| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Q Ya. Focal bicuculline increases extracellular dopamine concentration in the nucleus accumbens of freely moving rats as measured by in vivo microdialysis. European journal of pharmacology. vol 385. issue 1. 2000-02-14. PMID:10594339. |
the results suggest that local application of bicuculline increases dopamine release in the nucleus accumbens via a receptor-mediated process, and are consistent with the concept that basal dopamine release in the nucleus accumbens is under tonic inhibitory control by gaba(a) receptors within this structure. |
2000-02-14 |
2023-08-12 |
rat |
| D A Lewis, J N Pierri, D W Volk, D S Melchitzky, T U Wo. Altered GABA neurotransmission and prefrontal cortical dysfunction in schizophrenia. Biological psychiatry. vol 46. issue 5. 1999-12-29. PMID:10472415. |
the chandelier class of gaba neurons, especially those located in the middle layers of the prefrontal cortex (pfc), have been hypothesized to be preferentially involved in schizophrenia because they 1) receive direct synaptic input from dopamine axons, 2) exert powerful inhibitory control over the excitatory output of layer 3 pyramidal neurons, and 3) undergo substantial developmental changes during late adolescence, the typical age of onset of schizophrenia. |
1999-12-29 |
2023-08-12 |
human |
| S Sbrenna, M Marti, M Morari, G Calo, R Guerrini, L Beani, C Bianch. L-glutamate and gamma-aminobutyric acid efflux from rat cerebrocortical synaptosomes: modulation by kappa- and mu- but not delta- and opioid receptor like-1 receptors. The Journal of pharmacology and experimental therapeutics. vol 291. issue 3. 1999-12-20. PMID:10565862. |
it is concluded that, in the rat cerebral cortex, l-glu and gaba efflux from nerve terminals is under the direct inhibitory control of kappa- and mu- (but not delta- or orl(1)) receptors. |
1999-12-20 |
2023-08-12 |
rat |
| H H Ellenberge. Distribution of bulbospinal gamma-aminobutyric acid-synthesizing neurons of the ventral respiratory group of the rat. The Journal of comparative neurology. vol 411. issue 1. 1999-10-12. PMID:10404112. |
these results suggest that the rostral ventral respiratory group and the bötzinger complex both contain heterogeneous bulbospinal neuron populations, only some of which have gamma-aminobutyric acid (gaba)-mediated inhibitory control over phrenic motoneurons. |
1999-10-12 |
2023-08-12 |
rat |
| J Zhang, J A Engel, M Ericson, L Svensso. Involvement of the medial geniculate body in prepulse inhibition of acoustic startle. Psychopharmacology. vol 141. issue 2. 1999-04-13. PMID:9952044. |
these studies suggest that the mg is involved in the modulation of prepulse inhibition and that auditory signals relayed via the mg may be subjected to inhibitory control at this level, involving gaba neurotransmission. |
1999-04-13 |
2023-08-12 |
rat |
| C Abbadie, K Skinner, I Mitrovic, A I Basbau. Neurons in the dorsal column white matter of the spinal cord: complex neuropil in an unexpected location. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 1. 1999-03-01. PMID:9874806. |
finally, injection of a gamma-aminobutyric acid type a receptor antagonist or of substance p into the cerebrospinal fluid of the rat spinal cord induced fos expression and internalization of the neurokinin-1 receptor in these neurons, respectively, indicating that the dc neurons are under tonic inhibitory control and can respond to neurotransmitters that circulate in the cerebrospinal fluid. |
1999-03-01 |
2023-08-12 |
rat |
| Linda S Sorkin, Sylvie Puig, Denise L Jone. Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists. Pain. vol 77. issue 2. 1998-12-11. PMID:9766836. |
these results point out that, while gaba and glycine are frequently co-localized in cells of the spinal dorsal horn and both appear to mediate tonic inhibitory control systems, they are not at all equivalent and are subject to different modulatory pharmacologies. |
1998-12-11 |
2023-08-12 |
human |
| K I Rusin, H C Moise. Mu-opioid and GABA(B) receptors modulate different types of Ca2+ currents in rat nodose ganglion neurons. Neuroscience. vol 85. issue 3. 1998-08-21. PMID:9639286. |
furthermore, the results do not support a role for either protein kinase c or a in the modulatory pathway(s) coupling mu-opioid and gaba(b) receptors to ca2+ channels, but rather lend credence to the notion that the signalling mechanisms utilized by these two receptors might simply compete for inhibitory control of a common pool of n-type channels. |
1998-08-21 |
2023-08-12 |
rat |
| A Hayar, P Piguet, P Felt. GABA-induced responses in electrophysiologically characterized neurons within the rat rostro-ventrolateral medulla in vitro. Brain research. vol 709. issue 2. 1997-05-01. PMID:8833753. |
all neuronal types seem to have functional gaba a and gaba b receptors; however, only a subpopulation is under tonic inhibitory control in vitro, probably from local gabaergic pacemaker interneurons. |
1997-05-01 |
2023-08-12 |
rat |
| J M Luque, R Erat, R Kettler, A Cesura, M Da Prada, J G Richard. Radioautographic evidence that the GABAA receptor antagonist SR 95531 is a substrate inhibitor of MAO-A in the rat and human locus coeruleus. The European journal of neuroscience. vol 6. issue 6. 1994-12-07. PMID:7952273. |
lc neurons are under the inhibitory control of gamma-aminobutyric acid (gaba) via ionotropic gabaa receptors. |
1994-12-07 |
2023-08-12 |
human |
| U Jürgens, C L L. The effects of periaqueductally injected transmitter antagonists on forebrain-elicited vocalization in the squirrel monkey. The European journal of neuroscience. vol 5. issue 6. 1994-01-27. PMID:7903190. |
inhibitory control is exerted by gaba, glycine and endogenous opioids. |
1994-01-27 |
2023-08-12 |
monkey |
| A Imperato, L Dazzi, M C Obinu, G L Gessa, G Biggi. Inhibition of hippocampal acetylcholine release by benzodiazepines: antagonism by flumazenil. European journal of pharmacology. vol 238. issue 1. 1993-10-26. PMID:8405078. |
these results show that activation of benzodiazepine receptors reduces the in vivo release of acetylcholine in the hippocampus, suggesting that the septo-hippocampal cholinergic system, which has a major role in the regulation of cognitive functions, is under inhibitory control exerted by gamma-aminobutyrate (gaba) neurons. |
1993-10-26 |
2023-08-12 |
rat |
| S Retaux, J Caboche, M Rogard, J F Julien, J Penit-Soria, M J Besso. GABA interneurons in the rat medial frontal cortex: characterization by quantitative in situ hybridization of the glutamic acid decarboxylase (GAD67) mRNA. Brain research. vol 611. issue 2. 1993-08-26. PMID:8334513. |
the heterogeneity of gad67 mrna content at the cellular level might underlie the existence of subpopulations of gaba interneurons in the mfc and suggests a higher gabaergic inhibitory control in the anterior cingulate area than in the prelimbic area. |
1993-08-26 |
2023-08-12 |
rat |
| K Campbell, P Kalén, K Wictorin, C Lundberg, R J Mandel, A Björklun. Characterization of GABA release from intrastriatal striatal transplants: dependence on host-derived afferents. Neuroscience. vol 53. issue 2. 1993-06-11. PMID:8098510. |
the dopamine denervating lesion resulted in an increased k(+)-evoked gaba overflow both in the intact (+76%) and the grafted striata (+181%), suggesting that the tonic dopaminergic inhibitory control of gaba release, seen in the intact striatum, is also present in the grafted striata. |
1993-06-11 |
2023-08-12 |
rat |
| J X Hao, X J Xu, Y X Yu, A Seiger, Z Wiesenfeld-Halli. Baclofen reverses the hypersensitivity of dorsal horn wide dynamic range neurons to mechanical stimulation after transient spinal cord ischemia; implications for a tonic GABAergic inhibitory control of myelinated fiber input. Journal of neurophysiology. vol 68. issue 2. 1992-10-20. PMID:1527566. |
it is suggested that gabaergic interneurons exert a tonic presynaptic inhibitory control, through baclofen-sensitive b-type gaba receptors, on input from low-threshold mechanical afferents, and that disruption of this control may result in painful reaction to innocuous stimuli (allodynia). |
1992-10-20 |
2023-08-11 |
rat |
| S Bourgoin, M Pohl, J J Benoliel, A Mauborgne, E Collin, M Hamon, F Cesseli. gamma-Aminobutyric acid, through GABAA receptors, inhibits the potassium-stimulated release of calcitonin gene-related peptide- but not that of substance P-like material from rat spinal cord slices. Brain research. vol 583. issue 1-2. 1992-09-18. PMID:1380400. |
these data further support that gaba exerts a presynaptic inhibitory control of (cgrp-containing) primary afferent fibres within the rat dorsal horn. |
1992-09-18 |
2023-08-11 |
rat |
| M B Dutia, A R Johnston, D S McQuee. Tonic activity of rat medial vestibular nucleus neurones in vitro and its inhibition by GABA. Experimental brain research. vol 88. issue 3. 1992-06-19. PMID:1587312. |
these results suggest that the inhibitory control of mvn neurones by gaba involves both the gabaa and gabab subtypes of gaba receptor. |
1992-06-19 |
2023-08-11 |
rat |
| L Seress, C E Riba. Ultrastructural features of primate granule cell bodies show important differences from those of rats: axosomatic synapses, somatic spines and infolded nuclei. Brain research. vol 569. issue 2. 1992-04-03. PMID:1540835. |
since the granule cell body is an important site for gamma-aminobutyric acid (gaba)ergic inhibitory control, the reduced number of axosomatic synapses in monkeys suggests that local inhibitory connections of primate granule cells are less than that of rodents. |
1992-04-03 |
2023-08-11 |
rat |
| D Tomsic, H Maldonado, A Rakiti. Morphine and GABA: effects on perception, escape response and long-term habituation to a danger stimulus in the crab Chasmagnathus. Brain research bulletin. vol 26. issue 5. 1991-12-04. PMID:1933390. |
in one experiment, both morphine and gaba pretreatment produced similar mild response inhibition during training, but morphine, not gaba impaired long-term habituation. |
1991-12-04 |
2023-08-11 |
Not clear |
| D Becquet, M Faudon, F Her. In vivo evidence for an inhibitory glutamatergic control of serotonin release in the cat caudate nucleus: involvement of GABA neurons. Brain research. vol 519. issue 1-2. 1990-10-16. PMID:1975768. |
the inhibitory control exerted by l-glutamic acid on serotonergic transmission could involve gamma-aminobutyric acid interneurons. |
1990-10-16 |
2023-08-11 |
cat |