| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Fiorella, S Helsley, R A Rabin, J C Winte. 5-HT2C receptor-mediated phosphoinositide turnover and the stimulus effects of m-chlorophenylpiperazine. Psychopharmacology. vol 122. issue 3. 1996-09-26. PMID:8748393. |
the present data suggest that mcpp elicits a compound stimulus which is mediated by agonist interactions at the 5-ht2c receptor and possibly additional interactions with 5-ht2a, 5-ht3, and/or 5-ht1b receptors. |
1996-09-26 |
2023-08-12 |
Not clear |
| G J Molderings, D Frölich, J Likungu, M Göther. Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium. Naunyn-Schmiedeberg's archives of pharmacology. vol 353. issue 3. 1996-08-23. PMID:8692281. |
the inhibitory potency of the drugs was significantly correlated with their affinity for 5-htid receptors in human brain and for cloned human 5-ht1d alpha and 5-ht1d beta receptors, but not with their affinity for 5-ht1b, 5-ht1e, 5-ht1f, 5-ht2a, 5-ht2b, 5-ht2c, 5-ht3, 5-ht5a, 5-ht5b and 5-ht7 receptors. |
1996-08-23 |
2023-08-12 |
human |
| X C Li, J F Giot, D Kuhl, R Hen, E R Kande. Cloning and characterization of two related serotonergic receptors from the brain and the reproductive system of Aplysia that activate phospholipase C. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 11. 1995-12-26. PMID:7472509. |
sequence comparison reveals that these receptors are 33.1 to 23.3% identical to the following 5-ht receptors: 5-htdro1 > 5-ht6 > 5-htlym > mouse 5-ht1b > 5-htdro2a > mouse 5-ht7 > rat 5-ht2a. |
1995-12-26 |
2023-08-12 |
mouse |
| F Chaoulof. Regulation of 5-HT receptors by corticosteroids: where do we stand? Fundamental & clinical pharmacology. vol 9. issue 3. 1995-11-21. PMID:7557817. |
among the dozen of 5-ht receptors identified so far, four receptors (namely the 5-ht1a, 5-ht1b, 5-ht2a, and 5-ht2c receptors)--and the 5-ht uptake system--have been the focus of studies aimed at detecting corticosteroid modulatory effects. |
1995-11-21 |
2023-08-12 |
rat |
| F Chaoulof. Regulation of 5-HT receptors by corticosteroids: where do we stand? Fundamental & clinical pharmacology. vol 9. issue 3. 1995-11-21. PMID:7557817. |
however, because the data regarding a corticosteroid control of other 5-ht receptors are either scarce and contradictory (eg 5-ht1b, 5-ht2a, 5-ht2c receptors and 5-ht uptake systems) or lacking, it is at the present time unknown whether corticosteroids exert other effects on 5-ht receptor-mediated functions, including those related to homeostasis. |
1995-11-21 |
2023-08-12 |
rat |
| P A Pierce, G X Xie, S J Peroutka, P G Green, J D Levin. 5-Hydroxytryptamine-induced synovial plasma extravasation is mediated via 5-hydroxytryptamine2A receptors on sympathetic efferent terminals. The Journal of pharmacology and experimental therapeutics. vol 275. issue 1. 1995-11-21. PMID:7562592. |
polymerase chain reaction amplification of 5-ht receptor cdna demonstrates that 5-ht1a, 5-ht1b, 5-ht1d, 5-ht2a and 5-ht3, but not the 5-ht2c, receptor subtypes are present in lumbar sympathetic ganglia. |
1995-11-21 |
2023-08-12 |
rat |
| P M Callahan, K A Cunningha. Modulation of the discriminative stimulus properties of cocaine by 5-HT1B and 5-HT2C receptors. The Journal of pharmacology and experimental therapeutics. vol 274. issue 3. 1995-10-25. PMID:7562516. |
the present study assessed compounds displaying affinity for 5-ht1a, 5-ht1b, 5-ht2a and 5-ht2c receptors for their ability to substitute for, enhance or antagonize the discriminative stimulus effects of cocaine (10 mg/kg) in rats. |
1995-10-25 |
2023-08-12 |
rat |
| E Chojnacka-Wójcik, A Kłodzińska, A Dereń-Wesołe. Involvement of 5-HT2C receptors in the m-CPP-induced antinociception in mice. Polish journal of pharmacology. vol 46. issue 5. 1995-04-24. PMID:7894529. |
on the other hand, spiperone (0.25-0.5 mg/kg), a dopamine, 5-ht1a and 5-ht2a receptor antagonist; pindolol (4-8 mg/kg), a beta-adrenoceptor, 5-ht1a and 5-ht1b receptor antagonist and zacopride (0.1-1 mg/kg) a 5-ht3 receptor antagonist, did not affect the analgesia induced by m-cpp. |
1995-04-24 |
2023-08-12 |
mouse |
| A Choppin, S E O'Conno. Presence of vasoconstrictor 5HT1-like receptors revealed by precontraction of rabbit isolated mesenteric artery. British journal of pharmacology. vol 114. issue 2. 1995-04-10. PMID:7881730. |
pindolol (5-ht1a/5-ht1b), propranolol (5-ht1b), spiperone (5-ht2a), ondansetron (5-ht3), ics 205930 (5-ht3/5-ht4) and sdz 205557 (5-ht4). |
1995-04-10 |
2023-08-12 |
rabbit |
| W Pinto, G Battagli. Comparative recovery kinetics of 5-hydroxytryptamine 1A, 1B, and 2A receptor subtypes in rat cortex after receptor inactivation: evidence for differences in receptor production and degradation. Molecular pharmacology. vol 46. issue 6. 1995-02-02. PMID:7808431. |
the present study investigates the comparative repopulation kinetics of 5-hydroxytryptamine (5-ht)1a, 5-ht1b, and 5-ht2a receptors in rat cortex homogenates after irreversible receptor inactivation by n-ethoxycarbonyl-1,2-ethoxydihydroquinoline. |
1995-02-02 |
2023-08-12 |
rat |
| M el Mansari, F Radja, A Ferron, T A Reader, E Molina-Holgado, L Descarrie. Hypersensitivity to serotonin and its agonists in serotonin-hyperinnervated neostriatum after neonatal dopamine denervation. European journal of pharmacology. vol 261. issue 1-2. 1995-01-23. PMID:8001641. |
after 6-hydroxydopamine lesion in adults, neither responsiveness to 5-ht, mcpp or doi nor the density of 5-ht1b or 5-ht2a binding were significantly different from control. |
1995-01-23 |
2023-08-12 |
rat |
| M el Mansari, F Radja, A Ferron, T A Reader, E Molina-Holgado, L Descarrie. Hypersensitivity to serotonin and its agonists in serotonin-hyperinnervated neostriatum after neonatal dopamine denervation. European journal of pharmacology. vol 261. issue 1-2. 1995-01-23. PMID:8001641. |
thus, the up-regulation of 5-ht1b, 5-ht2a and possibly 5-ht2c receptors accompanying the 5-ht hyperinnervation after neonatal but not after adult dopamine denervation was associated with increased responsiveness (it50) of neostriatal neurons to iontophoresed 5-ht and its receptor agonists. |
1995-01-23 |
2023-08-12 |
rat |
| H Gozlan, A M Laporte, S Thibault, L E Schechter, F Bolaños, M Hamo. Differential effects of N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) on various 5-HT receptor binding sites in the rat brain. Neuropharmacology. vol 33. issue 3-4. 1994-12-30. PMID:7984280. |
the effects of n-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (eedq), an alkylating agent producing irreversible blockade of various membrane bound receptors in brain, were investigated on four different types of serotonin receptors, 5-ht1a, 5-ht1b, 5-ht2a and 5-ht3, in various brain regions in the rat. |
1994-12-30 |
2023-08-12 |
rat |