| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrea Telek, Tamás Bíró, Eniko Bodó, Balázs I Tóth, István Borbíró, George Kunos, Ralf Pau. Inhibition of human hair follicle growth by endo- and exocannabinoids. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 21. issue 13. 2007-12-03. PMID:17567570. |
namely, the endocannabinoid n-arachidonoylethanolamide (anandamide, aea) as well as the exocannabinnoid delta (9) -tetrahydrocannabinol dose-dependently inhibited hair shaft elongation and the proliferation of hair matrix keratinocytes, and induced intraepithelial apoptosis and premature hf regression (catagen). |
2007-12-03 |
2023-08-12 |
human |
| Nicholas T Woods, Hirohito Yamaguchi, Francis Y Lee, Kapil N Bhalla, Hong-Gang Wan. Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis. Cancer research. vol 67. issue 22. 2007-12-03. PMID:18006817. |
anoikis, a bax-dependent apoptosis triggered by detachment from the extracellular matrix, is often dysfunctional in metastatic cancer cells. |
2007-12-03 |
2023-08-12 |
Not clear |
| D J Scott, A T Parkes, F Ponchel, M Cummings, I Poola, V Speir. Changes in expression of steroid receptors, their downstream target genes and their associated co-regulators during the sequential acquisition of tamoxifen resistance in vitro. International journal of oncology. vol 31. issue 3. 2007-11-30. PMID:17671682. |
in addition, genes associated with cell cycle, cell adhesion and extracellular matrix, were up-regulated while those associated with apoptosis or growth factors/hormones were down-regulated. |
2007-11-30 |
2023-08-12 |
Not clear |
| Takashi Hasebe, Mitsuko Kajita, Kenta Fujimoto, Yoshio Yaoita, Atsuko Ishizuya-Ok. Expression profiles of the duplicated matrix metalloproteinase-9 genes suggest their different roles in apoptosis of larval intestinal epithelial cells during Xenopus laevis metamorphosis. Developmental dynamics : an official publication of the American Association of Anatomists. vol 236. issue 8. 2007-11-28. PMID:17654707. |
expression profiles of the duplicated matrix metalloproteinase-9 genes suggest their different roles in apoptosis of larval intestinal epithelial cells during xenopus laevis metamorphosis. |
2007-11-28 |
2023-08-12 |
xenopus_laevis |
| Eniko Bodó, Desmond J Tobin, York Kamenisch, Tamás Bíró, Mark Berneburg, Wolfgang Funk, Ralf Pau. Dissecting the impact of chemotherapy on the human hair follicle: a pragmatic in vitro assay for studying the pathogenesis and potential management of hair follicle dystrophy. The American journal of pathology. vol 171. issue 4. 2007-11-26. PMID:17823286. |
here, we show that these organ-cultured hfs respond to a key cyclophosphamide metabolite, 4-hydroperoxycyclophosphamide (4-hc), in a manner that resembles chemotherapy-induced hf dystrophy as it occurs in vivo: namely, 4-hc induced melanin clumping and melanin incontinence, down-regulated keratinocyte proliferation, massively up-regulated apoptosis of hair matrix keratinocytes, prematurely induced catagen, and up-regulated p53. |
2007-11-26 |
2023-08-12 |
human |
| Srikumar Sengupta, Johan A den Boon, I-How Chen, Michael A Newton, David B Dahl, Meng Chen, Yu-Juen Cheng, William H Westra, Chien-Jen Chen, Allan Hildesheim, Bill Sugden, Paul Ahlquis. Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinoma. Cancer research. vol 66. issue 16. 2007-11-13. PMID:16912175. |
our data clearly reflect such tumor promotion, showing that deregulation of key proteins involved in apoptosis (bcl2-related protein a1 and fas apoptotic inhibitory molecule), cell cycle checkpoints (akip, scyl1, and nin), and metastasis (matrix metalloproteinase 1) is closely correlated with the levels of ebv gene expression in npc. |
2007-11-13 |
2023-08-12 |
human |
| K Edamura, Y Nasu, M Takaishi, T Kobayashi, F Abarzua, M Sakaguchi, Y Kashiwakura, S Ebara, T Saika, M Watanabe, N-H Huh, H Kumo. Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumor growth and metastasis in an orthotopic prostate cancer model. Cancer gene therapy. vol 14. issue 9. 2007-11-13. PMID:17599093. |
these therapeutic responses were consistent with the intratumoral apoptosis induction and in vitro suppression of cell invasion/migration with reduced matrix metalloprotease-2 activity. |
2007-11-13 |
2023-08-12 |
mouse |
| Anja Sachse, Gunter Wol. Angiotensin II-induced reactive oxygen species and the kidney. Journal of the American Society of Nephrology : JASN. vol 18. issue 9. 2007-11-13. PMID:17687073. |
they are transducers of cell growth, apoptosis, and cell migration and affect expression of inflammatory and extracellular matrix genes. |
2007-11-13 |
2023-08-12 |
human |
| Sashwati Roy, Savita Khanna, Donald E Kuhn, Cameron Rink, Willis T Williams, Jay L Zweier, Chandan K Se. Transcriptome analysis of the ischemia-reperfused remodeling myocardium: temporal changes in inflammation and extracellular matrix. Physiological genomics. vol 25. issue 3. 2007-11-08. PMID:16554547. |
the candidate genes represented three major functional categories: extracellular matrix, apoptosis, and inflammation. |
2007-11-08 |
2023-08-12 |
rat |
| Kate D Sutherland, Geoffrey J Lindeman, Jane E Visvade. The molecular culprits underlying precocious mammary gland involution. Journal of mammary gland biology and neoplasia. vol 12. issue 1. 2007-11-08. PMID:17323120. |
over the past few years, significant advances have been made in understanding the signaling pathways and downstream effectors that regulate epithelial cell apoptosis in the first phase of involution, and the importance of matrix metalloproteinases and their inhibitors in both phases of involution. |
2007-11-08 |
2023-08-12 |
mouse |
| Emmanuelle Kuntz, Jürgen Borlak, Georges Riss, Claude-Pierre Aebischer, Heinrich Bachmann, Nicole Seifert, Petra Buchwald Hunziker, Dörte Sölle, Willi Hunziker, Regina Goralczyk, Karin Wert. Transcriptomics does not show adverse effects of beta-carotene in A/J mice exposed to smoke for 2 weeks. Archives of biochemistry and biophysics. vol 465. issue 2. 2007-11-08. PMID:17707332. |
lung transcriptomics analysis revealed that cs induced drug metabolism, oxidative stress, extracellular matrix (ecm) degradation, inflammation markers, and apoptosis. |
2007-11-08 |
2023-08-12 |
mouse |
| Sally M Marshal. The podocyte: a potential therapeutic target in diabetic nephropathy? Current pharmaceutical design. vol 13. issue 26. 2007-11-07. PMID:17897015. |
these changes interact to lead to increased permeability, accumulation of abnormal extracellular matrix, apoptosis, foot process detachment and podocyte loss. |
2007-11-07 |
2023-08-12 |
Not clear |
| Yoshiyuki Saito, Isao Tachibana, Yoshito Takeda, Hiroyuki Yamane, Ping He, Mayumi Suzuki, Seigo Minami, Takashi Kijima, Mitsuhiro Yoshida, Toru Kumagai, Tadashi Osaki, Ichiro Kawas. Absence of CD9 enhances adhesion-dependent morphologic differentiation, survival, and matrix metalloproteinase-2 production in small cell lung cancer cells. Cancer research. vol 66. issue 19. 2007-11-06. PMID:17018612. |
while adhering to extracellular matrix proteins in vitro and in vivo, small cell lung cancer (sclc) cells frequently show morphologic differentiation and are protected from apoptosis. |
2007-11-06 |
2023-08-12 |
Not clear |
| Kwang Seok Ahn, Gautam Sethi, Ta-Hsiang Chao, Saskia T C Neuteboom, Madan M Chaturvedi, Michael A Palladino, Anas Younes, Bharat B Aggarwa. Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-kappaB regulated gene products. Blood. vol 110. issue 7. 2007-11-06. PMID:17609425. |
here we demonstrate that salinosporamide a potentiated the apoptosis induced by tumor necrosis factor alpha (tnf), bortezomib, and thalidomide, and this correlated with down-regulation of gene products that mediate cell proliferation (cyclin d1, cyclooxygenase-2 [cox-2], and c-myc), cell survival (bcl-2, bcl-xl, cflip, traf1, iap1, iap2, and survivin), invasion (matrix metallopro-teinase-9 [mmp-9] and icam-1), and angiogenesis (vascular endothelial growth factor [vegf]). |
2007-11-06 |
2023-08-12 |
Not clear |
| Chung-Chen Su, Yu-Ping Lin, Yu-Jung Cheng, Jyun-Yuan Huang, Woei-Jer Chuang, Yan-Shen Shan, Bei-Chang Yan. Phosphatidylinositol 3-kinase/Akt activation by integrin-tumor matrix interaction suppresses Fas-mediated apoptosis in T cells. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 7. 2007-11-06. PMID:17878356. |
phosphatidylinositol 3-kinase/akt activation by integrin-tumor matrix interaction suppresses fas-mediated apoptosis in t cells. |
2007-11-06 |
2023-08-12 |
Not clear |
| Anna Alexeyevna Mourskaia, Jason Jonathan Northey, Peter Michael Siege. Targeting aberrant TGF-beta signaling in pre-clinical models of cancer. Anti-cancer agents in medicinal chemistry. vol 7. issue 5. 2007-11-02. PMID:17896911. |
the tgf-beta signaling pathway is central to the control of diverse biological processes including cellular proliferation, cell survival, apoptosis, extracellular matrix deposition/remodeling, migration, invasion and immune regulation/inflammation. |
2007-11-02 |
2023-08-12 |
Not clear |
| Christophe Le Tourneau, Sandrine Faivre, Eric Raymon. The role of integrins in colorectal cancer. Oncology (Williston Park, N.Y.). vol 21. issue 9 Suppl 3. 2007-11-01. PMID:17927027. |
integrins have direct effects in stimulating proliferation and preventing apoptosis in cancer cells and mediating proangiogenic interactions between endothelial cells and extracellular matrix. |
2007-11-01 |
2023-08-12 |
Not clear |
| Stergios J Moschos, Laura M Drogowski, Shelley L Reppert, John M Kirkwoo. Integrins and cancer. Oncology (Williston Park, N.Y.). vol 21. issue 9 Suppl 3. 2007-11-01. PMID:17927026. |
this aberrant expression is mediated through "bidirectional" receptor signaling and interaction with corresponding signals from growth factor signaling pathways, leading to inhibition of apoptosis, induction of cell proliferation, extracellular matrix remodeling, migration, and angiogenesis. |
2007-11-01 |
2023-08-12 |
Not clear |
| Imtiaz A Mawji, Craig D Simpson, Marcela Gronda, Moyo A Williams, Rose Hurren, Clare J Henderson, Alessandro Datti, Jeffrey L Wrana, Aaron D Schimme. A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis. Cancer research. vol 67. issue 17. 2007-10-30. PMID:17804746. |
malignant epithelial cells with metastatic potential resist apoptosis that normally occurs upon loss of anchorage from the extracellular matrix, a process termed "anoikis." |
2007-10-30 |
2023-08-12 |
mouse |
| Sylvie Mathieu, René Gerolami, José Luis, Sylvie Carmona, Ossarath Kol, Lydie Crescence, Stéphane Garcia, Patrick Borentain, Assou El-Battar. Introducing alpha(1,2)-linked fucose into hepatocarcinoma cells inhibits vasculogenesis and tumor growth. International journal of cancer. vol 121. issue 8. 2007-10-29. PMID:17583578. |
several parameters were examined, including cell division and proliferation, apoptosis, adhesion to extracellular matrix components and angiogenesis/vasculogenesis. |
2007-10-29 |
2023-08-12 |
mouse |