| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julia E Herrmann, Tetsuya Imura, Bingbing Song, Jingwei Qi, Yan Ao, Thu K Nguyen, Rose A Korsak, Kiyoshi Takeda, Shizuo Akira, Michael V Sofronie. STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 28. 2008-08-12. PMID:18614693. |
mice with stat3-cko from astrocytes exhibited attenuated upregulation of gfap, failure of astrocyte hypertrophy, and pronounced disruption of astroglial scar formation after sci. |
2008-08-12 |
2023-08-12 |
mouse |
| Beatriz Cebolla, Antonio Fernández-Pérez, Gertrudis Perea, Alfonso Araque, Mario Vallej. DREAM mediates cAMP-dependent, Ca2+-induced stimulation of GFAP gene expression and regulates cortical astrogliogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 26. 2008-08-05. PMID:18579744. |
these results identify the pacap-camp-ca(2+)-dream cascade as a new pathway to activate gfap gene expression during astrocyte differentiation. |
2008-08-05 |
2023-08-12 |
mouse |
| Alessandra Swarowsky, Letícia Rodrigues, Regina Biasibetti, Marina C Leite, Lucas Fürstenau de Oliveira, Lucia M V de Almeida, Carmem Gottfried, Jorge A Quillfeldt, Matilde Achaval, Carlos-Alberto Gonçalve. Glial alterations in the hippocampus of rats submitted to ibotenic-induced lesion of the nucleus basalis magnocellularis. Behavioural brain research. vol 190. issue 2. 2008-07-30. PMID:18395808. |
in this study, we investigated possible specific astrocyte alterations in the hippocampi of wistar rats submitted to nbm damage with ibotenic acid, investigating the content and immunohistochemistry of glial fibrillary acidic protein (gfap), as well as s100b protein content, glutamate uptake and glutamine synthetase activity on the 7th and 28th post-lesion days. |
2008-07-30 |
2023-08-12 |
rat |
| Z Zhang, Z-Y Zhang, U Fauser, H J Schluesene. Mechanical allodynia and spinal up-regulation of P2X4 receptor in experimental autoimmune neuritis rats. Neuroscience. vol 152. issue 2. 2008-07-10. PMID:18276080. |
double staining revealed that almost all p2x(4)r(+) cells co-expressed cd68, a marker for reactive microglia, but not the astrocyte marker, glial fibrillary acidic protein (gfap). |
2008-07-10 |
2023-08-12 |
rat |
| Tomoya Nakamachi, Hirokazu Ohtaki, Sachiko Yofu, Kenji Dohi, Jun Watanabe, Daisuke Hayashi, Ryosuke Matsuno, Naoko Nonaka, Kazuo Itabashi, Seiji Shiod. Pituitary adenylate cyclase-activating polypeptide (PACAP) type 1 receptor (PAC1R) co-localizes with activity-dependent neuroprotective protein (ADNP) in the mouse brains. Regulatory peptides. vol 145. issue 1-3. 2008-05-06. PMID:17942168. |
adnp-immunoreactive cells in the cerebral cortex were multi-polar-shaped and co-immunostained with the astrocyte marker, glial fibrillary acidic protein (gfap). |
2008-05-06 |
2023-08-12 |
mouse |
| Anindita Joardar, Sumantra Da. Effect of fatty acids isolated from edible oils like mustard, linseed or coconut on astrocytes maturation. Cellular and molecular neurobiology. vol 27. issue 8. 2008-05-01. PMID:17823864. |
the expression profile of the isoforms of gfap showed that astrocyte maturation by fas of mustard and linseed oil was associated with appearance of acidic variants of gfap and disappearance of some neutral isoforms similar to that observed in cultures grown in serum containing medium or in the presence of dha. |
2008-05-01 |
2023-08-12 |
human |
| Stefan Spulber, Mircea Oprica, Tamas Bartfai, Bengt Winblad, Marianne Schultzber. Blunted neurogenesis and gliosis due to transgenic overexpression of human soluble IL-1ra in the mouse. The European journal of neuroscience. vol 27. issue 3. 2008-04-22. PMID:18279308. |
in addition, using a novel approach to quantifying glial activation, we show that expression of the astrocyte cytoskeletal marker glial fibrillary acidic protein (gfap) following kainic acid (ka)-induced seizures or during ageing did not change in tg hsil-1ra animals. |
2008-04-22 |
2023-08-12 |
mouse |
| L Vitellaro-Zuccarello, S Mazzetti, L Madaschi, P Bosisio, E Fontana, A Gorio, S De Bias. Chronic erythropoietin-mediated effects on the expression of astrocyte markers in a rat model of contusive spinal cord injury. Neuroscience. vol 151. issue 2. 2008-04-15. PMID:18065151. |
in the present study, to better understand rhepo-mediated effects on chronic astrocyte response to sci in rat, we have used immunocytochemical methods combined with confocal and electron microscopy to investigate, 1 month after injury, the effects of a single rhepo administration on the expression of a) aquaporin 4 (aqp4), the main astrocytic water channel implicated in edema development and resolution, and two molecules (dystrophin and syntrophin) involved in its membrane anchoring; b) glial fibrillary acidic protein (gfap) and vimentin as markers of astrogliosis; c) chondroitin sulfate proteoglycans of the extracellular matrix which are upregulated after sci and can inhibit axonal regeneration and influence neuronal and glial properties. |
2008-04-15 |
2023-08-12 |
human |
| Takumi Takizawa, Prabhakar R Gudla, Liying Guo, Stephan Lockett, Tom Mistel. Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP. Genes & development. vol 22. issue 4. 2008-04-11. PMID:18281462. |
allele-specific nuclear positioning of the monoallelically expressed astrocyte marker gfap. |
2008-04-11 |
2023-08-12 |
Not clear |
| Miguel Salazar, José Antonio Pariente, Ginés María Salido, Antonio Gonzále. Ebselen increases cytosolic free Ca2+ concentration, stimulates glutamate release and increases GFAP content in rat hippocampal astrocytes. Toxicology. vol 244. issue 2-3. 2008-04-09. PMID:18237838. |
our results show that ebselen (1-20microm) dose dependently increases [ca2+](c), stimulates glutamate release and increases gfap content, a hallmark of astrocyte reactivity. |
2008-04-09 |
2023-08-12 |
rat |
| Ana Gadea, Sergio Schinelli, Vittorio Gall. Endothelin-1 regulates astrocyte proliferation and reactive gliosis via a JNK/c-Jun signaling pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 10. 2008-04-07. PMID:18322086. |
reactive gliosis is characterized by enhanced glial fibrillary acidic protein (gfap) expression, cellular hypertrophy, and astrocyte proliferation. |
2008-04-07 |
2023-08-12 |
Not clear |
| Ana Gadea, Sergio Schinelli, Vittorio Gall. Endothelin-1 regulates astrocyte proliferation and reactive gliosis via a JNK/c-Jun signaling pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 10. 2008-04-07. PMID:18322086. |
we show that et-1 levels are upregulated in demyelinated lesions within 5 d after lpc injection, together with enhanced astrocyte proliferation, gfap expression, and jnk phosphorylation. |
2008-04-07 |
2023-08-12 |
Not clear |
| Ana Gadea, Sergio Schinelli, Vittorio Gall. Endothelin-1 regulates astrocyte proliferation and reactive gliosis via a JNK/c-Jun signaling pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 10. 2008-04-07. PMID:18322086. |
in cultured astrocytes, et-1-induced activation of et(b)-rs promotes a reactive phenotype by enhancing both gfap expression and astrocyte proliferation. |
2008-04-07 |
2023-08-12 |
Not clear |
| Ana Gadea, Sergio Schinelli, Vittorio Gall. Endothelin-1 regulates astrocyte proliferation and reactive gliosis via a JNK/c-Jun signaling pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 10. 2008-04-07. PMID:18322086. |
by using selective pharmacological inhibitors, we also provide evidence that et-1 induces astrocyte proliferation and gfap expression through activation of erk- and jnk-dependent pathways, consistent with the previous observation of et-1-induced activation of erk (schinelli et al., 2001). |
2008-04-07 |
2023-08-12 |
Not clear |
| Miriam S Domowicz, Timothy A Sanders, Clifton W Ragsdale, Nancy B Schwart. Aggrecan is expressed by embryonic brain glia and regulates astrocyte development. Developmental biology. vol 315. issue 1. 2008-03-19. PMID:18207138. |
analysis of the chick aggrecan mutant nanomelia revealed marked increases in the expression of the astrocyte differentiation genes gfap, glast and gs in the absence of extracellular aggrecan. |
2008-03-19 |
2023-08-12 |
chicken |
| Wei Zou, Byung Oh Kim, Betty Y Zhou, Ying Liu, Albee Messing, Johnny J H. Protection against human immunodeficiency virus type 1 Tat neurotoxicity by Ginkgo biloba extract EGb 761 involving glial fibrillary acidic protein. The American journal of pathology. vol 171. issue 6. 2008-02-08. PMID:18055541. |
moreover, these findings suggest for the first time that gfap activation is directly involved in tat neurotoxicity, supporting the notion that astrocyte activation or astrocytosis may directly contribute to hiv-associated neurological disorders. |
2008-02-08 |
2023-08-12 |
mouse |
| John D Cahoy, Ben Emery, Amit Kaushal, Lynette C Foo, Jennifer L Zamanian, Karen S Christopherson, Yi Xing, Jane L Lubischer, Paul A Krieg, Sergey A Krupenko, Wesley J Thompson, Ben A Barre. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 1. 2008-02-07. PMID:18171944. |
we found that aldh1l1 is a highly specific antigenic marker for astrocytes with a substantially broader pattern of astrocyte expression than the traditional astrocyte marker gfap. |
2008-02-07 |
2023-08-12 |
mouse |
| Sanjay Dhar, Eul Sik Yoon, Suraj Kachgal, Gregory R D Evan. Long-term maintenance of neuronally differentiated human adipose tissue-derived stem cells. Tissue engineering. vol 13. issue 11. 2008-01-25. PMID:17914923. |
we found that the optimal differentiation protocol induced the adscs to express early neuronal markers, including nestin and neuronal nuclear antigen (neun), as well as the mature astrocyte marker glial fibrillary acidic protein (gfap). |
2008-01-25 |
2023-08-12 |
human |
| Ling-Hui Zeng, Yannan Ouyang, Vered Gazit, John R Cirrito, Laura A Jansen, Kevin C Ess, Kelvin A Yamada, David F Wozniak, David M Holtzman, David H Gutmann, Michael Won. Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex. Neurobiology of disease. vol 28. issue 2. 2008-01-11. PMID:17714952. |
mice with inactivation of the tuberous sclerosis complex-1 (tsc1) gene in glia (tsc1 gfap cko mice) have deficient astrocyte glutamate transporters and develop seizures, suggesting that abnormal glutamate homeostasis contributes to neurological abnormalities in these mice. |
2008-01-11 |
2023-08-12 |
mouse |
| Christopher M Peters, Juan Miguel Jimenez-Andrade, Michael A Kuskowski, Joseph R Ghilardi, Patrick W Manty. An evolving cellular pathology occurs in dorsal root ganglia, peripheral nerve and spinal cord following intravenous administration of paclitaxel in the rat. Brain research. vol 1168. 2008-01-09. PMID:17698044. |
in contrast, hypertrophy of drg satellite cells, hypertrophy and hyperplasia of cd68(+) macrophages in the drg and sciatic nerve, atf3 expression in s100beta(+) schwann cells and increased expression of the microglial marker (cd11b) and the astrocyte marker glial fibrillary acidic protein (gfap) in the spinal cord were not observed until day 6 post-infusion. |
2008-01-09 |
2023-08-12 |
rat |