| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cristiane Busnardo, Fernando H F Alves, Carlos C Crestani, América A Scopinho, Leonardo B M Resstel, Fernando M A Corre. Paraventricular nucleus of the hypothalamus glutamate neurotransmission modulates autonomic, neuroendocrine and behavioral responses to acute restraint stress in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 11. 2014-06-17. PMID:23201369. |
moreover, our findings also indicate an involvement of pvn nmda glutamate receptors in the mediation of the plasma corticosterone response as well as in the delayed emotional consequences induced by the restraint stress. |
2014-06-17 |
2023-08-12 |
rat |
| Johnatan Ceccom, Emilie Bouhsira, Hélène Halley, Stéphanie Daumas, Jean Michel Lassall. Differential needs of zinc in the CA3 area of dorsal hippocampus for the consolidation of contextual fear and spatial memories. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 7. 2014-01-16. PMID:23772088. |
using two hippocampal-dependent behavioral paradigms (water maze and contextual fear conditioning) we now report that glutamate at ca3 synapses is necessary and sufficient for the spatial learning consolidation process, whereas glutamate and zinc released by mossy fibers are both mandatory and exert cumulative effects on contextual fear consolidation, a form of learning with a strong emotional component. |
2014-01-16 |
2023-08-12 |
Not clear |
| Amber R Salomons, Saskia S Arndt, Marla Lavrijsen, Susanne Kirchhoff, Frauke Oh. Expression of CRFR1 and Glu5R mRNA in different brain areas following repeated testing in mice that differ in habituation behaviour. Behavioural brain research. vol 246. 2013-10-28. PMID:23458743. |
the metabotropic glutamate receptor 5 (mglu5r) antagonist mpep increased c-fos expression in brain areas related to cognition while it decreased c-fos expression in brain areas processing emotions in 129p3 animals. |
2013-10-28 |
2023-08-12 |
mouse |
| Alexis W Ary, Kevin D Lominac, Melissa G Wroten, Amy R Williams, Rianne R Campbell, Osnat Ben-Shahar, Georg von Jonquieres, Matthias Klugmann, Karen K Szumlinsk. Imbalances in prefrontal cortex CC-Homer1 versus CC-Homer2 expression promote cocaine preference. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 19. 2013-08-06. PMID:23658151. |
thus, this study used virus-mediated gene transfer strategies to investigate the functional relevance of an imbalance in mpfc homer1/2 expression as it relates to various measures of sensorimotor, cognitive, emotional and motivational processing, as well as accompanying alterations in extracellular glutamate in c57bl/6j mice. |
2013-08-06 |
2023-08-12 |
mouse |
| André Schmidt, Michael Kometer, Rosilla Bachmann, Erich Seifritz, Franz Vollenweide. The NMDA antagonist ketamine and the 5-HT agonist psilocybin produce dissociable effects on structural encoding of emotional face expressions. Psychopharmacology. vol 225. issue 1. 2013-06-10. PMID:22836372. |
both glutamate and serotonin (5-ht) play a key role in the pathophysiology of emotional biases. |
2013-06-10 |
2023-08-12 |
Not clear |
| Simone Grimm, Florian Schubert, Maren Jaedke, Jürgen Gallinat, Malek Bajbou. Prefrontal cortex glutamate and extraversion. Social cognitive and affective neuroscience. vol 7. issue 7. 2013-04-24. PMID:22016442. |
glutamate measurement with 1h-mrs may facilitate the understanding of biological underpinnings of personality traits and psychiatric diseases associated with dysfunctions in approach behaviour and the production of positive emotional states. |
2013-04-24 |
2023-08-12 |
human |
| Teresa Femenía, Marta Gómez-Galán, Maria Lindskog, Salvatore Magar. Dysfunctional hippocampal activity affects emotion and cognition in mood disorders. Brain research. vol 1476. 2013-03-08. PMID:22541166. |
in the second section, we will survey the contribution of the glutamate and gaba systems in the pathophysiology of mood disorders, making an effort to understand the link between emotions and cognition and how novel therapeutic approaches deal with them. |
2013-03-08 |
2023-08-12 |
Not clear |
| Jordan Marrocco, Jérôme Mairesse, Richard Teke Ngomba, Viviana Silletti, Gilles Van Camp, Hammou Bouwalerh, Maria Summa, Anna Pittaluga, Ferdinando Nicoletti, Stefania Maccari, Sara Morley-Fletche. Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 48. 2013-02-19. PMID:23197707. |
we report here that prs rats showed a selective impairment of depolarization- or kainate-stimulated glutamate and [(3)h]d-aspartate release in the ventral hippocampus, a region encoding memories related to stress and emotions. |
2013-02-19 |
2023-08-12 |
rat |
| Czeslawa Kowal, Betty Diamon. Aspects of CNS lupus: mouse models of anti-NMDA receptor antibody mediated reactivity. Methods in molecular biology (Clifton, N.J.). vol 900. 2013-01-03. PMID:22933070. |
the antibody of interest binds the n-methyl-d: -aspartate receptor (nmdar), a receptor for glutamate that is a major excitatory neurotransmitter in the brain involved in synaptic plasticity, in memory and learning, and in emotional responses.we introduce basic concepts of these models and provide protocols for the following: (1) the induction of anti-dsdna, anti-nmdar antibodies, (2) testing serum antibody titer by elisa, (3) breaching blood brain barrier (bbb) integrity with lps and epinephrine, (4) passive transfer of pathology by injecting human and mouse brain-reactive antibodies into adult mouse as well as injecting the antibody into gestating mice and transfer of antibody from dam to fetus, (5) blocking nmdar-mediated pathogenicity in vivo, (6) evacuation of blood from the brain by cardiac perfusion to preserve the brain for histology, (7) evaluating injured/apoptotic neurons in brain histology, (8) preparing membrane-enriched brain -fractions for nmdar analysis. |
2013-01-03 |
2023-08-12 |
mouse |
| Atsushi Takeda, Haruna Taman. Proposed glucocorticoid-mediated zinc signaling in the hippocampus. Metallomics : integrated biometal science. vol 4. issue 7. 2012-10-29. PMID:22610492. |
zn(2+) signal participates in cognitive and emotional behavior in cooperation with signaling of glucocorticoids and glutamate, while can disadvantageously act on the hippocampus under sever stress circumstances. |
2012-10-29 |
2023-08-12 |
Not clear |
| Roopali Yadav, Subhash C Gupta, Brandon G Hillman, Jay M Bhatt, Dustin J Stairs, Shashank M Dravi. Deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors. PloS one. vol 7. issue 3. 2012-08-02. PMID:22412961. |
deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors. |
2012-08-02 |
2023-08-12 |
mouse |
| M Häring, S Guggenhuber, B Lut. Neuronal populations mediating the effects of endocannabinoids on stress and emotionality. Neuroscience. vol 204. 2012-07-23. PMID:22233782. |
gaba, glutamate, catecholamines and monoamines), suggesting a general mechanism for tuning neuronal activity, and thereby regulating emotion and stress responses. |
2012-07-23 |
2023-08-12 |
Not clear |
| Zhenglin Gu, Wenhua Liu, Jing Wei, Zhen Ya. Regulation of N-methyl-D-aspartic acid (NMDA) receptors by metabotropic glutamate receptor 7. The Journal of biological chemistry. vol 287. issue 13. 2012-05-16. PMID:22287544. |
emerging evidence suggests that metabotropic glutamate receptors (mglurs) are potential novel targets for brain disorders associated with the dysfunction of prefrontal cortex (pfc), a region critical for cognitive and emotional processes. |
2012-05-16 |
2023-08-12 |
Not clear |
| Branislava Curčić-Blake, Marte Swart, Gert J Ter Horst, Dave R M Langers, Ido P Kema, André Alema. Variation of the gene coding for DARPP-32 (PPP1R1B) and brain connectivity during associative emotional learning. NeuroImage. vol 59. issue 2. 2012-04-17. PMID:21878394. |
associative emotional learning, which is important for the social emotional functioning of individuals and is often impaired in psychiatric illnesses, is in part mediated by dopamine and glutamate pathways in the brain. |
2012-04-17 |
2023-08-12 |
Not clear |
| Lingling Lu, Takayoshi Mamiya, Ping Lu, Kazuya Toriumi, Akihiro Mouri, Masayuki Hiramatsu, Li-Bo Zou, Toshitaka Nabeshim. Prenatal exposure to PCP produces behavioral deficits accompanied by the overexpression of GLAST in the prefrontal cortex of postpubertal mice. Behavioural brain research. vol 220. issue 1. 2011-07-15. PMID:21277907. |
taken together, prenatal exposure to pcp produced impairments of long-term memory and emotional function which are associated with abnormalities of pre-synaptic glutamate transmission in the pfc of postpubertal mice. |
2011-07-15 |
2023-08-12 |
mouse |
| Atsushi Takeda, Haruna Taman. Zinc signaling through glucocorticoid and glutamate signaling in stressful circumstances. Journal of neuroscience research. vol 88. issue 14. 2011-06-24. PMID:20568287. |
it is likely that zinc signaling participates in cognitive and emotional behavior through glucocorticoid and glutamate signaling under stressful circumstances. |
2011-06-24 |
2023-08-12 |
Not clear |
| Marc A Beckerman, Michael J Glas. Ultrastructural relationship between the AMPA-GluR2 receptor subunit and the mu-opioid receptor in the mouse central nucleus of the amygdala. Experimental neurology. vol 227. issue 1. 2011-02-04. PMID:20970421. |
activation of glur2-expressing non-calcium-permeable ampa-type glutamate receptors in the central nucleus of the amygdala (cea) may play an important role in integrating emotion and memory with goal-directed behaviors involved in opioid addiction. |
2011-02-04 |
2023-08-12 |
mouse |
| Richard M O'Connor, Beate C Finger, Peter J Flor, John F Crya. Metabotropic glutamate receptor 7: at the interface of cognition and emotion. European journal of pharmacology. vol 639. issue 1-3. 2010-11-03. PMID:20371242. |
metabotropic glutamate receptor 7: at the interface of cognition and emotion. |
2010-11-03 |
2023-08-12 |
mouse |
| Hélène N Davi. Towards a reconceptualization of striatal interactions between glutamatergic and dopaminergic neurotransmission and their contribution to the production of movements. Current neuropharmacology. vol 7. issue 2. 2010-03-05. PMID:19949572. |
in this model, dopaminergic neurotransmission is seen as a motor pacemaker responsible for the basal and primary activation of striatal output neurons and glutamate as a driver providing a multiple combination of tonic, phasic, facilitatory and inhibitory influxes resulting from the processing of environmental, emotional and mnesic stimuli. |
2010-03-05 |
2023-08-12 |
Not clear |
| M J Glass, L Vanyo, L Quimson, V M Picke. Ultrastructural relationship between N-methyl-D-aspartate-NR1 receptor subunit and mu-opioid receptor in the mouse central nucleus of the amygdala. Neuroscience. vol 163. issue 3. 2010-01-14. PMID:19607886. |
thus, postsynaptic co-modulation of central amygdala neurons may be a key cellular substrate mediating glutamate and opioid interaction on neural signaling and plasticity associated with normal and pathological emotional processes associated with addictive behaviors. |
2010-01-14 |
2023-08-12 |
mouse |