| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guo-Ying Wang, Julia van Eijk, Traute Demirakca, Markus Sack, Annegret Krause-Utz, Sylvia Cackowski, Christian Schmahl, Gabriele End. ACC GABA levels are associated with functional activation and connectivity in the fronto-striatal network during interference inhibition in patients with borderline personality disorder. NeuroImage. vol 147. 2018-03-07. PMID:27940074. |
impulsivity often develops from disturbed inhibitory control, a function mainly regulated by γ-aminobutyric acid (gaba) levels in the anterior cingulate cortex (acc) and the fronto-striatal system. |
2018-03-07 |
2023-08-13 |
Not clear |
| Hirohito M Kondo, Dávid Farkas, Susan L Denham, Tomohisa Asai, István Winkle. Auditory multistability and neurotransmitter concentrations in the human brain. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 372. issue 1714. 2017-11-30. PMID:28044020. |
the concentrations of glutamate-glutamine (glx) and γ-aminobutyric acid (gaba) in brain regions were measured by magnetic resonance spectroscopy, while personality traits and executive functions were assessed using questionnaires and response inhibition tasks. |
2017-11-30 |
2023-08-13 |
human |
| Claudia Rangel-Barajas, George V Rebe. Dysregulation of Corticostriatal Connectivity in Huntington's Disease: A Role for Dopamine Modulation. Journal of Huntington's disease. vol 5. issue 4. 2017-10-23. PMID:27983564. |
striatal outputs, in turn, release γ-amino butyric acid (gaba) and exert inhibitory control over downstream basal ganglia targets. |
2017-10-23 |
2023-08-13 |
human |
| Tomonori Takazawa, Papiya Choudhury, Chi-Kun Tong, Charles M Conway, Grégory Scherrer, Pamela D Flood, Jun Mukai, Amy B MacDermot. Inhibition Mediated by Glycinergic and GABAergic Receptors on Excitatory Neurons in Mouse Superficial Dorsal Horn Is Location-Specific but Modified by Inflammation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 9. 2017-08-18. PMID:28130358. |
because the involvement of local inhibition in the dorsal horn, specifically that mediated by the inhibitory amino acids gaba and glycine, is so important in signal processing, we investigated regional inhibitory control of excitatory interneurons under control conditions and peripheral inflammation-induced mechanical allodynia. |
2017-08-18 |
2023-08-13 |
mouse |
| Önder Albayram, Stefan Passlick, Andras Bilkei-Gorzo, Andreas Zimmer, Christian Steinhäuse. Physiological impact of CB1 receptor expression by hippocampal GABAergic interneurons. Pflugers Archiv : European journal of physiology. vol 468. issue 4. 2016-12-13. PMID:26739712. |
activation of these receptors inhibits gaba release and thereby limits inhibitory control. |
2016-12-13 |
2023-08-13 |
mouse |
| Clara Quetscher, Ali Yildiz, Shalmali Dharmadhikari, Benjamin Glaubitz, Tobias Schmidt-Wilcke, Ulrike Dydak, Christian Best. Striatal GABA-MRS predicts response inhibition performance and its cortical electrophysiological correlates. Brain structure & function. vol 220. issue 6. 2016-06-15. PMID:25156575. |
the study shows that striatal gaba levels modulate the efficacy of response inhibition processes. |
2016-06-15 |
2023-08-13 |
Not clear |
| Clara Quetscher, Ali Yildiz, Shalmali Dharmadhikari, Benjamin Glaubitz, Tobias Schmidt-Wilcke, Ulrike Dydak, Christian Best. Striatal GABA-MRS predicts response inhibition performance and its cortical electrophysiological correlates. Brain structure & function. vol 220. issue 6. 2016-06-15. PMID:25156575. |
higher striatal gaba levels were related to better response inhibition performance. |
2016-06-15 |
2023-08-13 |
Not clear |
| Clara Quetscher, Ali Yildiz, Shalmali Dharmadhikari, Benjamin Glaubitz, Tobias Schmidt-Wilcke, Ulrike Dydak, Christian Best. Striatal GABA-MRS predicts response inhibition performance and its cortical electrophysiological correlates. Brain structure & function. vol 220. issue 6. 2016-06-15. PMID:25156575. |
we show that striatal gaba modulate specific subprocesses of response inhibition related to pre-motor inhibitory processes through the modulation of neuronal synchronization processes. |
2016-06-15 |
2023-08-13 |
Not clear |
| Carolina Gutierrez Herrera, Marta Carus Cadavieco, Sonia Jego, Alexey Ponomarenko, Tatiana Korotkova, Antoine Adamantidi. Hypothalamic feedforward inhibition of thalamocortical network controls arousal and consciousness. Nature neuroscience. vol 19. issue 2. 2016-06-03. PMID:26691833. |
we found that gaba neurons from the lateral hypothalamus (lhgaba) exert a strong inhibitory control over trn gaba neurons (trngaba). |
2016-06-03 |
2023-08-13 |
mouse |
| Knut Kirmse, Michael Kummer, Yury Kovalchuk, Otto W Witte, Olga Garaschuk, Knut Holthof. GABA depolarizes immature neurons and inhibits network activity in the neonatal neocortex in vivo. Nature communications. vol 6. 2016-04-13. PMID:26177896. |
in summary, our data provide evidence that in vivo gaba acts as a depolarizing neurotransmitter imposing an inhibitory control on network activity in the neonatal (p3-4) neocortex. |
2016-04-13 |
2023-08-13 |
mouse |
| David A Kupferschmidt, David M Lovinge. Inhibition of presynaptic calcium transients in cortical inputs to the dorsolateral striatum by metabotropic GABA(B) and mGlu2/3 receptors. The Journal of physiology. vol 593. issue 10. 2016-02-11. PMID:25781000. |
presynaptic gaba(b) and group ii metabotropic glutamate (mglu2/3) receptors exert marked inhibitory control over corticostriatal glutamate release in the dls, yet the signalling pathways through which they do so are unclear. |
2016-02-11 |
2023-08-13 |
Not clear |
| Maria J Ribeiro, Inês R Violante, Inês Bernardino, Richard A E Edden, Miguel Castelo-Branc. Abnormal relationship between GABA, neurophysiology and impulsive behavior in neurofibromatosis type 1. Cortex; a journal devoted to the study of the nervous system and behavior. vol 64. 2015-12-02. PMID:25437375. |
we applied a multimodal approach using high-density electroencephalography (eeg), to study the evoked brain responses, and magnetic resonance spectroscopy (mrs) to measure the levels of gaba and glutamate + glutamine in the medial frontal cortex, a brain region that plays a pivotal role in inhibitory control, and also in a control region, the occipital cortex. |
2015-12-02 |
2023-08-13 |
Not clear |
| Maria J Ribeiro, Inês R Violante, Inês Bernardino, Richard A E Edden, Miguel Castelo-Branc. Abnormal relationship between GABA, neurophysiology and impulsive behavior in neurofibromatosis type 1. Cortex; a journal devoted to the study of the nervous system and behavior. vol 64. 2015-12-02. PMID:25437375. |
notably, medial frontal but not occipital gaba levels correlated with general intellectual abilities (iq) in nf1, and inhibitory control in both groups. |
2015-12-02 |
2023-08-13 |
Not clear |
| Maria J Ribeiro, Inês R Violante, Inês Bernardino, Richard A E Edden, Miguel Castelo-Branc. Abnormal relationship between GABA, neurophysiology and impulsive behavior in neurofibromatosis type 1. Cortex; a journal devoted to the study of the nervous system and behavior. vol 64. 2015-12-02. PMID:25437375. |
surprisingly, the relationship between inhibitory control and medial frontal gaba was reversed in nf1: higher gaba was associated with a faster response style whereas in controls it was related to a cautious strategy. |
2015-12-02 |
2023-08-13 |
Not clear |
| Kaspar Vog. Diversity in GABAergic signaling. Advances in pharmacology (San Diego, Calif.). vol 73. 2015-08-03. PMID:25637442. |
gaba(a) receptor-mediated synaptic transmission is responsible for inhibitory control of neural function in the brain. |
2015-08-03 |
2023-08-13 |
Not clear |
| Mykhaylo G Moldavan, Charles N Alle. GABAB receptor-mediated frequency-dependent and circadian changes in synaptic plasticity modulate retinal input to the suprachiasmatic nucleus. The Journal of physiology. vol 591. issue 10. 2013-12-05. PMID:23401614. |
during light and dark phases the rht inputs to 55% and 33% of recorded neurons, respectively, were under gabab inhibitory control indicating that the tonic inhibition induced by local changes of endogenous gaba concentration contributes to the circadian variation of rht transmitter release. |
2013-12-05 |
2023-08-12 |
rat |
| Murray B Herd, Adam R Brown, Jeremy J Lambert, Delia Belell. Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 37. 2013-12-02. PMID:24027285. |
inhibitory control of thalamocortical (tc) relay neurons is partially mediated by gaba released from neurons of the thalamic reticular nucleus (nrt), acting predominantly via synaptic α1β2γ2 gaba(a) receptors (gaba(a)rs). |
2013-12-02 |
2023-08-12 |
mouse |
| Rosana L Pagano, Erich T Fonoff, Camila S Dale, Gerson Ballester, Manoel J Teixeira, Luiz R G Britt. Motor cortex stimulation inhibits thalamic sensory neurons and enhances activity of PAG neurons: possible pathways for antinociception. Pain. vol 153. issue 12. 2013-04-30. PMID:23017297. |
we have also observed a decreased zif268, δ-aminobutyric acid (gaba), and glutamic acid decarboxylase expression within the same region, suggesting an inhibition of gabaergic interneurons of the midbrain periaqueductal gray, consequently activating neurons responsible for the descending pain inhibitory control system. |
2013-04-30 |
2023-08-12 |
rat |
| T Sakakibara, S Sukigara, T Otsuki, A Takahashi, Y Kaneko, T Kaido, Y Saito, N Sato, E Nakagawa, K Sugai, M Sasaki, Y Goto, M Ito. Imbalance of interneuron distribution between neocortex and basal ganglia: consideration of epileptogenesis of focal cortical dysplasia. Journal of the neurological sciences. vol 323. issue 1-2. 2013-04-18. PMID:22989610. |
damage or loss of inhibitory γ-aminobutyric acid (gaba)-ergic interneuron is associated with impaired inhibitory control of cortical pyramidal neurons, leading to hyperexcitability and epileptogenesis. |
2013-04-18 |
2023-08-12 |
Not clear |
| Gregory L Holmes, M D Mathieu Milh, Olivier Dula. Maturation of the human brain and epilepsy. Handbook of clinical neurology. vol 107. 2012-12-18. PMID:22938967. |
the immature brain is highly excitable due to the depolarizing effects of gaba, overexpression of glutamatergic receptors, and lack of efficient inhibitory control. |
2012-12-18 |
2023-08-12 |
human |