| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lu-Fan Li, Jie Yang, Shi-Ping Ma, Rong Q. Magnolol treatment reversed the glial pathology in an unpredictable chronic mild stress-induced rat model of depression. European journal of pharmacology. vol 711. issue 1-3. 2014-04-28. PMID:23632393. |
in addition, the levels of glial fibrillary acidic protein (gfap), an astrocyte marker, in the hippocampus and prefrontal cortex were determined by immunohistochemistry, western blot, and reverse transcription-polymerase chain reaction (rt-pcr). |
2014-04-28 |
2023-08-12 |
rat |
| Ayodeji A Asuni, Bryony Gray, Joanne Bailey, Paul Skipp, V Hugh Perry, Vincent O'Conno. Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration. The Journal of biological chemistry. vol 289. issue 7. 2014-04-28. PMID:24366862. |
four of the up-regulated proteins (gfap, high affinity glutamate transporter (eaat-2), apo-j (clusterin), and peroxiredoxin-6) are selectively expressed in astrocytes, but astrocyte proliferation does not contribute to their up-regulation. |
2014-04-28 |
2023-08-12 |
Not clear |
| Grazyna Rajkowska, Craig A Stockmeie. Astrocyte pathology in major depressive disorder: insights from human postmortem brain tissue. Current drug targets. vol 14. issue 11. 2014-04-14. PMID:23469922. |
this review summarizes evidence from human postmortem tissue showing alterations in the expression of protein and mrna for astrocyte markers such as glial fibrillary acidic protein (gfap), gap junction proteins (connexin 40 and 43), the water channel aquaporin-4 (aqp4), a calcium-binding protein s100b and glutamatergic markers including the excitatory amino acid transporters 1 and 2 (eaat1, eaat2) and glutamine synthetase. |
2014-04-14 |
2023-08-12 |
human |
| N Rajasekar, Subhash Dwivedi, Santosh Kumar Tota, Pradeep Kumar Kamat, Kashif Hanif, Chandishwar Nath, Rakesh Shukl. Neuroprotective effect of curcumin on okadaic acid induced memory impairment in mice. European journal of pharmacology. vol 715. issue 1-3. 2014-04-14. PMID:23685326. |
curcumin also inhibited astrocyte activation as evidenced by decreased gfap expression. |
2014-04-14 |
2023-08-12 |
mouse |
| Mauricio Sandoval, Alejandro Luarte, Rodrigo Herrera-Molina, Manuel Varas-Godoy, Marcos Santibáñez, Francisco J Rubio, August B Smit, Eckart D Gundelfinger, Ka-Wan Li, Karl-Heinz Smalla, Ursula Wyneke. The glycolytic enzyme aldolase C is up-regulated in rat forebrain microsomes and in the cerebrospinal fluid after repetitive fluoxetine treatment. Brain research. vol 1520. 2014-04-11. PMID:23688545. |
an immunohistochemical analysis of the dorsal hippocampus revealed a robust decrease (43±2%) in the co-localization of aldoc and the astrocyte marker gfap and a diffuse staining pattern, compatible with aldoc secretion into the extracellular space. |
2014-04-11 |
2023-08-12 |
rat |
| Ron Bouchard, Thomas Chong, Subbiah Pugazhenth. Laser capture microdissection of neurons from differentiated human neuroprogenitor cells in culture. Journal of visualized experiments : JoVE. issue 79. 2014-04-10. PMID:24084642. |
glial fibrillary acidic protein (gfap) and stat3, astrocyte markers, were detected in 10-15% of differentiated npcs. |
2014-04-10 |
2023-08-12 |
mouse |
| Alexander A Sosunov, Xiaoping Wu, Nadejda M Tsankova, Eileen Guilfoyle, Guy M McKhann, James E Goldma. Phenotypic heterogeneity and plasticity of isocortical and hippocampal astrocytes in the human brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 6. 2014-04-01. PMID:24501367. |
cd44 antibodies outline the details of astrocyte morphology to a degree not possible with glial fibrillary acidic protein (gfap) antibodies. |
2014-04-01 |
2023-08-12 |
human |
| Katrina Owens, Ji H Park, Tibor Kristia. Utilizing commercial microwave for rapid and effective immunostaining. Journal of neuroscience methods. vol 219. issue 1. 2014-03-28. PMID:23856210. |
this technique was used on mouse brain sections that were immunostained with microglia-specific cd68 antiserum and astrocyte labeling gfap antibody. |
2014-03-28 |
2023-08-12 |
mouse |
| Takeyuki Yamada, Yumiko Urano-Tashiro, Yoshimi Hashi, Marimu Sakumoto, Hirotada Akiyama, Fumio Tashir. The U-box-type ubiquitin ligase PRP19β regulates astrocyte differentiation via ubiquitination of PTP1B. Brain research. vol 1524. 2014-03-14. PMID:23769735. |
only overexpression of prp19β conferred astrocyte properties at a certain level, and induced more astrocyte markers, glial fibrillary acidic protein (gfap) and s100β, in the presence of camp, whereas its down-regulation by antisense rna showed a suppressive effect. |
2014-03-14 |
2023-08-12 |
Not clear |
| Daniel Andersson, Ulrika Wilhelmsson, Michael Nilsson, Mikael Kubista, Anders Ståhlberg, Marcela Pekna, Milos Pekn. Plasticity response in the contralesional hemisphere after subtle neurotrauma: gene expression profiling after partial deafferentation of the hippocampus. PloS one. vol 8. issue 7. 2014-03-05. PMID:23936241. |
to test whether astrocyte activation plays a role in the observed plasticity response to ecl, we took advantage of mice deficient in two intermediate filament (nanofilament) proteins glial fibrillary acidic protein (gfap) and vimentin (gfap(-/-)vim(-/-) ) and exhibiting attenuated astrocyte activation and reactive gliosis. |
2014-03-05 |
2023-08-12 |
mouse |
| Daniel Andersson, Ulrika Wilhelmsson, Michael Nilsson, Mikael Kubista, Anders Ståhlberg, Marcela Pekna, Milos Pekn. Plasticity response in the contralesional hemisphere after subtle neurotrauma: gene expression profiling after partial deafferentation of the hippocampus. PloS one. vol 8. issue 7. 2014-03-05. PMID:23936241. |
the absence of gfap and vimentin reduced the ecl-induced upregulation of thrombospondin 4, indicating that this response to ecl depends on astrocyte activation and reactive gliosis. |
2014-03-05 |
2023-08-12 |
mouse |
| Tulen Pekny, Maryam Faiz, Ulrika Wilhelmsson, Maurice A Curtis, Radoslav Matej, Omar Skalli, Milos Pekn. Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 122. issue 1. 2014-02-25. PMID:23594359. |
axd is caused by mutations in gfap, the main astrocyte intermediate filament protein. |
2014-02-25 |
2023-08-12 |
Not clear |
| Jin Seon Kwon, Gyeong Hae Kim, Da Yeon Kim, So Mi Yoon, Hyo Won Seo, Jae Ho Kim, Byoung Hyun Min, Moon Suk Ki. Chitosan-based hydrogels to induce neuronal differentiation of rat muscle-derived stem cells. International journal of biological macromolecules. vol 51. issue 5. 2014-02-24. PMID:22922106. |
on chitosan hydrogel in the presence of va, rmdscs exhibited higher expression of the neural markers, neuron-specific enolase (nse) and beta tubulin iii (tuj-1), the oligodendrocyte marker, oligodendrocyte transcription factor 2 (olig-2), and the astrocyte marker, glial fibrillary acidic protein (gfap) than those in the absence of va. our results suggest that rmdscs on a chitosan hydrogel in the presence of va can differentiate into cells with a neural-like phenotype. |
2014-02-24 |
2023-08-12 |
rat |
| Sujeong Yeo, Susanta Bandyopadhyay, Albee Messing, Michael Brenne. Transgenic analysis of GFAP promoter elements. Glia. vol 61. issue 9. 2014-02-21. PMID:23832770. |
transcriptional regulation of the glial fibrillary acidic protein gene (gfap) is of interest because of its astrocyte specificity and its upregulation in response to cns injuries. |
2014-02-21 |
2023-08-12 |
mouse |
| Sujeong Yeo, Susanta Bandyopadhyay, Albee Messing, Michael Brenne. Transgenic analysis of GFAP promoter elements. Glia. vol 61. issue 9. 2014-02-21. PMID:23832770. |
whereas mutation of the conserved consensus ap-1 site unexpectedly had little effect on transgene expression; nfi, sp1, stat3, and nf-κb were identified as having important roles in regulating the strength of gfap promoter activity and/or its astrocyte specificity. |
2014-02-21 |
2023-08-12 |
mouse |
| Yolanda de Pablo, Michael Nilsson, Marcela Pekna, Milos Pekn. Intermediate filaments are important for astrocyte response to oxidative stress induced by oxygen-glucose deprivation and reperfusion. Histochemistry and cell biology. vol 140. issue 1. 2014-01-22. PMID:23756782. |
two cellular hallmarks of reactive gliosis are hypertrophy of astrocyte processes and upregulation of intermediate filament (nanofilament) proteins glial fibrillary acidic protein (gfap), vimentin, nestin, and synemin. |
2014-01-22 |
2023-08-12 |
mouse |
| Santiago Cuesta, Ramiro Proietto, Graciela Beatriz Garcí. Astrogliosis and HSP 70 activation in neonate rats' brain exposed to sodium metavanadate through lactation. Neurotoxicology and teratology. vol 37. 2013-12-30. PMID:23557781. |
the relative optical density of the nadphd stained layers and of s100 (+) astrocytes and the gfap (+) astrocyte surface area in cer and hc were measured. |
2013-12-30 |
2023-08-12 |
rat |
| Liyun Zeng, Peilin Zhang, Lingling Shi, Vicky Yamamoto, Wange Lu, Kai Wan. Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models. PloS one. vol 8. issue 3. 2013-12-27. PMID:23536886. |
furthermore, astrocyte marker gfap was significantly reduced in a time dependent manner that correlated with nrxn1 reduction. |
2013-12-27 |
2023-08-12 |
human |
| H Imbe, A Kimura, T Donishi, Y Kaneok. Effects of restraint stress on glial activity in the rostral ventromedial medulla. Neuroscience. vol 241. 2013-12-12. PMID:23518226. |
postmortem studies of patients with stress-related psychiatric disorders have demonstrated a decrease in the number of astrocytes and the level of glial fibrillary acidic protein (gfap), a marker for astrocyte, in the cerebral cortex. |
2013-12-12 |
2023-08-12 |
rat |
| Daniel-Christoph Wagner, Johanna Scheibe, Isabelle Glocke, Gesa Weise, Alexander Deten, Johannes Boltze, Alexander Kran. Object-based analysis of astroglial reaction and astrocyte subtype morphology after ischemic brain injury. Acta neurobiologiae experimentalis. vol 73. issue 1. 2013-12-10. PMID:23595285. |
gfap stained most of the astrocyte processes and is hence suitable for the analysis of qualitative characteristics of astrogliosis. |
2013-12-10 |
2023-08-12 |
rat |