| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Youn Hee Nam, Hoa Thi Le, Isabel Rodriguez, Eun Young Kim, Keonwoo Kim, Seo Yule Jeong, Sang Ho Woo, Yeong Ro Lee, Rodrigo Castañeda, Jineui Hong, Min Gun Ji, Ung-Jin Kim, Bin Na Hong, Tae Woo Kim, Tong Ho Kan. Enhanced antidiabetic efficacy and safety of compound K⁄β-cyclodextrin inclusion complex in zebrafish. Journal of ginseng research. vol 41. issue 1. 2020-10-01. PMID:28123328. |
20(s)-protopanaxadiol 20-o-d-glucopyranoside, also called compound k (ck), exerts antidiabetic effects that are mediated by insulin secretion through adenosine triphosphate (atp)-sensitive potassium (k |
2020-10-01 |
2023-08-13 |
zebrafish |
| Weijie Chen, Junlian Wang, Yong Luo, Tao Wang, Xiaochun Li, Aiyun Li, Jia Li, Kang Liu, Baolin Li. Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue. Journal of ginseng research. vol 40. issue 4. 2020-09-30. PMID:27746687. |
this study was designed to investigate whether ginsenoside rb1 (rb1) and compound k (ck) ameliorated insulin resistance by suppressing endoplasmic reticulum (er) stress-induced inflammation in adipose tissue. |
2020-09-30 |
2023-08-13 |
Not clear |
| Michał Wilk, Małgorzata Michalczyk, Artur Gołaś, Michał Krzysztofik, Adam Maszczyk, Adam Zają. Endocrine responses following exhaustive strength exercise with and without the use of protein and protein-carbohydrate supplements. Biology of sport. vol 35. issue 4. 2020-02-25. PMID:30765926. |
the aim of this study was to determine the effect of carbohydrate-protein supplementation with whey protein (cho-prow) after resistance training, and casein protein (proc) before bedtime on the concentration of growth hormone (gh), insulin (i) and insulin-like growth factor (igf-1), as well as serum creatine kinase (ck) activity. |
2020-02-25 |
2023-08-13 |
human |
| Xiaohui Wu, Jun Xu, Jinhu Wang, Weizhong Gu, Chaochun Zo. Childhood adrenocortical tumor: A clinical and immunohistochemical study of 13 cases. Medicine. vol 98. issue 46. 2019-12-06. PMID:31725643. |
immunohistochemistry of vimentin, chromogranin a, s100, synaptophysin, cytokeratin (ck), type 2 3β-hydroxysteroid dehydrogenase (3βhsd), cytochrome p45017α, p53, p21, p27, cyclin d1, ki-67, insulin growth facter-2 (igf-2), and β-catenin were undertaken for 13 tumors and 3 adjacent normal tissues. |
2019-12-06 |
2023-08-13 |
Not clear |
| Meng Zhang, Huizhen Zhang, Chun Liu, Xuehui Li, Mingying Ling, Zhihao Wang, Yanqiu Xin. Myocardial Protective Effects of Nicorandil on Rats with Type 2 Diabetic Cardiomyopathy. Medical science monitor basic research. vol 24. 2018-12-11. PMID:30262799. |
the serum lipoids, plasma glucose, insulin levels, heart weight index, serum creatine kinase (ck), lactate dehydrogenase (ldh) levels, superoxide dismutase (sod) activity, and malondialdehyde (mda) were analyzed in all groups. |
2018-12-11 |
2023-08-13 |
rat |
| Douglas K da Silva, Jeferson L Jacinto, Walquiria B de Andrade, Mirela C Roveratti, José M Estoche, Mario C W Balvedi, Douglas B de Oliveira, Rubens A da Silva, Andreo F Aguia. Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men. Nutrients. vol 9. issue 10. 2018-06-18. PMID:29057836. |
during the tests sessions, we assessed the following variables: number of maximum repetitions, electromyographic signal (i.e., root mean square (rms) and median frequency (mf)), muscle soreness and perceived exertion, as well as blood levels of creatine kinase (ck), lactate, insulin, and testosterone:cortisol ratio. |
2018-06-18 |
2023-08-13 |
Not clear |
| Florian M Trefz, Ingrid Loren. Plasma potassium concentrations in neonatal diarrhoeic calves are correlated with serum aldosterone concentrations but not with insulin concentrations. Veterinary journal (London, England : 1997). vol 230. 2018-04-27. PMID:29208215. |
the present study assessed the association of plasma potassium (ck) with serum aldosterone and insulin concentrations, since these hormones are involved in the regulation of potassium homeostasis. |
2018-04-27 |
2023-08-13 |
Not clear |
| Yentl C Haan, Inge Oudman, Frederieke S Diemer, Fares A Karamat, Irene G van Valkengoed, Gert A van Montfrans, Lizzy M Brewste. Creatine kinase as a marker of obesity in a multi-ethnic population. Molecular and cellular endocrinology. vol 442. 2017-10-30. PMID:27894867. |
creatine kinase (ck), the central regulatory enzyme of energy metabolism, is particularly high in type ii skeletal muscle fibers, which are associated with insulin resistance and obesity. |
2017-10-30 |
2023-08-13 |
Not clear |
| Liam D Harper, Robert Hunter, Paul Parker, Stuart Goodall, Kevin Thomas, Glyn Howatson, Daniel J West, Emma Stevenson, Mark Russel. Test-Retest Reliability of Physiological and Performance Responses to 120 Minutes of Simulated Soccer Match Play. Journal of strength and conditioning research. vol 30. issue 11. 2016-12-15. PMID:26950356. |
moderate reliability was demonstrated for 15-m sprint speed (4.6%, 0.36), dribble precision (11.5%, 0.30), plasma insulin (10.3%, 0.96), creatine kinase ([ck] 28.1%, 0.38), interleukin-6 (24%, 0.99), nonesterified fatty acids ([nefa] 13.2%, 0.73), glycerol (12.5%, 0.86), and blood lactate (18.6%, 0.79). |
2016-12-15 |
2023-08-13 |
Not clear |
| H Hu, X Bai, A A Shah, A Y Wen, J L Hua, C Y Che, S J He, J P Jiang, Z H Cai, S F Da. Dietary supplementation with glutamine and γ-aminobutyric acid improves growth performance and serum parameters in 22- to 35-day-old broilers exposed to hot environment. Journal of animal physiology and animal nutrition. vol 100. issue 2. 2016-12-14. PMID:25980810. |
compared with the positive control group, the cycling high temperature decreased (p < 0.05) the feed consumption, weight gain and serum total protein (tp), glucose, thyroxine (t4), insulin, alkaline phosphatase (alp), glutamine, gaba and glutamate levels, while increased (p < 0.05) the serum triglyceride (tg), corticosterone (cs), glucagon (gn), creatine kinase (ck), glutamic oxaloacetic transaminase (got), nitric oxide synthase (nos), glutamate pyruvate transaminase (gpt) and lactate dehydrogenase (ldh) levels during 22-35 days. |
2016-12-14 |
2023-08-13 |
Not clear |
| H Hu, X Bai, A A Shah, A Y Wen, J L Hua, C Y Che, S J He, J P Jiang, Z H Cai, S F Da. Dietary supplementation with glutamine and γ-aminobutyric acid improves growth performance and serum parameters in 22- to 35-day-old broilers exposed to hot environment. Journal of animal physiology and animal nutrition. vol 100. issue 2. 2016-12-14. PMID:25980810. |
however, dietary glutamine (5 g/kg) increased (p < 0.05) the feed consumption, weight gain and serum levels of glutamine, tp, insulin and alp, but decreased (p < 0.05) the serum tg, ck, got, nos and gpt levels. |
2016-12-14 |
2023-08-13 |
Not clear |
| C L Francisco, F D Resende, J M B Benatti, A M Castilhos, R F Cooke, A M Jorg. Impacts of temperament on Nellore cattle: physiological responses, feedlot performance, and carcass characteristics. Journal of animal science. vol 93. issue 11. 2016-08-17. PMID:26641061. |
blood samples were collected at 0, 67, and 109 d and analyzed for serum variables (cortisol, insulin, haptoglobin, total protein, lactate, creatinine kinase [ck], lactate dehydrogenase [ldh], and iga). |
2016-08-17 |
2023-08-13 |
cattle |
| Anne Hecksteden, Sabrina Skorski, Sascha Schwindling, Daniel Hammes, Mark Pfeiffer, Michael Kellmann, Alexander Ferrauti, Tim Meye. Blood-Borne Markers of Fatigue in Competitive Athletes - Results from Simulated Training Camps. PloS one. vol 11. issue 2. 2016-07-26. PMID:26891051. |
with cycling, a fatigue dependent course was observed for creatine kinase (ck; Δfatigue 54±84 u/l; Δrecovery -60±83 u/l), urea (Δfatigue 11±9 mg/dl; Δrecovery -10±10 mg/dl), free testosterone (Δfatigue -1.3±2.1 pg/ml; Δrecovery 0.8±1.5 pg/ml) and insulin linke growth factor 1 (igf-1; Δfatigue -56±28 ng/ml; Δrecovery 53±29 ng/ml). |
2016-07-26 |
2023-08-13 |
human |
| R Nakahira, M Michishita, H Yoshimura, H Hatakeyama, K Takahash. Neuroendocrine carcinoma of the mammary gland in a dog. Journal of comparative pathology. vol 152. issue 2-3. 2016-01-13. PMID:25670668. |
immunohistochemically, most tumour cells expressed cytokeratin (ck) 20, chromogranin a, neuron-specific enolase, synaptophysin and oestrogen receptor-β, but not low molecular weight ck (cam5.2), p63 and insulin. |
2016-01-13 |
2023-08-13 |
dog |
| Eman AbdElmonem Elbassuon. Incretin attenuates diabetes-induced damage in rat cardiac tissue. The journal of physiological sciences : JPS. vol 64. issue 5. 2015-05-12. PMID:25011640. |
the following parameters were measured: in blood: glucose, insulin, lactate dehydrogenase (ldh), total creatine kinase (ck), creatine kinase mb isoenzyme (ck-mb), and ck-mb relative index; in cardiac tissue: lipid peroxide (lpo) and some antioxidant enzymes. |
2015-05-12 |
2023-08-13 |
rat |
| Shuang Jiang, Dayong Ren, Jianrui Li, Guangxin Yuan, Hongyu Li, Guangyu Xu, Xiao Han, Peige Du, Liping A. Effects of compound K on hyperglycemia and insulin resistance in rats with type 2 diabetes mellitus. Fitoterapia. vol 95. 2015-01-07. PMID:24613802. |
it is concluded from the results that ck may have improving effects on hyperglycemia and insulin resistance of diabetic rats. |
2015-01-07 |
2023-08-12 |
rat |
| Shuang Jiang, Dayong Ren, Jianrui Li, Guangxin Yuan, Hongyu Li, Guangyu Xu, Xiao Han, Peige Du, Liping A. Effects of compound K on hyperglycemia and insulin resistance in rats with type 2 diabetes mellitus. Fitoterapia. vol 95. 2015-01-07. PMID:24613802. |
these results indicate that the hypoglycemic activity of ck is mediated by improvement of insulin sensitivity, which is closely related to pi3k/akt signaling pathway. |
2015-01-07 |
2023-08-12 |
rat |
| Jian Gu, Wei Li, Dong Xiao, ShengNan Wei, WanLi Cui, WeiJia Chen, YaLi Hu, XiaoJia Bi, YongChol Kim, Jing Li, HongWei Du, Ming Zhang, Li Che. Compound K, a final intestinal metabolite of ginsenosides, enhances insulin secretion in MIN6 pancreatic β-cells by upregulation of GLUT2. Fitoterapia. vol 87. 2014-01-16. PMID:23558203. |
although it has also been found to have the property of anti-diabetes, the long-term effect of ck on insulin secretion in β-cells is still unclear. |
2014-01-16 |
2023-08-12 |
Not clear |
| Jian Gu, Wei Li, Dong Xiao, ShengNan Wei, WanLi Cui, WeiJia Chen, YaLi Hu, XiaoJia Bi, YongChol Kim, Jing Li, HongWei Du, Ming Zhang, Li Che. Compound K, a final intestinal metabolite of ginsenosides, enhances insulin secretion in MIN6 pancreatic β-cells by upregulation of GLUT2. Fitoterapia. vol 87. 2014-01-16. PMID:23558203. |
in this study, ck was prepared from ginsenoside rd by snailase hydrolysis and its effect on the insulin secretion activity in min6 pancreatic β-cell lines in vitro was assessed. |
2014-01-16 |
2023-08-12 |
Not clear |
| Jian Gu, Wei Li, Dong Xiao, ShengNan Wei, WanLi Cui, WeiJia Chen, YaLi Hu, XiaoJia Bi, YongChol Kim, Jing Li, HongWei Du, Ming Zhang, Li Che. Compound K, a final intestinal metabolite of ginsenosides, enhances insulin secretion in MIN6 pancreatic β-cells by upregulation of GLUT2. Fitoterapia. vol 87. 2014-01-16. PMID:23558203. |
the results showed that ck significantly enhanced insulin secretion, increased cellular atp content, and upregulated the expression of glut2. |
2014-01-16 |
2023-08-12 |
Not clear |