| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tsugunobu Andoh, Ayumi Sakamoto, Yasushi Kuraish. 5-HT1A receptor agonists, xaliproden and tandospirone, inhibit the increase in the number of cutaneous mast cells involved in the exacerbation of mechanical allodynia in oxaliplatin-treated mice. Journal of pharmacological sciences. vol 131. issue 4. 2017-06-30. PMID:27562704. |
5-ht1a receptor agonists, xaliproden and tandospirone, inhibit the increase in the number of cutaneous mast cells involved in the exacerbation of mechanical allodynia in oxaliplatin-treated mice. |
2017-06-30 |
2023-08-13 |
mouse |
| Tsugunobu Andoh, Ayumi Sakamoto, Yasushi Kuraish. 5-HT1A receptor agonists, xaliproden and tandospirone, inhibit the increase in the number of cutaneous mast cells involved in the exacerbation of mechanical allodynia in oxaliplatin-treated mice. Journal of pharmacological sciences. vol 131. issue 4. 2017-06-30. PMID:27562704. |
repetitive administration of 5-ht1a receptor agonists (xaliproden and tandospirone) inhibited mechanical allodynia induced by a single intraperitoneal injection of oxaliplatin. |
2017-06-30 |
2023-08-13 |
mouse |
| Thomas Pokorny, Katrin H Preller, Rainer Kraehenmann, Franz X Vollenweide. Modulatory effect of the 5-HT1A agonist buspirone and the mixed non-hallucinogenic 5-HT1A/2A agonist ergotamine on psilocybin-induced psychedelic experience. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 4. 2017-05-03. PMID:26875114. |
modulatory effect of the 5-ht1a agonist buspirone and the mixed non-hallucinogenic 5-ht1a/2a agonist ergotamine on psilocybin-induced psychedelic experience. |
2017-05-03 |
2023-08-13 |
human |
| Thomas Pokorny, Katrin H Preller, Rainer Kraehenmann, Franz X Vollenweide. Modulatory effect of the 5-HT1A agonist buspirone and the mixed non-hallucinogenic 5-HT1A/2A agonist ergotamine on psilocybin-induced psychedelic experience. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 4. 2017-05-03. PMID:26875114. |
therefore, we used a double-blind, counterbalanced, within-subject design to investigate the modulatory effects of the partial 5-ht1a agonist buspirone (20mg p.o.) |
2017-05-03 |
2023-08-13 |
human |
| Thomas Pokorny, Katrin H Preller, Rainer Kraehenmann, Franz X Vollenweide. Modulatory effect of the 5-HT1A agonist buspirone and the mixed non-hallucinogenic 5-HT1A/2A agonist ergotamine on psilocybin-induced psychedelic experience. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 4. 2017-05-03. PMID:26875114. |
the present finding demonstrates that buspirone exerts inhibitory effects on psilocybin-induced effects, presumably via 5-ht1a receptor activation, an interaction between 5-ht1a and 5-ht2a receptors, or both. |
2017-05-03 |
2023-08-13 |
human |
| Jeffrey P Cheng, Jacob B Leary, Aerin Sembhi, Clarice M Edwards, Corina O Bondi, Anthony E Klin. 5-hydroxytryptamine1A (5-HT1A) receptor agonists: A decade of empirical evidence supports their use as an efficacious therapeutic strategy for brain trauma. Brain research. vol 1640. issue Pt A. 2017-05-01. PMID:26612522. |
an approach that has undergone considerable empirical research after tbi is pharmacological targeting of 5-ht1a receptors with agonists such as repinotan hcl, 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat), and buspirone. |
2017-05-01 |
2023-08-13 |
Not clear |
| V A Mikhailenko, I P Butkevic. The Role of 5-HT1A Receptors in Long-Term Adaptation of Newborn Rats to Hypoxia. Bulletin of experimental biology and medicine. vol 161. issue 4. 2017-03-08. PMID:27591870. |
we studied the effects of neonatal hypoxia on adaptive behavior of rats during prepubertal and pubertal periods in the control and after repeated injections of 5-ht1a receptor agonist buspirone. |
2017-03-08 |
2023-08-13 |
rat |
| V A Mikhailenko, I P Butkevic. The Role of 5-HT1A Receptors in Long-Term Adaptation of Newborn Rats to Hypoxia. Bulletin of experimental biology and medicine. vol 161. issue 4. 2017-03-08. PMID:27591870. |
the protective effect of buspirone can result from strengthening of the adaptive potencies of the serotoninergic system via activation of 5-ht1a receptors that up-regulate secretion of trophic factor s100β under conditions of serotonin deficiency typical of rats exposed to neonatal hypoxia. |
2017-03-08 |
2023-08-13 |
rat |
| Zeyad T Sahli, Pradeep Banerjee, Frank I Taraz. The Preclinical and Clinical Effects of Vilazodone for the Treatment of Major Depressive Disorder. Expert opinion on drug discovery. vol 11. issue 5. 2016-12-30. PMID:26971593. |
augmentation of the leading class of antidepressant treatment, selective serotonin reuptake inhibitors (ssris), with the 5-ht1a receptor agonist buspirone has been shown to be effective in treating patients that do not respond to initial ssri therapy. |
2016-12-30 |
2023-08-13 |
Not clear |
| Masakuni Horiguchi, Masanori Miyauchi, Nichole M Neugebauer, Yoshihiro Oyamada, Herbert Y Meltze. Prolonged reversal of the phencyclidine-induced impairment in novel object recognition by a serotonin (5-HT)1A-dependent mechanism. Behavioural brain research. vol 301. 2016-10-20. PMID:26342283. |
we examined the ability of post-pcp subchronic lurasidone, an atypical apd with potent serotonin (5-ht)1a partial agonism and subchronic tandospirone, a selective 5-ht1a partial agonist, to enable prolonged reversal of the subchronic pcp-induced nor deficit. |
2016-10-20 |
2023-08-13 |
rat |
| Diane C Chugani, Harry T Chugani, Max Wiznitzer, Sumit Parikh, Patricia A Evans, Robin L Hansen, Ruth Nass, James J Janisse, Pamela Dixon-Thomas, Michael Behen, Robert Rothermel, Jacqueline S Parker, Ajay Kumar, Otto Muzik, David J Edwards, Deborah Hirt. Efficacy of Low-Dose Buspirone for Restricted and Repetitive Behavior in Young Children with Autism Spectrum Disorder: A Randomized Trial. The Journal of pediatrics. vol 170. 2016-07-26. PMID:26746121. |
to determine safety and efficacy of the 5ht1a serotonin partial agonist buspirone on core autism and associated features in children with autism spectrum disorder (asd). |
2016-07-26 |
2023-08-13 |
Not clear |
| Nausheen Alam, Rahila Najam, Sadaf Naee. Attenuation of methylphenidate-induced sensitization by co-administration of buspirone. Pakistan journal of pharmaceutical sciences. vol 29. issue 2. 2016-06-30. PMID:27087081. |
repeated buspirone administration reduces the effectiveness of 5-ht1a somatodendritic receptors. |
2016-06-30 |
2023-08-13 |
Not clear |
| Nausheen Alam, Rahila Najam, Sadaf Naee. Attenuation of methylphenidate-induced sensitization by co-administration of buspirone. Pakistan journal of pharmaceutical sciences. vol 29. issue 2. 2016-06-30. PMID:27087081. |
it is suggested that the sensitization development to methylphenidate may oppose by buspirone co-administration due to the reduction in the sensitivity of 5-ht1a somatodendritic receptors. |
2016-06-30 |
2023-08-13 |
Not clear |
| A Sagarduy, J Llorente, C Miguelez, T Morera-Herreras, J A Ruiz-Ortega, L Uged. Buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors. Experimental neurology. vol 277. 2016-06-27. PMID:26687972. |
buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-ht1a receptors. |
2016-06-27 |
2023-08-13 |
rat |
| A Sagarduy, J Llorente, C Miguelez, T Morera-Herreras, J A Ruiz-Ortega, L Uged. Buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors. Experimental neurology. vol 277. 2016-06-27. PMID:26687972. |
cell-attached recordings in parasagittal slices from naïve rats showed that whilst serotonin excited the majority of stn neurons, buspirone showed an inhibitory main effect but only in 27% of the studied cells which was prevented by the 5-ht1a receptor selective antagonist way-100635. |
2016-06-27 |
2023-08-13 |
rat |
| A Sagarduy, J Llorente, C Miguelez, T Morera-Herreras, J A Ruiz-Ortega, L Uged. Buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors. Experimental neurology. vol 277. 2016-06-27. PMID:26687972. |
altogether, buspirone in vivo reduces consistently the firing rate of the stn neurons through 5-ht1a receptors whereas ex vivo buspirone seems to affect only a small population of stn neurons. |
2016-06-27 |
2023-08-13 |
rat |
| A Sagarduy, J Llorente, C Miguelez, T Morera-Herreras, J A Ruiz-Ortega, L Uged. Buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors. Experimental neurology. vol 277. 2016-06-27. PMID:26687972. |
furthermore, the lack of effect of buspirone in 6-ohda lesioned rats, suggests the requirement of not only the activation of 5-ht1a receptors but also an intact nigrostriatal pathway for buspirone to inhibit the stn activity. |
2016-06-27 |
2023-08-13 |
rat |
| Aimee L McRae-Clark, Nathaniel L Baker, Kevin M Gray, Therese K Killeen, Amanda M Wagner, Kathleen T Brady, C Lindsay DeVane, Jessica Norto. Buspirone treatment of cannabis dependence: A randomized, placebo-controlled trial. Drug and alcohol dependence. vol 156. 2016-06-13. PMID:26386827. |
the purpose of this study was to evaluate the efficacy of buspirone, a partial 5-ht1a agonist, for treatment of cannabis dependence. |
2016-06-13 |
2023-08-13 |
Not clear |
| Xia Li, Katarzyna Kaczanowska, M G Finn, Athina Markou, Victoria B Risbroug. The GABA(B) receptor positive modulator BHF177 attenuated anxiety, but not conditioned fear, in rats. Neuropharmacology. vol 97. 2016-05-24. PMID:26002628. |
the effects of bhf177 on les were compared with those of the gabab receptor agonists baclofen and cgp44532, and the positive control buspirone, a 5-ht1a receptor partial agonist with anxiolytic activity in humans. |
2016-05-24 |
2023-08-13 |
rat |
| Ken-Ichi Kasahara, Shinji Hashimoto, Tsuyoshi Hattori, Koh Kawasaki, Ryuichi Tsujita, Osamu Nakazono, Katsuyuki Takao, Hiromu Kawakubo, Tadashi Nagatan. The effects of AP521, a novel anxiolytic drug, in three anxiety models and on serotonergic neural transmission in rats. Journal of pharmacological sciences. vol 127. issue 1. 2016-04-25. PMID:25704026. |
tandospirone, which can stimulate the presynaptic 5-ht1a receptors in the raphe, tended to decrease extracellular 5-ht concentration in the medial prefrontal cortex (mpfc) in rats. |
2016-04-25 |
2023-08-13 |
human |