| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Didier, M F Belin, M Aguera, M Buda, J F Pujo. Pharmacological effects of GABA on serotonin metabolism in the rat brain. Neurochemistry international. vol 7. issue 3. 2012-10-02. PMID:20492951. |
these data are in agreement with a transsynaptic inhibitory control of gaba on serotoninergic neurons. |
2012-10-02 |
2023-08-12 |
rat |
| Tadashi Saigusa, Yuri Aono, Reiko Sekino, Takuya Uchida, Koji Takada, Yoshiyuki Oi, Noriaki Koshikawa, Alexander R Cool. In vivo neurochemical evidence that newly synthesised GABA activates GABA(B), but not GABA(A), receptors on dopaminergic nerve endings in the nucleus accumbens of freely moving rats. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:21964521. |
the present study also shows that there is an allylglycine-insensitive gaba pool that release gaba exerting an inhibitory control of the accumbal dopaminergic activity, at the level of gaba(a) receptors. |
2012-07-27 |
2023-08-12 |
rat |
| Manoel Jorge Nobre, Marcus Lira Brandã. Modulation of auditory-evoked potentials recorded in the inferior colliculus by GABAergic mechanisms in the basolateral and central nuclei of the amygdala in high- and low-anxiety rats. Brain research. vol 1421. 2012-02-07. PMID:21963315. |
γ-aminobutyric acid (gaba) mechanisms exert tonic inhibitory control over the neural substrates of aversion in the midbrain tectum. |
2012-02-07 |
2023-08-12 |
rat |
| Manoel Jorge Nobre, Marcus Lira Brandã. Modulation of auditory-evoked potentials recorded in the inferior colliculus by GABAergic mechanisms in the basolateral and central nuclei of the amygdala in high- and low-anxiety rats. Brain research. vol 1421. 2012-02-07. PMID:21963315. |
gaba mechanisms in the cea appear to play a regulatory role in aversive states, and inactivation of the bla with muscimol produced pro-aversive effects, suggesting that inactivation of the bla removed the descending inhibitory control of the neural substrates of aversion in the cic exerted by the bla. |
2012-02-07 |
2023-08-12 |
rat |
| Jean-Luc Gaiarsa, Nicola Kuczewski, Christophe Porche. Contribution of metabotropic GABA(B) receptors to neuronal network construction. Pharmacology & therapeutics. vol 132. issue 2. 2012-01-03. PMID:21718720. |
since this pioneering work, gaba(b) receptors have been identified in the central nervous system (cns), where they provide an important inhibitory control of postsynaptic excitability and presynaptic transmitter release. |
2012-01-03 |
2023-08-12 |
Not clear |
| Luis Quintero, Ricardo Cardenas, Heberto Suarez-Roc. Stress-induced hyperalgesia is associated with a reduced and delayed GABA inhibitory control that enhances post-synaptic NMDA receptor activation in the spinal cord. Pain. vol 152. issue 8. 2011-11-23. PMID:21636214. |
stress-induced hyperalgesia is associated with a reduced and delayed gaba inhibitory control that enhances post-synaptic nmda receptor activation in the spinal cord. |
2011-11-23 |
2023-08-12 |
rat |
| Etienne Sibille, Harvey M Morris, Rama S Kota, David A Lewi. GABA-related transcripts in the dorsolateral prefrontal cortex in mood disorders. The international journal of neuropsychopharmacology. vol 14. issue 6. 2011-10-27. PMID:21226980. |
subgroups of gaba interneurons exert differential inhibitory control on principal pyramidal neurons and can be identified based on the non-overlapping expression of the calcium-binding proteins parvalbumin (pv) or calretinin (cr) or the neuropeptide somatostatin (sst). |
2011-10-27 |
2023-08-12 |
human |
| Lina E Enell, Neval Kapan, Jeannette A E Söderberg, Lily Kahsai, Dick R Nässe. Insulin signaling, lifespan and stress resistance are modulated by metabotropic GABA receptors on insulin producing cells in the brain of Drosophila. PloS one. vol 5. issue 12. 2011-07-05. PMID:21209905. |
our experiments suggest that the gbr is involved in inhibitory control of dilp production and release in adult flies at metabolic stress and that this receptor mediates a gaba signal from brain interneurons that may convey nutritional signals. |
2011-07-05 |
2023-08-12 |
drosophila_melanogaster |
| Scott D Lane, Joshua L Gowi. GABAergic modulation of human social interaction in a prisoner's dilemma model by acute administration of alprazolam. Behavioural pharmacology. vol 20. issue 7. 2011-02-08. PMID:19667972. |
these behavioral changes may be facilitated by changes in inhibitory control facilitated by gaba. |
2011-02-08 |
2023-08-12 |
human |
| Sergio R Ojeda, Christopher Dubay, Alejandro Lomniczi, Gabi Kaidar, Valerie Matagne, Ursula S Sandau, Gregory A Disse. Gene networks and the neuroendocrine regulation of puberty. Molecular and cellular endocrinology. vol 324. issue 1-2. 2010-10-05. PMID:20005919. |
gabaergic and opiatergic neurons provide transsynaptic inhibitory control to the system, but gaba neurons also exert direct excitatory effects on gnrh neurons. |
2010-10-05 |
2023-08-12 |
Not clear |
| P Quérée, S Peters, T Shar. Further pharmacological characterization of 5-HT(2C) receptor agonist-induced inhibition of 5-HT neuronal activity in the dorsal raphe nucleus in vivo. British journal of pharmacology. vol 158. issue 6. 2010-02-25. PMID:19845681. |
recent experiments using non-selective 5-hydroxytryptamine (5-ht)(2c) receptor agonists including way 161503 suggested that midbrain 5-ht neurones are under the inhibitory control of 5-ht(2c) receptors, acting via neighbouring gamma-aminobutyric acid (gaba) neurones. |
2010-02-25 |
2023-08-12 |
Not clear |
| Harald Hentschke, Claudia Benkwitz, Matthew I Banks, Mark G Perkins, Gregg E Homanics, Robert A Pearc. Altered GABAA,slow inhibition and network oscillations in mice lacking the GABAA receptor beta3 subunit. Journal of neurophysiology. vol 102. issue 6. 2010-02-22. PMID:19846622. |
by contrast, slow inhibitory control of gaba(a,fast)-producing interneurons was unaffected in beta(3)(-/-) mice. |
2010-02-22 |
2023-08-12 |
mouse |
| Cristiano Nazzaro, Silvia Marino, Mario Barbieri, Anna Siniscalch. Inhibition of serotonin outflow by nociceptin/orphaninFQ in dorsal raphe nucleus slices from normal and stressed rats: Role of corticotropin releasing factor. Neurochemistry international. vol 54. issue 5-6. 2009-07-28. PMID:19418633. |
these findings indicate that (i) both corticotropin releasing factor and nociceptin/orphaninfq exert an inhibitory control on dorsal raphe nucleus serotonergic neurons; (ii) the inhibition by corticotropin releasing factor involves gamma-aminobutyric acid neurons; (iii) nociceptin/ orphaninfq inhibits dorsal raphe nucleus serotonin system in a corticotropin releasing factor- and gamma-aminobutyric acid-independent manner; (iv) nociceptin/orphaninfq modulation is still operant in slices prepared from stressed rats. |
2009-07-28 |
2023-08-12 |
rat |
| K Domschke, P Zwanzge. GABAergic and endocannabinoid dysfunction in anxiety - future therapeutic targets? Current pharmaceutical design. vol 14. issue 33. 2009-02-12. PMID:19075727. |
in particular, anxiety might be a result of insufficient inhibitory control, pointing towards a major role of the gamma-amino-butyric acid (gaba) system in these disorders. |
2009-02-12 |
2023-08-12 |
Not clear |
| S P S Ghuman, D N Jones, S Prabhakar, R F Smith, H Dobso. GABA control of GnRH release from the ewe hypothalamus in vitro: sensitivity to oestradiol. Reproduction in domestic animals = Zuchthygiene. vol 43. issue 5. 2009-02-09. PMID:18312488. |
in summary, gnrh release from the hypothalamus is predominantly under gaba(a) receptor inhibitory control and this is attenuated in the presence of oestradiol. |
2009-02-09 |
2023-08-12 |
Not clear |
| Julia M Santos, Carlos E Macedo, Marcus L Brandã. Gabaergic mechanisms of hypothalamic nuclei in the expression of conditioned fear. Neurobiology of learning and memory. vol 90. issue 3. 2009-01-16. PMID:18634894. |
it is also well known that this neural substrate is under a tonic inhibitory control exerted by gaba mechanisms. |
2009-01-16 |
2023-08-12 |
rat |
| Yuri Aono, Tadashi Saigusa, Naoko Mizoguchi, Tomoyo Iwakami, Koji Takada, Nobuhito Gionhaku, Yoshiyuki Oi, Koichiro Ueda, Noriaki Koshikawa, Alexander R Cool. Role of GABAA receptors in the endomorphin-1-, but not endomorphin-2-, induced dopamine efflux in the nucleus accumbens of freely moving rats. European journal of pharmacology. vol 580. issue 1-2. 2008-05-01. PMID:18021767. |
it is suggested that (1) muscimol acts at gaba(a) receptors on gaba-ergic neurons that exert an inhibitory control of dopaminergic neurons and, accordingly, disinhibits these dopaminergic neurons, and that (2) bicuculline acts directly at gaba(a) receptors on dopaminergic neurons and, accordingly, removes the inhibitory control of these dopaminergic neurons. |
2008-05-01 |
2023-08-12 |
rat |
| Edith M Schneider Gasser, Venceslas Duveau, George A Prenosil, Jean-Marc Fritsch. Reorganization of GABAergic circuits maintains GABAA receptor-mediated transmission onto CA1 interneurons in alpha1-subunit-null mice. The European journal of neuroscience. vol 25. issue 11. 2007-08-15. PMID:17552997. |
the majority of hippocampal interneurons strongly express gaba(a) receptors containing the alpha1 subunit, suggesting that inhibitory control of interneurons is important for proper function of hippocampal circuits. |
2007-08-15 |
2023-08-12 |
mouse |
| Ignacio Valencia, Agustin Legido, Karina Yelin, Divya Khurana, Sanjeev V Kothare, Christos D Katseto. Anomalous inhibitory circuits in cortical tubers of human tuberous sclerosis complex associated with refractory epilepsy: aberrant expression of parvalbumin and calbindin-D28k in dysplastic cortex. Journal of child neurology. vol 21. issue 12. 2007-02-23. PMID:17156698. |
damage or loss of inhibitory cortical gamma-aminobutyric acid (gaba)ergic interneurons is associated with impaired inhibitory control of neocortical pyramidal cells, leading to hyperexcitability and epileptogenesis. |
2007-02-23 |
2023-08-12 |
human |
| A N M Schoffelmeer, F Hogenboom, G Wardeh, T J De Vrie. Interactions between CB1 cannabinoid and mu opioid receptors mediating inhibition of neurotransmitter release in rat nucleus accumbens core. Neuropharmacology. vol 51. issue 4. 2006-11-06. PMID:16806307. |
moreover, dose-response curves of the agonists showed that mu and cb1 receptors mediating inhibition of [3h]glutamate release display a non-additive interaction, whereas these receptors synergistically interact regarding their inhibitory control of [3h]gaba release. |
2006-11-06 |
2023-08-12 |
rat |