| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lam Ngoc Thao Nguyen, Lam Nhat Nguyen, Juan Zhao, Madison Schank, Xindi Dang, Dechao Cao, Sushant Khanal, Bal Krishna Chand Thakuri, Zeyuan Lu, Jinyu Zhang, Zhengke Li, Zheng D Morrison, Xiao Y Wu, Mohamed El Gazzar, Shunbin Ning, Ling Wang, Jonathan P Moorman, Zhi Q Ya. Long Non-coding RNA GAS5 Regulates T Cell Functions via miR21-Mediated Signaling in People Living With HIV. Frontiers in immunology. vol 12. 2021-06-23. PMID:33776993. |
the sustained stimulation of t cells decreased gas5, increased mir-21 and, as a result, caused dysfunction and apoptosis in cd4 t cells. |
2021-06-23 |
2023-08-13 |
human |
| Lam Ngoc Thao Nguyen, Lam Nhat Nguyen, Juan Zhao, Madison Schank, Xindi Dang, Dechao Cao, Sushant Khanal, Bal Krishna Chand Thakuri, Zeyuan Lu, Jinyu Zhang, Zhengke Li, Zheng D Morrison, Xiao Y Wu, Mohamed El Gazzar, Shunbin Ning, Ling Wang, Jonathan P Moorman, Zhi Q Ya. Long Non-coding RNA GAS5 Regulates T Cell Functions via miR21-Mediated Signaling in People Living With HIV. Frontiers in immunology. vol 12. 2021-06-23. PMID:33776993. |
our data suggest that gas5 regulates tcr-mediated activation and apoptosis in cd4 t cells during hiv infection through mir-21-mediated signaling. |
2021-06-23 |
2023-08-13 |
human |
| Y Ana, J D Rojas Marquez, L Fozzatti, R E Baigorrí, C Marin, B A Maletto, F M Cerbán, R Radi, L Piacenza, C C Stempi. An exacerbated metabolism and mitochondrial reactive oxygen species contribute to mitochondrial alterations and apoptosis in CD4 T cells during the acute phase of Trypanosoma cruzi infection. Free radical biology & medicine. vol 163. 2021-06-22. PMID:33359261. |
an exacerbated metabolism and mitochondrial reactive oxygen species contribute to mitochondrial alterations and apoptosis in cd4 t cells during the acute phase of trypanosoma cruzi infection. |
2021-06-22 |
2023-08-13 |
mouse |
| Y Ana, J D Rojas Marquez, L Fozzatti, R E Baigorrí, C Marin, B A Maletto, F M Cerbán, R Radi, L Piacenza, C C Stempi. An exacerbated metabolism and mitochondrial reactive oxygen species contribute to mitochondrial alterations and apoptosis in CD4 T cells during the acute phase of Trypanosoma cruzi infection. Free radical biology & medicine. vol 163. 2021-06-22. PMID:33359261. |
in addition, cd4 t cells with mitochondrial alteration displayed an activated phenotype, and were less functional and more prone to apoptosis. |
2021-06-22 |
2023-08-13 |
mouse |
| Y Ana, J D Rojas Marquez, L Fozzatti, R E Baigorrí, C Marin, B A Maletto, F M Cerbán, R Radi, L Piacenza, C C Stempi. An exacerbated metabolism and mitochondrial reactive oxygen species contribute to mitochondrial alterations and apoptosis in CD4 T cells during the acute phase of Trypanosoma cruzi infection. Free radical biology & medicine. vol 163. 2021-06-22. PMID:33359261. |
remarkably, the apoptosis observed in cd4 t cells with mmp depolarization was prevented by incubation with n-acetyl cysteine (nac). |
2021-06-22 |
2023-08-13 |
mouse |
| Y Ana, J D Rojas Marquez, L Fozzatti, R E Baigorrí, C Marin, B A Maletto, F M Cerbán, R Radi, L Piacenza, C C Stempi. Corrigendum to "An exacerbated metabolism and mitochondrial reactive oxygen species contribute to mitochondrial alterations and apoptosis in CD4 T cells during the acute phase of Trypanosoma cruzi infection" [Free Rad. Biol. Med. 163 (2021) 268-280]. Free radical biology & medicine. vol 166. 2021-06-21. PMID:33483208. |
corrigendum to "an exacerbated metabolism and mitochondrial reactive oxygen species contribute to mitochondrial alterations and apoptosis in cd4 t cells during the acute phase of trypanosoma cruzi infection" [free rad. |
2021-06-21 |
2023-08-13 |
Not clear |
| Renumathy Dhanasekaran, Jangho Park, Alekesey Yevtodiyenko, David I Bellovin, Stacey J Adam, Anand Rajan Kd, Meital Gabay, Hanan Fernando, Julia Arzeno, Vinodhini Arjunan, Sergei Gryanzov, Dean W Felshe. MYC ASO Impedes Tumorigenesis and Elicits Oncogene Addiction in Autochthonous Transgenic Mouse Models of HCC and RCC. Molecular therapy. Nucleic acids. vol 21. 2021-06-10. PMID:32805488. |
treatment with myc aso in vivo, but not with a control aso, decreased proliferation, induced apoptosis, increased senescence, and remodeled the tumor microenvironment by recruitment of cd4 |
2021-06-10 |
2023-08-13 |
mouse |
| Ritudhwaj Tiwari, Anurag R Mishra, Advika Gupta, Debasis Naya. Structural similarity-based prediction of host factors associated with SARS-CoV-2 infection and pathogenesis. Journal of biomolecular structure & dynamics. 2021-05-28. PMID:33506741. |
the results show that axon guidance, membrane trafficking, vesicle-mediated transport, apoptosis, clathrin-mediated endocytosis, vpu mediated degradation of cd4 t cell, and interferon-gamma signaling are key events associated in sars-cov-2 life cycle. |
2021-05-28 |
2023-08-13 |
Not clear |
| Ritudhwaj Tiwari, Anurag R Mishra, Advika Gupta, Debasis Naya. Structural similarity-based prediction of host factors associated with SARS-CoV-2 infection and pathogenesis. Journal of biomolecular structure & dynamics. 2021-05-28. PMID:33506741. |
further, degree centrality analysis reveals that irf1/9/7, tp53, and casp3, uba52, and ubc are vital proteins for ifn-γ-mediated signaling, apoptosis, and proteasomal degradation of cd4, respectively. |
2021-05-28 |
2023-08-13 |
Not clear |
| Lori Garman, Richard C Pelikan, Astrid Rasmussen, Caleb A Lareau, Kathryn A Savoy, Umesh S Deshmukh, Harini Bagavant, Albert M Levin, Salim Daouk, Wonder P Drake, Courtney G Montgomer. Single Cell Transcriptomics Implicate Novel Monocyte and T Cell Immune Dysregulation in Sarcoidosis. Frontiers in immunology. vol 11. 2021-05-12. PMID:33363531. |
cd4 naïve t cells were enriched for markers of apoptosis and th17/t |
2021-05-12 |
2023-08-13 |
Not clear |
| Jing Huo, Taibin Liu, Fenghua Li, Xinfeng Song, Xiuli Ho. MicroRNA‑21‑5p protects melanocytes via targeting STAT3 and modulating Treg/Teff balance to alleviate vitiligo. Molecular medicine reports. vol 23. issue 1. 2021-05-11. PMID:33200798. |
increased apoptosis of melanocytes was detected after co‑culture with th17‑polarized cd4+ t cells in the presence of a mir‑21‑5p mimic. |
2021-05-11 |
2023-08-13 |
Not clear |
| Su-Xian Zhao, Wen-Cong Li, Na Fu, Guang-de Zhou, Shu-Hong Liu, Li-Na Jiang, Yu-Guo Zhang, Rong-Qi Wang, Yue-Min Nan, Jing-Min Zha. Emperipolesis mediated by CD8 Journal of cellular and molecular medicine. vol 24. issue 2. 2021-05-10. PMID:31851780. |
the expressions of ck19, cd3, cd4, cd8, cd20, ki67 and apoptosis of becs were evaluated by immunohistochemistry or immunofluorescence double labelling. |
2021-05-10 |
2023-08-13 |
Not clear |
| Junke Long, Chenxuan Yang, Yawen Zheng, Patricia Loughran, Fu Guang, Yiming Li, Hong Liao, Melanie J Scott, Daolin Tang, Timothy R Billiar, Meihong Den. Notch signaling protects CD4 T cells from STING-mediated apoptosis during acute systemic inflammation. Science advances. vol 6. issue 39. 2021-04-13. PMID:32967837. |
notch signaling protects cd4 t cells from sting-mediated apoptosis during acute systemic inflammation. |
2021-04-13 |
2023-08-13 |
Not clear |
| Junke Long, Chenxuan Yang, Yawen Zheng, Patricia Loughran, Fu Guang, Yiming Li, Hong Liao, Melanie J Scott, Daolin Tang, Timothy R Billiar, Meihong Den. Notch signaling protects CD4 T cells from STING-mediated apoptosis during acute systemic inflammation. Science advances. vol 6. issue 39. 2021-04-13. PMID:32967837. |
here, using a γ-secretase inhibitor to block notch signaling, we found that notch protected cd4 t cells from sting-mediated apoptosis during endotoxemia. |
2021-04-13 |
2023-08-13 |
Not clear |
| Junke Long, Chenxuan Yang, Yawen Zheng, Patricia Loughran, Fu Guang, Yiming Li, Hong Liao, Melanie J Scott, Daolin Tang, Timothy R Billiar, Meihong Den. Notch signaling protects CD4 T cells from STING-mediated apoptosis during acute systemic inflammation. Science advances. vol 6. issue 39. 2021-04-13. PMID:32967837. |
in conclusion, our data reveal a previously unidentified role of notch in negative regulation of sting-mediated apoptosis in cd4 t cells. |
2021-04-13 |
2023-08-13 |
Not clear |
| Johanna Strobl, Ram Vinay Pandey, Thomas Krausgruber, Lisa Kleissl, Bärbel Reininger, Merima Herac, Nadine Bayer, Christoph Krall, Philipp Wohlfarth, Margit Mitterbauer, Peter Kalhs, Werner Rabitsch, Christoph Bock, Georg Hopfinger, Georg Star. Anti-Apoptotic Molecule BCL2 Is a Therapeutic Target in Steroid-Refractory Graft-Versus-Host Disease. The Journal of investigative dermatology. vol 140. issue 11. 2021-04-02. PMID:32247860. |
inhibition of bcl2 increased the cd4 to cd8 ratio in allogeneic t cells in vitro and induced apoptosis of t cells from patients with steroid-pretreated chronic gvhd ex vivo. |
2021-04-02 |
2023-08-13 |
Not clear |
| Yu Liu, Shanshan Liu, Chenhua Wu, Wenjing Huang, Bin Xu, Shuai Lian, Li Wang, Shan Yue, Nannan Chen, Zhanbo Zh. PD-1-Mediated PI3K/Akt/mTOR, Caspase 9/Caspase 3 and ERK Pathways Are Involved in Regulating the Apoptosis and Proliferation of CD4 Frontiers in immunology. vol 11. 2021-03-29. PMID:32256500. |
pd-1-mediated pi3k/akt/mtor, caspase 9/caspase 3 and erk pathways are involved in regulating the apoptosis and proliferation of cd4 acute infection of bovine viral diarrhea virus (bvdv) is associated with immune dysfunction and can cause peripheral blood lymphopenia and lymphocyte apoptosis. |
2021-03-29 |
2023-08-13 |
cattle |
| Hyunyee Yoon, Ji Hyun Sung, Moon Jung Son. Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 Cells. Biomolecules & therapeutics. vol 29. issue 2. 2021-03-04. PMID:33148870. |
the mdpp4 enzymatic activity, cytokine expression, and cell profiles, including cell counts, cell viability, dna synthesis, and apoptosis, were measured in pokeweed mitogen (pwm)-activated cd4 |
2021-03-04 |
2023-08-13 |
Not clear |
| Dmitry D Zhdanov, Anna A Plyasova, Vadim S Pokrovsky, Marina V Pokrovskaya, Svetlana S Alexandrova, Yulia A Gladilina, Nikolay N Sokolo. Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4 Biochimie. vol 174. 2021-01-14. PMID:32315661. |
inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mrna prevents apoptosis progression and prolong viability of normal human cd4 the nuclease activity of deoxyribonuclease 1 (dnase i) is regulated by alternative splicing (as) of its mrna. |
2021-01-14 |
2023-08-13 |
human |
| Ricardo Khouri, Gilvanéia Silva-Santos, Tim Dierckx, Soraya Maria Menezes, Daniele Decanine, Kristof Theys, Aline Clara Silva, Lourdes Farré, Achiléa Bittencourt, Massimo Mangino, Mario Roederer, Anne-Mieke Vandamme, Johan Van Weyenberg. A genetic IFN/STAT1/FAS axis determines CD4 T stem cell memory levels and apoptosis in healthy controls and Adult T-cell Leukemia patients. Oncoimmunology. vol 7. issue 5. 2021-01-12. PMID:29721391. |
a genetic ifn/stat1/fas axis determines cd4 t stem cell memory levels and apoptosis in healthy controls and adult t-cell leukemia patients. |
2021-01-12 |
2023-08-13 |
Not clear |