| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Yang, Fabio M V Rossi, Edward E Putnin. Ex vivo expansion of rat bone marrow mesenchymal stromal cells on microcarrier beads in spin culture. Biomaterials. vol 28. issue 20. 2007-08-13. PMID:17433434. |
we hypothesized that disruption of cell-extracellular matrix contact either during cell expansion or immediately prior to cell transplantation may impair cell viability and facilitate apoptosis. |
2007-08-13 |
2023-08-12 |
rat |
| Pål Aukrust, Arne Yndestad, Jan Kristian Damås, Thor Ueland, Erik Øie, Lars Gullesta. Potential mechanisms of benefit with thalidomide in chronic heart failure. American journal of cardiovascular drugs : drugs, devices, and other interventions. vol 7. issue 2. 2007-08-07. PMID:17503883. |
persistent inflammation, involving increased levels of inflammatory cytokines, seems to play a pathogenic role in chronic hf by influencing heart contractility, inducing matrix degradation and fibrosis, and promoting apoptosis, contributing to myocardial remodeling. |
2007-08-07 |
2023-08-12 |
human |
| Fiona J Matthews, Stuart D Cook, Mohammed A Majid, Andrew D Dick, Valerie A Smit. Changes in the balance of the tissue inhibitor of matrix metalloproteinases (TIMPs)-1 and -3 may promote keratocyte apoptosis in keratoconus. Experimental eye research. vol 84. issue 6. 2007-08-06. PMID:17449031. |
changes in the balance of the tissue inhibitor of matrix metalloproteinases (timps)-1 and -3 may promote keratocyte apoptosis in keratoconus. |
2007-08-06 |
2023-08-12 |
Not clear |
| Fiona J Matthews, Stuart D Cook, Mohammed A Majid, Andrew D Dick, Valerie A Smit. Changes in the balance of the tissue inhibitor of matrix metalloproteinases (TIMPs)-1 and -3 may promote keratocyte apoptosis in keratoconus. Experimental eye research. vol 84. issue 6. 2007-08-06. PMID:17449031. |
this could result from corneal stromal cell apoptosis or be induced or perpetuated by the activation of matrix degrading enzymes, particularly members of the matrix metalloproteinase (mmp) family. |
2007-08-06 |
2023-08-12 |
Not clear |
| M Coolman, M de Maat, W L Van Heerde, L Felida, S Schoormans, E A P Steegers, R M Bertina, C J M de Groo. Matrix metalloproteinase-9 gene -1562C/T polymorphism mitigates preeclampsia. Placenta. vol 28. issue 7. 2007-08-03. PMID:17137622. |
prerequisites for successful placentation include trophoblast invasion, degradation and remodelling of the uterine decidual extracellular matrix, and apoptosis without thrombosis. |
2007-08-03 |
2023-08-12 |
Not clear |
| Marko Jović, Naava Naslavsky, Debora Rapaport, Mia Horowitz, Steve Capla. EHD1 regulates beta1 integrin endosomal transport: effects on focal adhesions, cell spreading and migration. Journal of cell science. vol 120. issue Pt 5. 2007-07-31. PMID:17284518. |
beta1 integrins bind to the extracellular matrix and stimulate signaling pathways leading to crucial cellular functions, including proliferation, apoptosis, cell spreading and migration. |
2007-07-31 |
2023-08-12 |
mouse |
| Betty Schwartz, Oded Shoseyov, Vladislava O Melnikova, Marya McCarty, Michael Leslie, Levava Roiz, Patricia Smirnoff, Guo-Fu Hu, Dina Lev, Menashe Bar-El. ACTIBIND, a T2 RNase, competes with angiogenin and inhibits human melanoma growth, angiogenesis, and metastasis. Cancer research. vol 67. issue 11. 2007-07-26. PMID:17545605. |
thus, there was decreased expression and activity of the matrix metalloproteinase 2 in melanoma and vascular endothelial cells, decreased vascularization, and increased tumor cell apoptosis in vivo. |
2007-07-26 |
2023-08-12 |
human |
| Feng M Ho, Shing H Liu, Wan W Lin, Chiau S Lia. Opposite effects of high glucose on MMP-2 and TIMP-2 in human endothelial cells. Journal of cellular biochemistry. vol 101. issue 2. 2007-07-24. PMID:17203468. |
although high glucose can induce matrix metalloproteinases (mmps), its inhibitors and cell apoptosis, little is known about the roles of mmps in regulating cell apoptosis in response to high glucose. |
2007-07-24 |
2023-08-12 |
human |
| Christoph Daniel, Kerstin Amann, Bernd Hohenstein, Paul Bornstein, Christian Hug. Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in experimental glomerulonephritis in mice. Journal of the American Society of Nephrology : JASN. vol 18. issue 3. 2007-07-24. PMID:17287428. |
tsp2-null mice were analyzed for kidney function, renal cortical matrix expansion, influx of inflammatory cells, proliferation, and apoptosis, as well as for capillary rarefaction after induction of anti-gbm disease. |
2007-07-24 |
2023-08-12 |
mouse |
| Joachim Weil, Heribert Schunker. [Pathophysiology of chronic heart failure]. Clinical research in cardiology : official journal of the German Cardiac Society. vol 95 Suppl 4. 2007-07-17. PMID:16598604. |
these changes in gene expression are complex and involve contractile proteins, ion channels, ca(++) handling, apoptosis, cell metabolism, the extracellular matrix, signal transduction pathways and growth factors. |
2007-07-17 |
2023-08-12 |
Not clear |
| Petri T Kovane. Mast cells: multipotent local effector cells in atherothrombosis. Immunological reviews. vol 217. 2007-07-16. PMID:17498055. |
moreover, mcs may weaken the cap if they disturb local collagen turnover by inducing apoptosis of the collagen-secreting smooth muscle cells or when they promote collagen degradation by activating matrix metalloproteinases. |
2007-07-16 |
2023-08-12 |
Not clear |
| Imtiaz A Mawji, Craig D Simpson, Rose Hurren, Marcela Gronda, Moyo A Williams, Jorge Filmus, James Jonkman, Ralph S Da Costa, Brian C Wilson, Michael P Thomas, John C Reed, Gennadi V Glinsky, Aaron D Schimme. Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis resistance and distant tumor formation. Journal of the National Cancer Institute. vol 99. issue 10. 2007-07-12. PMID:17505076. |
normal epithelial cells undergo anoikis, or apoptosis on loss of anchorage to the extracellular matrix, by initiating the death receptor pathway of caspase activation. |
2007-07-12 |
2023-08-12 |
Not clear |
| Gunter Wolf, Fuad N Ziyade. Cellular and molecular mechanisms of proteinuria in diabetic nephropathy. Nephron. Physiology. vol 106. issue 2. 2007-07-10. PMID:17570945. |
tgf-beta1 causes podocyte apoptosis and an increase in extracellular matrix deposition. |
2007-07-10 |
2023-08-12 |
Not clear |
| Pål Aukrust, Arne Yndestad, Camilla Smith, Wiggo J Sandberg, Thor Ueland, Torgun Waehre, Bente Halvorsen, Lars Gullestad, Jan Kristian Damå. Potential role for immunomodulatory therapy in atherosclerotic plaque stabilisation. Expert opinion on pharmacotherapy. vol 6. issue 13. 2007-07-05. PMID:16218879. |
thus, inflammatory cytokines may attenuate interstitial collagen synthesis, increase matrix degradation and promote apoptosis in several atheroma-associated cell types, and all these cellular events may enhance plaque vulnerability. |
2007-07-05 |
2023-08-12 |
Not clear |
| Raed N Samara, Luciana M Laguinge, J Milburn Jessu. Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with TRAIL-R2 (DR5) signaling. Cancer research. vol 67. issue 10. 2007-07-03. PMID:17510406. |
carcinoembryonic antigen (cea) is a tumor marker that is associated with metastasis, poor response to chemotherapy of colorectal cancer (crc), and anoikis, a form of apoptosis caused by cell detachment from matrix that is dependent on trail-r2 (dr5) and caspase-8 activation in crc. |
2007-07-03 |
2023-08-12 |
Not clear |
| Christoph-E Heyde, Sven K Tschoeke, Markus Hellmuth, Arwed Hostmann, Wolfgang Ertel, Andreas Oberholze. Trauma induces apoptosis in human thoracolumbar intervertebral discs. BMC clinical pathology. vol 6. 2007-07-02. PMID:16719914. |
in this regard, apoptosis of ivd cells has been suggested to be involved in the critical changes of the extracellular matrix. |
2007-07-02 |
2023-08-12 |
human |
| C M Thomas, C J Fuller, C E Whittles, M Shari. Chondrocyte death by apoptosis is associated with cartilage matrix degradation. Osteoarthritis and cartilage. vol 15. issue 1. 2007-07-02. PMID:16859932. |
chondrocyte death by apoptosis is associated with cartilage matrix degradation. |
2007-07-02 |
2023-08-12 |
Not clear |
| Chi-Chun Fong, Qi Zhang, Yue-Feng Shi, Rudolf S S Wu, Wang-Fun Fong, Mengsu Yan. Effect of hypoxia on RAW264.7 macrophages apoptosis and signaling. Toxicology. vol 235. issue 1-2. 2007-06-22. PMID:17416447. |
furthermore, gene expression profiles of raw264.7 macrophages induced by hypoxia showed that hypoxia treatment may alter expression of genes related to apoptosis, survival, cell cycle, metabolism and structural matrix. |
2007-06-22 |
2023-08-12 |
Not clear |
| Arne Yndestad, Jan Kristian Damås, Erik Øie, Thor Ueland, Lars Gullestad, Pål Aukrus. Role of inflammation in the progression of heart failure. Current cardiology reports. vol 9. issue 3. 2007-06-19. PMID:17470337. |
importantly, experimental studies have shown that inflammatory cytokines such as tumor necrosis factor-alpha, interleukin-1b, and monocyte chemoattractant peptide-1 may contribute to the development and progression of hf by promoting myocardial hypertrophy, activating matrix metalloproteinases, provoking contractile dysfunction, and inducing apoptosis. |
2007-06-19 |
2023-08-12 |
Not clear |
| Christopher J Carbone, Xavier Graña, E Premkumar Reddy, Dale S Haine. p21 loss cooperates with INK4 inactivation facilitating immortalization and Bcl-2-mediated anchorage-independent growth of oncogene-transduced primary mouse fibroblasts. Cancer research. vol 67. issue 9. 2007-06-18. PMID:17483323. |
in addition, absence of prb function renders h-ras(v12) + c-myc-transduced fibroblasts prone to apoptosis when deprived of the extracellular matrix, and oncogene-induced anchorage-independent growth of pocket protein-deficient cells requires apoptotic suppression. |
2007-06-18 |
2023-08-12 |
mouse |