| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li Huang, Xuedi Zhang, Junyu Fan, Xiaolei Liu, Shuhua Luo, Dianqing Cao, Youtan Liu, Zhengyuan Xia, Hanhui Zhong, Cuiping Chen, Liangqing Zhang, Zhifeng Liu, Jing Tan. EGFR promotes the apoptosis of CD4 Journal of advanced research. 2022-05-26. PMID:35618635. |
egfr promotes the apoptosis of cd4 sepsis-induced apoptosis leads to lymphopenia including the decrease of cd4 |
2022-05-26 |
2023-08-13 |
Not clear |
| Priscila C Campos, Danielle T Cunha, Luiz P Souza-Costa, Michael U Shiloh, Luis H Franc. Bag it, tag it: ubiquitin ligases and host resistance to Mycobacterium tuberculosis. Trends in microbiology. 2022-05-01. PMID:35491351. |
host resistance to mtb depends on both adaptive and innate immunity mechanisms, including development of antigen-specific cd4 and cd8 t cells, production of inflammatory cytokines, bacterial phagocytosis and destruction within phagolysosomes, host cell apoptosis, and autophagy. |
2022-05-01 |
2023-08-13 |
Not clear |
| Jiapei Yu, Hui Li, Ju Jia, Zhisheng Huang, Shuai Liu, Ying Zheng, Shengrui Mu, Xiaoyan Deng, Xiaohui Zou, Yeming Wang, Xiao Shang, Dan Cui, Lixue Huang, Xiaoxuan Feng, William J Liu, Bin Ca. Pandemic influenza A (H1N1) virus causes abortive infection of primary human T cells. Emerging microbes & infections. 2022-03-23. PMID:35317717. |
different t cell subpopulations have distinct characterizations and functions, and we reveal the high heterogeneity of susceptibility to viral infection and biological responses such as apoptosis in various cd4 |
2022-03-23 |
2023-08-13 |
human |
| Daria Vdovenko, Carolina Balbi, Dario Di Silvestre, Giulia Passignani, Yustina M Puspitasari, Martina Zarak-Crnkovic, Pierluigi Mauri, Giovanni G Camici, Thomas F Lüscher, Urs Eriksson, Giuseppe Vassall. Microvesicles released from activated CD4 European journal of clinical investigation. 2022-03-22. PMID:35316536. |
microvesicles released from activated cd4 microvesicles are vesicles shed by plasma membranes following cell activation and apoptosis. |
2022-03-22 |
2023-08-13 |
Not clear |
| Eduardo I Tognarelli, Angello Retamal-Díaz, Mónica A Farías, Luisa F Duarte, Tomás F Palomino, Francisco J Ibañez, Claudia A Riedel, Alexis M Kalergis, Susan M Bueno, Pablo A Gonzále. Pharmacological Inhibition of IRE-1 Alpha Activity in Herpes Simplex Virus Type 1 and Type 2-Infected Dendritic Cells Enhances T Cell Activation. Frontiers in immunology. vol 12. 2022-01-24. PMID:35069537. |
interestingly, the pharmacological inhibition of the endonuclease activity of ire-1α in hsv-1- and hsv-2-infected dcs significantly reduced apoptosis in these cells and enhanced their capacity to migrate to lymph nodes and activate virus-specific cd4 |
2022-01-24 |
2023-08-13 |
human |
| Svetlana Kalinichenko, Dmitriy Komkov, Dmitriy Mazuro. HIV-1 and HTLV-1 Transmission Modes: Mechanisms and Importance for Virus Spread. Viruses. vol 14. issue 1. 2022-01-22. PMID:35062355. |
hiv replication induces the apoptosis of cd4 lymphocytes, leading to the development of acquired immunodeficiency syndrome (aids). |
2022-01-22 |
2023-08-13 |
human |
| Gaurav Kumar, Jacqueline Cottalorda-Dufayard, Rodolphe Garraffo, Francine De Salvador-Guillouët, Eric Cua, Pierre-Marie Roge. Raltegravir Inclusion Decreases CD4 T-Cells Intra-Cellular Viral Load and Increases CD4 and CD28 Positive T-Cells in Selected HIV Patients. Cells. vol 11. issue 2. 2022-01-21. PMID:35053324. |
this was associated with an increase of cd4 and cd4 + cd28+ t-cells and a decrease of hla-dr expression and apoptosis of cd4 t-cells. |
2022-01-21 |
2023-08-13 |
Not clear |
| Dimitra Kerdidani, Emmanouil Aerakis, Kleio-Maria Verrou, Ilias Angelidis, Katerina Douka, Maria-Anna Maniou, Petros Stamoulis, Katerina Goudevenou, Alejandro Prados, Christos Tzaferis, Vasileios Ntafis, Ioannis Vamvakaris, Evangelos Kaniaris, Konstantinos Vachlas, Evangelos Sepsas, Anastasios Koutsopoulos, Konstantinos Potaris, Maria Tsoumakido. Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts. The Journal of experimental medicine. vol 219. issue 2. 2022-01-14. PMID:35029648. |
lung apcafs directly activated the tcrs of effector cd4 t cells and at the same time produced c1q, which acted on t cell c1qbp to rescue them from apoptosis. |
2022-01-14 |
2023-08-13 |
human |
| Svetlana Korinfskaya, Sreeja Parameswaran, Matthew T Weirauch, Artem Barsk. Runx Transcription Factors in T Cells-What Is Beyond Thymic Development? Frontiers in immunology. vol 12. 2021-11-23. PMID:34421907. |
in this review, we discuss the diversity of runx functions in mature t helper cells, such as production of cytokines and chemokines by different cd4 t cell populations; apoptosis; and immunologic memory acquisition. |
2021-11-23 |
2023-08-13 |
Not clear |
| Ehud Chorin, Orit Gal-Garber, Yael Yagel, Dan Turner, Boaz Avidor, Gideon Berke, David Hassi. Peripheral blood mononuclear cells of HIV-infected patients contain CD8 T cells that form conjugates with and kill HIV-infected autologous CD4 T cells. Immunology. vol 144. issue 3. 2021-10-21. PMID:25216453. |
apoptosis of cd4 t cells in conjugation was recorded by digitized images and was further observed and measured by facs using annexin staining. |
2021-10-21 |
2023-08-13 |
Not clear |
| Ehud Chorin, Orit Gal-Garber, Yael Yagel, Dan Turner, Boaz Avidor, Gideon Berke, David Hassi. Peripheral blood mononuclear cells of HIV-infected patients contain CD8 T cells that form conjugates with and kill HIV-infected autologous CD4 T cells. Immunology. vol 144. issue 3. 2021-10-21. PMID:25216453. |
annexin binding and cell morphology typical of apoptosis were observed in the conjugated cd4 t cells. |
2021-10-21 |
2023-08-13 |
Not clear |
| Wei Xia, Jinxue Zhao, Bin Su, Yanmei Jiao, Wenjia Weng, Ming Zhang, Xiaodan Wang, Caiping Guo, Hao Wu, Tong Zhang, Yanqing Gao, Zaicun L. Syphilitic infection impairs immunity by inducing both apoptosis and pyroptosis of CD4 Innate immunity. vol 27. issue 1. 2021-10-01. PMID:32873094. |
syphilitic infection impairs immunity by inducing both apoptosis and pyroptosis of cd4 syphilis is an important health problem worldwide; however, few studies have probed the impact of syphilitic infection on t cell turnover. |
2021-10-01 |
2023-08-13 |
Not clear |
| Wei Xia, Jinxue Zhao, Bin Su, Yanmei Jiao, Wenjia Weng, Ming Zhang, Xiaodan Wang, Caiping Guo, Hao Wu, Tong Zhang, Yanqing Gao, Zaicun L. Syphilitic infection impairs immunity by inducing both apoptosis and pyroptosis of CD4 Innate immunity. vol 27. issue 1. 2021-10-01. PMID:32873094. |
we investigated caspase-1-mediated pyroptosis and caspase-3-mediated apoptosis of cd4 |
2021-10-01 |
2023-08-13 |
Not clear |
| Tingyan He, Yanyan Huang, Ying Luo, Yu Xia, LinLin Wang, Huan Zhang, Jiayun Ling, Jun Yan. Haploinsufficiency of A20 Due to Novel Mutations in TNFAIP3. Journal of clinical immunology. vol 40. issue 5. 2021-09-16. PMID:32514655. |
immunological phenotype tests showed elevated levels of serum pro-inflammatory cytokines, reduced naïve b cells and tfh cells, an inverted cd4:cd8 ratio, and increased susceptibility to restimulation-induced cell death (ricd) and fasl-induced apoptosis in derived t cells. |
2021-09-16 |
2023-08-13 |
Not clear |
| Kazutaka Terahara, Ryutaro Iwabuchi, Rieko Iwaki, Yoshimasa Takahashi, Yasuko Tsunetsugu-Yokot. Substantial induction of non-apoptotic CD4 T-cell death during the early phase of HIV-1 infection in a humanized mouse model. Microbes and infection. vol 23. issue 1. 2021-08-30. PMID:33049386. |
for a long time, apoptosis was considered central to cell death involved in the depletion of cd4 t cells during hiv infection. |
2021-08-30 |
2023-08-13 |
mouse |
| Vijayashree Murthy, Masanori Oshi, Yoshihisa Tokumaru, Itaru Endo, Kazuaki Takab. Increased apoptosis is associated with robust immune cell infiltration and cytolytic activity in breast cancer. American journal of cancer research. vol 11. issue 7. 2021-08-07. PMID:34354867. |
high apoptosis tumors also enriched angiogenesis and high infiltration of vascular endothelial cells, pericytes and stromal cells and significantly enriched inflammation and immune response-related gene sets and high infiltration of cd8, cd4 memory, dendritic cells, m1 and m2 macrophages and significant elevation of cytolytic activity and immune checkpoint molecules, consistently in both cohorts. |
2021-08-07 |
2023-08-13 |
Not clear |
| Lilla Prenek, Tímea Litvai, Noémi Balázs, Réka Kugyelka, Ferenc Boldizsár, József Najbauer, Péter Németh, Timea Berk. Regulatory T cells are less sensitive to glucocorticoid hormone induced apoptosis than CD4 Apoptosis : an international journal on programmed cell death. vol 25. issue 9-10. 2021-07-30. PMID:32737651. |
regulatory t cells are less sensitive to glucocorticoid hormone induced apoptosis than cd4 earlier we have reported that thymic regulatory t cells (treg) are resistant to in vivo glucocorticoid hormone (gc)-induced apoptosis, while the most gc-sensitive dp thymocytes died through the activation of mitochondrial apoptotic pathway. |
2021-07-30 |
2023-08-13 |
Not clear |
| Hamed Mahdikia, Fariba Saadati, Eric Freund, Udo S Gaipl, Keivan Majidzadeh-A, Babak Shokri, Sander Bekeschu. Gas plasma irradiation of breast cancers promotes immunogenicity, tumor reduction, and an abscopal effect in vivo. Oncoimmunology. vol 10. issue 1. 2021-07-28. PMID:33457077. |
this was concomitant with an increase of apoptosis and tumor-infiltrating cd4 |
2021-07-28 |
2023-08-13 |
mouse |
| Giacomo Casella, Javad Rasouli, Alexandra Boehm, Weifeng Zhang, Dan Xiao, Larissa Lumi Watanabe Ishikawa, Rodolfo Thome, Xing Li, Daniel Hwang, Patrizia Porazzi, Sudheer Molugu, Hsin-Yao Tang, Guang-Xian Zhang, Bogoljub Ciric, Abdolmohamad Rostam. Oligodendrocyte-derived extracellular vesicles as antigen-specific therapy for autoimmune neuroinflammation in mice. Science translational medicine. vol 12. issue 568. 2021-06-23. PMID:33148622. |
the treatment was safe and restored immune tolerance by inducing immunosuppressive monocytes and apoptosis of autoreactive cd4 |
2021-06-23 |
2023-08-13 |
mouse |
| Lam Ngoc Thao Nguyen, Lam Nhat Nguyen, Juan Zhao, Madison Schank, Xindi Dang, Dechao Cao, Sushant Khanal, Bal Krishna Chand Thakuri, Zeyuan Lu, Jinyu Zhang, Zhengke Li, Zheng D Morrison, Xiao Y Wu, Mohamed El Gazzar, Shunbin Ning, Ling Wang, Jonathan P Moorman, Zhi Q Ya. Long Non-coding RNA GAS5 Regulates T Cell Functions via miR21-Mediated Signaling in People Living With HIV. Frontiers in immunology. vol 12. 2021-06-23. PMID:33776993. |
here we show that an activation-induced decline of lncrna growth arrest-specific transcript 5 (gas5) activates dna damage response (ddr), and regulates cellular functions and apoptosis in cd4 t cells derived from people living with hiv (plhiv) via upregulation of mir-21. |
2021-06-23 |
2023-08-13 |
human |