes simplex virus thymidine kinase/ganciclovir system. Cancer science. 2023-06-16. PMID:37322820. |
distinct role of cd8 cells and cd4 cells in antitumor immunity triggered by cell apoptosis using a herpes simplex virus thymidine kinase/ganciclovir system. |
2023-06-16 |
2023-08-14 |
Not clear |
| Sho Umegaki, Hidekazu Shirota, Yuki Kasahara, Tomoyuki Iwasaki, Chikashi Ishiok. Distinct role of CD8 cells and CD4 cells in antitumor immunity triggered by cell apoptosis using a Herpes simplex virus thymidine kinase/ganciclovir system. Cancer science. 2023-06-16. PMID:37322820. |
tumor tissues were evaluated after tumor cell apoptosis and cd4 t cell depletion to elucidate this immunological mechanism. |
2023-06-16 |
2023-08-14 |
Not clear |
| Talang Wang, Ruoyu Zhao, Junhong Zhi, Ziling Liu, Aiwei Wu, Zimei Yang, Weixu Wang, Ting Ni, Lili Jing, Ming Y. Tox4 regulates transcriptional elongation and reinitiation during murine T cell development. Communications biology. vol 6. issue 1. 2023-06-07. PMID:37286708. |
here we show that tox4 conditional knockout in mice reduces thymic cellularity, partially blocks t cell development, and decreases ratio of cd8 to cd4 through decreasing proliferation and increasing apoptosis of cd8 cells. |
2023-06-07 |
2023-08-14 |
mouse |
| Dan Ma, Zewen Wu, Xingxing Zhao, Xueqing Zhu, Qi An, Yajing Wang, Jingwen Zhao, Yazhen Su, Baoqi Yang, Ke Xu, Liyun Zhan. Immunomodulatory effects of umbilical mesenchymal stem cell-derived exosomes on CD4 Inflammopharmacology. 2023-04-03. PMID:37012581. |
abnormal proliferation, apoptosis, and differentiation of cd4 |
2023-04-03 |
2023-08-14 |
Not clear |
| Anna Dubaniewic. Mycobacterial Heat Shock Proteins in Sarcoidosis and Tuberculosis. International journal of molecular sciences. vol 24. issue 6. 2023-03-29. PMID:36982159. |
in contrast to tb, monocytes in sa were resistant to mtb-hsp-induced apoptosis, and cd4 |
2023-03-29 |
2023-08-14 |
Not clear |
| Marwa Mahmoud, Miia Juntunen, Amna Adnan, Laura Kummola, Ilkka S Junttila, Minna Kelloniemi, Tuula Tyrväinen, Heini Huhtala, Abeer I Abd El Fattah, Khalda Amr, Alaa Mohamad El Erian, Mimmi Patrikoski, Susanna Miettine. Immunomodulatory Functions of Adipose Mesenchymal Stromal/Stem Cell Derived from Donors with Type 2 Diabetes and Obesity on CD4 T cells. Stem cells (Dayton, Ohio). 2023-03-22. PMID:36945068. |
cd4 t cells cultured alone or in cocultures were assessed to evaluate proliferation, activation marker surface expression, apoptosis, the regulatory t cells (tregs; cd4 + cd25 high foxp3 +) frequency, and intracellular cytokine expression using flow cytometry. |
2023-03-22 |
2023-08-14 |
Not clear |
| Qiongyu Chen, Yan Zhao, Yonghong Zhang, Jianbo Zhang, Wenshu Lu, Chih-Hao Chang, Shisong Jian. HIV associated cell death: Peptide-induced apoptosis restricts viral transmission. Frontiers in immunology. vol 14. 2023-03-13. PMID:36911666. |
flow cytometry analysis of lymphocytes from five latent hiv-infected patients, and hiv iiib-infected mt2 cells demonstrated both necrosis and apoptosis to be the major mechanisms of cell death in cd4 |
2023-03-13 |
2023-08-14 |
human |