| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Li, R Fridman, H R Ki. Tissue inhibitor of metalloproteinase-1 inhibits apoptosis of human breast epithelial cells. Cancer research. vol 59. issue 24. 2000-01-24. PMID:10626822. |
consistently, the matrix metalloproteinases (mmps) or their inhibitors (timps) have been suggested to regulate apoptosis. |
2000-01-24 |
2023-08-12 |
human |
| M Vitale, T Di Matola, M Bifulco, A Casamassima, G Fenzi, G Ross. Apoptosis induced by denied adhesion to extracellular matrix (anoikis) in thyroid epithelial cells is p53 dependent but fails to correlate with modulation of p53 expression. FEBS letters. vol 462. issue 1-2. 2000-01-13. PMID:10580091. |
apoptosis induced by denied adhesion to extracellular matrix (anoikis) in thyroid epithelial cells is p53 dependent but fails to correlate with modulation of p53 expression. |
2000-01-13 |
2023-08-12 |
Not clear |
| J R Dynlacht, M Earles, J Henthorn, Z V Roberts, E W Howard, J D Seno, D Sparling, M D Stor. Degradation of the nuclear matrix is a common element during radiation-induced apoptosis and necrosis. Radiation research. vol 152. issue 6. 2000-01-04. PMID:10581529. |
degradation of the nuclear matrix is a common element during radiation-induced apoptosis and necrosis. |
2000-01-04 |
2023-08-12 |
human |
| J R Dynlacht, M Earles, J Henthorn, Z V Roberts, E W Howard, J D Seno, D Sparling, M D Stor. Degradation of the nuclear matrix is a common element during radiation-induced apoptosis and necrosis. Radiation research. vol 152. issue 6. 2000-01-04. PMID:10581529. |
disassembly of the nuclear lamina and degradation of the nuclear matrix protein lamin b occurred in cells undergoing radiation-induced apoptosis or necrosis. |
2000-01-04 |
2023-08-12 |
human |
| J R Dynlacht, M Earles, J Henthorn, Z V Roberts, E W Howard, J D Seno, D Sparling, M D Stor. Degradation of the nuclear matrix is a common element during radiation-induced apoptosis and necrosis. Radiation research. vol 152. issue 6. 2000-01-04. PMID:10581529. |
these data indicate that breakdown of the nuclear matrix may be a common element in radiation-induced apoptosis and necrosis, but that the mechanisms and temporal patterns of breakdown of the nuclear lamina during apoptosis are distinct from those of necrosis. |
2000-01-04 |
2023-08-12 |
human |
| Y Lu, Y Z Lin, R LaPushin, B Cuevas, X Fang, S X Yu, M A Davies, H Khan, T Furui, M Mao, R Zinner, M C Hung, P Steck, K Siminovitch, G B Mill. The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells. Oncogene. vol 18. issue 50. 2000-01-04. PMID:10597304. |
under anchorage-independent conditions, pten also induces anoikis, a form of apoptosis that occurs when cells are dissociated from the extracellular matrix, which is enhanced in conjunction with low serum culture conditions. |
2000-01-04 |
2023-08-12 |
Not clear |
| J Masumoto, S Taniguchi, K Ayukawa, H Sarvotham, T Kishino, N Niikawa, E Hidaka, T Katsuyama, T Higuchi, J Sagar. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. The Journal of biological chemistry. vol 274. issue 48. 1999-12-29. PMID:10567338. |
the cytoskeletal and/or nuclear matrix molecules responsible for morphological changes associated with apoptosis were identified using monoclonal antibodies (mabs). |
1999-12-29 |
2023-08-12 |
human |
| C Jiang, W Jiang, C Ip, H Ganther, J L. Selenium-induced inhibition of angiogenesis in mammary cancer at chemopreventive levels of intake. Molecular carcinogenesis. vol 26. issue 4. 1999-12-28. PMID:10569799. |
in cell culture, direct exposure of human umbilical vein endothelial cells to se induced cell death predominantly through apoptosis, decreased the gelatinolytic activities of matrix metalloproteinase-2, or both. |
1999-12-28 |
2023-08-12 |
human |
| L E Dike, C S Chen, M Mrksich, J Tien, G M Whitesides, D E Ingbe. Geometric control of switching between growth, apoptosis, and differentiation during angiogenesis using micropatterned substrates. In vitro cellular & developmental biology. Animal. vol 35. issue 8. 1999-12-02. PMID:10501083. |
past studies using micropatterned substrates coated with adhesive islands of extracellular matrix revealed that capillary endothelial cells can be geometrically switched between growth and apoptosis. |
1999-12-02 |
2023-08-12 |
Not clear |
| M Tamura, J Gu, H Tran, K M Yamad. PTEN gene and integrin signaling in cancer. Journal of the National Cancer Institute. vol 91. issue 21. 1999-11-30. PMID:10547389. |
thus, pten appears to be a unique tumor suppressor-with both lipid phosphatase and protein tyrosine phosphatase activities-that negatively regulates cell interactions with the extracellular matrix and that maintains cell sensitivity to apoptosis, e.g., after loss of cell contact with the extracellular matrix. |
1999-11-30 |
2023-08-12 |
human |
| A M Costa, S Peyrol, L C Pôrto, J P Comparin, J L Foyatier, A Desmoulièr. Mechanical forces induce scar remodeling. Study in non-pressure-treated versus pressure-treated hypertrophic scars. The American journal of pathology. vol 155. issue 5. 1999-11-30. PMID:10550323. |
our results show that, in hypertrophic scars, pressure therapy restores in part the extracellular matrix organization observed in normal scar and induces the disappearance of alpha-smooth muscle actin-expressing myofibroblasts, probably by apoptosis. |
1999-11-30 |
2023-08-12 |
Not clear |
| K M Edwards, C M Kam, J C Powers, J A Trapan. The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes. The Journal of biological chemistry. vol 274. issue 43. 1999-11-23. PMID:10521426. |
serine proteases (granzymes) contained within the cytoplasmic granules of cytotoxic t cells and natural killer cells play a variety of roles including the induction of target cell apoptosis, breakdown of extracellular matrix proteins and induction of cytokine secretion by bystander leukocytes. |
1999-11-23 |
2023-08-12 |
human |
| H Okuda, M Adachi, M Miyazawa, Y Hinoda, K Ima. Protein kinase Calpha promotes apoptotic cell death in gastric cancer cells depending upon loss of anchorage. Oncogene. vol 18. issue 40. 1999-11-05. PMID:10523838. |
disruption of interactions between epithelial cells and extracellular matrix proteins leads to apoptosis of the cells, a phenomenon termed anoikis. |
1999-11-05 |
2023-08-12 |
human |
| S Otte, S Barnikol-Watanabe, G Vorbrüggen, N Hilschman. NUCB1, the Drosophila melanogaster homolog of the mammalian EF-hand proteins NEFA and nucleobindin. Mechanisms of development. vol 86. issue 1-2. 1999-11-04. PMID:10446275. |
although they have been discussed to be involved in autoimmunity, apoptosis and calcium homeostasis in the golgi apparatus and bone matrix, their exact role remains unknown. |
1999-11-04 |
2023-08-12 |
drosophila_melanogaster |
| S Song, P F Lamber. Different responses of epidermal and hair follicular cells to radiation correlate with distinct patterns of p53 and p21 induction. The American journal of pathology. vol 155. issue 4. 1999-11-04. PMID:10514395. |
epidermal cells responded to radiation by undergoing growth arrest, whereas the cells in the matrix of hair follicles underwent apoptosis but not growth arrest. |
1999-11-04 |
2023-08-12 |
mouse |
| B Tang, K de Castro, H E Barnes, W T Parks, L Stewart, E P Böttinger, D Danielpour, L M Wakefiel. Loss of responsiveness to transforming growth factor beta induces malignant transformation of nontumorigenic rat prostate epithelial cells. Cancer research. vol 59. issue 19. 1999-11-04. PMID:10519393. |
high-level expression of the dnr abolished the ability of tgf-beta to inhibit cell growth, to promote cell differentiation, and to induce apoptosis, and it partially blocked the induction of extracellular matrix gene expression. |
1999-11-04 |
2023-08-12 |
mouse |
| L Cao, V Lee, M E Adams, C Kiani, Y Zhang, W Hu, B B Yan. beta-Integrin-collagen interaction reduces chondrocyte apoptosis. Matrix biology : journal of the International Society for Matrix Biology. vol 18. issue 4. 1999-11-03. PMID:10517181. |
moreover, we showed that extracellular matrix (ecm) molecules in the culture media provide vital chondrocyte-matrix interactions; when media are changed, cells are deprived of matrix molecules and undergo apoptosis. |
1999-11-03 |
2023-08-12 |
Not clear |
| L Feng, R Balakir, P Precht, W E Horto. Bcl-2 regulates chondrocyte morphology and aggrecan gene expression independent of caspase activation and full apoptosis. Journal of cellular biochemistry. vol 74. issue 4. 1999-10-12. PMID:10440927. |
chondrocytes express a unique set of matrix proteins, including the proteoglycan aggrecan, and have been widely used to study the relationship between trophic factors and apoptosis. |
1999-10-12 |
2023-08-12 |
rat |
| B Zerega, S Cermelli, P Bianco, R Cancedda, F D Cancedd. Parathyroid hormone [PTH(1-34)] and parathyroid hormone-related protein [PTHrP(1-34)] promote reversion of hypertrophic chondrocytes to a prehypertrophic proliferating phenotype and prevent terminal differentiation of osteoblast-like cells. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 14. issue 8. 1999-09-30. PMID:10457260. |
these data indicate that pth/pthrp inhibit both the mineralization of a cartilage-like matrix and apoptosis (mimicked in the suspension culture) and the production of a mineralizing bone-like matrix, characterizing further differentiation of hypertrophic chondrocytes to osteoblasts like cells (mimicked in adhesion culture). |
1999-09-30 |
2023-08-12 |
chicken |
| Y Y Fan, J Zhang, R Barhoumi, R C Burghardt, N D Turner, J R Lupton, R S Chapki. Antagonism of CD95 signaling blocks butyrate induction of apoptosis in young adult mouse colonic cells. The American journal of physiology. vol 277. issue 2. 1999-09-23. PMID:10444408. |
to delineate the proapoptotic effect of butyrate and to avoid the confounding effects of detachment from the extracellular matrix, adherent cell apoptosis was monitored as loss of plasma membrane asymmetry and dissipation of mitochondrial membrane potential (deltapsi(mt)) by laser cytometry. |
1999-09-23 |
2023-08-12 |
mouse |