| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Carli, P Bonalumi, R Samani. Stimulation of 5-HT1A receptors in the dorsal raphe reverses the impairment of spatial learning caused by intrahippocampal scopolamine in rats. The European journal of neuroscience. vol 10. issue 1. 1998-10-08. PMID:9753130. |
this study investigated the effect of stimulating 5-ht1a receptors in the dorsal raphe on the impairment of learning caused by 4 microg/microl scopolamine injected in the ca1 region of the dorsal hippocampus in rats performing a two-platform spatial discrimination task. |
1998-10-08 |
2023-08-12 |
rat |
| I Izquierdo, J H Medina, L A Izquierdo, D M Barros, M M de Souza, T Mello e Souz. Short- and long-term memory are differentially regulated by monoaminergic systems in the rat brain. Neurobiology of learning and memory. vol 69. issue 3. 1998-10-06. PMID:9707486. |
several drugs infused immediately post-training inhibited stm without altering ltm: the d1 receptor agonist skf38393 (7.5 microgram) given into either ca1 or ec, the beta blocker timolol (0.3 microgram) given into ec, the 5ht1a receptor agonist 8-ho-dpat (2.5 microgram) given into ca1, and the 5ht1a antagonist nan-190 (2.5 microgram) given into ec. |
1998-10-06 |
2023-08-12 |
rat |
| I Izquierdo, J H Medina, L A Izquierdo, D M Barros, M M de Souza, T Mello e Souz. Short- and long-term memory are differentially regulated by monoaminergic systems in the rat brain. Neurobiology of learning and memory. vol 69. issue 3. 1998-10-06. PMID:9707486. |
the data indicate that stm and ltm are differentially modulated by d1, beta, and 5ht1a receptors in ca1 and ec. |
1998-10-06 |
2023-08-12 |
rat |
| A M Pugliese, M B Passani, R Corradett. Effect of the selective 5-HT1A receptor antagonist WAY 100635 on the inhibition of e.p.s.ps produced by 5-HT in the CA1 region of rat hippocampal slices. British journal of pharmacology. vol 124. issue 1. 1998-08-04. PMID:9630348. |
effect of the selective 5-ht1a receptor antagonist way 100635 on the inhibition of e.p.s.ps produced by 5-ht in the ca1 region of rat hippocampal slices. |
1998-08-04 |
2023-08-12 |
rat |
| A M Pugliese, M B Passani, R Corradett. Effect of the selective 5-HT1A receptor antagonist WAY 100635 on the inhibition of e.p.s.ps produced by 5-HT in the CA1 region of rat hippocampal slices. British journal of pharmacology. vol 124. issue 1. 1998-08-04. PMID:9630348. |
the actions of n-(2-(-4(2-methoxyphenyl)-1-piperazinyl)ethyl)-n-(2-pyridinyl) cyclohexane carboxamide (way 100635), a novel and selective 5-hydroxytryptamine1a (5-ht1a) antagonist, on excitatory postsynaptic potentials (e.p.s.ps) were investigated by use of intracellular recordings in pyramidal cells of the ca1 region of rat hippocampal slices. |
1998-08-04 |
2023-08-12 |
rat |
| A M Pugliese, M B Passani, R Corradett. Effect of the selective 5-HT1A receptor antagonist WAY 100635 on the inhibition of e.p.s.ps produced by 5-HT in the CA1 region of rat hippocampal slices. British journal of pharmacology. vol 124. issue 1. 1998-08-04. PMID:9630348. |
since way 100635 selectively antagonizes 5-ht1a receptor-mediated actions of 5-ht, our data also demonstrate that the inhibitory action of 5-ht on excitatory synaptic transmission in ca1 is mediated by 5-ht1a receptors. |
1998-08-04 |
2023-08-12 |
rat |
| S Rasmuson, T Olsson, B G Henriksson, P A Kelly, M C Holmes, J R Seckl, A H Mohamme. Environmental enrichment selectively increases 5-HT1A receptor mRNA expression and binding in the rat hippocampus. Brain research. Molecular brain research. vol 53. issue 1-2. 1998-04-20. PMID:9473697. |
rats from the enriched group had significantly higher 5-ht1a receptor mrna expression in the dorsal hippocampus (62%, 59% and 44% increase in the ca1, ca2 and ca3 subfields, respectively). |
1998-04-20 |
2023-08-12 |
rat |
| R Corradetti, N Laaris, N Hanoun, A M Laporte, E Le Poul, M Hamon, L Lanfume. Antagonist properties of (-)-pindolol and WAY 100635 at somatodendritic and postsynaptic 5-HT1A receptors in the rat brain. British journal of pharmacology. vol 123. issue 3. 1998-04-13. PMID:9504386. |
studies were performed on 5-ht1a receptors located on 5-hydroxytryptaminergic neurones in the dorsal raphe nucleus (drn) and on pyramidal cells in the ca1 and ca3 regions of the hippocampus in rat brain slices. |
1998-04-13 |
2023-08-12 |
rat |
| R Corradetti, A M Pugliese, E Le Poul, N Laaris, M Hamon, L Lanfume. Electrophysiological effects of WAY 100635, a new 5-HT1A receptor antagonist, on dorsal raphe nucleus serotoninergic neurones and CA1 pyramidal cells in vitro. Acta physiologica Hungarica. vol 84. issue 4. 1998-02-02. PMID:9328615. |
the antagonism of the hyperpolarisation elicited by 5-ct was competitive in the drn and non competitive in ca1, probably because of the existence of a 5-ht1a receptor reserve in serotoninergic cells of drn. |
1998-02-02 |
2023-08-12 |
Not clear |
| C Nyakas, B J Oosterink, J Keijser, K Felszeghy, G I de Jong, J Korf, P G Luite. Selective decline of 5-HT1A receptor binding sites in rat cortex, hippocampus and cholinergic basal forebrain nuclei during aging. Journal of chemical neuroanatomy. vol 13. issue 1. 1997-09-29. PMID:9271195. |
no change or only a slight decrease of the 5-ht1a receptor density was found in other areas investigated: the ca1 and ca3 sectors of hippocampus, the cingular and perirhinal cerebral cortex and the lateral septum. |
1997-09-29 |
2023-08-12 |
rat |
| S Le Corre, T Sharp, A H Young, P J Harriso. Increase of 5-HT7 (serotonin-7) and 5-HT1A (serotonin-1A) receptor mRNA expression in rat hippocampus after adrenalectomy. Psychopharmacology. vol 130. issue 4. 1997-08-12. PMID:9160853. |
adrenalectomy was associated with a marked increase of 5-ht1a receptor mrna in dentate gyrus, ca3 and ca2, but not in ca1, nor in the raphe. |
1997-08-12 |
2023-08-12 |
rat |
| K Tokarski, M Bija. Antidepressant-induced adaptive changes in the effects of 5-HT, 5-HT1A and 5-HT4 agonists on the population spike recorded in hippocampal CA1 cells do not involve presynaptic effects on excitatory synaptic transmission. Polish journal of pharmacology. vol 48. issue 6. 1997-06-26. PMID:9112695. |
antidepressant-induced adaptive changes in the effects of 5-ht, 5-ht1a and 5-ht4 agonists on the population spike recorded in hippocampal ca1 cells do not involve presynaptic effects on excitatory synaptic transmission. |
1997-06-26 |
2023-08-12 |
rat |
| K Tokarski, M Bija. Antidepressant-induced adaptive changes in the effects of 5-HT, 5-HT1A and 5-HT4 agonists on the population spike recorded in hippocampal CA1 cells do not involve presynaptic effects on excitatory synaptic transmission. Polish journal of pharmacology. vol 48. issue 6. 1997-06-26. PMID:9112695. |
effects of repeated treatment with antidepressant drugs on the reactivity of ca1 neurons to 5-hydroxytryptamine (5-ht), (+/-)-8-hydroxy-2-(dipropyl-amino)-tetralin (8-oh-dpat)--the 5-ht1a receptor agonist, and the zacopride-5-ht4 receptor agonist were examined in the rat hippocampus ex vivo. |
1997-06-26 |
2023-08-12 |
rat |
| I Belcheva, S Belcheva, V V Petkov, C Hadjiivanova, V D Petko. Behavorial responses to the 5-HT1A receptor antagonist NAN190 injected into rat CA1 hippocampal area. General pharmacology. vol 28. issue 3. 1997-06-05. PMID:9068987. |
behavorial responses to the 5-ht1a receptor antagonist nan190 injected into rat ca1 hippocampal area. |
1997-06-05 |
2023-08-12 |
rat |
| I Belcheva, S Belcheva, V V Petkov, C Hadjiivanova, V D Petko. Behavorial responses to the 5-HT1A receptor antagonist NAN190 injected into rat CA1 hippocampal area. General pharmacology. vol 28. issue 3. 1997-06-05. PMID:9068987. |
behavioral responses to unilateral and bilateral microinjections of the 5-ht1a receptor antagonist, nan190 [1-(2-methoxyphenyl)-4-[4-(2-phthalimido) butyl]piperazine hydrobromide] (1 microgram), into the hippocampal ca1 area of male wistar rats were studied. |
1997-06-05 |
2023-08-12 |
rat |
| I Belcheva, S Belcheva, V V Petkov, C Hadjiivanova, V D Petko. Behavorial responses to the 5-HT1A receptor antagonist NAN190 injected into rat CA1 hippocampal area. General pharmacology. vol 28. issue 3. 1997-06-05. PMID:9068987. |
the different behavioral responses to left and right microinjections of nan190 in some of the behavioral tests suggest functional asymmetry of 5-ht1a receptors in the ca1 hippocampal area. |
1997-06-05 |
2023-08-12 |
rat |
| S G Beck, S Birnstiel, K C Choi, W A Poulio. Fluoxetine selectively alters 5-hydroxytryptamine1A and gamma-aminobutyric acidB receptor-mediated hyperpolarization in area CA1, but not area CA3, hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics. vol 281. issue 1. 1997-05-02. PMID:9103487. |
the hippocampal pyramidal cell characteristics and the 5-ht1a and gaba(b) receptor-mediated hyperpolarization were measured in the ca1 and the ca3 subfields. |
1997-05-02 |
2023-08-12 |
rat |
| S G Beck, S Birnstiel, K C Choi, W A Poulio. Fluoxetine selectively alters 5-hydroxytryptamine1A and gamma-aminobutyric acidB receptor-mediated hyperpolarization in area CA1, but not area CA3, hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics. vol 281. issue 1. 1997-05-02. PMID:9103487. |
fluoxetine treatment increased the potency of 5-ht for the 5-ht1a receptor-mediated hyperpolarization in area ca1, but not area ca3, and decreased the potency of baclofen for the gaba(b) receptor-mediated hyperpolarization in area ca1, but not area ca3. |
1997-05-02 |
2023-08-12 |
rat |
| S G Beck, S Birnstiel, K C Choi, W A Poulio. Fluoxetine selectively alters 5-hydroxytryptamine1A and gamma-aminobutyric acidB receptor-mediated hyperpolarization in area CA1, but not area CA3, hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics. vol 281. issue 1. 1997-05-02. PMID:9103487. |
chronic fluoxetine selectively and differentially altered the cell characteristics and the 5-ht1a and gaba(b) receptor-mediated responses in area ca1 of the hippocampus, which forms the final common output of the hippocampus. |
1997-05-02 |
2023-08-12 |
rat |
| D Salgado-Commissariat, K A Alkadh. Effects of serotonin on induced epileptiform activity in CA1 pyramidal neurons of genetically epilepsy prone rats. Brain research. vol 743. issue 1-2. 1997-04-17. PMID:9017248. |
the effects of the selective serotonin 5-ht1a receptor agonist, 8-oh-dpat (20 microm) on gepr-9 pyramidal ca1 neurons were similar to those of serotonin, except the magnitude of hyperpolarization and reduction of membrane input resistance were less than those produced by serotonin. |
1997-04-17 |
2023-08-12 |
rat |