| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S M Korte, O C Meijer, E R de Kloet, B Buwalda, J Keijser, F Sluyter, G van Oortmerssen, B Bohu. Enhanced 5-HT1A receptor expression in forebrain regions of aggressive house mice. Brain research. vol 736. issue 1-2. 1997-02-26. PMID:8930340. |
at that time the level of 5-ht1a mrna in the dorsal hippocampus (dentate gyrus and ca1) was twice the amount measured in low-aggressive mice that had long attack latency and high plasma corticosterone level. |
1997-02-26 |
2023-08-12 |
mouse |
| S M Korte, O C Meijer, E R de Kloet, B Buwalda, J Keijser, F Sluyter, G van Oortmerssen, B Bohu. Enhanced 5-HT1A receptor expression in forebrain regions of aggressive house mice. Brain research. vol 736. issue 1-2. 1997-02-26. PMID:8930340. |
increased postsynaptic 5-ht1a receptor radioligand binding was found in dentate gyrus, ca1, lateral septum, and frontal cortex. |
1997-02-26 |
2023-08-12 |
mouse |
| M Bijak, K Tokarski, A Czyrak, M Maćkowiak, K Wedzon. Imipramine increases the 5-HT1A receptor-mediated inhibition of hippocampal neurons without changing the 5-HT1A receptor binding. European journal of pharmacology. vol 305. issue 1-3. 1997-02-20. PMID:8813535. |
the effect of repeated treatment with imipramine on the 5-ht1a receptor-mediated inhibition of a population spike was studied in the rat ca1 hippocampal region ex vivo. |
1997-02-20 |
2023-08-12 |
rat |
| B Grijalba, L F Callado, J Javier Meana, J A García-Sevilla, A Pazo. Alpha 2-adrenoceptor subtypes in the human brain: a pharmacological delineation of [3H]RX-821002 binding to membranes and tissue sections. European journal of pharmacology. vol 310. issue 1. 1997-01-30. PMID:8880071. |
in the hippocampus, both alpha 2a- and non-alpha 2a- (alpha 2b- and alpha 2c-) adrenoceptors were labelled in the dentate gyrus and the ca1 field, together with 5-ht1a receptors. |
1997-01-30 |
2023-08-12 |
human |
| A Fletcher, E A Forster, D J Bill, G Brown, I A Cliffe, J E Hartley, D E Jones, A McLenachan, K J Stanhope, D J Critchley, K J Childs, V C Middlefell, L Lanfumey, R Corradetti, A M Laporte, H Gozlan, M Hamon, C T Douris. Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788530. |
in vitro electrophysiological studies demonstrated that way-100635 had no 5-ht1a receptor agonist actions, but dose-dependently blocked the effects of agonists at both the postsynaptic 5-ht1a receptor in the ca1 region of the hippocampus, and the somatodendritic 5-ht1a receptor located on dorsal raphe 5-ht neurones. |
1996-12-04 |
2023-08-12 |
mouse |
| S G Beck, K C Choi, T J List, D Y Okuhara, S Birnstei. Corticosterone alters 5-HT1A receptor-mediated hyperpolarization in area CA1 hippocampal pyramidal neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 14. issue 1. 1996-09-20. PMID:8719027. |
corticosterone alters 5-ht1a receptor-mediated hyperpolarization in area ca1 hippocampal pyramidal neurons. |
1996-09-20 |
2023-08-12 |
rat |
| S G Beck, K C Choi, T J List, D Y Okuhara, S Birnstei. Corticosterone alters 5-HT1A receptor-mediated hyperpolarization in area CA1 hippocampal pyramidal neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 14. issue 1. 1996-09-20. PMID:8719027. |
the 5-hydroxytryptamine1a (5-ht1a) receptor in the ca1 region of the hippocampus is linked through a g protein to an inwardly rectifying potassium conductance. |
1996-09-20 |
2023-08-12 |
rat |
| S G Beck, K C Choi, T J List, D Y Okuhara, S Birnstei. Corticosterone alters 5-HT1A receptor-mediated hyperpolarization in area CA1 hippocampal pyramidal neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 14. issue 1. 1996-09-20. PMID:8719027. |
some laboratories have reported that ct modulates 5-ht1a receptor binding density and mrna levels in area ca1 of the hippocampus; however, others have reported no change. |
1996-09-20 |
2023-08-12 |
rat |
| S G Beck, K C Choi, T J List, D Y Okuhara, S Birnstei. Corticosterone alters 5-HT1A receptor-mediated hyperpolarization in area CA1 hippocampal pyramidal neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 14. issue 1. 1996-09-20. PMID:8719027. |
we conclude that the 5-ht1a receptor-effector system in ca1 hippocampal pyramidal neurons is modulated by ct in a dose- and time-dependent manner. |
1996-09-20 |
2023-08-12 |
rat |
| R Corradetti, E Le Poul, N Laaris, M Hamon, L Lanfume. Electrophysiological effects of N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl) cyclohexane carboxamide (WAY 100635) on dorsal raphe serotonergic neurons and CA1 hippocampal pyramidal cells in vitro. The Journal of pharmacology and experimental therapeutics. vol 278. issue 2. 1996-09-18. PMID:8768719. |
the aim of the present study was to examine the effects of n-(2-(4-2-methoxphenyl)-1-piperazinyl)ethyl)-n-(2-pyridnyl) cyclohexane carboxamide (way 100635) on 5-ht1a receptor-mediated responses in the dorsal raphe nucleus (drn) and the ca1 hippocampal region. |
1996-09-18 |
2023-08-12 |
Not clear |
| R Corradetti, E Le Poul, N Laaris, M Hamon, L Lanfume. Electrophysiological effects of N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl) cyclohexane carboxamide (WAY 100635) on dorsal raphe serotonergic neurons and CA1 hippocampal pyramidal cells in vitro. The Journal of pharmacology and experimental therapeutics. vol 278. issue 2. 1996-09-18. PMID:8768719. |
these data show the way 100635 is a potent antagonist at 5-ht1a receptors, both in the drn and in the ca1 region of the hippocampus. |
1996-09-18 |
2023-08-12 |
Not clear |
| H Chen, L Zhang, D R Rubinow, D M Chuan. Chronic buspirone treatment differentially regulates 5-HT1A and 5-HT2A receptor mRNA and binding sites in various regions of the rat hippocampus. Brain research. Molecular brain research. vol 32. issue 2. 1996-01-18. PMID:7500848. |
after buspirone treatment, the 5-ht1a receptor mrna levels were significantly decreased in the ca1 and ca2 of the hippocampus, but were markedly increased in the dentate gyrus (dg), ca3 and ca4. |
1996-01-18 |
2023-08-12 |
rat |
| D Schmitz, R M Empson, U Heineman. Serotonin reduces inhibition via 5-HT1A receptors in area CA1 of rat hippocampal slices in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 11. 1995-12-26. PMID:7472476. |
serotonin reduces inhibition via 5-ht1a receptors in area ca1 of rat hippocampal slices in vitro. |
1995-12-26 |
2023-08-12 |
rat |
| P W Burnet, S L Eastwood, K Lacey, P J Harriso. The distribution of 5-HT1A and 5-HT2A receptor mRNA in human brain. Brain research. vol 676. issue 1. 1995-08-03. PMID:7796165. |
in the hippocampus, 5-ht1a receptor mrna was present in all fields, especially ca1. |
1995-08-03 |
2023-08-12 |
human |
| C R McKittrick, D C Blanchard, R J Blanchard, B S McEwen, R R Saka. Serotonin receptor binding in a colony model of chronic social stress. Biological psychiatry. vol 37. issue 6. 1995-07-07. PMID:7772647. |
in addition, 5-ht1a binding was decreased in ca1, ca3, and ca4 in dominants compared to controls. |
1995-07-07 |
2023-08-12 |
rat |
| S G Beck, S Birnstiel, W A Pouliot, K C Cho. Baclofen concentration-response curves differ between hippocampal subfields. Neuroreport. vol 6. issue 2. 1995-06-23. PMID:7756617. |
agonist potency and the maximal hyperpolarization produced by 5-ht1a receptor activation is different between the ca1 and ca3 subfields. |
1995-06-23 |
2023-08-12 |
Not clear |
| M Carli, R Luschi, P Garofalo, R Samani. 8-OH-DPAT impairs spatial but not visual learning in a water maze by stimulating 5-HT1A receptors in the hippocampus. Behavioural brain research. vol 67. issue 1. 1995-06-21. PMID:7748502. |
infusion of 1 microgram/microliter spiroxatrine (spx) or 5 micrograms/microliters of (+)way100135, two potent 5-ht1a receptor antagonists, in the ca1 region of the dorsal hippocampus antagonized the impairment in choice accuracy caused by 8-oh-dpat. |
1995-06-21 |
2023-08-12 |
rat |
| M Carli, R Luschi, P Garofalo, R Samani. 8-OH-DPAT impairs spatial but not visual learning in a water maze by stimulating 5-HT1A receptors in the hippocampus. Behavioural brain research. vol 67. issue 1. 1995-06-21. PMID:7748502. |
the results suggest that stimulation of 5-ht1a receptors in the ca1 region of the dorsal hippocampus impairs spatial but not visual discrimination in rats. |
1995-06-21 |
2023-08-12 |
rat |
| D Manahan-Vaughan, R Anwyl, M J Rowa. Adaptive changes in 5-HT1A receptor-mediated hippocampal inhibition in the alert rat produced by repeated 8-OH-DPAT treatment. British journal of pharmacology. vol 112. issue 4. 1994-12-20. PMID:7952867. |
the effect of acute and repeated treatment with 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat), a 5-ht1a receptor ligand, on excitatory amino acid-mediated synaptic transmission was examined in the stratum radiatum ca1 region of the dorsal hippocampus of alert, gently restrained, rats. |
1994-12-20 |
2023-08-12 |
rat |
| M R Pranzatelli, M M Durkin, A I Barka. Quantitative autoradiography of 5-hydroxytryptamine1A binding sites in rats with chronic neonatal 5,7-dihydroxytryptamine lesions. Brain research. Developmental brain research. vol 80. issue 1-2. 1994-12-20. PMID:7955334. |
the regional distribution of 5-ht1a sites conformed to previous reports of highest receptor densities in hippocampus (ca1, dentate gyrus), septal nuclei, dorsal and median raphe, mammillary body, and certain cortical regions (cingulum, claustrum). |
1994-12-20 |
2023-08-12 |
rat |