| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Morgenweck, R B Griggs, R R Donahue, J E Zadina, B K Taylo. PPARγ activation blocks development and reduces established neuropathic pain in rats. Neuropharmacology. vol 70. 2013-11-26. PMID:23415633. |
intraperitoneal pioglitazone significantly reduced the nerve injury-induced up-regulation of cd11b, gfap, and p-p38 in the dorsal horn, indicating a mechanism of action involving spinal microglia and/or astrocyte activation. |
2013-11-26 |
2023-08-12 |
rat |
| Laura B Buckman, Misty M Thompson, Heidi N Moreno, Kate L J Ellacot. Regional astrogliosis in the mouse hypothalamus in response to obesity. The Journal of comparative neurology. vol 521. issue 6. 2013-10-29. PMID:23047490. |
we used immunohistochemistry to examine the differential distribution of the astrocyte marker glial-fibrillary acidic protein (gfap) in the brains of diet-induced or genetically obese mice compared with their respective lean controls to determine whether different nuclei of the hypothalamus showed comparable astrogliosis in response to obesity. |
2013-10-29 |
2023-08-12 |
mouse |
| Ross J Tynan, Sarah B Beynon, Madeleine Hinwood, Sarah J Johnson, Michael Nilsson, Jason J Woods, Frederick R Walke. Chronic stress-induced disruption of the astrocyte network is driven by structural atrophy and not loss of astrocytes. Acta neuropathologica. vol 126. issue 1. 2013-10-28. PMID:23512378. |
we further established that while chronic stress was associated with a decrease in astrocyte numbers when gfap labelling was used as a marker, we could find no evidence of a decrease in the total number of cells, based on nissl staining, or in the number of s100β⁺ cells. |
2013-10-28 |
2023-08-12 |
rat |
| Ross J Tynan, Sarah B Beynon, Madeleine Hinwood, Sarah J Johnson, Michael Nilsson, Jason J Woods, Frederick R Walke. Chronic stress-induced disruption of the astrocyte network is driven by structural atrophy and not loss of astrocytes. Acta neuropathologica. vol 126. issue 1. 2013-10-28. PMID:23512378. |
this finding suggests that chronic stress may not actually reduce astrocyte numbers and may instead selectively decrease gfap expression. |
2013-10-28 |
2023-08-12 |
rat |
| Debora Lo Furno, Rosalia Pellitteri, Adriana C E Graziano, Rosario Giuffrida, Carlo Vancheri, Elisa Gili, Venera Cardil. Differentiation of human adipose stem cells into neural phenotype by neuroblastoma- or olfactory ensheathing cells-conditioned medium. Journal of cellular physiology. vol 228. issue 11. 2013-09-30. PMID:23589068. |
the results showed that both oecs- or b104-cm treated at-mscs express markers of progenitor and mature neurons (nestin, pgp 9.5 and map2) in time-dependent manner, display morphological features resembling neuronal cells, and result negative for gfap and a2b5, astrocyte and oligodendrocyte markers, respectively. |
2013-09-30 |
2023-08-12 |
human |
| Xijuan Wang, Liwen Chang, Zhibao Guo, Wenbin Li, Wei Liu, Baohuan Cai, Jing Wan. Neonatal SVZ EGFP-labeled cells produce neurons in the olfactory bulb and astrocytes in the cerebral cortex by in-vivo electroporation. Neuroreport. vol 24. issue 7. 2013-09-27. PMID:23568218. |
the results showed that egfp-positive cells were distributed mainly in the olfactory bulb (ob), cortex, and svz, and double labeled with neun (neuron marker) in ob, glial fibrillary acidic protein (gfap) (astrocyte marker) in the cortex, and blbp and gfap (astrocyte marker) in svz. |
2013-09-27 |
2023-08-12 |
mouse |
| S Gutierrez, K Hayashida, J C Eisenac. The puerperium alters spinal cord plasticity following peripheral nerve injury. Neuroscience. vol 228. 2013-09-23. PMID:23103215. |
astrocyte activation, as measured by glial fibrillary acidic protein (gfap) expression, was not evident in female rats with injury, regardless of delivery status suggesting sex differences in spinal astrocyte activation after injury. |
2013-09-23 |
2023-08-12 |
rat |
| Mohammad Moshahid Khan, Duraisamy Kempuraj, Ramasamy Thangavel, Asgar Zahee. Protection of MPTP-induced neuroinflammation and neurodegeneration by Pycnogenol. Neurochemistry international. vol 62. issue 4. 2013-09-20. PMID:23391521. |
this was associated with significantly increased inflammatory responses of astrocyte and microglia as assessed by ionized calcium binding adaptor molecule 1 (iba 1) and glial fibrillary acidic protein (gfap) immunohistochemistry, and nuclear transcription factor-κb (nf-κb), inducible nitric oxide synthase (inos) and cyclooxygenase-2 (cox-2) expression in the striata by western blot. |
2013-09-20 |
2023-08-12 |
mouse |
| Jie Lu, Jason M Frerich, L Christine Turtzo, Siqi Li, Jeffrey Chiang, Chunzhang Yang, Xiaoping Wang, Chao Zhang, Chenxi Wu, Zhongchan Sun, Gang Niu, Zhengping Zhuang, Roscoe O Brady, Xiaoyuan Che. Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 26. 2013-09-06. PMID:23754423. |
hdaci treatment also increased the expression of the stem cell biomarker nestin, and decreased the expression of reactive astrocyte biomarker gfap within damaged tissue following tbi. |
2013-09-06 |
2023-08-12 |
rat |
| Leila Miguel Stavale, Edilene Siqueira Soares, Monique C P Mendonça, Silvia P Irazusta, Maria Alice da Cruz Höflin. Temporal relationship between aquaporin-4 and glial fibrillary acidic protein in cerebellum of neonate and adult rats administered a BBB disrupting spider venom. Toxicon : official journal of the International Society on Toxinology. vol 66. 2013-09-03. PMID:23419593. |
two astrocyte markers, the glial water channel aquaporin-4 (aqp4) and the glial fibrillary acidic protein (gfap), have been implicated in several physiological and pathological conditions in the central nervous system (cns) as well as in blood-brain barrier breakdown (bbbb). |
2013-09-03 |
2023-08-12 |
rat |
| Katarzyna J Radomska, Jonatan Halvardson, Björn Reinius, Eva Lindholm Carlström, Lina Emilsson, Lars Feuk, Elena Jazi. RNA-binding protein QKI regulates Glial fibrillary acidic protein expression in human astrocytes. Human molecular genetics. vol 22. issue 7. 2013-08-28. PMID:23321059. |
we found that an mrna expression of glial fibrillary acidic protein (gfap), encoding a major component of astrocyte intermediate filaments, was down-regulated after qki7 splice variant silencing. |
2013-08-28 |
2023-08-12 |
mouse |
| Ji Young Kim, Gyu-Sik Choi, Yun-Woo Cho, Heekyung Cho, Se-Jin Hwang, Sang-Ho Ah. Attenuation of spinal cord injury-induced astroglial and microglial activation by repetitive transcranial magnetic stimulation in rats. Journal of Korean medical science. vol 28. issue 2. 2013-08-16. PMID:23399872. |
elevated expressions of iba1 and gfap, specific microglial and astrocyte markers, was respectively observed in dorsal and ventral horns at the l4 and l5 levels in sci rats. |
2013-08-16 |
2023-08-12 |
rat |
| Shen-Ting Zhao, Li Zhao, Jian-Hua L. Neuroprotective Peptide humanin inhibits inflammatory response in astrocytes induced by lipopolysaccharide. Neurochemical research. vol 38. issue 3. 2013-08-15. PMID:23277413. |
our results showed that 1.0 μg/ml lps induced a significant activation of astrocyte, shown as the marked increase in the glial fibrillary acidic protein (gfap) expression, the cell viability and the number of 5-bromo-2'-deoxyuridine (brdu)-positive living cells. |
2013-08-15 |
2023-08-12 |
Not clear |
| Matthew Roy Williams, Thomas Hampton, Ronald K B Pearce, Steven Richard Hirsch, Olaf Ansorge, Maria Thom, Michael Maie. Astrocyte decrease in the subgenual cingulate and callosal genu in schizophrenia. European archives of psychiatry and clinical neuroscience. vol 263. issue 1. 2013-08-12. PMID:22660922. |
serial coronal sections were stained with h and e for anatomical guidance, cresyl haematoxylin for oligodendrocyte identification and gfap immunohistochemistry for astrocyte identification. |
2013-08-12 |
2023-08-12 |
Not clear |
| Le Zhang, Kalavathi Dasuri, Sun-Ok Fernandez-Kim, Annadora J Bruce-Keller, Linnea R Freeman, Jennifer K Pepping, Tina L Beckett, M Paul Murphy, Jeffrey N Kelle. Prolonged diet induced obesity has minimal effects towards brain pathology in mouse model of cerebral amyloid angiopathy: implications for studying obesity-brain interactions in mice. Biochimica et biophysica acta. vol 1832. issue 9. 2013-08-08. PMID:23313575. |
in these studies we identify surprisingly that dio does not significantly increase aβ levels, astrocyte (gfap) or microglial (iba-1) gliosis in the caa mice. |
2013-08-08 |
2023-08-12 |
mouse |
| Jason M Arimoto, Angela Wong, Irina Rozovsky, Sharon W Lin, Todd E Morgan, Caleb E Finc. Age increase of estrogen receptor-α (ERα) in cortical astrocytes impairs neurotrophic support in male and female rats. Endocrinology. vol 154. issue 6. 2013-07-25. PMID:23515288. |
because elevated expression of astrocyte glial fibrillary acidic protein (gfap) is associated with impaired neurotrophic activity and because the gfap promoter responds to erα, we investigated the role of astrocytic erα and erβ in impaired astrocyte neurotrophic activity during aging. |
2013-07-25 |
2023-08-12 |
rat |
| Seo-Yeon Yoon, Caleb R Robinson, Haijun Zhang, Patrick M Doughert. Spinal astrocyte gap junctions contribute to oxaliplatin-induced mechanical hypersensitivity. The journal of pain. vol 14. issue 2. 2013-07-11. PMID:23374942. |
blockade of astrocyte gap junction with carbenoxolone (cbx) prevented oxaliplatin-induced mechanical hypersensitivity in a dose-dependent manner and the increase of spinal gfap expression, but had no effect once the mechanical hypersensitivity induced by oxaliplatin had fully developed. |
2013-07-11 |
2023-08-12 |
Not clear |
| Luana Heimfarth, Samanta Oliveira Loureiro, Márcio Ferreira Dutra, Letícia Petenuzzo, Bárbara Ortiz de Lima, Carolina Gonçalves Fernandes, João Batista Teixeira da Rocha, Regina Pessoa-Pureu. Disrupted cytoskeletal homeostasis, astrogliosis and apoptotic cell death in the cerebellum of preweaning rats injected with diphenyl ditelluride. Neurotoxicology. vol 34. 2013-07-09. PMID:23182946. |
the earlier responses, at day 3 after injection, included hyperphosphorylation of intermediate filament (if) proteins from astrocyte (glial fibrillary acidic protein - gfap - and vimentin) and neuron (low-, medium- and high molecular weight neurofilament subunits: nf-l, nf-m and nf-h); increased mitogen-activated protein kinase (mapk) (erk and p38mapk) and camp-dependent protein kinase (pka) activities. |
2013-07-09 |
2023-08-12 |
rat |
| Nguyen Huy Binh, Kunio Satoh, Kazuhiro Kobayashi, Manabu Takamatsu, Yuichiro Hatano, Akihiro Hirata, Hiroyuki Tomita, Toshiya Kuno, Akira Har. Galectin-3 in preneoplastic lesions of glioma. Journal of neuro-oncology. vol 111. issue 2. 2013-06-26. PMID:23179497. |
in the present study, expression of galectin-3 in ethylnitrosourea-induced rat gliomas including preneoplastic and neoplastic lesions was examined by immunohistochemistry for galectin-3, iba-1 (a specific microglial cell marker), gfap (a specific astrocyte cell marker), and conventional hematoxylin and eosin staining (for morphological observation). |
2013-06-26 |
2023-08-12 |
human |
| Alexander A Sosunov, Eileen Guilfoyle, Xiaoping Wu, Guy M McKhann, James E Goldma. Phenotypic conversions of "protoplasmic" to "reactive" astrocytes in Alexander disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 17. 2013-06-25. PMID:23616550. |
alexander disease (axd) is a primary disorder of astrocytes, caused by heterozygous mutations in gfap, which encodes the major astrocyte intermediate filament protein, glial fibrillary acidic protein (gfap). |
2013-06-25 |
2023-08-12 |
mouse |